{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T05:36:13Z","timestamp":1778304973279,"version":"3.51.4"},"reference-count":33,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2021,10,12]],"date-time":"2021-10-12T00:00:00Z","timestamp":1633996800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>Electroretinography (ERG) is an important and well-established examination for retinal and visual pathway diseases. This study reviewed the medical records of patients who received full-field ERG (ffERG) at a single medical center between 2012 and 2019, which was an 8-year experience in the clinical contribution of ERG. Based on the indication for scheduling ffERG and the final diagnosis, patients could be classified into six groups: \u2018retinal dystrophies\u2019, \u2018other retinal or macular diseases\u2019, \u2018optic neuropathies\u2019, \u2018visual complaints\u2019, \u2018systemic diseases\u2019, and \u2018others\u2019. A total of 1921 full-field electroretinograms (ffERGs) (1655 patients) were included. The average number of ffERGs performed per year was 262 and the number of annual ffERGs was constant. The \u2018retinal dystrophies\u2019 group accounted for 36.5% of the studied population, followed by the \u2018other retinal or macular diseases\u2019 group (20.2%). The most common systemic disease was central nervous system disease. The rates of abnormal ffERGs in the \u2018systemic diseases\u2019, \u2018optic neuropathies\u2019, and \u2018visual complaints\u2019 groups were 27.3%, 22.6%, and 10.1%, respectively (p &lt; 0.001). Higher rates were found in patients &lt;20 years old in the \u2018systemic diseases\u2019 and \u2018optic neuropathies\u2019 groups; epilepsy and optic nerve atrophy were the most common diagnoses, respectively. In brief, by quantifying the functional response in the retina, ffERG is indispensable for diagnosis and prognosis in ophthalmologic and multidisciplinary practice.<\/jats:p>","DOI":"10.3390\/jpm11101022","type":"journal-article","created":{"date-parts":[[2021,10,13]],"date-time":"2021-10-13T06:38:41Z","timestamp":1634107121000},"page":"1022","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The Clinical Contribution of Full-Field Electroretinography and 8-Year Experiences of Application in a Tertiary Medical Center"],"prefix":"10.3390","volume":"11","author":[{"given":"Jung-Je","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Medical Education, National Taiwan University Hospital, Taipei 10002, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chu-Hsuan","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Cathay General Hospital, Taipei 10002, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4328-8716","authenticated-orcid":false,"given":"Chang-Hao","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, National Taiwan University Hospital, Taipei 10002, Taiwan"},{"name":"Department of Ophthalmology, College of Medicine, National Taiwan University, Taipei 10002, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chung-May","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, National Taiwan University Hospital, Taipei 10002, Taiwan"},{"name":"Department of Ophthalmology, College of Medicine, National Taiwan University, Taipei 10002, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5766-3057","authenticated-orcid":false,"given":"Chao-Wen","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, National Taiwan University Hospital, Taipei 10002, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tzyy-Chang","family":"Ho","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, National Taiwan University Hospital, Taipei 10002, Taiwan"},{"name":"Department of Ophthalmology, College of Medicine, National Taiwan University, Taipei 10002, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang-Ping","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, National Taiwan University Hospital, Taipei 10002, Taiwan"},{"name":"Department of Ophthalmology, College of Medicine, National Taiwan University, Taipei 10002, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2258-154X","authenticated-orcid":false,"given":"Yi-Ting","family":"Hsieh","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, National Taiwan University Hospital, Taipei 10002, Taiwan"},{"name":"Department of Ophthalmology, College of Medicine, National Taiwan University, Taipei 10002, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0461-8778","authenticated-orcid":false,"given":"Po-Ting","family":"Yeh","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, National Taiwan University Hospital, Taipei 10002, Taiwan"},{"name":"Department of Ophthalmology, College of Medicine, National Taiwan University, Taipei 10002, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8247-7018","authenticated-orcid":false,"given":"Tso-Ting","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, National Taiwan University Hospital, Taipei 10002, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pei-Lung","family":"Chen","sequence":"additional","affiliation":[{"name":"Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei 10002, Taiwan"},{"name":"Graduate Institute of Medical Genomics and Proteomics, College of Medicine, National Taiwan University, Taipei 10002, Taiwan"},{"name":"Department of Medical Genetics, National Taiwan University Hospital, Taipei 10002, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ta-Ching","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, National Taiwan University Hospital, Taipei 10002, Taiwan"},{"name":"Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei 10002, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,10,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/S1350-9462(03)00049-1","article-title":"The Assessment of L- and M-Cone Specific Electroretinographical Signals in the Normal and Abnormal Human Retina","volume":"22","author":"Kremers","year":"2003","journal-title":"Prog. 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