{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T17:38:00Z","timestamp":1793813880805,"version":"4.6.1"},"reference-count":79,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2022,12,19]],"date-time":"2022-12-19T00:00:00Z","timestamp":1671408000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>Cleft lip and cleft palate has one of the highest incidences in the malformations of the oral cavity, that varies between populations. The background underlying the issue of cleft lip and palate is multifactorial and greatly depends on the genetic factors and environmental factors. The aim of this nonsystematic narrative review is to present the cleft palate and or lip pediatric population as target for interdisciplinary treatment. The purpose of this narrative review is to sum up the modern knowledge on the treatment of patients with clefts, as well as to highlight the importance of the great need for cooperation between different dental specialists along with medical professionals such as oral surgeons, prosthodontists, orthodontists along with medical professions such as pediatricians, speech therapists and phoniatrics, and laryngologist.<\/jats:p>","DOI":"10.3390\/jpm12122089","type":"journal-article","created":{"date-parts":[[2022,12,19]],"date-time":"2022-12-19T09:31:01Z","timestamp":1671442261000},"page":"2089","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":79,"title":["Current Concepts and Challenges in the Treatment of Cleft Lip and Palate Patients\u2014A Comprehensive Review"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2817-1445","authenticated-orcid":false,"given":"Anna","family":"Paradowska-Stolarz","sequence":"first","affiliation":[{"name":"Division of Dentofacial Anomalies, Department of Orthodontics and Dentofacial Orhopedics, Wroclaw Medical University, Krakowska 26, 52-425 Wroc\u0142aw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5754-0284","authenticated-orcid":false,"given":"Marcin","family":"Mikulewicz","sequence":"additional","affiliation":[{"name":"Division of Dentofacial Anomalies, Department of Orthodontics and Dentofacial Orhopedics, Wroclaw Medical University, Krakowska 26, 52-425 Wroc\u0142aw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4745-2560","authenticated-orcid":false,"given":"Irena","family":"Du\u015b-Ilnicka","sequence":"additional","affiliation":[{"name":"Oral Pathology Department, Wroclaw Medical University, ul. Krakowska 26, 52-425 Wroc\u0142aw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1016\/S0140-6736(09)60695-4","article-title":"Cleft lip and palate","volume":"374","author":"Mossey","year":"2009","journal-title":"Lancet"},{"key":"ref_2","first-page":"145","article-title":"Current concepts on cleft lip and palate etiology","volume":"33","author":"Supplement","year":"2019","journal-title":"J. Biol. Regul. Homeost. Agents"},{"key":"ref_3","first-page":"15","article-title":"Cleft lip and palate in a Brazilian subpopulation","volume":"5","author":"Cuozzo","year":"2013","journal-title":"J. Int. 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