{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T04:45:14Z","timestamp":1785386714575,"version":"3.55.0"},"reference-count":105,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2022,8,22]],"date-time":"2022-08-22T00:00:00Z","timestamp":1661126400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>Vascular surgery patients have multiple comorbidities and are at high risk for perioperative complications. Aortic repair surgery has greatly evolved in recent years, with an increasing predominance of endovascular techniques (EVAR). The incidence of cardiac complications is significantly reduced with endovascular repair, but high-risk patients require postoperative ST-segment monitoring. Open aortic repair may portend a prohibitive risk of respiratory complications that could be a contraindication for surgery. This risk is greatly reduced in the case of an endovascular approach, and general anesthesia should be avoided whenever possible in the case of endovascular repair. Preoperative renal function and postoperative kidney injury are powerful determinants of short- and long-term outcome, so that preoperative risk stratification and secondary prevention are critical tasks. Intraoperative renal protection with selective renal and distal aortic perfusion is essential during open repair. EVAR has lower rates of postoperative renal failure compared to open repair, with approximately half the risk for acute kidney injury (AKI) and one-third of the risk of hemodialysis requirement. Spinal cord ischemia used to be the most distinctive and feared complication of aortic repair. The risk has significantly decreased since the beginning of aortic surgery, with advances in surgical technique and spinal protection protocols, and is lower with endovascular repair. Endovascular repair avoids extensive aortic dissection and aortic cross-clamping and is generally associated with reduced blood loss and less coagulopathy. The intensive care physician must be aware that aortic repair surgery has an impact on every organ system, and the importance of early recognition of organ failure cannot be overemphasized.<\/jats:p>","DOI":"10.3390\/jpm12081351","type":"journal-article","created":{"date-parts":[[2022,8,22]],"date-time":"2022-08-22T21:30:34Z","timestamp":1661203834000},"page":"1351","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Postoperative Intensive Care Management of Aortic Repair"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6239-0804","authenticated-orcid":false,"given":"Stefano","family":"De Paulis","sequence":"first","affiliation":[{"name":"Fondazione Policlinico Gemelli IRCCS, 00168 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriella","family":"Arlotta","sequence":"additional","affiliation":[{"name":"Fondazione Policlinico Gemelli IRCCS, 00168 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Calabrese","sequence":"additional","affiliation":[{"name":"Fondazione Policlinico Gemelli IRCCS, 00168 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8999-0343","authenticated-orcid":false,"given":"Filippo","family":"Corsi","sequence":"additional","affiliation":[{"name":"Fondazione Policlinico Gemelli IRCCS, 00168 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Temistocle","family":"Taccheri","sequence":"additional","affiliation":[{"name":"Fondazione Policlinico Gemelli IRCCS, 00168 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9640-922X","authenticated-orcid":false,"given":"Maria","family":"Antoniucci","sequence":"additional","affiliation":[{"name":"Fondazione Policlinico Gemelli IRCCS, 00168 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Martinelli","sequence":"additional","affiliation":[{"name":"Fondazione Policlinico Gemelli IRCCS, 00168 Rome, Italy"},{"name":"Department of Cardiovascular Sciences, Universit\u00e0 Cattolica del Sacro Cuore, 00168 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Bevilacqua","sequence":"additional","affiliation":[{"name":"Fondazione Policlinico Gemelli IRCCS, 00168 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2212-3226","authenticated-orcid":false,"given":"Giovanni","family":"Tinelli","sequence":"additional","affiliation":[{"name":"Fondazione Policlinico Gemelli IRCCS, 00168 Rome, Italy"},{"name":"Department of Cardiovascular Sciences, Universit\u00e0 Cattolica del Sacro Cuore, 00168 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franco","family":"Cavaliere","sequence":"additional","affiliation":[{"name":"Fondazione Policlinico Gemelli IRCCS, 00168 Rome, Italy"},{"name":"Department of Cardiovascular Sciences, Universit\u00e0 Cattolica del Sacro Cuore, 00168 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,8,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1097\/00000658-200210000-00010","article-title":"Thoracoabdominal aneurysm repair: Results with 337 operations per-formed over 15-year interval","volume":"236","author":"Cambria","year":"2002","journal-title":"Ann. Surg."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/0741-5214(93)90421-H","article-title":"Experience with 1509 patients undergoing thoracoabdominal aneurysm op-erations","volume":"17","author":"Svensson","year":"1993","journal-title":"J. Vasc. Surg."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1093\/eurheartj\/ehy462","article-title":"ESC Scientific Document Group. Fourth universal definition of myocardial infarc-tion (2018)","volume":"40","author":"Thygesen","year":"2019","journal-title":"Eur. Heart J."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1016\/j.jacc.2003.05.001","article-title":"Association of cardiac troponin, CKMB, and postoperative myocardial ischemia with long-term survival after major vascular surgery","volume":"42","author":"Landesberg","year":"2003","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1097\/00000542-200505000-00004","article-title":"Early and delayed myocardial infarction after abdominal aortic surgery","volume":"102","author":"Perel","year":"2005","journal-title":"Anesthesiology"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1111\/j.1365-2044.2011.06763.x","article-title":"Outcomes in vascular surgical patients with isolated postoperative troponin leak: A meta-analysis","volume":"66","author":"Redfern","year":"2011","journal-title":"Anaesthesia"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/S0741-5214(95)70281-4","article-title":"Hypotermia during elective abdomial aortic aneurysm repair: The high price of avoid-able morbidity","volume":"21","author":"Bush","year":"1995","journal-title":"J. Vasc. Surg."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1308\/003588407X168253","article-title":"Postoperative arrhythmias in general surgical patients","volume":"89","author":"Walsh","year":"2007","journal-title":"Ann. R. Coll. Surg. Engl."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1016\/j.ahj.2010.03.035","article-title":"Risk factors and outcome of new-onset cardiac arrhythmias in vascular surgery patients","volume":"159","author":"Winkel","year":"2010","journal-title":"Am. Heart J."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"2886","DOI":"10.1161\/hc4901.101760","article-title":"C-reactive protein elevation in patients with atrial arrhythmias: Inflammatory mechanisms and persistence of atrial fibrillation","volume":"104","author":"Chung","year":"2001","journal-title":"Circulation"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1007\/BF03009513","article-title":"Stress hormone responses to major intra-abdominal surgery during and im-mediately after sevoflurane-nitrous oxide anaesthesia in elderly patients","volume":"40","author":"Furuya","year":"1993","journal-title":"Can. J. Anaesth."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/0022-4804(87)90128-4","article-title":"Catecholamine-glucocorticoid interactions during surgical stress","volume":"43","author":"Udelsman","year":"1987","journal-title":"J. Surg. Res."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1016\/S0022-5223(19)41183-5","article-title":"Systemic hyper- tension associated with coronary artery bypass sur-gery. Predisposing factors, hemodynamic characteristics, humoral profile, and treatment","volume":"74","author":"Roberts","year":"1977","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1002\/j.1875-9114.1998.tb03924.x","article-title":"Perioperative hypertension","volume":"18","author":"Goldberg","year":"1998","journal-title":"Pharmacotherapy"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/j.anclin.2014.05.001","article-title":"Postoperative ICU Management of vascular surgery patients","volume":"32","author":"Crimi","year":"2014","journal-title":"Anesthesiol. Clinic."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1016\/j.jacc.2009.11.047","article-title":"Endovascular aortic repair versus open surgical repair for descending thoracic aortic disease a systematic review and meta-analysis of comparative studies","volume":"55","author":"Cheng","year":"2010","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1055\/s-0040-1714089","article-title":"Complications and management of the endovascular aortic repair","volume":"8","author":"Chen","year":"2020","journal-title":"Aorta"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.jvs.2017.10.044","article-title":"The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm","volume":"67","author":"Chaikof","year":"2018","journal-title":"J. Vasc. Surg."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1213\/01.ane.0000247805.00342.21","article-title":"Perioperative beta-blockers for preventing surgery-related mortality and morbidity: A systematic review and meta-analysis","volume":"104","author":"Wiesbauer","year":"2007","journal-title":"Anesth. Analg."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1016\/j.jvs.2009.07.002","article-title":"The care of patients with an abdominal aortic aneurysm: The Society for Vascular Surgery practice guidelines","volume":"50","author":"Chaikof","year":"2009","journal-title":"J. Vasc. Surg."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1093\/eurheartj\/ehz467","article-title":"2019 ESC Guidelines for the management of patients with supraventricular tachycardia. The Task Force for the management of patients with supraventricular tachycardia of the European Society of Cardiology (ESC)","volume":"41","author":"Brugada","year":"2020","journal-title":"Eur. Heart J."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.resuscitation.2021.02.010","article-title":"European Resuscitation Council Guidelines 2021: Adult advanced life support","volume":"161","author":"Soar","year":"2021","journal-title":"Resuscitation"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.jvs.2003.10.018","article-title":"Perioperative complications and early outcome after endovascular and open surgical repair of abdominal aortic aneurysms","volume":"39","author":"Elkouri","year":"2004","journal-title":"J. Vasc. Surg."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"581","DOI":"10.7326\/0003-4819-144-8-200604180-00009","article-title":"American College of Physicians. Preoperative pulmonary risk stratification for noncardiothoracic surgery: Systematic re-view for the American College of Physicians","volume":"144","author":"Smetana","year":"2006","journal-title":"Ann. Intern. Med."},{"key":"ref_25","first-page":"242","article-title":"Multifactorial risk index for predicting postoperative respiratory failure in men after major noncardiac surgery","volume":"232","author":"Arozullah","year":"2000","journal-title":"The National Veterans Administration Surgical Quality Improvement Program. Ann. Surg."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1016\/j.jamcollsurg.2007.02.070","article-title":"Multivariable predictors of postoperative respiratory failure after general and vascular surgery: Results from the patient safety in surgery study","volume":"204","author":"Johnson","year":"2007","journal-title":"J. Am. Coll. Surg."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1164\/rccm.200207-670SO","article-title":"Ischemia-reperfusion induced lung injury","volume":"167","author":"Liu","year":"2003","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1097\/01.CCM.0000124875.98492.11","article-title":"Pulmonary injury follows systemic inflammatory reaction in infrarenal aortic surgery","volume":"32","author":"Adembri","year":"2004","journal-title":"Crit. Care Med."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"H1283","DOI":"10.1152\/ajpheart.00251.2010","article-title":"Lung ischemia-reperfusion injury: A molecular and clinical view on a complex pathophysiological process","volume":"299","author":"Gielis","year":"2010","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1053\/j.jvca.2016.11.013","article-title":"Associated risk factors and complications in vascular surgery patients requiring unplanned postoperative reintubation","volume":"31","author":"Brovman","year":"2017","journal-title":"J. Cardiothorac. Vasc. Anesth."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.jclinane.2015.12.038","article-title":"Incidence and risk factors for early postoperative reintubations","volume":"31","author":"Tillquist","year":"2016","journal-title":"J. Clin. Anesth."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1016\/j.jvs.2011.04.054","article-title":"Results of endovascular aortic aneurysm repair with general, regional and local\/monitored anesthesia care in the American College of Surgeons National Surgical Quality Improvement Program database","volume":"54","author":"Edwards","year":"2011","journal-title":"J. Vasc. Surg."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/j.anclin.2014.05.007","article-title":"Optimal perioperative medical management of the vascular surgery patient","volume":"32","author":"Singh","year":"2014","journal-title":"Anesthesiol. Clin."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1378\/chest.128.2.821","article-title":"Nasal-continuous positive airway pressure reduces pulmonary morbidity and length of hospital stay following thoracoabdominal aortic surgery","volume":"128","author":"Buhl","year":"2005","journal-title":"Chest"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/j.mcna.2013.05.008","article-title":"Patients with vascular disease","volume":"97","author":"Manley","year":"2013","journal-title":"Med. Clin. N. Am."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"2305","DOI":"10.1681\/ASN.2009020171","article-title":"Measured GFR as a confirmatory test for estimated GFR","volume":"20","author":"Stevens","year":"2009","journal-title":"J. Am. Soc. Nephrol."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1038\/ki.2013.243","article-title":"Comment on \u201cKDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease\u201d","volume":"84","author":"Andrassy","year":"2013","journal-title":"Kidney Int."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/S0741-5214(97)70006-5","article-title":"Renal failure after thoracoabdominal aortic surgery","volume":"26","author":"Kashyap","year":"1997","journal-title":"J. Vasc. Surg."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1097\/00000658-199404000-00011","article-title":"Risk assessment of acute renal failure after thoracoabdominal aortic aneurysm surgery","volume":"219","author":"Schepens","year":"1994","journal-title":"Ann. Surg."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.ejvs.2011.11.018","article-title":"What are the risk factors for renal failure following open elective abdominal aortic aneurysm repair?","volume":"43","author":"Grant","year":"2012","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"197.e204","DOI":"10.1053\/ejvs.2001.1422","article-title":"Literature review of surgical management of abdominal aortic aneurysm","volume":"22","author":"Hallin","year":"2001","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"843.e8","DOI":"10.1016\/S0140-6736(04)16979-1","article-title":"Comparison of endovascular aneurysm repair with open repair in patients with abdominal aortic aneurysm (EVAR trial 1), 30-day operative mortality results: Randomized controlled trial","volume":"364","author":"Greenhalgh","year":"2004","journal-title":"Lancet"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1145.e54","DOI":"10.1067\/mva.2002.123686","article-title":"Openinfrarenal abdominal aortic aneurysm repair: The Cleveland Clinic experience from 1989 to 1998","volume":"35","author":"Hertzer","year":"2002","journal-title":"J. Vasc. Surg."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"106.e1","DOI":"10.1016\/j.avsg.2009.09.008","article-title":"National outcomes after open repair of abdominal aortic aneurysms with visceral or renal bypass","volume":"24","author":"Martin","year":"2010","journal-title":"Ann. Vasc. Surg."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1808.e16","DOI":"10.1007\/s00134-006-0308-1","article-title":"Incidence, risk factors and prognosis of changes in serum creatinine early after aortic abdominal surgery","volume":"32","author":"Ellenberger","year":"2006","journal-title":"Intensive Care Med."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"323.e7","DOI":"10.1053\/ejvs.1999.0893","article-title":"Outcome in patients requiringrenal replacement therapy after surgery for ruptured and non-ruptured aneurysm of the abdominal aorta","volume":"18","author":"Braams","year":"1999","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1007\/s11886-013-0462-3","article-title":"Management of symptomatic carotid disease in 2014","volume":"16","author":"Litsky","year":"2014","journal-title":"Curr. Cardiol. Rep."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/j.jvs.2014.04.072","article-title":"Acute kidney injury defined according to the \u2018Risk\u2019, \u2018Injury\u2019, \u2018Failure\u2019, \u2018Loss\u2019, and \u2018End-stage\u2019 (RIFLE) criteria after repair for a ruptured abdominal aortic aneurysm","volume":"60","author":"Legemate","year":"2014","journal-title":"J. Vasc. Surg."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1053\/svas.2001.27877","article-title":"Renal complications with aortic surgery","volume":"14","author":"Cherr","year":"2001","journal-title":"Semin. Vasc. Surg."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.avsg.2010.12.030","article-title":"Comparative predictors of mortality for endovascular and open repair of ruptured infrarenal abdominal aortic aneurysms","volume":"25","author":"Sarac","year":"2011","journal-title":"Ann. Vasc. Surg."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"326","DOI":"10.23736\/S0021-9509.20.11745-2","article-title":"Kidney protection in thoracoabdominal aortic aneurysm surgery","volume":"62","author":"Loschi","year":"2021","journal-title":"J. Cardiovasc. Surg."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jvs.2011.07.031","article-title":"Updated Society for Vascular Surgery guidelines for management of extracranial carotid disease","volume":"54","author":"Ricotta","year":"2011","journal-title":"J. Vasc. Surg."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1016\/S0003-4975(01)03575-5","article-title":"Renal perfusion during thoracoabdominal aortic operations: Cold crystalloid is superior to normothermic blood","volume":"73","author":"Koksoy","year":"2002","journal-title":"Ann. Thorac. Surg."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.jvs.2005.11.053","article-title":"Acute renal failure after endovascular vs open repair of abdominal aortic aneurysm","volume":"43","author":"Wald","year":"2006","journal-title":"J. Vasc. Surg."},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"EVAR Trial Participants (2005). Endovascular aneurysm repair versus open repair in patients with abdominal aortic aneurysm (EVAR trial 1): Randomised controlled trial. Lancet, 365, 2179\u20132186.","DOI":"10.1016\/S0140-6736(05)66627-5"},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"EVAR Trial Participants (2005). Endovascular aneurysm repair and outcome in patients unfit for open repair of abdominal aortic aneurysm (EVAR trial 2): Randomised controlled trial. Lancet, 365, 2187\u20132192.","DOI":"10.1016\/S0140-6736(05)66628-7"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1001\/jama.2009.1426","article-title":"Outcomes following endovascular vs open repair of abdominal aortic aneurysm: A random-ized trial","volume":"302","author":"Lederle","year":"2009","journal-title":"JAMA"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.jvs.2004.12.048","article-title":"Early outcomes of endovascular versus open abdominal aortic aneurysm repair in the National Surgical Quality Improvement Program-Private Sector (NSQIP-PS)","volume":"41","author":"Hua","year":"2005","journal-title":"J. Vasc. Surg."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1002\/bjs.9280","article-title":"Renal function 5 years after open and endo-vascular aortic aneurysm repair from a random-ized trial","volume":"100","author":"Vervloet","year":"2013","journal-title":"Br. J. Surg."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.avsg.2012.05.006","article-title":"Risk factors and impact of proximal fixation on acute and chronic renal dysfunction after endovascular aortic aneurysm repair using glomerular filtration rate criteria","volume":"27","author":"Pisimisis","year":"2013","journal-title":"Ann. Vasc. Surg."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1583\/12-4104MR2.1","article-title":"Acute kidney injury after endovascular repair of abdominal aortic aneurysm","volume":"20","author":"Saratzis","year":"2013","journal-title":"J. Endovasc. Ther."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1583\/07-2299.1","article-title":"Renal consequences of endovascular abdominal aortic aneurysm repair","volume":"15","author":"Walsh","year":"2008","journal-title":"J. Endovasc. Ther."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.suc.2021.05.020","article-title":"Management of Postoperative Complications Following Endovascular Aortic Aneurysm Repair","volume":"101","author":"Qrareya","year":"2021","journal-title":"Surg. Clin. N. Am."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1016\/j.jvs.2014.01.007","article-title":"Epidemiology of aortic aneurysm repair in the United States from 2000 to 2010","volume":"59","author":"Dua","year":"2014","journal-title":"J. Vasc. Surg."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1016\/j.jvs.2016.04.009","article-title":"Renal dysfunction and the associated decrease in survival after elective endovascular an-eurysm repair","volume":"64","author":"Zarkowsky","year":"2016","journal-title":"J. Vasc. Surg."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/j.ejvs.2021.08.033","article-title":"Editor\u2019s choice\u2013Pre-Operative Moderate to Severe Chronic Kidney Disease is associated with worse short-term and mid-term outcomes in patients undergoing fenestrated-branched endovascular aortic repair","volume":"62","author":"Wanhainen","year":"2021","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1097\/SLA.0000000000002485","article-title":"Biomarker-guided intervention to prevent acute kidney injury after major surgery: The prospective randomized BigpAK study","volume":"267","author":"Jauch","year":"2018","journal-title":"Ann. Surg."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1038\/mi.2015.90","article-title":"A secretory leukocyte protease inhibitor variant with improved activity against lung infection","volume":"9","author":"Camper","year":"2016","journal-title":"Mucosal. Immunol."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"33648","DOI":"10.1074\/jbc.M203710200","article-title":"Secretory leucoprotease inhibitor prevents lipopolysaccharide-induced IKappaBalpha degradation without affecting phosphorylation or ubiquitina","volume":"277","author":"Taggart","year":"2022","journal-title":"ation. J. Biol. Chem."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"F767","DOI":"10.1152\/ajprenal.00683.2016","article-title":"MIF-2\/D-Dt enhances proximal tubular cell regeneration through SLPI- and AFT4-dependent mechanisms","volume":"313","author":"Ochi","year":"2017","journal-title":"Am. J. Physiol. Ren. Physiol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"3453","DOI":"10.1038\/s41598-020-60482-9","article-title":"SLPI\u2013A biomarker of acute kidney injury after open and endovascular thoracoabnominal aortic aneurysm (TAAA) repair","volume":"10","author":"Averdunk","year":"2020","journal-title":"Sci Rep."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1177\/1089253211424224","article-title":"Neurological Complications of Thoracic Endovascular Aortic Repair","volume":"15","author":"Ullery","year":"2011","journal-title":"Semin. Cardiothorac. Vasc. Anesthesia"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.ejvs.2018.09.007","article-title":"Outcomes after one stage versus two stage open repair of Type II thoraco-abdominal aortic aneurysms","volume":"57","author":"Gombert","year":"2019","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1161\/CIRCULATIONAHA.108.769695","article-title":"Contemporary analysis of descending thoracic and thoracoabdominal aneurysm repair: A comparison of endovascular and open techniques","volume":"118","author":"Greenberg","year":"2008","journal-title":"Circulation"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1053\/j.jvca.2021.06.024","article-title":"Spinal cord protection for thoracoabdominal aortic surgery","volume":"36","author":"Miller","year":"2022","journal-title":"J. Cardiothorac. Vasc. Anesth."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"3S","DOI":"10.1016\/j.jvs.2010.06.137","article-title":"Outcomes in open repair of the thoracic and thoracoabdominal aorta","volume":"52","author":"Acher","year":"2010","journal-title":"J. Vasc. Surg."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"e266","DOI":"10.1161\/CIR.0b013e3181d47d48","article-title":"2010 ACCF\/AHA\/AATS\/ACR\/ASA\/SCA\/SCAI\/SIR\/STS\/SVM guidelines for the diagnosis and management of patients with Thoracic Aortic Disease","volume":"121","author":"Hiratzka","year":"2010","journal-title":"Circulation"},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1053\/j.jvca.2014.06.024","article-title":"Complications of spinal fluid drainage in thoracic and thoracoabdominal aortic aneurysm surgery in 724 patients treated from 1987 to 2013","volume":"29","author":"Wynn","year":"2015","journal-title":"J. Cardiothorac. Vasc. Anesth."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1016\/j.bja.2017.12.045","article-title":"Cerebrospinal-fluid drain-related complications in patients undergoing open and endovascular repairs of thoracic and thoraco-abdominal aortic pathologies: A systematic review and meta-analysis","volume":"120","author":"Rong","year":"2018","journal-title":"Br. J. Anaesth."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1016\/j.jvs.2019.06.210","article-title":"Cerebrospinal fluid drainage complications during first stage and comple-tion fenestrated-branched endovascular aortic repair","volume":"71","author":"Karkkainen","year":"2020","journal-title":"J. Vasc. Surg."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1067\/mva.2002.122024","article-title":"Cerebrospinal fluid drainage reduces paraplegia after thoracoabdominal aortic aneurysm repair: Results of a randomized clinical trial","volume":"35","author":"Coselli","year":"2002","journal-title":"J. Vasc. Surg."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"55S","DOI":"10.1016\/j.jvs.2020.05.076","article-title":"Society for Vascular Surgery clinical practice guidelines of thoracic endovascular aortic repair for descending thoracic aortic aneurysms","volume":"73","author":"Upchurch","year":"2021","journal-title":"J. Vasc. Surg."},{"key":"ref_83","first-page":"5","article-title":"The treatment of spinal cord ischemia following thoracic endovascular aortic repair","volume":"6","author":"Mullen","year":"2007","journal-title":"Neurocrit. Care"},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/j.jvs.2010.05.008","article-title":"Open and endovascular repair of type B aortic dissection in the Nationwide Inpatient Sample","volume":"52","author":"Sachs","year":"2010","journal-title":"J. Vasc. Surg."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.ejvs.2018.02.002","article-title":"Spinal Cord Ischaemia in Endovascular Thoracic and Thoraco-abdominal Aortic Repair: Review of Preventive Strategies","volume":"55","author":"Dijkstra","year":"2018","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.ejvs.2014.12.034","article-title":"Short-term outcome of spinal cord ischemia after endovascular repair of thoracoabdominal aortic aneurysms","volume":"49","author":"Dias","year":"2015","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/j.jvs.2005.06.011","article-title":"Evidence for early nasogastric tube removal after infrarenal aortic surgery: A randomized trial","volume":"42","author":"Goueffic","year":"2005","journal-title":"J. Vasc. Surg."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"S26","DOI":"10.1016\/j.surg.2007.06.021","article-title":"Management of hemostasis in vascular surgery","volume":"142","author":"Untch","year":"2007","journal-title":"Surgery"},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1053\/j.jvca.2017.04.047","article-title":"Pro: Activated clotting time should be monitored during heparinization for vascular surgery","volume":"32","author":"Goldhammer","year":"2018","journal-title":"J. Cardiothorac. Vasc. Anesth."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1007\/s00134-006-0349-5","article-title":"Results from the International Conference of Experts on Intra-abdominal Hypertension and Abdominal Compartment Syndrome","volume":"32","author":"Malbrain","year":"2006","journal-title":"I. Definitions. Intensive Care Med."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1007\/s00134-007-0592-4","article-title":"Results from the International Conference of Experts on Intra-abdominal Hypertension and Abdominal Compartment Syndrome","volume":"33","author":"Cheatham","year":"2007","journal-title":"II. Recommendations. Intensive Care Med."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1001\/archsurg.2009.70","article-title":"Ischemic colitis after endovascular aortoiliac aneurysm repair: A 10-year retrospective study","volume":"144","author":"Miller","year":"2009","journal-title":"Arch. Surg."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"S138","DOI":"10.21037\/cdt.2017.09.17","article-title":"Complications of endovascular aneurysm repair of the thoracic and abdominal aorta: Evaluation and management","volume":"8","author":"Daye","year":"2018","journal-title":"Cardiovasc. Diagn. Ther."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.jvs.2003.09.043","article-title":"Outcomes of secondary interventions after abdominal aortic aneurysm endovascular repair","volume":"39","author":"Becquemin","year":"2004","journal-title":"J. Vasc. Surg."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.jvs.2008.03.040","article-title":"Colonic ischemia complicating open vs endovascular abdominal aortic aneurysm repair","volume":"48","author":"Perry","year":"2008","journal-title":"J. Vasc. Surg."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.avsg.2020.01.102","article-title":"Occlusion of the celiac artery during endovascular thoracoabdominal aortic aneurysm repair is associated with increased perioperative morbidity and mortality","volume":"66","author":"King","year":"2020","journal-title":"Ann. Vasc. Surg."},{"key":"ref_97","doi-asserted-by":"crossref","unstructured":"American Society of Anesthesiologists Task Force on Perioperative Blood Management (2015). Practice Guidelines for Perioperative Blood Management: An Updated Report by the American Society of Anesthesiologists Task Force on Perioperative Blood Management. Anesthesiology, 122, 241\u2013275.","DOI":"10.1097\/ALN.0000000000000463"},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1093\/ejcts\/ezx325","article-title":"2017 EACTS\/EACTA Guidelines on patient blood management for adult cardiac surgery","volume":"53","author":"Boer","year":"2018","journal-title":"Eur. J. CardioThorac. Surg."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.ejvs.2017.07.006","article-title":"Individual differences in heparin sensitivity and their effect on heparin anticoagulation during arterial vascular surgery","volume":"54","author":"Veerhoek","year":"2017","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/j.anclin.2014.05.003","article-title":"Considerations for patients undergoing endovascular abdominal aortic aneurysm repair","volume":"32","author":"Ullery","year":"2014","journal-title":"Anesthesiol. Clin."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S1053-0770(97)90203-2","article-title":"Disseminated intravascular coagulation associated with acute ischemic hepatitis after elective aortic aneurysm repair: Comparative analysis of 10 cases","volume":"11","author":"Levy","year":"1997","journal-title":"J. Cardiothorac. Vasc. Anesth."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1093\/bja\/aew270","article-title":"Management of bleeding in vascular surgery","volume":"117","author":"Chee","year":"2016","journal-title":"Br. J. Anaesth."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1111\/anae.12914","article-title":"The pathogenesis of traumatic coagulopathy","volume":"70","author":"Cap","year":"2015","journal-title":"Anaesthesia"},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1097\/SHK.0000000000000088","article-title":"An update on the coagulopathy of trauma","volume":"41","author":"Maegele","year":"2014","journal-title":"Shock"},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1097\/01.sla.0000256862.79374.31","article-title":"Acute traumatic coagulopathy: Initiated by hypoperfusion: Modulated through the protein C path-way?","volume":"245","author":"Brohi","year":"2007","journal-title":"Ann. Surg."}],"container-title":["Journal of Personalized Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4426\/12\/8\/1351\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:13:31Z","timestamp":1760141611000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4426\/12\/8\/1351"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,22]]},"references-count":105,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2022,8]]}},"alternative-id":["jpm12081351"],"URL":"https:\/\/doi.org\/10.3390\/jpm12081351","relation":{},"ISSN":["2075-4426"],"issn-type":[{"value":"2075-4426","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,22]]}}}