{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,21]],"date-time":"2025-12-21T05:19:56Z","timestamp":1766294396131,"version":"3.48.0"},"reference-count":28,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T00:00:00Z","timestamp":1766102400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Southern Illinois University Carbondale"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JoX"],"abstract":"<jats:p>Electronic Nicotine Delivery Systems (ENDSs) expose users to nicotine, volatile organic chemicals, and ultrafine particles that pose emerging toxicological concerns for youth. The prevalence of vaping among college students quadrupled between 2017 and 2019. The Vaping Initiation, Continuation, Termination, or Resumption in Youth (VICTORY) study explored a random sample of 543 undergraduate students at a Midwestern university, using an anonymous online survey, for factors associated with initiation and regular inhalation of vape-derived aerosols. Results showed that 50% of participants had ever used a vape, and 67% had used tobacco, vape, or marijuana. The mean age of first use of tobacco was 15.16 years, significantly younger than the mean ages for vaping (16.33) and marijuana (16.60). There were no significant gender differences in ENDS use, although more males reported tobacco as their first substance (18% difference). Notably, 40% reported non-alcoholic substance or alcohol use in the past 30 days. Decision-tree analysis revealed complex relationships between vaping aerosols, tobacco, alcohol use, marijuana use, and living arrangements. Logistic regression identified key predictors of regular vaping, including higher school year, lower household income, employment status, and younger age at first use. These findings highlight the need for tailored public health interventions and continued monitoring to address the growing trend of youth vaping.<\/jats:p>","DOI":"10.3390\/jox16010003","type":"journal-article","created":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T08:26:36Z","timestamp":1766132796000},"page":"3","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Determinants of Youth Exposure to Nicotine-Containing Aerosols: Findings from a College Survey"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-1813-5856","authenticated-orcid":false,"given":"Chesmi","family":"Kumbalatara","sequence":"first","affiliation":[{"name":"School of Human Sciences, College of Health and Human Sciences, Southern Illinois University, Carbondale, IL 62901, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lindsey","family":"Johnson","sequence":"additional","affiliation":[{"name":"School of Medicine, Southern Illinois University, Springfield, IL 62794, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"MacArthur","sequence":"additional","affiliation":[{"name":"School of Medicine, Southern Illinois University, Springfield, IL 62794, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meungguk","family":"Park","sequence":"additional","affiliation":[{"name":"School of Human Sciences, College of Health and Human Sciences, Southern Illinois University, Carbondale, IL 62901, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8798-0894","authenticated-orcid":false,"given":"Wasantha","family":"Jayawardene","sequence":"additional","affiliation":[{"name":"School of Human Sciences, College of Health and Human Sciences, Southern Illinois University, Carbondale, IL 62901, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,12,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Albadrani, M.S., Tobaiqi, M.A., Muaddi, M.A., Eltahir, H.M., Abdoh, E.S., Aljohani, A.M., Albadawi, E.A., Alzaman, N.S., Abouzied, M.M., and Fadlalmola, H.A. (2024). A global prevalence of electronic nicotine delivery systems (ENDS) use among students: A systematic review and meta-analysis of 4,189,145 subjects. BMC Public Health, 24.","DOI":"10.1186\/s12889-024-20858-2"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Manietta, L., Drake, W., and Jayawardene, W. (2025). Comparative Analysis of Inflammatory and Heavy Metal Biomarkers in Exclusive E-Cigarette Users, Combustible Tobacco Users, and Non-Users Aged 18\u201330: A Cross-Sectional NHANES Analysis. J. Xenobiot., 15.","DOI":"10.3390\/jox15020053"},{"key":"ref_3","unstructured":"Centers for Disease Control and Prevention (2021). Outbreak of Lung Injury Associated with the Use of E-Cigarette, or Vaping, Products, Centers for Disease Control and Prevention (CDC)."},{"key":"ref_4","first-page":"56","article-title":"The Vaping Epidemic in Adolescents","volume":"117","author":"Jones","year":"2020","journal-title":"Mo. Med."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1007\/s11764-019-00753-1","article-title":"Associations between e-cigarette and combustible cigarette use among U.S. cancer survivors: Implications for research and practice","volume":"13","author":"Antwi","year":"2019","journal-title":"J. Cancer Surviv."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1152\/japplphysiol.00717.2019","article-title":"Pod-mod vs. conventional e-cigarettes: Nicotine chemistry, pH, and health effects","volume":"128","author":"Shao","year":"2020","journal-title":"J. Appl. Physiol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.15585\/mmwr.mm7244a1","article-title":"Tobacco Product Use Among U.S. Middle and High School Students\u2014National Youth Tobacco Survey, 2023","volume":"72","author":"Birdsey","year":"2023","journal-title":"MMWR Morb. Mortal. Wkly. Rep."},{"key":"ref_8","unstructured":"Miech, R.A., Johnston, L.D., Patrick, M.E., and O\u2019Malley, P.M. (2025). Monitoring the Future National Survey Results on Drug Use, 1975\u20132024: Overview and Detailed Results for Secondary School Students, Institute for Social Research, University of Michigan."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"e187794","DOI":"10.1001\/jamanetworkopen.2018.7794","article-title":"Association of Electronic Cigarette Use With Subsequent Initiation of Tobacco Cigarettes in US Youths","volume":"2","author":"Berry","year":"2019","journal-title":"JAMA Netw. Open"},{"key":"ref_10","first-page":"95","article-title":"Assessing the Social Influences, Self-Esteem, and Stress of High School Students Who Vape","volume":"94","author":"Jha","year":"2021","journal-title":"Yale J. Biol. Med."},{"key":"ref_11","unstructured":"United States Public Health Service Office of the Surgeon General, National Center for Chronic Disease Prevention, and Health Promotion (US) Office on Smoking and Health (2020). Publications and Reports of the Surgeon General, Smoking Cessation: A Report of the Surgeon General."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Teah, G.E., and Conner, T.S. (2021). Psychological and Demographic Predictors of Vaping and Vaping Susceptibility in Young Adults. Front. Psychol., 12.","DOI":"10.3389\/fpsyg.2021.659206"},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Sapru, S., Vardhan, M., Li, Q., Guo, Y., Li, X., and Saxena, D. (2020). E-cigarettes use in the United States: Reasons for use, perceptions, and effects on health. BMC Public Health, 20.","DOI":"10.1186\/s12889-020-09572-x"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"e33","DOI":"10.1016\/j.amepre.2016.10.036","article-title":"Overview of Electronic Nicotine Delivery Systems: A Systematic Review","volume":"52","author":"Glasser","year":"2017","journal-title":"Am. J. Prev. Med."},{"key":"ref_15","unstructured":"IBM Corp. (IBM SPSS Statistics for Windows, 2022). IBM SPSS Statistics for Windows, version 29.0."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Breiman, L. (2017). Classification and Regression Trees, Routledge.","DOI":"10.1201\/9781315139470"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"558","DOI":"10.4097\/kja.19087","article-title":"Multicollinearity and misleading statistical results","volume":"72","author":"Kim","year":"2019","journal-title":"Korean J. Anesthesiol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.4187\/respcare.10629","article-title":"Vaping Behavior in Young Adults During the COVID-19 Pandemic","volume":"68","author":"Henn","year":"2023","journal-title":"Respir. Care"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1111\/add.12659","article-title":"Electronic cigarettes: Review of use, content, safety, effects on smokers and potential for harm and benefit","volume":"109","author":"Hajek","year":"2014","journal-title":"Addiction"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1111\/add.12150","article-title":"\u2018Vaping\u2019 profiles and preferences: An online survey of electronic cigarette users","volume":"108","author":"Dawkins","year":"2013","journal-title":"Addiction"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1179173X221087524","DOI":"10.1177\/1179173X221087524","article-title":"E-Cigarettes\u2014A review of the evidence\u2014Harm versus harm reduction","volume":"15","author":"Feeney","year":"2022","journal-title":"Tob. Use Insights"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"e20173594","DOI":"10.1542\/peds.2017-3594","article-title":"Electronic Cigarette Use and Progression From Experimentation to Established Smoking","volume":"141","author":"Chaffee","year":"2018","journal-title":"Pediatrics"},{"key":"ref_23","unstructured":"National Institute on Drug Abuse (NIDA) (2025, January 02). Vaping Devices (Electronic Cigarettes) DrugFacts, Available online: https:\/\/nida.nih.gov\/publications\/drugfacts\/vaping-devices-electronic-cigarettes."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1093\/ntr\/ntu156","article-title":"Perception of e-cigarette harm and its correlation with use among U.S. adolescents","volume":"17","author":"Amrock","year":"2015","journal-title":"Nicotine Tob. Res."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1542\/peds.2015-0639","article-title":"Psychosocial Factors Associated With Adolescent Electronic Cigarette and Cigarette Use","volume":"136","author":"Berhane","year":"2015","journal-title":"Pediatrics"},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Kreslake, J.M., O\u2019Connor, K.M., Liu, M., Vallone, D.M., and Hair, E. (2023). A resurgence of e-cigarette use among adolescents and young adults late in the COVID-19 pandemic. PLoS ONE, 18.","DOI":"10.1371\/journal.pone.0282894"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1080\/28367138.2024.2365651","article-title":"Vaping Cessation Attempts and Intentions Among Undergraduate Students: Insights into Interventions","volume":"39","author":"Jayawardene","year":"2025","journal-title":"J. Coll. Stud. Ment. Health"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1089\/chi.2014.0002","article-title":"Discrepant Body Mass Index: Behaviors Associated with Height and Weight Misreporting among US Adolescents from the National Youth Physical Activity and Nutrition Study","volume":"10","author":"Jayawardene","year":"2014","journal-title":"Child. Obes."}],"container-title":["Journal of Xenobiotics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2039-4713\/16\/1\/3\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,21]],"date-time":"2025-12-21T05:15:29Z","timestamp":1766294129000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2039-4713\/16\/1\/3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,19]]},"references-count":28,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,2]]}},"alternative-id":["jox16010003"],"URL":"https:\/\/doi.org\/10.3390\/jox16010003","relation":{},"ISSN":["2039-4713"],"issn-type":[{"type":"electronic","value":"2039-4713"}],"subject":[],"published":{"date-parts":[[2025,12,19]]}}}