{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T03:02:44Z","timestamp":1787799764060,"version":"build-2784847793"},"reference-count":42,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T00:00:00Z","timestamp":1664150400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Health and Medical Research Council (NHMRC)","award":["1129822"],"award-info":[{"award-number":["1129822"]}]},{"name":"National Health and Medical Research Council (NHMRC)","award":["ANZMTG 03.17"],"award-info":[{"award-number":["ANZMTG 03.17"]}]},{"name":"National Health and Medical Research Council (NHMRC)","award":["1147843"],"award-info":[{"award-number":["1147843"]}]},{"name":"National Health and Medical Research Council (NHMRC)","award":["2008454"],"award-info":[{"award-number":["2008454"]}]},{"name":"Melanoma and Skin Cancer Trials","award":["1129822"],"award-info":[{"award-number":["1129822"]}]},{"name":"Melanoma and Skin Cancer Trials","award":["ANZMTG 03.17"],"award-info":[{"award-number":["ANZMTG 03.17"]}]},{"name":"Melanoma and Skin Cancer Trials","award":["1147843"],"award-info":[{"award-number":["1147843"]}]},{"name":"Melanoma and Skin Cancer Trials","award":["2008454"],"award-info":[{"award-number":["2008454"]}]},{"name":"Research Training Program (RTP) Stipend Scholarship","award":["1129822"],"award-info":[{"award-number":["1129822"]}]},{"name":"Research Training Program (RTP) Stipend Scholarship","award":["ANZMTG 03.17"],"award-info":[{"award-number":["ANZMTG 03.17"]}]},{"name":"Research Training Program (RTP) Stipend Scholarship","award":["1147843"],"award-info":[{"award-number":["1147843"]}]},{"name":"Research Training Program (RTP) Stipend Scholarship","award":["2008454"],"award-info":[{"award-number":["2008454"]}]},{"name":"Melanoma Institute Australia Postgraduate Research Scholarship","award":["1129822"],"award-info":[{"award-number":["1129822"]}]},{"name":"Melanoma Institute Australia Postgraduate Research Scholarship","award":["ANZMTG 03.17"],"award-info":[{"award-number":["ANZMTG 03.17"]}]},{"name":"Melanoma Institute Australia Postgraduate Research Scholarship","award":["1147843"],"award-info":[{"award-number":["1147843"]}]},{"name":"Melanoma Institute Australia Postgraduate Research Scholarship","award":["2008454"],"award-info":[{"award-number":["2008454"]}]},{"name":"NHMRC","award":["1129822"],"award-info":[{"award-number":["1129822"]}]},{"name":"NHMRC","award":["ANZMTG 03.17"],"award-info":[{"award-number":["ANZMTG 03.17"]}]},{"name":"NHMRC","award":["1147843"],"award-info":[{"award-number":["1147843"]}]},{"name":"NHMRC","award":["2008454"],"award-info":[{"award-number":["2008454"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>Personalized polygenic risk information may be used to guide risk-based melanoma prevention and early detection at a population scale, but research on communicating this information is limited. This mixed-methods study aimed to assess the acceptability of a genetic counselor (GC) phone call in communicating polygenic risk information in the Melanoma Genomics Managing Your Risk randomized controlled trial. Participants (n = 509) received personalized melanoma polygenic risk information, an educational booklet on melanoma prevention, and a GC phone call, which was audio-recorded. Participants completed the Genetic Counseling Satisfaction Survey 1-month after receiving their risk information (n = 346). A subgroup took part in a qualitative interview post-study completion (n = 20). Survey data were analyzed descriptively using SPSS, and thematic analysis of the qualitative data was conducted using NVivo 12.0 software. The survey showed a high level of acceptability for the GC phone call (mean satisfaction score overall: 4.3 out of 5, standard deviation (SD): 0.6) with differences according to gender (mean score for women: 4.4, SD: 0.6 vs. men: 4.2, SD: 0.7; p = 0.005), health literacy (lower literacy: 4.1, SD: 0.8; average: 4.3, SD: 0.6; higher: 4.4, SD: 0.6: p = 0.02) and polygenic risk group (low risk: 4.5, SD: 0.5, SD: average: 4.3, SD: 0.7, high: 4.3, SD: 0.7; p = 0.03). During the GC phone calls, the discussion predominately related to the impact of past sun exposure on personal melanoma risk. Together our findings point to the importance of further exploring educational and support needs and preferences for communicating personalized melanoma risk among population subgroups, including diverse literacy levels.<\/jats:p>","DOI":"10.3390\/jpm12101581","type":"journal-article","created":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T05:20:58Z","timestamp":1664169658000},"page":"1581","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Communicating Personal Melanoma Polygenic Risk Information: Participants\u2019 Experiences of Genetic Counseling in a Community-Based Study"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5712-220X","authenticated-orcid":false,"given":"Amelia K.","family":"Smit","sequence":"first","affiliation":[{"name":"The Daffodil Centre, The University of Sydney, A Joint Venture with Cancer Council NSW, Sydney 2000, Australia"},{"name":"Melanoma Institute Australia, The University of Sydney, Sydney 2000, Australia"},{"name":"Sydney School of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney 2000, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Espinoza","sequence":"additional","affiliation":[{"name":"NHMRC Clinical Trials Centre, Faculty of Medicine and Health, The University of Sydney, Sydney 2000, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgina L.","family":"Fenton","sequence":"additional","affiliation":[{"name":"The Daffodil Centre, The University of Sydney, A Joint Venture with Cancer Council NSW, Sydney 2000, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judy","family":"Kirk","sequence":"additional","affiliation":[{"name":"Westmead Clinical School and Westmead Institute for Medical Research, Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney 2000, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica S.","family":"Innes","sequence":"additional","affiliation":[{"name":"Discipline of Genetic Counselling, Graduate School of Health, University of Technology Sydney, Sydney 2000, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3405-2151","authenticated-orcid":false,"given":"Michael","family":"McGovern","sequence":"additional","affiliation":[{"name":"Maastricht University, 6221 BS Maastricht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharne","family":"Limb","sequence":"additional","affiliation":[{"name":"Parkville Familial Cancer Centre, Peter MacCallum Cancer Centre and Royal Melbourne Hospitals, Melbourne 3000, Australia"},{"name":"Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne 3000, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the Managing Your Risk Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6650-9702","authenticated-orcid":false,"given":"Erin","family":"Turbitt","sequence":"additional","affiliation":[{"name":"Discipline of Genetic Counselling, Graduate School of Health, University of Technology Sydney, Sydney 2000, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5331-6370","authenticated-orcid":false,"given":"Anne E.","family":"Cust","sequence":"additional","affiliation":[{"name":"The Daffodil Centre, The University of Sydney, A Joint Venture with Cancer Council NSW, Sydney 2000, Australia"},{"name":"Melanoma Institute Australia, The University of Sydney, Sydney 2000, Australia"},{"name":"Sydney School of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney 2000, 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