{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T17:05:06Z","timestamp":1775581506715,"version":"3.50.1"},"reference-count":45,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2022,7,28]],"date-time":"2022-07-28T00:00:00Z","timestamp":1658966400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Research Foundation of Korea (NRF)","award":["NRF-2020R1I1A1A01063604"],"award-info":[{"award-number":["NRF-2020R1I1A1A01063604"]}]},{"name":"National Research Foundation of Korea (NRF)","award":["K2212061"],"award-info":[{"award-number":["K2212061"]}]},{"DOI":"10.13039\/501100003725","name":"Korean government (Ministry of Education)","doi-asserted-by":"publisher","award":["NRF-2020R1I1A1A01063604"],"award-info":[{"award-number":["NRF-2020R1I1A1A01063604"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"Korean government (Ministry of Education)","doi-asserted-by":"publisher","award":["K2212061"],"award-info":[{"award-number":["K2212061"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002642","name":"Korea University","doi-asserted-by":"publisher","award":["NRF-2020R1I1A1A01063604"],"award-info":[{"award-number":["NRF-2020R1I1A1A01063604"]}],"id":[{"id":"10.13039\/501100002642","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002642","name":"Korea University","doi-asserted-by":"publisher","award":["K2212061"],"award-info":[{"award-number":["K2212061"]}],"id":[{"id":"10.13039\/501100002642","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>Patients with severe pneumonia of unknown etiology presented in December 2019 in Wuhan, China. A novel coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), was isolated from the respiratory tracts of these patients. The World Health Organization (WHO) defined respiratory diseases due to SARS-CoV-2 infection as coronavirus disease 2019 (COVID-19). Many researchers have reported that the nasal cavity is an important initial route for SARS-CoV-2 infection and that the spike protein of this virus binds to angiotensin-converting enzyme 2 (ACE2) on epithelial cell surfaces. Therefore, COVID-19 is thought to significantly affect nasal symptoms and various rhinological diseases. In this review, we summarize the association between COVID-19 and various rhinological diseases, such as olfactory dysfunction, rhinosinusitis, and allergic rhinitis.<\/jats:p>","DOI":"10.3390\/jpm12081234","type":"journal-article","created":{"date-parts":[[2022,7,28]],"date-time":"2022-07-28T22:43:26Z","timestamp":1659048206000},"page":"1234","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["SARS-CoV-2 Infection (COVID-19) and Rhinologic Manifestation: Narrative Review"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7811-2692","authenticated-orcid":false,"given":"Seung Hoon","family":"Lee","sequence":"first","affiliation":[{"name":"Division of Rhinology, Department of Otorhinolaryngology-Head and Neck Surgery, Korea University Ansan Hospital, Ansan 15355, Korea"},{"name":"Division of Rhinology, Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul 02841, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1287-6961","authenticated-orcid":false,"given":"Min Young","family":"Seo","sequence":"additional","affiliation":[{"name":"Division of Rhinology, Department of Otorhinolaryngology-Head and Neck Surgery, Korea University Ansan Hospital, Ansan 15355, Korea"},{"name":"Division of Rhinology, Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul 02841, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S0140-6736(20)30211-7","article-title":"Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study","volume":"395","author":"Chen","year":"2020","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1056\/NEJMoa2002032","article-title":"Clinical Characteristics of Coronavirus Disease 2019 in China","volume":"382","author":"Guan","year":"2020","journal-title":"N. 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