{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T20:22:50Z","timestamp":1793305370540,"version":"4.5.0"},"reference-count":34,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2023,6,29]],"date-time":"2023-06-29T00:00:00Z","timestamp":1687996800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JoF"],"abstract":"<jats:p>Candida auris is an emerging pathogen considered to be critical in the World Health Organization fungal organisms list. The study aims to determine the mortality and hospital stays attributed to Candida auris (C. auris) compared to other Candida species in adult patients with candidemia. A retrospective cohort of adults with candidemia was examined from seven centres in Colombia between 2016 and 2021. The primary outcome was 30-day mortality, and the secondary outcome was the length of hospital stay among survivors. Adjustment of the confounding variables was performed using inverse probability weights of exposure propensity score (candidemia by C. auris), survival regression models (Weibull distribution), and a counting model (negative binomial distribution). A value of 244 (47.6%) of the 512 patients with candidemia died within the first 30 days. The crude mortality in C. auris was 38.1% vs. 51.1% in Candida non-auris (CNA). In the Weibull model, mortality in the C. auris group was lower (adjusted HR: aHR- 0.69, 95% CI: 0.53\u20130.90). Antifungal treatment also decreased mortality, with an aHR of 0.36 (95% CI 0.27\u20130.47), while the presence of septic shock on patient progression increased it, with an aHR of 1.73 (95% CI 1.41\u20132.13). Among the patients who survived, no differences in the length of hospital stay were observed between the C. auris and the CNA groups, with an incidence rate ratio of 0.92 (95% CI: 0.68\u20131.22). Mortality in patients with C. auris bloodstream infections appears lower when adjusted for numerous confounding variables regarding treatment and the presence of septic shock in patient progression. We identified no significant effect of C. auris on the length of hospital stay in surviving patients.<\/jats:p>","DOI":"10.3390\/jof9070715","type":"journal-article","created":{"date-parts":[[2023,6,30]],"date-time":"2023-06-30T01:14:12Z","timestamp":1688087652000},"page":"715","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Mortality Caused by Candida auris Bloodstream Infections in Comparison with Other Candida Species, a Multicentre Retrospective Cohort"],"prefix":"10.3390","volume":"9","author":[{"given":"Cynthia","family":"Ortiz-Roa","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, Universidad Nacional de Colombia, Bogot\u00e1 111321, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4971-9692","authenticated-orcid":false,"given":"Martha Carolina","family":"Valderrama-Rios","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, Universidad Nacional de Colombia, Bogot\u00e1 111321, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebasti\u00e1n Felipe","family":"Sierra-Uma\u00f1a","sequence":"additional","affiliation":[{"name":"Subred Integrada de Servicios de Salud Sur E.S.E. Hospital Tunal, Bogot\u00e1 110621, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Yesid","family":"Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Integral de Emergencias Laura Daniela, Instituto Cardiovascular del Cesar, Centro de Investigaciones Microbiol\u00f3gicas del Cesar (CIMCE), Valledupar 200001, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerardo Antonio","family":"Mu\u00f1et\u00f3n-L\u00f3pez","sequence":"additional","affiliation":[{"name":"Subred Integrada de Servicios de Salud Suroccidente E.S.E. Hospital Suroccidente Kennedy, Bogot\u00e1 110871, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Augusto","family":"Sol\u00f3rzano-Ramos","sequence":"additional","affiliation":[{"name":"Subred Integrada de Servicios de Salud Suroccidente E.S.E. Hospital Suroccidente Kennedy, Bogot\u00e1 110871, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3029-118X","authenticated-orcid":false,"given":"Patricia","family":"Escand\u00f3n","sequence":"additional","affiliation":[{"name":"Grupo de Microbiolog\u00eda, Instituto Nacional de Salud, Bogot\u00e1 111321, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5419-4494","authenticated-orcid":false,"given":"Carlos Arturo","family":"Alvarez-Moreno","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, Universidad Nacional de Colombia, Bogot\u00e1 111321, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0882-9652","authenticated-orcid":false,"given":"Jorge Alberto","family":"Cort\u00e9s","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, Universidad Nacional de Colombia, Bogot\u00e1 111321, Colombia"},{"name":"Infectious Diseases Unit, Hospital Universitario Nacional, Bgoot\u00e1 111321, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,6,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1080\/23744235.2021.1959052","article-title":"Risk factors of septic shock development and thirty-day mortality with a predictive model in adult candidemia patients in intensive care units","volume":"53","author":"Suh","year":"2021","journal-title":"Infect. 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