{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T22:09:54Z","timestamp":1771970994683,"version":"3.50.1"},"reference-count":129,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,7,10]],"date-time":"2022-07-10T00:00:00Z","timestamp":1657411200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>COVID-19 has been responsible for widespread morbidity and mortality worldwide. Invasive mucormycosis has death rates scaling 80%. India, one of the countries hit worst by the pandemic, is also a hotbed with the highest death rates for mucormycosis. Cancer, a ubiquitously present menace, also contributes to higher case fatality rates. All three entities studied here are individual, massive healthcare threats. The danger of one disease predisposing to the other, the poor performance status of patients with all three diseases, the impact of therapeutics for one disease on the pathology and therapy of the others all warrant physicians having a better understanding of the interplay. This is imperative so as to effectively establish control over the individual patient and population health. It is important to understand the interactions to effectively manage all three entities together to reduce overall morbidity. In this review article, we search for an inter-relationship between the COVID-19 pandemic, emerging mucormycosis, and the global giant, cancer.<\/jats:p>","DOI":"10.3390\/jpm12071119","type":"journal-article","created":{"date-parts":[[2022,7,10]],"date-time":"2022-07-10T22:48:00Z","timestamp":1657493280000},"page":"1119","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["COVID-19, Mucormycosis and Cancer: The Triple Threat\u2014Hypothesis or Reality?"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1640-7342","authenticated-orcid":false,"given":"Ishika","family":"Mahajan","sequence":"first","affiliation":[{"name":"Department of Medical Oncology, Apollo Cancer Centre, Chennai 600001, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8332-8033","authenticated-orcid":false,"given":"Aruni","family":"Ghose","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Barts Cancer Centre, St. Bartholomew\u2019s Hospital, Barts Health NHS Trust, London KT1 2EE, UK"},{"name":"Department of Medical Oncology, Mount Vernon Cancer Centre, East and North Hertfordshire NHS Trust, London KT1 2EE, UK"},{"name":"Department of Medical Oncology, Medway NHS Foundation Trust, Windmill Road, Gillingham ME7 5NY, UK"},{"name":"Division of Research, Academics and Cancer Control, Saroj Gupta Cancer Centre and Research Institute, Kolkata 700001, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepika","family":"Gupta","sequence":"additional","affiliation":[{"name":"Microbiology, College of Medicine and Sagore Dutta Hospital, Kolkata 700001, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7170-4476","authenticated-orcid":false,"given":"Manasi","family":"Manasvi","sequence":"additional","affiliation":[{"name":"Internal Medicine, Kasturba Medical College, Mangalore 574142, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saisha","family":"Bhandari","sequence":"additional","affiliation":[{"name":"Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh 133301, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aparimita","family":"Das","sequence":"additional","affiliation":[{"name":"Faculty of Allied Health Sciences, Chettinad Academy of Research and Education, Chennai 600001, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabet","family":"Sanchez","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Medway NHS Foundation Trust, Windmill Road, Gillingham ME7 5NY, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2512-6131","authenticated-orcid":false,"given":"Stergios","family":"Boussios","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Medway NHS Foundation Trust, Windmill Road, Gillingham ME7 5NY, UK"},{"name":"Faculty of Life Sciences & Medicine, School of Cancer & Pharmaceutical Sciences, King\u2019s College London, London SE1 9RT, UK"},{"name":"AELIA Organization, 9th Km Thessaloniki-Thermi, 57001 Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Revythis, A., Shah, S., Enyioma, S., Ghose, A., Patel, M., Karathanasi, A., Sanchez, E., and Boussios, S. 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