{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:52:15Z","timestamp":1787028735113,"version":"build-2736575974"},"reference-count":20,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T00:00:00Z","timestamp":1647820800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Else-Kr\u00f6ner-Fresenius-Center for Digital Health of the TU Dresden and the APC was funded by Fraunhofer.","award":["IIP TransplaBit"],"award-info":[{"award-number":["IIP TransplaBit"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>Cleft lip and palate belong to the most frequent craniofacial anomalies. Secondary osteoplasty is usually performed between 7 and 11 years with the closure of the osseus defect by autologous bone. Due to widespread occurrence of the defect in conjunction with its social significance due to possible esthetic impairments, the outcome of treatment is of substantial interest. The success of the treatment is determined by the precise rebuilding of the dental arch using autologous bone from the iliac crest. A detailed analysis of retrospective data disclosed a lack of essential and structured information to identify success factors for fast regeneration and specify the treatment. Moreover, according to the current status, no comparable process monitoring is possible during osteoplasty due to the lack of sensory systems. Therefore, a holistic approach was developed to determine the parameters for a successful treatment via the incorporation of patient data, the treatment sequences and sensor data gained by an attachable sensor module into a developed Dental Tech Space (DTS). This approach enables heterogeneous data sets to be linked inside of DTS, archiving and analysis, and is also for future considerations of respective patient-specific treatment plans.<\/jats:p>","DOI":"10.3390\/jpm12030506","type":"journal-article","created":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T21:48:42Z","timestamp":1647899322000},"page":"506","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["A Holistic Approach for the Identification of Success Factors in Secondary Cleft Osteoplasty"],"prefix":"10.3390","volume":"12","author":[{"given":"Tom A.","family":"Schr\u00f6der","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, University Hospital Carl Gustav Carus Dresden, Technische Universit\u00e4t Dresden, Fetscherstra\u00dfe 74, 01307 Dresden, Germany"},{"name":"Else Kr\u00f6ner Fresenius Center for Digital Health, Technische Universit\u00e4t Dresden, Fetscherstra\u00dfe 74, 01307 Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Maiwald","sequence":"additional","affiliation":[{"name":"Chair of Material Handling, Technische Universit\u00e4t Dresden, M\u00fcnchner Platz 3, 01187 Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel","family":"Reinicke","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Angewandte Informatik e.V., Schnorrstra\u00dfe 70, 01069 Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7061-4687","authenticated-orcid":false,"given":"Uwe","family":"Teicher","sequence":"additional","affiliation":[{"name":"Fraunhofer Institute for Machine Tools and Forming Technology IWU, N\u00f6thnitzer Stra\u00dfe 44, 01187 Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9170-4833","authenticated-orcid":false,"given":"Andr\u00e9","family":"Seidel","sequence":"additional","affiliation":[{"name":"Fraunhofer Institute for Machine Tools and Forming Technology IWU, N\u00f6thnitzer Stra\u00dfe 44, 01187 Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thorsten","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Chair of Material Handling, Technische Universit\u00e4t Dresden, M\u00fcnchner Platz 3, 01187 Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steffen","family":"Ihlenfeldt","sequence":"additional","affiliation":[{"name":"Fraunhofer Institute for Machine Tools and Forming Technology IWU, N\u00f6thnitzer Stra\u00dfe 44, 01187 Dresden, Germany"},{"name":"Chair of Machine Tools Development and Adaptive Controls, Technische Universit\u00e4t Dresden, Helmholtzstra\u00dfe 7a, 01069 Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karol","family":"Kozak","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Angewandte Informatik e.V., Schnorrstra\u00dfe 70, 01069 Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Winnie","family":"Pradel","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, University Hospital Carl Gustav Carus Dresden, Technische Universit\u00e4t Dresden, Fetscherstra\u00dfe 74, 01307 Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00fcnter","family":"Lauer","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, University Hospital Carl Gustav Carus Dresden, Technische Universit\u00e4t Dresden, Fetscherstra\u00dfe 74, 01307 Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anas","family":"Ben Achour","sequence":"additional","affiliation":[{"name":"Else Kr\u00f6ner Fresenius Center for Digital Health, Technische Universit\u00e4t Dresden, Fetscherstra\u00dfe 74, 01307 Dresden, Germany"},{"name":"Fraunhofer Institute for Machine Tools and Forming Technology IWU, N\u00f6thnitzer Stra\u00dfe 44, 01187 Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/nrg2933","article-title":"Cleft lip and palate: Understanding genetic and environmental influences","volume":"12","author":"Dixon","year":"2011","journal-title":"Nat. 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