{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:04:41Z","timestamp":1792789481038,"version":"4.5.0"},"reference-count":158,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,12,21]],"date-time":"2022-12-21T00:00:00Z","timestamp":1671580800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["FC 2015-02-834"],"award-info":[{"award-number":["FC 2015-02-834"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["Ciencia de Frontera 2019-6380"],"award-info":[{"award-number":["Ciencia de Frontera 2019-6380"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["CONACYT-M\u00e9xico"],"award-info":[{"award-number":["CONACYT-M\u00e9xico"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Red Tem\u00e1tica Glicociencia en Salud","award":["FC 2015-02-834"],"award-info":[{"award-number":["FC 2015-02-834"]}]},{"name":"Red Tem\u00e1tica Glicociencia en Salud","award":["Ciencia de Frontera 2019-6380"],"award-info":[{"award-number":["Ciencia de Frontera 2019-6380"]}]},{"name":"Red Tem\u00e1tica Glicociencia en Salud","award":["CONACYT-M\u00e9xico"],"award-info":[{"award-number":["CONACYT-M\u00e9xico"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JoF"],"abstract":"<jats:p>Fungal infections caused by Candida species have become a constant threat to public health, especially for immunocompromised patients, who are considered susceptible to this type of opportunistic infections. Candida albicans is known as the most common etiological agent of candidiasis; however, other species, such as Candida tropicalis, Candida parapsilosis, Nakaseomyces glabrata (previously known as Candida glabrata), Candida auris, Candida guilliermondii, and Pichia kudriavzevii (previously named as Candida krusei), have also gained great importance in recent years. The increasing frequency of the isolation of this non-albicans Candida species is associated with different factors, such as constant exposure to antifungal drugs, the use of catheters in hospitalized patients, cancer, age, and geographic distribution. The main concerns for the control of these pathogens include their ability to evade the mechanisms of action of different drugs, thus developing resistance to antifungal drugs, and it has also been shown that some of these species also manage to evade the host\u2019s immunity. These biological traits make candidiasis treatment a challenging task. In this review manuscript, a detailed update of the recent literature on the six most relevant non-albicans Candida species is provided, focusing on the immune response, evasion mechanisms, and new plant-derived compounds with antifungal properties.<\/jats:p>","DOI":"10.3390\/jof9010011","type":"journal-article","created":{"date-parts":[[2022,12,21]],"date-time":"2022-12-21T06:11:24Z","timestamp":1671603084000},"page":"11","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["Non-albicans Candida Species: Immune Response, Evasion Mechanisms, and New Plant-Derived Alternative Therapies"],"prefix":"10.3390","volume":"9","author":[{"given":"Manuela","family":"G\u00f3mez-Gaviria","sequence":"first","affiliation":[{"name":"Departamento de Biolog\u00eda, Divisi\u00f3n de Ciencias Naturales y Exactas, Campus Guanajuato, Universidad de Guanajuato, Noria Alta s\/n, col. Noria Alta, C.P., Guanajuato 36050, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uriel","family":"Ram\u00edrez-Sotelo","sequence":"additional","affiliation":[{"name":"Departamento de Biolog\u00eda, Divisi\u00f3n de Ciencias Naturales y Exactas, Campus Guanajuato, Universidad de Guanajuato, Noria Alta s\/n, col. Noria Alta, C.P., Guanajuato 36050, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6973-0595","authenticated-orcid":false,"given":"H\u00e9ctor M.","family":"Mora-Montes","sequence":"additional","affiliation":[{"name":"Departamento de Biolog\u00eda, Divisi\u00f3n de Ciencias Naturales y Exactas, Campus Guanajuato, Universidad de Guanajuato, Noria Alta s\/n, col. Noria Alta, C.P., Guanajuato 36050, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.idc.2021.03.007","article-title":"Candidemia and Invasive Candidiasis","volume":"35","author":"McCarty","year":"2021","journal-title":"Infect. Dis. Clin. N. Am."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1099\/jmm.0.045054-0","article-title":"Candida species: Current epidemiology, pathogenicity, biofilm formation, natural antifungal products and new therapeutic options","volume":"62","author":"Sardi","year":"2013","journal-title":"J. Med. Microbiol."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Mandras, N., Roana, J., Scalas, D., Del Re, S., Cavallo, L., Ghisetti, V., and Tullio, V. (2021). The Inhibition of Non-albicans Candida species and uncommon yeast pathogens by selected essential oils and their major compounds. Molecules, 26.","DOI":"10.3390\/molecules26164937"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/978-1-4939-6515-1_2","article-title":"The changing epidemiology of invasive fungal infections","volume":"1508","author":"Enoch","year":"2017","journal-title":"Methods Mol. Biol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.3389\/fmicb.2017.01927","article-title":"An update on Candida tropicalis based on basic and clinical approaches","volume":"8","author":"Chaves","year":"2017","journal-title":"Front. Microbiol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/s13756-021-00890-2","article-title":"Candida tropicalis distribution and drug resistance is correlated with ERG11 and UPC2 expression","volume":"10","author":"Wang","year":"2021","journal-title":"Antimicrob. Resist. Infect. Control."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.diagmicrobio.2016.02.009","article-title":"Antifungal susceptibility patterns of a global collection of fungal isolates: Results of the SENTRY Antifungal Surveillance Program (2013)","volume":"85","author":"Castanheira","year":"2016","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"464","DOI":"10.3389\/fmicb.2017.00464","article-title":"Notable increasing trend in azole non-susceptible Candida tropicalis causing invasive candidiasis in China (august 2009 to july 2014): Molecular epidemiology and clinical Azole consumption","volume":"8","author":"Fan","year":"2017","journal-title":"Front. Microbiol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1016\/j.cmi.2019.03.028","article-title":"Resistance of Candida to azoles and echinocandins worldwide","volume":"25","author":"Pristov","year":"2019","journal-title":"Clin. Microbiol. Infect."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"e00111-18","DOI":"10.1128\/CMR.00111-18","article-title":"Candida parapsilosis: From genes to the bedside","volume":"32","author":"Toth","year":"2019","journal-title":"Clin. Microbiol. Rev."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.1093\/jac\/dkw091","article-title":"Emergence of azole-resistant Candida parapsilosis causing bloodstream infection: Results from laboratory-based sentinel surveillance in South Africa","volume":"71","author":"Govender","year":"2016","journal-title":"J. Antimicrob. Chemother."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Pinhati, H.M., Casulari, L.A., Souza, A.C., Siqueira, R.A., Damasceno, C.M., and Colombo, A.L. (2016). Outbreak of candidemia caused by fluconazole resistant Candida parapsilosis strains in an intensive care unit. BMC Infect. Dis., 16.","DOI":"10.1186\/s12879-016-1767-9"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"e00547-18","DOI":"10.1128\/mSphere.00547-18","article-title":"Echinocandin-induced microevolution of Candida parapsilosis influences virulence and abiotic stress tolerance","volume":"3","author":"Papp","year":"2018","journal-title":"mSphere"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1093\/mmy\/myaa040","article-title":"Abundance interaction in Candida albicans and Candida glabrata mixed biofilms under diverse conditions","volume":"59","author":"Li","year":"2021","journal-title":"Med. Mycol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1111\/j.1574-6976.2011.00278.x","article-title":"Candida glabrata, Candida parapsilosis and Candida tropicalis: Biology, epidemiology, pathogenicity and antifungal resistance","volume":"36","author":"Silva","year":"2012","journal-title":"FEMS Microbiol. Rev."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1093\/cid\/cis697","article-title":"Changes in incidence and antifungal drug resistance in candidemia: Results from population-based laboratory surveillance in Atlanta and Baltimore, 2008\u20132011","volume":"55","author":"Cleveland","year":"2012","journal-title":"Clin. Infect. Dis."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"e00146-20","DOI":"10.1128\/IAI.00146-20","article-title":"Identification of Candida glabrata transcriptional regulators that govern stress resistance and virulence","volume":"89","author":"Filler","year":"2021","journal-title":"Infect. Immun."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Cleveland, A.A., Harrison, L.H., Farley, M.M., Hollick, R., Stein, B., Chiller, T.M., Lockhart, S.R., and Park, B.J. (2015). Declining incidence of candidemia and the shifting epidemiology of Candida resistance in two US metropolitan areas, 2008\u20132013: Results from population-based surveillance. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0120452"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"ofv163","DOI":"10.1093\/ofid\/ofv163","article-title":"Epidemiology and risk factors for echinocandin nonsusceptible Candida glabrata bloodstream infections: Data from a large multisite population-based candidemia surveillance program, 2008\u20132014","volume":"2","author":"Vallabhaneni","year":"2015","journal-title":"Open Forum Infect. Dis."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Mart\u00ednez-Herrera, E., Fr\u00edas-De-Le\u00f3n, M.G., Hern\u00e1ndez-Castro, R., Garc\u00eda-Salazar, E., Arenas, R., Ocharan-Hern\u00e1ndez, E., and Rodr\u00edguez-Cerdeira, C. (2021). Antifungal resistance in clinical isolates of Candida glabrata in Ibero-America. J. Fungi, 8.","DOI":"10.3390\/jof8010014"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.2147\/IDR.S247944","article-title":"Current aspects in the biology, pathogeny, and treatment of Candida krusei, a neglected fungal pathogen","volume":"13","year":"2020","journal-title":"Infect. Drug Resist."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1111\/j.1447-0756.2008.00817.x","article-title":"Clinical characteristics of vulvovaginal candidiasis and antifungal susceptibilities of Candida species isolates among patients in southern China from 2003 to 2006","volume":"34","author":"Fan","year":"2008","journal-title":"J. Obstet. Gynaecol. Res."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"3347","DOI":"10.1128\/AAC.01480-08","article-title":"Anidulafungin is fungicidal and exerts a variety of postantifungal effects against Candida albicans, C. glabrata, C. parapsilosis, and C. krusei isolates","volume":"53","author":"Nguyen","year":"2009","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"6975","DOI":"10.1128\/AAC.01005-15","article-title":"Rapid development of Candida krusei echinocandin resistance during caspofungin therapy","volume":"59","author":"Forastiero","year":"2015","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"2717","DOI":"10.3389\/fmicb.2018.02717","article-title":"Genetic differentiation, diversity, and drug susceptibility of Candida krusei","volume":"9","author":"Gong","year":"2018","journal-title":"Front. Microbiol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1007\/s11046-020-00485-2","article-title":"Clinical characteristics and outcomes of candidemia caused by Meyerozyma guilliermondii complex in cancer patients undergoing surgery","volume":"185","author":"Chen","year":"2020","journal-title":"Mycopathologia"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"199","DOI":"10.2147\/IDR.S80677","article-title":"Retrospective analysis of mortality and Candida isolates of 75 patients with candidemia: A single hospital experience","volume":"8","author":"Hirano","year":"2015","journal-title":"Infect. Drug Resist."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"821","DOI":"10.2147\/IDR.S156633","article-title":"Epidemiology, practice patterns, and prognostic factors for candidemia; and characteristics of fourteen patients with breakthrough Candida bloodstream infections: A single tertiary hospital experience in Japan","volume":"11","author":"Hirano","year":"2018","journal-title":"Infect. Drug Resist."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"e01791-16","DOI":"10.1128\/AAC.01791-16","article-title":"Clinical and microbiological characteristics of breakthrough candidemia in allogeneic hematopoietic stem cell transplant recipients in a japanese hospital","volume":"61","author":"Kimura","year":"2017","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1111\/j.1439-0507.2010.01960.x","article-title":"What do we know about Candida guilliermondii? A voyage throughout past and current literature about this emerging yeast","volume":"54","author":"Savini","year":"2011","journal-title":"Mycoses"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1348-0421.2008.00083.x","article-title":"Candida auris sp. nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese hospital","volume":"53","author":"Satoh","year":"2009","journal-title":"Microbiol. Immunol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"e01588-17","DOI":"10.1128\/JCM.01588-17","article-title":"Candida auris: An emerging fungal pathogen","volume":"56","author":"Spivak","year":"2018","journal-title":"J. Clin. Microbiol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.mycmed.2016.04.004","article-title":"Anti-Candida activity of geraniol involves disruption of cell membrane integrity and function","volume":"26","author":"Sharma","year":"2016","journal-title":"J. Mycol. Med."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"e0040621","DOI":"10.1128\/mSphere.00406-21","article-title":"Candida auris cell wall mannosylation contributes to neutrophil evasion through pathways divergent from Candida albicans and Candida glabrata","volume":"6","author":"Horton","year":"2021","journal-title":"mSphere"},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Sabino, R., Ver\u00edssimo, C., Pereira, \u00c1.A., and Antunes, F. (2020). Candida auris, an agent of hospital-associated outbreaks: Which challenging issues do we need to have in mind?. Microorganisms, 8.","DOI":"10.3390\/microorganisms8020181"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s13756-016-0132-5","article-title":"First hospital outbreak of the globally emerging Candida auris in a European hospital","volume":"5","author":"Schelenz","year":"2016","journal-title":"Antimicrob. Resist. Infect. Control."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"903","DOI":"10.2147\/IDR.S170337","article-title":"Current trends to control fungal pathogens: Exploiting our knowledge in the host-pathogen interaction","volume":"11","year":"2018","journal-title":"Infect. Drug Resist."},{"key":"ref_38","doi-asserted-by":"crossref","unstructured":"Czechowicz, P., Nowicka, J., and Go\u015bciniak, G. (2022). Virulence factors of Candida spp. and host immune response important in the pathogenesis of vulvovaginal candidiasis. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23115895"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1093\/mmy\/myab053","article-title":"Opportunistic yeast pathogen Candida spp.: Secreted and membrane-bound virulence factors","volume":"59","author":"Lim","year":"2021","journal-title":"Med. Mycol."},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Talapko, J., Juzba\u0161i\u0107, M., Matijevi\u0107, T., Pustijanac, E., Beki\u0107, S., Kotris, I., and \u0160krlec, I. (2021). Candida albicans-the virulence factors and clinical manifestations of infection. J. Fungi, 7.","DOI":"10.3390\/jof7020079"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s12281-012-0109-7","article-title":"Role of the fungal cell wall in pathogenesis and antifungal resistance","volume":"6","year":"2012","journal-title":"Curr. Fungal Infect. Rep."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"783","DOI":"10.2147\/IDR.S197531","article-title":"Differential recognition of Candida tropicalis, Candida guilliermondii, Candida krusei, and Candida auris by human innate immune cells","volume":"12","author":"Franco","year":"2019","journal-title":"Infect. Drug Resist."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1038\/nrmicro1815","article-title":"An integrated model of the recognition of Candida albicans by the innate immune system","volume":"6","author":"Netea","year":"2008","journal-title":"Nat. Rev. Microbiol."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"5121","DOI":"10.2147\/IDR.S383785","article-title":"Candida lusitaniae: Biology, pathogenicity, virulence factors, diagnosis, and treatment","volume":"15","year":"2022","journal-title":"Infect. Drug Resist."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"fov042","DOI":"10.1093\/femsyr\/fov042","article-title":"Intracellular survival of Candida glabrata in macrophages: Immune evasion and persistence","volume":"15","author":"Kasper","year":"2015","journal-title":"FEMS Yeast Res."},{"key":"ref_46","first-page":"306","article-title":"Role of protein glycosylation in Candida parapsilosis cell wall integrity and host interaction","volume":"7","author":"Csonka","year":"2016","journal-title":"Front. Microbiol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1080\/00362178585380541","article-title":"In-vitro killing of Candida species by murine immunoeffectors and its relationship to the experimental pathogenicity","volume":"23","author":"Vecchiarelli","year":"1985","journal-title":"Sabouraudia"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1002\/jlb.57.4.651","article-title":"Effects of granulocyte colony-stimulating factor and interferon-\u03b3 on antifungal activity of human polymorphonuclear neutrophils against pseudohyphae of different medically important Candida species","volume":"57","author":"Roilides","year":"1995","journal-title":"J. Leuk. Biol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1099\/00222615-42-4-291","article-title":"Various Candida and Torulopsis species differ in their ability to induce the production of C3, factor B and granulocyte-macrophage colony-stimulating factor (GM-CSF) in human monocyte cultures","volume":"42","author":"Abrahamsen","year":"1995","journal-title":"J. Med. Microbiol."},{"key":"ref_50","first-page":"1527","article-title":"Members of the Candida parapsilosis complex and Candida albicans are differentially recognized by human peripheral blood mononuclear cells","volume":"6","author":"Csonka","year":"2015","journal-title":"Front. Microbiol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"940383","DOI":"10.1155\/2010\/940383","article-title":"Normal human gingival epithelial cells sense C. parapsilosis by toll-like receptors and module its pathogenesis through antimicrobial peptides and proinflammatory cytokines","volume":"2010","author":"Bahri","year":"2010","journal-title":"Mediat. Inflamm."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"43129","DOI":"10.1038\/srep43129","article-title":"Specific pathways mediating inflammasome activation by Candida parapsilosis","volume":"7","author":"Zajta","year":"2017","journal-title":"Sci. Rep."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1111\/cmi.12103","article-title":"The role of galectin-3 in phagocytosis of Candida albicans and Candida parapsilosis by human neutrophils","volume":"15","author":"Linden","year":"2013","journal-title":"Cell. Microbiol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1093\/infdis\/jit188","article-title":"Candida albicans and Candida parapsilosis induce different T-cell responses in human peripheral blood mononuclear cells","volume":"208","author":"Csonka","year":"2013","journal-title":"J. Infect. Dis."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1128\/IAI.01189-13","article-title":"Role of dectin-2 for host defense against systemic infection with Candida glabrata","volume":"82","author":"Ifrim","year":"2014","journal-title":"Infect. Immun."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1002\/eji.201041252","article-title":"The role of Syk\/CARD9 coupled C-type lectins in antifungal immunity","volume":"41","author":"Drummond","year":"2011","journal-title":"Eur. J. Immunol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"3072","DOI":"10.4049\/jimmunol.1003730","article-title":"The facultative intracellular pathogen Candida glabrata subverts macrophage cytokine production and phagolysosome maturation","volume":"187","author":"Seider","year":"2011","journal-title":"J. Immunol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S0304-4165(98)00134-2","article-title":"Mannosylphosphate transfer to yeast mannan","volume":"1426","author":"Jigami","year":"1999","journal-title":"Biochim. Biophys. Acta"},{"key":"ref_59","first-page":"foy053","article-title":"Role of protein phosphomannosylation in the Candida tropicalis-macrophage interaction","volume":"18","author":"Franco","year":"2018","journal-title":"FEMS Yeast Res."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"2156","DOI":"10.3389\/fmicb.2017.02156","article-title":"Phosphomannosylation and the functional analysis of the extended Candida albicans MNN4-like gene family","volume":"8","author":"Jin","year":"2017","journal-title":"Front. Microbiol."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"5185","DOI":"10.1128\/IAI.70.9.5185-5192.2002","article-title":"The yeast Candida albicans binds complement regulators factor H and FHL-1","volume":"70","author":"Meri","year":"2002","journal-title":"Infect. Immun."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1038\/s41564-020-0780-3","article-title":"Transcriptional and functional insights into the host immune response against the emerging fungal pathogen Candida auris","volume":"5","author":"Bruno","year":"2020","journal-title":"Nat. Microbiol."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"e01403-18","DOI":"10.1128\/mBio.01403-18","article-title":"Emerging fungal pathogen Candida auris evades neutrophil attack","volume":"9","author":"Johnson","year":"2018","journal-title":"mBio"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/S1369-5274(02)00342-9","article-title":"Interactions of fungi with phagocytes","volume":"5","author":"Mansour","year":"2002","journal-title":"Curr. Opin. Microbiol."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1111\/j.1462-5822.2005.00659.x","article-title":"Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms","volume":"8","author":"Urban","year":"2006","journal-title":"Cell. Microbiol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"3553","DOI":"10.1038\/s41467-022-31201-x","article-title":"Innate immune responses against the fungal pathogen Candida auris","volume":"13","author":"Wang","year":"2022","journal-title":"Nat. Commun."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1038\/sj.emboj.7600594","article-title":"Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments","volume":"24","author":"Gantner","year":"2005","journal-title":"Embo J."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1086\/523110","article-title":"Immune recognition of Candida albicans beta-glucan by dectin-1","volume":"196","author":"Gow","year":"2007","journal-title":"J. Infect. Dis."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1002\/eji.200838543","article-title":"Reciprocal regulation of IL-23 and IL-12 following co-activation of Dectin-1 and TLR signaling pathways","volume":"39","author":"Dennehy","year":"2009","journal-title":"Eur. J. Immunol."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1084\/jem.20021787","article-title":"Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2","volume":"197","author":"Gantner","year":"2003","journal-title":"J. Exp. Med."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s00430-013-0288-z","article-title":"Thriving within the host: Candida spp. interactions with phagocytic cells","volume":"202","author":"Kasper","year":"2013","journal-title":"Med. Microbiol. Immunol."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1111\/j.1462-5822.2004.00439.x","article-title":"Candida albicans proteinases and host\/pathogen interactions","volume":"6","author":"Naglik","year":"2004","journal-title":"Cell. Microbiol."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"7628","DOI":"10.1073\/pnas.0611195104","article-title":"A family of glycosylphosphatidylinositol-linked aspartyl proteases is required for virulence of Candida glabrata","volume":"104","author":"Kaur","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1093\/infdis\/jir873","article-title":"The identification of gene duplication and the role of secreted aspartyl proteinase 1 in Candida parapsilosis virulence","volume":"205","author":"Nosanchuk","year":"2012","journal-title":"J. Infect. Dis."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1128\/EC.3.5.1076-1087.2004","article-title":"Transcriptional response of Candida albicans upon internalization by macrophages","volume":"3","author":"Lorenz","year":"2004","journal-title":"Eukaryot. Cell."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"e00832-16","DOI":"10.1128\/IAI.00832-16","article-title":"Phagosomal neutralization by the fungal pathogen Candida albicans induces macrophage pyroptosis","volume":"85","author":"Vylkova","year":"2017","journal-title":"Infect. Immun."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.febslet.2010.12.006","article-title":"Regulation of Candida glabrata oxidative stress resistance is adapted to host environment","volume":"585","author":"Roetzer","year":"2011","journal-title":"FEBS Lett."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.1128\/IAI.00044-11","article-title":"The interaction between Candida krusei and murine macrophages results in multiple outcomes, including intracellular survival and escape from killing","volume":"79","author":"Zaragoza","year":"2011","journal-title":"Infect. Immun."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1046\/j.1365-2958.2003.03747.x","article-title":"Nitrogen metabolism and virulence of Candida albicans require the GATA-type transcriptional activator encoded by GAT1","volume":"50","author":"Limjindaporn","year":"2003","journal-title":"Mol. Microbiol."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"131","DOI":"10.3389\/fcimb.2016.00131","article-title":"Transcriptional control of drug resistance, virulence and immune system evasion in pathogenic fungi: A cross-species comparison","volume":"6","author":"Pais","year":"2016","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"2482","DOI":"10.1172\/JCI63239","article-title":"Fungal antioxidant pathways promote survival against neutrophils during infection","volume":"122","author":"Leal","year":"2012","journal-title":"J. Clin. Investig."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"2290","DOI":"10.1128\/EC.00267-07","article-title":"The Aspergillus fumigatus transcriptional regulator AfYap1 represents the major regulator for defense against reactive oxygen intermediates but is dispensable for pathogenicity in an intranasal mouse infection model","volume":"6","author":"Lessing","year":"2007","journal-title":"Eukaryot. Cell."},{"key":"ref_83","doi-asserted-by":"crossref","unstructured":"Homann, O.R., Dea, J., Noble, S.M., and Johnson, A.D. (2009). A phenotypic profile of the Candida albicans regulatory network. PLoS Genet., 5.","DOI":"10.1371\/journal.pgen.1000783"},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s11046-009-9233-5","article-title":"Skn7p is involved in oxidative stress response and virulence of Candida glabrata","volume":"169","author":"Saijo","year":"2010","journal-title":"Mycopathologia"},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1128\/EC.00011-08","article-title":"High resistance to oxidative stress in the fungal pathogen Candida glabrata is mediated by a single catalase, Cta1p, and is controlled by the transcription factors Yap1p, Skn7p, Msn2p, and Msn4p","volume":"7","year":"2008","journal-title":"Eukaryot. Cell."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1128\/EC.3.3.715-723.2004","article-title":"Inducible defense mechanism against nitric oxide in Candida albicans","volume":"3","author":"Ullmann","year":"2004","journal-title":"Eukaryot. Cell."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1128\/EC.00240-07","article-title":"CTA4 Transcription factor mediates induction of nitrosative stress response in Candida albicans","volume":"7","author":"Chiranand","year":"2008","journal-title":"Eukaryot. Cell."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1111\/mmi.12983","article-title":"Yap7 is a transcriptional repressor of nitric oxide oxidase in yeasts, which arose from neofunctionalization after whole genome duplication","volume":"96","author":"Merhej","year":"2015","journal-title":"Mol. Microbiol."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1099\/mic.0.000312","article-title":"Gln3 is a main regulator of nitrogen assimilation in Candida glabrata","volume":"162","year":"2016","journal-title":"Microbiology"},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1111\/j.1365-2958.2005.04557.x","article-title":"Granulocytes govern the transcriptional response, morphology and proliferation of Candida albicans in human blood","volume":"56","author":"Fradin","year":"2005","journal-title":"Mol. Microbiol."},{"key":"ref_91","first-page":"3193","article-title":"THR1 mediates GCN4 and CDC4 to link morphogenesis with nutrient sensing and the stress response in Candida albicans","volume":"42","author":"Lee","year":"2018","journal-title":"Int. J. Mol. Med."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1128\/IAI.01452-08","article-title":"Arginine-induced germ tube formation in Candida albicans is essential for escape from murine macrophage line RAW 264.7","volume":"77","author":"Ghosh","year":"2009","journal-title":"Infect. Immun."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"e13197","DOI":"10.1111\/cmi.13197","article-title":"Fungal biotin homeostasis is essential for immune evasion after macrophage phagocytosis and virulence","volume":"22","author":"Sprenger","year":"2020","journal-title":"Cell. Microbiol."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1038\/ni.2987","article-title":"Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens","volume":"15","author":"Branzk","year":"2014","journal-title":"Nat. Immunol."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"e00189-16","DOI":"10.1128\/mSphere.00189-16","article-title":"Comparative pathogenicity of United Kingdom isolates of the emerging pathogen Candida auris and other key pathogenic Candida species","volume":"1","author":"Borman","year":"2016","journal-title":"mSphere"},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"e00371-20","DOI":"10.1128\/mSphere.00371-20","article-title":"Candida auris phenotypic heterogeneity determines pathogenicity in vitro","volume":"5","author":"Brown","year":"2020","journal-title":"mSphere"},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"165rv113","DOI":"10.1126\/scitranslmed.3004404","article-title":"Hidden killers: Human fungal infections","volume":"4","author":"Brown","year":"2012","journal-title":"Sci. Transl. Med."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1517\/17460441.2013.807245","article-title":"Candidiasis drug discovery and development: New approaches targeting virulence for discovering and identifying new drugs","volume":"8","author":"Pierce","year":"2013","journal-title":"Expert Opin. Drug Discov."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1128\/CMR.00029-06","article-title":"Epidemiology of invasive candidiasis: A persistent public health problem","volume":"20","author":"Pfaller","year":"2007","journal-title":"Clin. Microbiol. Rev."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1099\/00222615-44-6-399","article-title":"Molecular genetic approaches to identification, epidemiology and taxonomy of non-albicans Candida species","volume":"44","author":"Sullivan","year":"1996","journal-title":"J. Med. Microbiol."},{"key":"ref_101","doi-asserted-by":"crossref","unstructured":"Guevara-Lora, I., Bras, G., Karkowska-Kuleta, J., Gonz\u00e1lez-Gonz\u00e1lez, M., Ceballos, K., Sidlo, W., and Rapala-Kozik, M. (2020). Plant-derived substances in the fight against infections caused by Candida species. Int. J. Mol. Sci., 21.","DOI":"10.3390\/ijms21176131"},{"key":"ref_102","doi-asserted-by":"crossref","unstructured":"Pedroso, R.D.S., Balbino, B.L., Andrade, G., Dias, M., Alvarenga, T.A., Pedroso, R.C.N., Pimenta, L.P., Lucarini, R., Pauletti, P.M., and Janu\u00e1rio, A.H. (2019). In vitro and in vivo anti-Candida spp. activity of plant-derived products. Plants, 8.","DOI":"10.3390\/plants8110494"},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/1751-7915.12123","article-title":"Discovering new bioactive molecules from microbial sources","volume":"7","author":"Monciardini","year":"2014","journal-title":"Microb. Biotechnol."},{"key":"ref_104","doi-asserted-by":"crossref","unstructured":"Soliman, S.S.M., Semreen, M.H., El-Keblawy, A.A., Abdullah, A., Uppuluri, P., and Ibrahim, A.S. (2017). Assessment of herbal drugs for promising anti-Candida activity. BMC Complement. Altern. Med., 17.","DOI":"10.1186\/s12906-017-1760-x"},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.3389\/fmicb.2018.01351","article-title":"Candida infections and therapeutic strategies: Mechanisms of action for traditional and alternative agents","volume":"9","author":"Vasconcelos","year":"2018","journal-title":"Front. Microbiol."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1099\/jmm.0.036988-0","article-title":"Correlation of the chemical composition of essential oils from Origanum vulgare subsp. virens with their in vitro activity against pathogenic yeasts and filamentous fungi","volume":"61","author":"Silva","year":"2012","journal-title":"J. Med. Microbiol."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"567","DOI":"10.11622\/smedj.2015153","article-title":"Comparison of the therapeutic effects of Garcin(\u00ae) and fluconazole on Candida vaginitis","volume":"56","author":"Ebrahimy","year":"2015","journal-title":"Singap. Med. J."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.mycmed.2015.06.003","article-title":"In vitro activity of essential oils extracted from condiments against fluconazole-resistant and -sensitive Candida glabrata","volume":"25","author":"Soares","year":"2015","journal-title":"J. Mycol. Med."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.3389\/fmicb.2015.01420","article-title":"Potential use of phenolic acids as anti-Candida agents: A review","volume":"6","author":"Teodoro","year":"2015","journal-title":"Front. Microbiol."},{"key":"ref_110","doi-asserted-by":"crossref","unstructured":"Aldholmi, M., Marchand, P., Ourliac-Garnier, I., Le Pape, P., and Ganesan, A. (2019). A decade of antifungal leads from natural products: 2010\u20132019. Pharmaceuticals, 12.","DOI":"10.3390\/ph12040182"},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"e1900434","DOI":"10.1002\/cbdv.201900434","article-title":"Natural monoterpenes: Much more than only a scent","volume":"16","author":"Kasprzak","year":"2019","journal-title":"Chem. Biodivers."},{"key":"ref_112","doi-asserted-by":"crossref","unstructured":"Taveira, G.B., Carvalho, A.O., Rodrigues, R., Trindade, F.G., Da Cunha, M., and Gomes, V.M. (2016). Thionin-like peptide from Capsicum annuum fruits: Mechanism of action and synergism with fluconazole against Candida species. BMC Microbiol., 16.","DOI":"10.1186\/s12866-016-0626-6"},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1002\/bip.22351","article-title":"Thionin-like peptides from Capsicum annuum fruits with high activity against human pathogenic bacteria and yeasts","volume":"102","author":"Taveira","year":"2014","journal-title":"Biopolymers"},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"183092","DOI":"10.1016\/j.bbamem.2019.183092","article-title":"RcAlb-PepII, a synthetic small peptide bioinspired in the 2S albumin from the seed cake of Ricinus communis, is a potent antimicrobial agent against Klebsiella pneumoniae and Candida parapsilosis","volume":"1862","author":"Dias","year":"2020","journal-title":"Biochim. Biophys. Acta Biomembr."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1016\/j.peptides.2011.06.020","article-title":"Identification of an antifungal peptide from Trapa natans fruits with inhibitory effects on Candida tropicalis biofilm formation","volume":"32","author":"Mandal","year":"2011","journal-title":"Peptides"},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1007\/s12602-020-09739-3","article-title":"Potent anti-Candida fraction isolated from Capsicum chinense fruits contains an antimicrobial peptide that is similar to plant defensin and is able to inhibit the activity of different \u03b1-amylase enzymes","volume":"13","author":"Aguieiras","year":"2021","journal-title":"Probiotics Antimicrob. Proteins"},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"611","DOI":"10.3389\/fmicb.2016.00611","article-title":"A trypsin inhibitor from Tecoma stans leaves inhibits growth and promotes ATP depletion and lipid peroxidation in Candida albicans and Candida krusei","volume":"7","author":"Patriota","year":"2016","journal-title":"Front. Microbiol."},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.ijbiomac.2017.12.039","article-title":"PgTeL, the lectin found in Punica granatum juice, is an antifungal agent against Candida albicans and Candida krusei","volume":"108","author":"Gomes","year":"2018","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"2090","DOI":"10.1016\/j.peptides.2008.08.008","article-title":"Isolation, characterization and cloning of a cDNA encoding a new antifungal defensin from Phaseolus vulgaris L. seeds","volume":"29","author":"Games","year":"2008","journal-title":"Peptides"},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1007\/s00284-010-9847-3","article-title":"Antifungal activity of PvD1 defensin involves plasma membrane permeabilization, inhibition of medium acidification, and induction of ROS in fungi cells","volume":"62","author":"Mello","year":"2011","journal-title":"Curr. Microbiol."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"139","DOI":"10.2217\/fmb.13.147","article-title":"Antifungal activity of phenolic compounds identified in flowers from North Eastern Portugal against Candida species","volume":"9","author":"Alves","year":"2014","journal-title":"Future Microbiol."},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.fitote.2009.05.006","article-title":"Phytochemical and antifungal studies on Terminalia mollis and Terminalia brachystemma","volume":"80","author":"Liu","year":"2009","journal-title":"Fitoterapia"},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"917","DOI":"10.2217\/fmb.15.20","article-title":"Antifungal activity of extracts and isolated compounds from Buchenavia tomentosa on Candida albicans and non-albicans","volume":"10","author":"Teodoro","year":"2015","journal-title":"Future Microbiol."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"396","DOI":"10.3109\/13880209.2010.519390","article-title":"Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids","volume":"49","author":"Kartal","year":"2011","journal-title":"Pharm. Biol."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1111\/j.1472-765X.2011.03032.x","article-title":"Enhanced activity of antifungal drugs using natural phenolics against yeast strains of Candida and Cryptococcus","volume":"52","author":"Faria","year":"2011","journal-title":"Lett. Appl. Microbiol."},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"12201","DOI":"10.1021\/acsomega.8b01856","article-title":"Effectiveness of phytoactive molecules on transcriptional expression, biofilm matrix, and cell wall components of Candida glabrata and Its clinical isolates","volume":"3","author":"Gupta","year":"2018","journal-title":"ACS Omega"},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.colsurfb.2003.11.007","article-title":"Surface activity of thymol: Implications for an eventual pharmacological activity","volume":"34","author":"Turina","year":"2004","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.3389\/fmicb.2016.01516","article-title":"Antiproliferation of berberine in combination with fluconazole from the perspectives of reactive oxygen species, ergosterol and drug efflux in a fluconazole-resistant Candida tropicalis Isolate","volume":"7","author":"Shao","year":"2016","journal-title":"Front. Microbiol."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.fitote.2017.01.011","article-title":"Epidihydropinidine, the main piperidine alkaloid compound of Norway spruce (Picea abies) shows promising antibacterial and anti-Candida activity","volume":"117","author":"Fyhrquist","year":"2017","journal-title":"Fitoterapia"},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.clim.2009.12.004","article-title":"Antimicrobial peptides: General overview and clinical implications in human health and disease","volume":"135","year":"2010","journal-title":"Clin. Immunol."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1007\/s00018-005-5574-5","article-title":"Plant thionins\u2014The structural perspective","volume":"63","author":"Stec","year":"2006","journal-title":"Cell. Mol. Life Sci."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.bbamem.2015.12.015","article-title":"Synthetic antibiofilm peptides","volume":"1858","author":"Cardoso","year":"2016","journal-title":"Biochim. Biophys. Acta"},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.jmii.2016.12.005","article-title":"Antimicrobial peptides as potential anti-biofilm agents against multidrug-resistant bacteria","volume":"50","author":"Chung","year":"2017","journal-title":"J. Microbiol. Immunol. Infect."},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1113\/expphysiol.1997.sp004024","article-title":"Oxidative stress: Oxidants and antioxidants","volume":"82","author":"Sies","year":"1997","journal-title":"Exp. Physiol."},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.toxicon.2007.05.005","article-title":"Isolation and characterization of novel peptides from chilli pepper seeds: Antimicrobial activities against pathogenic yeasts","volume":"50","author":"Ribeiro","year":"2007","journal-title":"Toxicon"},{"key":"ref_136","doi-asserted-by":"crossref","unstructured":"Perez-Rodriguez, A., Eraso, E., Quind\u00f3s, G., and Mateo, E. (2022). Antimicrobial peptides with anti-Candida activity. Int. J. Mol. Sci., 23.","DOI":"10.3390\/ijms23169264"},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.indcrop.2015.05.067","article-title":"Activity of phenolic compounds from plant origin against Candida species","volume":"74","author":"Martins","year":"2015","journal-title":"Ind. Crops Prod."},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1139\/W09-058","article-title":"The effects of tea polyphenols on Candida albicans: Inhibition of biofilm formation and proteasome inactivation","volume":"55","author":"Evensen","year":"2009","journal-title":"Can. J. Microbiol."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.ijantimicag.2014.05.017","article-title":"Utilising polyphenols for the clinical management of Candida albicans biofilms","volume":"44","author":"Shahzad","year":"2014","journal-title":"Int. J. Antimicrob. Agents"},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.fitote.2011.12.023","article-title":"In vitro antifungal activities of longan (Dimocarpus longan Lour.) seed extract","volume":"83","author":"Rangkadilok","year":"2012","journal-title":"Fitoterapia"},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.jep.2013.04.043","article-title":"Antimicrobial activity of Schinus lentiscifolius (Anacardiaceae)","volume":"148","author":"Gehrke","year":"2013","journal-title":"J. Ethnopharmacol."},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1021\/acs.jnatprod.8b01025","article-title":"Bioassay-guided isolation of fungistatic compounds from Mimosa caesalpiniifolia leaves","volume":"82","author":"Simonet","year":"2019","journal-title":"J. Nat. Prod."},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1080\/14786419.2014.1000892","article-title":"Antifungal activity of extracts from Cynomorium coccineum growing wild in Sardinia island (Italy)","volume":"29","author":"Piras","year":"2015","journal-title":"Nat. Prod. Res."},{"key":"ref_144","doi-asserted-by":"crossref","unstructured":"Correia, A.F., Silveira, D., Fonseca-Bazzo, Y.M., Magalh\u00e3es, P.O., Fagg, C.W., da Silva, E.C., Gomes, S.M., Gandolfi, L., Pratesi, R., and de Medeiros N\u00f3brega, Y.K. (2016). Activity of crude extracts from Brazilian cerrado plants against clinically relevant Candida species. BMC Complement. Altern. Med., 16.","DOI":"10.1186\/s12906-016-1164-3"},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1038\/s41598-020-58203-3","article-title":"Improved efficacy of antifungal drugs in combination with monoterpene phenols against Candida auris","volume":"10","author":"Shaban","year":"2020","journal-title":"Sci. Rep."},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/j.phymed.2011.03.008","article-title":"Terpenoids inhibit Candida albicans growth by affecting membrane integrity and arrest of cell cycle","volume":"18","author":"Zore","year":"2011","journal-title":"Phytomedicine"},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.ijantimicag.2008.01.028","article-title":"In vitro activity of terpenes against Candida biofilms","volume":"31","author":"Dalleau","year":"2008","journal-title":"Int. J. Antimicrob. Agents"},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"14418","DOI":"10.3390\/molecules171214418","article-title":"Antifungal activity of Thymus vulgaris L. essential oil and its constituent phytochemicals against Rhizopus oryzae: Interaction with ergosterol","volume":"17","author":"Lima","year":"2012","journal-title":"Molecules"},{"key":"ref_149","doi-asserted-by":"crossref","unstructured":"de Castro, R.D., de Souza, T.M., Bezerra, L.M., Ferreira, G.L., Costa, E.M., and Cavalcanti, A.L. (2015). Antifungal activity and mode of action of thymol and its synergism with nystatin against Candida species involved with infections in the oral cavity: An in vitro study. BMC Complement. Altern. Med., 15.","DOI":"10.1186\/s12906-015-0947-2"},{"key":"ref_150","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1080\/08927014.2020.1759559","article-title":"Antifungal evaluation of traditional herbal monomers and their potential for inducing cell wall remodeling in Candida albicans and Candida auris","volume":"36","author":"Liu","year":"2020","journal-title":"Biofouling"},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.fct.2007.09.106","article-title":"Biological effects of essential oils--a review","volume":"46","author":"Bakkali","year":"2008","journal-title":"Food Chem. Toxicol."},{"key":"ref_152","doi-asserted-by":"crossref","unstructured":"Serra, E., Hidalgo-Bastida, L.A., Verran, J., Williams, D., and Malic, S. (2018). Antifungal activity of commercial essential oils and biocides against Candida albicans. Pathogens, 7.","DOI":"10.3390\/pathogens7010015"},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s11046-011-9448-0","article-title":"Anticandidal efficacy of cinnamon oil against planktonic and biofilm cultures of Candida parapsilosis and Candida orthopsilosis","volume":"172","author":"Pires","year":"2011","journal-title":"Mycopathologia"},{"key":"ref_154","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.mycmed.2018.02.012","article-title":"Effects of patchouli and cinnamon essential oils on biofilm and hyphae formation by Candida species","volume":"28","author":"Rubini","year":"2018","journal-title":"J. Mycol. Med."},{"key":"ref_155","doi-asserted-by":"crossref","unstructured":"Zapata-Zapata, C., Loaiza-Oliva, M., Mart\u00ednez-Pab\u00f3n, M.C., Stashenko, E.E., and Mesa-Arango, A.C. (2022). In vitro activity of essential oils distilled from colombian plants against Candida auris and other Candida species with different antifungal susceptibility profiles. Molecules, 27.","DOI":"10.3390\/molecules27206837"},{"key":"ref_156","doi-asserted-by":"crossref","unstructured":"Baldim, I., Paziani, M.H., Grizante Bari\u00e3o, P.H., Kress, M., and Oliveira, W.P. (2022). Nanostructured lipid carriers loaded with Lippia sidoides essential oil as a strategy to combat the multidrug-resistant Candida auris. Pharmaceutics, 14.","DOI":"10.3390\/pharmaceutics14010180"},{"key":"ref_157","doi-asserted-by":"crossref","unstructured":"Horn, C., and Vediyappan, G. (2021). Anticapsular and antifungal activity of \u03b1-cyperone. Antibiotics, 10.","DOI":"10.3390\/antibiotics10010051"},{"key":"ref_158","doi-asserted-by":"crossref","first-page":"8911","DOI":"10.1007\/s00253-020-10829-z","article-title":"In vitro antifungal activity of Cinnamomum zeylanicum bark and leaf essential oils against Candida albicans and Candida auris","volume":"104","author":"Tran","year":"2020","journal-title":"Appl. Microbiol. Biotechnol."}],"container-title":["Journal of Fungi"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2309-608X\/9\/1\/11\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:45:22Z","timestamp":1760147122000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2309-608X\/9\/1\/11"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,21]]},"references-count":158,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,1]]}},"alternative-id":["jof9010011"],"URL":"https:\/\/doi.org\/10.3390\/jof9010011","relation":{},"ISSN":["2309-608X"],"issn-type":[{"value":"2309-608X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,21]]}}}