{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T23:34:59Z","timestamp":1781048099770,"version":"3.54.1"},"reference-count":27,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T00:00:00Z","timestamp":1672272000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>Chronic otitis media (COM) is a persistent inflammation of the middle ear. COM often requires surgical management and represents one of the most disabling pathologies in the field of otolaryngology, not only due to hearing loss but also because recurrent otorrhea seriously affects the quality of life (QoL) of patients. The COMOT-15 questionnaire is a reliable, valid and sensitive tool for measuring the QoL of patients with COM. The aim of this study was to evaluate QoL by using the Italian version of the COMOT-15 in COM patients undergoing surgery based on age and different operation techniques. This observational retrospective study involved fifty-two consecutive patients undergoing surgical treatment for COM according to Nadol criteria. Preoperatively (T0) and 12 months after surgery (T1) patients underwent clinical examination, imaging, the Italian version of the COMOT-15 and pure tone audiometry. After surgery, we observed an improvement of QoL in 84.6% of the population. The COMOT-15 overall score, ear symptoms and hearing subscores showed significantly better ratings after surgery in the whole analyzed group. However, the separate analysis of patients operated with open techniques and closed techniques showed a significant improvement in ear symptoms subscore in both groups and a significant improvement in hearing subscore and mental health subscore only in patients operated on with closed techniques. Moreover, we observed a positive correlation between age and \u0394-COMOT. This study shows the crucial role of a reliable and suitable questionnaire such as the COMOT-15 in evaluating COM patients, including clinical symptoms, functional and psychological impairments and highlighting a positive correlation between age and COMOT-15 results.<\/jats:p>","DOI":"10.3390\/jpm13010074","type":"journal-article","created":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T02:59:01Z","timestamp":1672282741000},"page":"74","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Quality of Life Assessment of Chronic Otitis Media Patients Following Surgery"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8968-4725","authenticated-orcid":false,"given":"Michele","family":"Cavaliere","sequence":"first","affiliation":[{"name":"ENT Section, Department of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples, Federico II. Pansini Street n.5, 80131 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonella Miriam","family":"Di Lullo","sequence":"additional","affiliation":[{"name":"ENT Section, Department of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples, Federico II. Pansini Street n.5, 80131 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pasquale","family":"Capriglione","sequence":"additional","affiliation":[{"name":"ENT Section, Department of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples, Federico II. Pansini Street n.5, 80131 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaetano","family":"Motta","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology, Head and Neck Surgery Unit, Department of Mental and Physical Health and Preventive, Medicine, Universit\u00e0 Degli Studi Della Campania Luigi Vanvitelli, 80131 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7389-2033","authenticated-orcid":false,"given":"Elena","family":"Cantone","sequence":"additional","affiliation":[{"name":"ENT Section, Department of Neuroscience, Reproductive and Odontostomatological Sciences, University of Naples, Federico II. Pansini Street n.5, 80131 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"365","DOI":"10.5152\/iao.2022.21428","article-title":"Hearing Rehabilitation of Patients with Chronic Otitis Media: A Discussion of Current State of Knowledge and Research Priorities","volume":"18","author":"Backous","year":"2022","journal-title":"J. Int. Adv. Otol."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Jotic, A.D., Opankovic, A.M., Radin, Z.Z., Cvorovic, L., Vujovic, K.R.S., Krejovic-Trivic, S.B., Bukurov, B.M., Milicic, B.R., and Stojanovic, J.D. (2022). Symptoms of depression, anxiety and stress in patients with chronic otitis media. PLoS ONE, 17.","DOI":"10.1371\/journal.pone.0270793"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"3217","DOI":"10.1007\/s00405-020-06397-7","article-title":"Impact of depressive disorders on quality of life after middle ear surgery in patients with chronic otitis media","volume":"278","author":"Lailach","year":"2020","journal-title":"Eur. Arch. Oto-Rhino-Laryngol."},{"key":"ref_4","unstructured":"World Health Organization (2004). Chronic Suppurative Otitis Media: Burden of Illness and Management Options."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"e1507","DOI":"10.1097\/MAO.0000000000003299","article-title":"Impact of Hearing Disability and Ear Discharge on Quality-of-Life in Patients with Chronic Otitis Media: Data from the Multinational Collaborative COMQ-12 Study","volume":"42","author":"Phillips","year":"2021","journal-title":"Otol. Neurotol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1007\/s00106-008-1870-3","article-title":"Entwicklung und Validierung des Chronic Otitis Media Outcome Test 15 (COMOT-15)","volume":"57","author":"Baumann","year":"2009","journal-title":"HNO"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1097\/00005537-200003002-00009","article-title":"Outcomes Assessment for Chronic Otitis Media: The Chronic Ear Survey","volume":"110","author":"Nadol","year":"2000","journal-title":"Laryngoscope"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"293","DOI":"10.14639\/0392-100X-N1998","article-title":"Quality of life after cholesteatoma surgery: Comparison between surgical techniques","volume":"42","author":"Pontillo","year":"2022","journal-title":"Acta Otorhinolaryngol. Ital."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"3073","DOI":"10.1007\/s00405-016-3915-7","article-title":"Development and validation of the Zurich chronic middle ear inventory (ZCMEI-21): An electronic questionnaire for assessing quality of life in patients with chronic otitis media","volume":"273","author":"Ditzen","year":"2016","journal-title":"Eur. Arch. Oto-Rhino-Laryngol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.ijporl.2008.10.030","article-title":"Quality of life in children with chronic suppurative otitis media with or without cholesteatoma","volume":"73","author":"Vlastos","year":"2009","journal-title":"Int. J. Pediatr. Otorhinolaryngol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"3027","DOI":"10.1007\/s00405-019-05591-6","article-title":"Cross-cultural adaption and validation of the Chronic Otitis Media Questionnaire 12 (COMQ-12) in the Italian language","volume":"276","author":"Quaranta","year":"2019","journal-title":"Eur. Arch. Oto-Rhino-Laryngol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1007\/s00106-018-0524-3","article-title":"Aktueller Stand der Lebensqualit\u00e4tsmessung bei Patienten mit chronischer Otitis media und Schallleitungsschwerh\u00f6rigkeit","volume":"66","author":"Lailach","year":"2018","journal-title":"HNO"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1159\/000335927","article-title":"Stapedotomy: Functional Results with Different Diameter Prostheses","volume":"74","author":"Cavaliere","year":"2012","journal-title":"ORL"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1007\/s00405-021-06702-y","article-title":"Comparison of two disease-specific instruments assessing health-related quality of life in patients with chronic otitis media","volume":"279","author":"Mlynski","year":"2021","journal-title":"Eur. Arch. Oto-Rhino-Laryngol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"277","DOI":"10.14639\/0392-100X-N1184","article-title":"Cross-cultural adaptation and Italian validation of chronic otitis media outcome test 15 (COMOT-15)","volume":"41","author":"Cavaliere","year":"2021","journal-title":"Acta Otorhinolaryngol. Ital."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.arcmed.2014.10.005","article-title":"50th anniversary of the Declaration of Helsinki: The double standard was introduced","volume":"45","author":"Hellmann","year":"2014","journal-title":"Arch. Med. Res."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Preciado, D. (2015). Management of chronic suppurative otitis media. Otitis Media: State of the Art Concepts and Treatment, Springer.","DOI":"10.1007\/978-3-319-17888-2"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"108915","DOI":"10.1016\/j.ejrad.2020.108915","article-title":"Apparent diffusion coefficients for predicting primary cholesteatoma risk of recurrence after surgical clearance","volume":"125","author":"Russo","year":"2020","journal-title":"Eur. J. Radiol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"615356","DOI":"10.3389\/fneur.2021.615356","article-title":"Computed-Tomography-Structured Reporting in Middle Ear Opacification: Surgical Results and Clinical Considerations From a Large Retrospective Analysis","volume":"12","author":"Cavaliere","year":"2021","journal-title":"Front. Neurol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"606692","DOI":"10.3389\/fneur.2021.606692","article-title":"Combining Thin-Section Coronal and Axial Diffusion Weighted Imaging: Good Practice in Middle Ear Cholesteatoma Neuroimaging","volume":"12","author":"Russo","year":"2021","journal-title":"Front. Neurol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1007\/s00405-020-05819-w","article-title":"Establishing the minimal clinically important difference (MCID) of the Zurich Chronic Middle Ear Inventory (ZCMEI-21) in patients treated for chronic middle ear disease","volume":"277","author":"Mlynski","year":"2020","journal-title":"Eur. Arch. Oto-Rhino-Laryngol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1001\/archoto.2012.1800","article-title":"Factors Associated With Quality of Life After Ear Surgery in Patients With Chronic Otitis Media","volume":"138","author":"Choi","year":"2012","journal-title":"Arch. Otolaryngol. Neck Surg."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1111\/tmi.12516","article-title":"Quality of life of Nepali patients with ear disease before and after corrective surgery","volume":"20","author":"Maile","year":"2015","journal-title":"Trop. Med. Int. Health"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"2729","DOI":"10.1007\/s00405-020-06002-x","article-title":"Mapping the ChOLE classification to hearing outcomes and disease-specific health-related quality of life","volume":"277","author":"Weiss","year":"2020","journal-title":"Eur. Arch. Oto-Rhino-Laryngol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1007\/s00405-020-05881-4","article-title":"Mastoid cavity obliteration leads to a clinically significant improvement in health-related quality of life","volume":"277","author":"Weiss","year":"2020","journal-title":"Eur. Arch. Oto-Rhino-Laryngol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"53","DOI":"10.14639\/0392-100X-2005","article-title":"Quality of life and functional results in canal wall down vs canal wall up mastoidectomy","volume":"39","author":"Lucidi","year":"2019","journal-title":"Acta Otorhinolaryngol. Ital."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1186\/1477-7525-9-48","article-title":"General and disease-specific quality of life in patients with chronic suppurative otitis media\u2014A prospective study","volume":"9","author":"Baumann","year":"2011","journal-title":"Health Qual. 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