{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T01:46:15Z","timestamp":1783561575333,"version":"3.55.0"},"reference-count":81,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,1,7]],"date-time":"2022-01-07T00:00:00Z","timestamp":1641513600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>Huntington\u2019s disease (HD) is a rare and complex condition where affected individuals, family members, caregivers, and clinicians face a number of both long-term and fluctuating challenges. The predominant biomedical framework adopted in HD to date has traditionally viewed it as a brain disorder first and foremost. As a consequence, one of the most challenging aspects of the condition\u2014psychological difficulties and their care\u2014is often not given the emphasis it deserves in everyday clinical practice. Here, we propose a manifesto outlining five points to address the quality, effectiveness, availability, and accessibility of psychological care in HD. These include (1) Listening to People with HD, (2) Reformulating Difficulties Psychologically, (3) Exploring New Interventions, (4) Increasing Psychological Provision, and (5) Learning from Other Conditions. As the search for a cure continues, we hope that this manifesto will create a new impetus towards refining the current approach to psychological difficulties in HD and ultimately improve the quality of life of the tens of thousands of families affected by HD worldwide.<\/jats:p>","DOI":"10.3390\/jpm12010064","type":"journal-article","created":{"date-parts":[[2022,1,9]],"date-time":"2022-01-09T20:21:56Z","timestamp":1641759716000},"page":"64","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["More than Just a Brain Disorder: A Five-Point Manifesto for Psychological Care for People with Huntington\u2019s Disease"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8129-6151","authenticated-orcid":false,"given":"Nicol\u00f2","family":"Zarotti","sequence":"first","affiliation":[{"name":"Division of Health Research, Faculty of Health and Medicine, Lancaster University, Lancaster LA1 4YG, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6769-771X","authenticated-orcid":false,"given":"Maria","family":"Dale","sequence":"additional","affiliation":[{"name":"Mill Lodge Huntington\u2019s Disease Inpatient and Community Service, Leicestershire Partnership NHS Trust, Leicester LE19 4SL, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1484-2703","authenticated-orcid":false,"given":"Fiona J. R.","family":"Eccles","sequence":"additional","affiliation":[{"name":"Division of Health Research, Faculty of Health and Medicine, Lancaster University, Lancaster LA1 4YG, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5071-4077","authenticated-orcid":false,"given":"Jane","family":"Simpson","sequence":"additional","affiliation":[{"name":"Division of Health Research, Faculty of Health and Medicine, Lancaster University, Lancaster LA1 4YG, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,1,7]]},"reference":[{"key":"ref_1","first-page":"317","article-title":"On chorea","volume":"26","author":"Huntington","year":"1872","journal-title":"Med. Surg. Rep."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.4088\/JCP.v69n1111","article-title":"Obsessive and Compulsive Symptoms in Prediagnosed Huntington\u2019s Disease","volume":"69","author":"Beglinger","year":"2008","journal-title":"J. Clin. Psychiatry"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1176\/jnp.2007.19.4.441","article-title":"Psychopathology in verified Huntington\u2019s disease gene carriers","volume":"19","author":"Kingma","year":"2007","journal-title":"J. Neuropsychiatry Clin. Neurosci."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/1750-1172-5-40","article-title":"Huntington\u2019s disease: A clinical review","volume":"5","author":"Roos","year":"2010","journal-title":"Orphanet J. Rare Dis."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1055\/s-2007-971176","article-title":"Huntington\u2019s disease","volume":"27","author":"Walker","year":"2007","journal-title":"Semin. Neurol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1136\/jnnp-2013-307343","article-title":"Neuropsychiatric symptoms in a European Huntington\u2019s disease cohort (REGISTRY)","volume":"85","author":"Craufurd","year":"2014","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1176\/appi.neuropsych.14100265","article-title":"Anxiety in Huntington\u2019s disease","volume":"27","author":"Dale","year":"2015","journal-title":"J. Neuropsychiatry Clin. Neurosci."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1093\/arclin\/acy085","article-title":"New perspectives on emotional processing in people with symptomatic Huntington\u2019s disease: Impaired emotion regulation and recognition of emotional body language","volume":"34","author":"Zarotti","year":"2019","journal-title":"Arch. Clin. Neuropsychol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.jad.2011.10.031","article-title":"Suicidality in Huntington\u2019s disease","volume":"136","author":"Hubers","year":"2012","journal-title":"J. Affect. Disord."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"e02151","DOI":"10.1002\/brb3.2151","article-title":"Cognitive and behavioral associated changes in manifest Huntington disease: A retrospective cross-sectional study","volume":"11","author":"Migliore","year":"2021","journal-title":"Brain Behav."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2741\/S355","article-title":"A review of cognition in Huntington\u2019s disease","volume":"5","author":"Dumas","year":"2013","journal-title":"Front. Biosci."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"(1993). Huntington\u2019s Disease Collaborative Research Group A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington\u2019s disease chromosomes. Cell, 72, 971\u2013983.","DOI":"10.1016\/0092-8674(93)90585-E"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1177\/1359105312444646","article-title":"Psychological well-being in persons affected by Huntington\u2019s disease: A comparison of at-risk, prodromal, and symptomatic groups","volume":"18","author":"Chisholm","year":"2013","journal-title":"J. Health Psychol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/s10897-014-9755-y","article-title":"The Psychological Impact of Predictive Genetic Testing for Huntington\u2032s Disease: A Systematic Review of the Literature","volume":"24","author":"Crozier","year":"2014","journal-title":"J. Genet. Couns."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"453","DOI":"10.3389\/fneur.2019.00453","article-title":"Genetic Counseling in Huntington\u2019s Disease: Potential New Challenges on Horizon?","volume":"10","author":"Migliore","year":"2019","journal-title":"Front. Neurol."},{"key":"ref_16","unstructured":"Wieringa, G., Dale, M., and Eccles, F.J.R. (2021). The experience of a sample of individuals in the United Kingdom living in the pre-manifest stage of Huntington\u2019s disease: An interpretative phenomenological analysis. J. Genet. Couns., 1\u201313."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.pec.2006.08.009","article-title":"To know or not to know: A review of behaviour and suicidal ideation in preclinical Huntington\u2019s disease","volume":"65","author":"Wahlin","year":"2007","journal-title":"Patient Educ. Couns."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1007\/s10897-010-9329-6","article-title":"More appreciation of life or regretting the test? Experiences of living as a mutation carrier of Huntington\u2019s disease","volume":"20","author":"Hagberg","year":"2011","journal-title":"J. Genet. Couns."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1212\/WNL.53.4.801","article-title":"DNA analysis of Huntington\u2019s disease: Five years of experience in Germany, Austria, and Switzerland","volume":"53","author":"Laccone","year":"1999","journal-title":"Neurology"},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Harper, P., Lim, C., and Craufurd, D. (2000). Ten years of presymptomatic testing for Huntington\u2019s disease: The experience of the UK Huntington\u2019s Disease Prediction Consortium. J. Med. Genet., 567\u2013571.","DOI":"10.1136\/jmg.37.8.567"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1016\/j.socscimed.2009.02.049","article-title":"How young people find out about their family history of Huntington\u2019s disease","volume":"68","author":"McKee","year":"2009","journal-title":"Soc. Sci. Med."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1177\/1742395317733793","article-title":"\u2018I have a feeling I can\u2019t speak to anybody\u2019: A thematic analysis of communication perspectives in people with Huntington\u2019s disease","volume":"15","author":"Zarotti","year":"2019","journal-title":"Chronic Illn."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s10897-005-0798-x","article-title":"Thursdays with Marion: The therapist\u2019s tale","volume":"14","author":"Sobel","year":"2005","journal-title":"J. Genet. Couns."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1399-0004.2011.01778.x","article-title":"Adverse childhood experiences of persons at risk for Huntington\u2019s disease or BRCA1\/2 hereditary breast\/ovarian cancer","volume":"81","author":"Wolterbeek","year":"2012","journal-title":"Clin. Genet."},{"key":"ref_25","first-page":"608562","article-title":"Reformulating psychological difficulties in people with Parkinson\u2019s disease: The potential of a social relational approach to disablism","volume":"2013","author":"Simpson","year":"2013","journal-title":"Parkinsons Dis."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.cortex.2019.06.012","article-title":"Validity of irritability in Huntington\u2019s disease: A scoping review","volume":"120","author":"Simpson","year":"2019","journal-title":"Cortex"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2217\/nmt.11.85","article-title":"A standard of care for Huntington\u2019s disease: Who, what and why","volume":"2","author":"Simpson","year":"2012","journal-title":"Neurodegener. Dis. Manag."},{"key":"ref_28","first-page":"61","article-title":"Depression in Parkinson\u2019s disease: A psychosocial viewpoint","volume":"65","author":"Brown","year":"1995","journal-title":"Adv. Neurol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1111\/j.2044-8287.2011.02052.x","article-title":"Perceptions of cause and control of impulse control behaviours in people with Parkinson\u2019s disease","volume":"17","author":"Delaney","year":"2012","journal-title":"Br. J. Health Psychol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.3109\/09638280903514705","article-title":"An interpretative phenomenological analysis of delusions in people with Parkinson\u2019s disease","volume":"32","author":"Todd","year":"2010","journal-title":"Disabil. Rehabil."},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Ekkel, M.R., Depla, M.F.I.A., Verschuur, E.M.L., Veenhuizen, R.B., Hertogh, C.M.P.M., and Onwuteaka-Philipsen, B.D. (2021). Gaining insight into the views of outpatients with Huntington\u2019s disease regarding their future and the way they deal with their poor prognosis: A qualitative study. BMC Palliat. Care, 20.","DOI":"10.1186\/s12904-020-00706-x"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s10880-009-9168-5","article-title":"A comparison of mood and quality of life among people with progressive neurological illnesses and their caregivers","volume":"16","author":"McCabe","year":"2009","journal-title":"J. Clin. Psychol. Med. Settings"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1002\/mds.22412","article-title":"Health-related quality of life in Huntington\u2019s disease: Which factors matter most?","volume":"24","author":"Ho","year":"2009","journal-title":"Mov. Disord."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1007\/s00702-012-0787-x","article-title":"Huntington\u2019s disease from the patient, caregiver and physician\u2019s perspectives: Three sides of the same coin?","volume":"119","author":"Banaszkiewicz","year":"2012","journal-title":"J. Neural Transm."},{"key":"ref_35","first-page":"260","article-title":"A Concept Map of What Helps People with HD Live with their Condition","volume":"4","author":"Smith","year":"2015","journal-title":"J. Huntingt. Dis."},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Lowit, A., and van Teijlingen, E.R. (2005). Avoidance as a strategy of (not) coping: Qualitative interviews with carers of Huntington\u2019s Disease patients. BMC Fam. Pract., 6.","DOI":"10.1186\/1471-2296-6-38"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"381","DOI":"10.3109\/13682820903105145","article-title":"Communication and Huntington\u2019s disease: Qualitative interviews and focus groups with persons with Huntington\u2019s disease, family members, and carers","volume":"45","author":"Hartelius","year":"2010","journal-title":"Int. J. Lang. Commun. Disord."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/cge.14024","article-title":"\u201cI have to start learning how to live with becoming sick\u201d: A scoping review of the lived experiences of people with Huntington\u2019s disease","volume":"101","author":"Mahmood","year":"2022","journal-title":"Clin. Genet."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1111\/papt.12157","article-title":"Understandings of psychological difficulties in people with the Huntington\u2019s disease gene and their expectations of psychological therapy","volume":"91","author":"Theed","year":"2018","journal-title":"Psychol. Psychother. Theory Res. Pract."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1002\/mds.25762","article-title":"Executive functions in premanifest Huntington\u2019s disease","volume":"29","author":"You","year":"2014","journal-title":"Mov. Disord."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"97","DOI":"10.3233\/JHD-2012-120010","article-title":"Visual working memory impairment in premanifest gene-carriers and early Huntington\u2019s disease","volume":"1","author":"Dumas","year":"2012","journal-title":"J. Huntingt. Dis."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"846","DOI":"10.3389\/fpsyg.2019.00846","article-title":"Safer attitude to risky decision-making in premanifest Huntington\u2019s disease subjects","volume":"10","author":"Migliore","year":"2019","journal-title":"Front. Psychol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.parkreldis.2018.09.007","article-title":"Task-switching abilities in pre-manifest Huntington\u2019s disease subjects","volume":"60","author":"Migliore","year":"2019","journal-title":"Park. Relat. Disord."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/s00221-020-05957-x","article-title":"Abnormal visual scanning and impaired mental state recognition in pre-manifest Huntington disease","volume":"239","author":"Meloni","year":"2021","journal-title":"Exp. Brain Res."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neuropsychologia.2018.02.030","article-title":"Exploring emotion regulation and emotion recognition in people with presymptomatic Huntington\u2019s disease: The role of emotional awareness","volume":"112","author":"Zarotti","year":"2018","journal-title":"Neuropsychologia"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1002\/mdc3.12808","article-title":"Movement Disorder Society Task Force Viewpoint: Huntington\u2019s Disease Diagnostic Categories","volume":"6","author":"Ross","year":"2019","journal-title":"Mov. Disord. Clin. Pract."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"231","DOI":"10.3233\/JHD-200418","article-title":"Psychological Interventions for People with Huntington\u2019s Disease: A Call to Arms","volume":"9","author":"Zarotti","year":"2020","journal-title":"J. Huntingt. Dis."},{"key":"ref_48","unstructured":"British Psychological Society (2021). Psychological Interventions for People with Huntington\u2019s Disease, Parkinson\u2019s Disease, Motor Neurone Disease, and Multiple Sclerosis: Evidence-Based Guidance, Lancaster University Press."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"277","DOI":"10.3233\/JHD-210471","article-title":"Experiences of Mindfulness-Based Cognitive Therapy for Premanifest Huntington\u2019s Disease","volume":"10","author":"Eccles","year":"2021","journal-title":"J. Huntingt. Dis."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1002\/jgc4.1229","article-title":"Evaluating a genetic counseling narrative group session for people who have tested positive for the huntington\u2019s disease expansion: An interpretative phenomenological analysis","volume":"29","author":"Spiers","year":"2020","journal-title":"J. Genet. Couns."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"355","DOI":"10.3233\/JHD-180293","article-title":"Clinical management of neuropsychiatric symptoms of huntington disease: Expert-based consensus guidelines on agitation, anxiety, apathy, psychosis and sleep disorders","volume":"7","author":"Anderson","year":"2018","journal-title":"J. Huntingt. Dis."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"710","DOI":"10.3389\/fneur.2019.00710","article-title":"International guidelines for the treatment of Huntington\u2019s disease","volume":"10","author":"Ferreira","year":"2019","journal-title":"Front. Neurol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1111\/j.1365-2702.2007.02276.x","article-title":"Exploring supportive care for individuals affected by Huntington disease and their family caregivers in a community setting","volume":"17","author":"Soltysiak","year":"2008","journal-title":"J. Clin. Nurs."},{"key":"ref_54","unstructured":"Huntington\u2019s Disease Association (2021, November 25). Working with Patients and Families. Available online: https:\/\/www.hda.org.uk\/professionals\/working-with-patients-and-families."},{"key":"ref_55","unstructured":"SHA National Care (2021, November 25). Framework for Huntington\u2019s Disease. Available online: http:\/\/care.hdscotland.org\/."},{"key":"ref_56","unstructured":"The Neurological Alliance (2021, November 25). Parity of Esteem for People Affected by Neurological Conditions, Available online: https:\/\/www.neural.org.uk\/assets\/pdfs\/2017-07-parity-of-esteem.pdf."},{"key":"ref_57","unstructured":"National Institute for Health and Care Excellence (2021, November 25). Depression in Adults with a Chronic Physical Health Problem: Recognition and Management (CG91), Available online: https:\/\/www.nice.org.uk\/guidance\/cg91."},{"key":"ref_58","unstructured":"Scottish Huntington\u2019s Association (2021, November 25). Guiding Principles of the National Care Framework, Available online: http:\/\/care.hdscotland.org\/guiding-principles."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/bjhp.12122","article-title":"Using mixed methods research designs in health psychology: An illustrated discussion from a pragmatist perspective","volume":"20","author":"Bishop","year":"2015","journal-title":"Br. J. Health Psychol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1177\/1359105310377537","article-title":"Mixed Methods in Health Psychology: Theoretical and Practical Considerations of the Third Paradigm","volume":"16","author":"Dures","year":"2010","journal-title":"J. Health Psychol."},{"key":"ref_61","unstructured":"Crossley, M.L. (2000). Rethinking Health Psychology, Open University Press."},{"key":"ref_62","unstructured":"Morse, J.M., and Johnson, J.L. (1991). The Illness Experience: Dimensions of Suffering, Sage Publications Inc."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/BF01173486","article-title":"Illness cognition: Using common sense to understand treatment adherence and affect cognition interactions","volume":"16","author":"Leventhal","year":"1992","journal-title":"Cognit. Ther. Res."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/s40814-020-00631-z","article-title":"A feasibility investigation of mindfulness-based cognitive therapy for people with Huntington\u2019s disease","volume":"6","author":"Eccles","year":"2020","journal-title":"Pilot Feasibility Stud."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1097\/01376517-200106000-00005","article-title":"Remotivation therapy and Huntington\u2019s disease","volume":"33","author":"Sullivan","year":"2001","journal-title":"J. Neurosci. Nurs."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/21678421.2020.1788094","article-title":"Psychological interventions for people with motor neuron disease: A scoping review","volume":"22","author":"Zarotti","year":"2021","journal-title":"Amyotroph. Lateral Scler. Front. Degener."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1111\/papt.12321","article-title":"Psychological interventions for people with Parkinson\u2019s disease in the early 2020s: Where do we stand?","volume":"94","author":"Zarotti","year":"2021","journal-title":"Psychol. Psychother. Theory Res. Pract."},{"key":"ref_68","unstructured":"Simpson, J., Eccles, F.J.R., and Zarotti, N. (2021). Extended Evidence-Based Guidance on Psychological Interventions for Psychological Difficulties in Individuals with Huntington\u2019s Disease, Parkinson\u2019s Disease, Motor Neurone Disease, and Multiple Sclerosis, Lancaster University."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1007\/s10897-013-9666-3","article-title":"An exploration of the experience of Huntington\u2019s disease in family dyads: An interpretative phenomenological analysis","volume":"23","author":"Maxted","year":"2014","journal-title":"J. Genet. Couns."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1136\/jnnp-2012-304636","article-title":"Prevalence of adult Huntington\u2019s disease in the UK based on diagnoses recorded in general practice records","volume":"84","author":"Evans","year":"2013","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1002\/mds.25075","article-title":"The incidence and prevalence of Huntington\u2019s disease: A systematic review and meta-analysis","volume":"27","author":"Pringsheim","year":"2012","journal-title":"Mov. Disord."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/j.1442-2018.2004.00183.x","article-title":"Living with Huntington\u2019s disease: Need for supportive care","volume":"6","author":"Dwason","year":"2004","journal-title":"Nurs. Health Sci."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s11940-012-0166-9","article-title":"Treatment of behavioral and psychological symptoms of Alzheimer\u2019s disease","volume":"14","author":"Corbett","year":"2012","journal-title":"Curr. Treat. Options Neurol."},{"key":"ref_74","doi-asserted-by":"crossref","unstructured":"Pagnini, F., Bosma, C.M., Phillips, D., and Langer, E. (2014). Symptom changes in multiple sclerosis following psychological interventions: A systematic review. BMC Neurol., 14.","DOI":"10.1186\/s12883-014-0222-z"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.3109\/09638288.2010.525287","article-title":"A review of the demographic, clinical and psychosocial correlates of perceived control in three chronic motor illnesses","volume":"33","author":"Eccles","year":"2011","journal-title":"Disabil. Rehabil."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1176\/appi.ajp.2011.10111669","article-title":"Cognitive Behavior Therapy for Depression in Parkinson\u2019s Disease: A Randomized Controlled Trial","volume":"168","author":"Dobkin","year":"2011","journal-title":"Am. J. Psychiatry"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1080\/07317115.2019.1580811","article-title":"Telephone-Delivered Cognitive Behavioural Therapy for Treating Symptoms of Anxiety and Depression in Parkinson\u2019s Disease: A Pilot Trial","volume":"42","author":"Wuthrich","year":"2019","journal-title":"Clin. Gerontol."},{"key":"ref_78","doi-asserted-by":"crossref","unstructured":"Troeung, L., Egan, S.J., and Gasson, N. (2014). A waitlist-controlled trial of group cognitive behavioural therapy for depression and anxiety in Parkinson\u2019s disease. BMC Psychiatry, 14.","DOI":"10.1186\/1471-244X-14-19"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1177\/1352458515576261","article-title":"Distress improves after mindfulness training for progressive MS: A pilot randomised trial","volume":"21","author":"Bogosian","year":"2015","journal-title":"Mult. Scler. J."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1177\/1352458518761187","article-title":"Online meditation training for people with multiple sclerosis: A randomized controlled trial","volume":"25","author":"Cavalera","year":"2019","journal-title":"Mult. Scler. J."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1007\/s00415-019-09329-6","article-title":"Parkinson\u2019s-adapted cognitive stimulation therapy: Feasibility and acceptability in Lewy body spectrum disorders","volume":"266","author":"McCormick","year":"2019","journal-title":"J. Neurol."}],"container-title":["Journal of Personalized Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4426\/12\/1\/64\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T14:13:02Z","timestamp":1760364782000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4426\/12\/1\/64"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,7]]},"references-count":81,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,1]]}},"alternative-id":["jpm12010064"],"URL":"https:\/\/doi.org\/10.3390\/jpm12010064","relation":{},"ISSN":["2075-4426"],"issn-type":[{"value":"2075-4426","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,7]]}}}