{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T10:07:07Z","timestamp":1789553227045,"version":"build-2803163510"},"reference-count":38,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011875","name":"Ministry of Science, Technology and Innovation of Colombia","doi-asserted-by":"publisher","award":["112721-148-2024"],"award-info":[{"award-number":["112721-148-2024"]}],"id":[{"id":"10.13039\/501100011875","id-type":"DOI","asserted-by":"publisher"}]},{"award":["112721-148-2024"],"award-info":[{"award-number":["112721-148-2024"]}],"id":[{"id":"https:\/\/ror.org\/03fd5ne08","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Fungi","JoF"],"abstract":"<jats:p>Background: Candida parapsilosis is an opportunistic yeast of increasing clinical importance, with fluconazole resistance rates rising globally and reaching concerning levels in clinical settings across several countries, including Colombia. However, the occurrence of antifungal-resistant Candida species in domestic water systems in the country remains largely unexplored. Methods: This cross-sectional study assessed the occurrence and antifungal susceptibility of Candida spp. in intradomiciliary water from 104 households in Villavicencio, Colombia, during two monitoring periods. Water samples were filtered, and yeast-like colonies were identified using MALDI-TOF mass spectrometry. Susceptibility to fluconazole, amphotericin B, and anidulafungin was determined using the CLSI broth microdilution method. The ERG11 gene was sequenced in the fluconazole-resistant isolate. Results: C. parapsilosis was recovered from 16 of 104 households (15.4%), yielding 22 isolates distributed across six communes. Most isolates (72.7%) were obtained from household water storage tanks. One isolate was resistant to fluconazole (MIC = 8 \u00b5g\/mL) and harbored a nonsynonymous R398I substitution in ERG11. Conclusions: To our knowledge, this is the first report of C. parapsilosis, including a fluconazole-resistant isolate carrying an ERG11 substitution, recovered from domestic water in Colombia. These findings suggest that household water storage tanks may serve as environmental reservoirs for this opportunistic yeast. The implications for human exposure remain to be determined and highlight the need for integrated One Health surveillance.<\/jats:p>","DOI":"10.3390\/jof12090694","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T09:06:37Z","timestamp":1789549597000},"page":"694","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["First Isolation of Candida parapsilosis from Water-Related Domestic Environments in Colombia: A Public Health Concern?"],"prefix":"10.3390","volume":"12","author":[{"given":"Norida","family":"V\u00e9lez","sequence":"first","affiliation":[{"name":"Grupo de Investigaci\u00f3n en Biotecnolog\u00eda y Toxicolog\u00eda Acu\u00e1tica y Ambiental\u2014BioTox, Escuela de Ciencias Animales, Facultad de Ciencias Agropecuarias y Recursos Naturales, Universidad de los Llanos, Villavicencio 500017, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"funding-acquisition","vocabulary":"credit"},{"role":"visualization","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"software","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"project-administration","vocabulary":"credit"}]},{"given":"Valentina","family":"Valencia","sequence":"additional","affiliation":[{"name":"Grupo de Investigaci\u00f3n en Biotecnolog\u00eda y Toxicolog\u00eda Acu\u00e1tica y Ambiental\u2014BioTox, Escuela de Ciencias Animales, Facultad de Ciencias Agropecuarias y Recursos Naturales, Universidad de los Llanos, Villavicencio 500017, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"investigation","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"visualization","vocabulary":"credit"}]},{"given":"Yohana M.","family":"Velasco-Santamar\u00eda","sequence":"additional","affiliation":[{"name":"Grupo de Investigaci\u00f3n en Biotecnolog\u00eda y Toxicolog\u00eda Acu\u00e1tica y Ambiental\u2014BioTox, Escuela de Ciencias Animales, Facultad de Ciencias Agropecuarias y Recursos Naturales, Universidad de los Llanos, Villavicencio 500017, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Escand\u00f3n","sequence":"additional","affiliation":[{"name":"Grupo de Microbiolog\u00eda, Instituto Nacional de Salud, Bogot\u00e1 111321, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Jos\u00e9","family":"Jim\u00e9nez-A","sequence":"additional","affiliation":[{"name":"Grupo de Investigaci\u00f3n Ceparium, Facultad de Ciencias de la Salud, Universidad Colegio Mayor de Cundinamarca, Bogot\u00e1 110311, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"visualization","vocabulary":"credit"},{"role":"software","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2129-1399","authenticated-orcid":false,"given":"Andr\u00e9s","family":"Ceballos-Garzon","sequence":"additional","affiliation":[{"name":"Studies in Translational Microbiology and Emerging Diseases (MICROS) Research Group, School of Medicine and Health Sciences, Universidad del Rosario, Bogot\u00e1 111221, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Caicedo-Bejarano, L.D., Osorio-Vanegas, L.S., Ram\u00edrez-Castrill\u00f3n, M., Castillo, J.E., Mart\u00ednez-Garay, C.A., and Ch\u00e1vez-Vivas, M. 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