{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:25:40Z","timestamp":1768436740961,"version":"3.49.0"},"reference-count":23,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2022,10,10]],"date-time":"2022-10-10T00:00:00Z","timestamp":1665360000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"University of Ulsan College of Medicine","award":["NRF-2022R1F1A1073895"],"award-info":[{"award-number":["NRF-2022R1F1A1073895"]}]},{"name":"University of Ulsan College of Medicine","award":["2021IP0060"],"award-info":[{"award-number":["2021IP0060"]}]},{"name":"University of Ulsan College of Medicine","award":["2022IP0066"],"award-info":[{"award-number":["2022IP0066"]}]},{"name":"Asan Institute for Life Sciences","award":["NRF-2022R1F1A1073895"],"award-info":[{"award-number":["NRF-2022R1F1A1073895"]}]},{"name":"Asan Institute for Life Sciences","award":["2021IP0060"],"award-info":[{"award-number":["2021IP0060"]}]},{"name":"Asan Institute for Life Sciences","award":["2022IP0066"],"award-info":[{"award-number":["2022IP0066"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>We aimed to investigate the changes in higher-order aberrations (HOAs) after wearing orthokeratology (OK) lenses in myopic patients. The study included 15 eyes from ten myopic patients, whose refractive error was myopia less than \u22124.5 diopters (D) and astigmatism less than 1.5 D. Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA) were measured, and Zywave\u00ae aberrometry was performed at baseline and 1, 3, and 6 months following OK lens wear. The mean age was 11.5 years (range: 9\u201315 years). There was a significant improvement in UCVA (p \u2264 0.001) and a decrease in the spherical equivalent measured with auto-refraction at 6 months (p \u2264 0.001). Total HOAs significantly increased after OK lens wear (p \u2264 0.001), with spherical aberration increasing approximately 3.9-fold (p = 0.05). Spherical aberration demonstrated statistically significant positive correlations with the change in spherical equivalent at 3 and 6 months (p = 0.007 and 0.003, respectively). After wearing properly prescribed OK lens, all subjects had significantly improved UCVA and decreased myopic spherical equivalent, with increased total HOAs and positive spherical aberration at 1 month, and the changes were maintained at 6 months. Serially checked spherical aberration could evaluate the anti-myopia effect of the orthokeratology lens in children.<\/jats:p>","DOI":"10.3390\/jpm12101686","type":"journal-article","created":{"date-parts":[[2022,10,9]],"date-time":"2022-10-09T23:31:43Z","timestamp":1665358303000},"page":"1686","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Serially Checked Spherical Aberration Can Evaluate the Anti-Myopia Effect of Orthokeratology Lens in Children"],"prefix":"10.3390","volume":"12","author":[{"given":"In-Kyun","family":"Hahn","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, University of Ulsan College of Medicine, Asan Medical Center, 88, Olympic-Ro 43-Gil, Songpa-gu, Seoul 05505, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donghan","family":"Lee","sequence":"additional","affiliation":[{"name":"University of Ulsan College of Medicine, 88, Olympic-Ro 43-Gil, Songpa-gu, Seoul 05505, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong-Ho","family":"Lee","sequence":"additional","affiliation":[{"name":"Bitsarang Eye Clinic, Prince Building, 492, Nohae-ro, Nowon-gu, Seoul 01751, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7225-6580","authenticated-orcid":false,"given":"Hun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of Ulsan College of Medicine, Asan Medical Center, 88, Olympic-Ro 43-Gil, Songpa-gu, Seoul 05505, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hungwon","family":"Tchah","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of Ulsan College of Medicine, Asan Medical Center, 88, Olympic-Ro 43-Gil, Songpa-gu, Seoul 05505, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8571-8350","authenticated-orcid":false,"given":"Jae-Yong","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of Ulsan College of Medicine, Asan Medical Center, 88, Olympic-Ro 43-Gil, Songpa-gu, Seoul 05505, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,10,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1111\/j.1444-0938.2011.00616.x","article-title":"Toric orthokeratology for high myopic and astigmatic subjects for myopic control","volume":"95","author":"Chen","year":"2012","journal-title":"Clin. 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