{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T03:31:01Z","timestamp":1781753461909,"version":"3.54.5"},"reference-count":16,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T00:00:00Z","timestamp":1650585600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Taiwan Ministry of Science and Technology","award":["MOST 110-2314-B-016-051"],"award-info":[{"award-number":["MOST 110-2314-B-016-051"]}]},{"name":"Ministry of National Defense Medical Affairs Bureau","award":["MND-MAB-C05-111019"],"award-info":[{"award-number":["MND-MAB-C05-111019"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>Purpose: Orbital floor fractures commonly occur during orbital trauma. Currently, the indications for orbital fracture repair and the appropriate duration between trauma and surgical intervention remain controversial. Methods: Eyes diagnosed with orbital floor fractures that underwent reconstruction surgery were retrospectively reviewed. Demographic data were analyzed. Patients were classified based on the timing of the surgical intervention after injury. Ocular limitation and diplopia were evaluated preoperatively and postoperatively at one week, one month, and three months. Results: Two hundred seventy eyes of 270 patients (174 males and 96 females, mean age: 40.9 \u00b1 16.3 years) were identified. The mean duration from injury to surgical intervention was 18.0 \u00b1 21.2 days (range: 0\u2013117 days). In the subgroup analysis, compared to delayed treatment, the early repair of floor fractures, i.e., within 7 days, was associated with significant motility and diplopia resolution at one week (p = 0.001, p &lt; 0.001), one month (p &lt; 0.001, p &lt; 0.001), and three months (p &lt; 0.001, p &lt; 0.001). Sex and the duration from injury to repair were significantly associated with postoperative ocular motility (p = 0.001; p = 0.024) and diplopia (p &lt; 0.001; p = 0.008) at three months. Multivariate analysis revealed that preoperative limitation and diplopia were correlated with postoperative limitation (p = 0.007) and diplopia (p = 0.001), respectively. Conclusions: The duration between orbital floor fracture and surgical treatment was associated with postoperative limitation and diplopia. Our results suggest that earlier intervention in symptomatic patients with orbital trauma may improve postoperative visual function.<\/jats:p>","DOI":"10.3390\/jpm12050671","type":"journal-article","created":{"date-parts":[[2022,4,23]],"date-time":"2022-04-23T21:39:45Z","timestamp":1650749985000},"page":"671","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Early Intervention in Orbital Floor Fractures: Postoperative Ocular Motility and Diplopia Outcomes"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4390-0389","authenticated-orcid":false,"given":"Cherng-Ru","family":"Hsu","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan"},{"name":"Department of Medical Science, Graduate School, National Defense Medical Center, Taipei 11490, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4745-4088","authenticated-orcid":false,"given":"Lung-Chi","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Hao","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan"},{"name":"Department of Medical Science, Graduate School, National Defense Medical Center, Taipei 11490, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke-Hung","family":"Chien","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,4,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1055\/s-0037-1607447","article-title":"Complications of Midface Fractures","volume":"33","author":"Lozada","year":"2017","journal-title":"Facial Plast. Surg."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s00417-021-05327-5","article-title":"Correlation between surgical timing and postoperative ocular motility in orbital blowout fractures","volume":"260","author":"Yamanaka","year":"2021","journal-title":"Graefe\u2019s Arch. Clin. Exp. Ophthalmol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"169e","DOI":"10.1097\/PRS.0000000000004600","article-title":"Functional Outcomes of Late Posttraumatic Enophthalmos Correction","volume":"142","author":"McRae","year":"2018","journal-title":"Plast. Reconstr. Surg."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1016\/j.ophtha.2017.12.015","article-title":"Conservatively treated orbital blowout fractures: Spontaneous radiologic improvement","volume":"125","author":"Young","year":"2018","journal-title":"Ophthalmology"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1016\/S0161-6420(00)00334-1","article-title":"Pediatric orbital floor fracture: Direct extraocular muscle involvement","volume":"107","author":"Egbert","year":"2000","journal-title":"Ophthalmology"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1097\/IOP.0000000000000993","article-title":"Effect of Time to Operative Intervention on Motility Outcomes Following Orbital Floor Fracture Repair in Children","volume":"34","author":"Mehta","year":"2018","journal-title":"Ophthalmic Plast. Reconstr. Surg."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.2147\/OPTH.S80463","article-title":"Management of orbital fractures: Challenges and solutions","volume":"9","author":"Boyette","year":"2015","journal-title":"Clin. Ophthalmol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1016\/S0161-6420(02)01057-6","article-title":"Clinical recommendations for repair of isolated orbital floor fractures: An evidence-based analysis","volume":"109","author":"Burnstine","year":"2002","journal-title":"Ophthalmology"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.joms.2019.09.025","article-title":"Does Early Repair of Orbital Fractures Result in Superior Patient Outcomes? A Systematic Review and Meta-Analysis","volume":"78","author":"Jazayeri","year":"2020","journal-title":"J. Oral Maxillofac. Surg."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"S91","DOI":"10.1097\/SAP.0000000000000726","article-title":"Surgical Timing and Fracture Type on the Outcome of Diplopia After Orbital Fracture Repair","volume":"76","author":"Yu","year":"2016","journal-title":"Ann. Plast. Surg."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1136\/bjophthalmol-2017-310312","article-title":"Impact of surgical timing of postoperative ocular motility in orbital blowout fractures","volume":"102","author":"Yamanaka","year":"2017","journal-title":"Br. J. Ophthalmol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.joco.2016.09.001","article-title":"The predictive factors of diplopia and extraocular movement limitations in isolated pure blow-out fracture","volume":"29","author":"Kasaee","year":"2016","journal-title":"J. Curr. Ophthalmol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1097\/00001665-200401000-00035","article-title":"Surgical Timing in Orbital Fracture Treatment: Experience with 108 Consecutive Cases","volume":"15","author":"Matteini","year":"2004","journal-title":"J. Craniofacial Surg."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.joms.2016.10.036","article-title":"Does Preoperative Diplopia Determine the Incidence of Postoperative Diplopia After Repair of Orbital Floor Fracture? An Institutional Review","volume":"75","author":"Ramphul","year":"2017","journal-title":"J. Oral Maxillofac. Surg."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1097\/IOP.0000000000000511","article-title":"Outcomes of Orbital Blow-Out Fracture Repair Performed Beyond 6 Weeks After Injury","volume":"32","author":"Scawn","year":"2016","journal-title":"Ophthalmic Plast. Reconstr. Surg."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1097\/SCS.0b013e3181e47c45","article-title":"Preoperative diplopia: The most important prognostic factor for diplopia after surgical repair of pure orbital blowout fracture","volume":"21","author":"Tahiri","year":"2010","journal-title":"J. Craniofacial Surg."}],"container-title":["Journal of Personalized Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4426\/12\/5\/671\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T22:58:40Z","timestamp":1760137120000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4426\/12\/5\/671"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,22]]},"references-count":16,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2022,5]]}},"alternative-id":["jpm12050671"],"URL":"https:\/\/doi.org\/10.3390\/jpm12050671","relation":{},"ISSN":["2075-4426"],"issn-type":[{"value":"2075-4426","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,22]]}}}