{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T09:29:50Z","timestamp":1787736590829,"version":"build-2784847793"},"reference-count":33,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T00:00:00Z","timestamp":1672272000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Basic Science Research Program through the National Research Foundation of Korea","award":["2021R1F1A1048113"],"award-info":[{"award-number":["2021R1F1A1048113"]}]},{"name":"Basic Science Research Program through the National Research Foundation of Korea","award":["2022-0-00621"],"award-info":[{"award-number":["2022-0-00621"]}]},{"name":"Basic Science Research Program through the National Research Foundation of Korea","award":["HI22C073600"],"award-info":[{"award-number":["HI22C073600"]}]},{"name":"Basic Science Research Program through the National Research Foundation of Korea","award":["2020R1A2C4001842"],"award-info":[{"award-number":["2020R1A2C4001842"]}]},{"name":"Basic Science Research Program through the National Research Foundation of Korea","award":["21C0712L1-11"],"award-info":[{"award-number":["21C0712L1-11"]}]},{"name":"Institute of Information &amp; 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Welfare","award":["2021R1F1A1048113"],"award-info":[{"award-number":["2021R1F1A1048113"]}]},{"name":"Ministry of Science and ICT, the Ministry of Health &amp; Welfare","award":["2022-0-00621"],"award-info":[{"award-number":["2022-0-00621"]}]},{"name":"Ministry of Science and ICT, the Ministry of Health &amp; Welfare","award":["HI22C073600"],"award-info":[{"award-number":["HI22C073600"]}]},{"name":"Ministry of Science and ICT, the Ministry of Health &amp; Welfare","award":["2020R1A2C4001842"],"award-info":[{"award-number":["2020R1A2C4001842"]}]},{"name":"Ministry of Science and ICT, the Ministry of Health &amp; Welfare","award":["21C0712L1-11"],"award-info":[{"award-number":["21C0712L1-11"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>To investigate the association of the oral health parameters with Meniere\u2019s disease in a nationwide population-based longitudinal cohort database. The data of the participants who underwent an oral health screening by dentists in 2003 (n = 2,415,963) were retrieved from the National Health Insurance Database of the Korean National Health Insurance Service. The main outcome was the occurrence of Meniere\u2019s disease, defined as two or more claims of the diagnostic code H810 with a previous audiometric examination. The occurrence of Meniere\u2019s disease was analyzed using a Cox proportional hazard model according to the presence of periodontitis and the oral health examination findings, including missing teeth, the frequency of tooth brushing and dental scaling. Overall, the analysis included 2,240,282 participants. During a median follow-up of 16.7 years, Meniere\u2019s disease developed in 112,106 (5.0%) participants. Poor oral health status was characterized by the presence of periodontitis (adjusted hazard ratio [aHR]: 1.18, 95% confidence interval [CI]: 1.14\u20131.22, p &lt; 0.001) and an increased number of missing teeth (\u226515; aHR: 1.25, 95% CI: 1.18\u20131.32, p &lt; 0.001) was associated with an increased risk of Meniere\u2019s disease. Better oral hygiene behaviors, such as frequent tooth brushing (\u22653 per day; aHR: 0.75, 95% CI: 0.73\u20130.76, p &lt; 0.001) and dental scaling within 1 year (aHR: 0.98, 95% CI: 0.97\u20130.99, p = 0.003) were negatively associated with the occurrence of Meniere\u2019s disease. The presence of periodontitis and an increased number of missing teeth may augment the risk of the occurrence of Meniere\u2019s disease. However, maintaining good oral hygiene through tooth brushing and dental scaling may be associated with a decreased risk of Meniere\u2019s disease. Further studies should confirm the association between oral health and Meniere\u2019s disease.<\/jats:p>","DOI":"10.3390\/jpm13010080","type":"journal-article","created":{"date-parts":[[2022,12,30]],"date-time":"2022-12-30T03:31:17Z","timestamp":1672371077000},"page":"80","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Better Oral Hygiene Is Associated with a Decreased Risk of Meniere\u2019s Disease: A Nationwide Cohort Study"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5297-5059","authenticated-orcid":false,"given":"Jung-Hyun","family":"Park","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Mokdong Hospital, College of Medicine, Seoul 07985, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1672-5730","authenticated-orcid":false,"given":"Jin-Woo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Mokdong Hospital, College of Medicine, Seoul 07985, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3784-312X","authenticated-orcid":false,"given":"Heajung","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Neurology, Seoul Hospital, Ewha Womans University College of Medicine, Seoul 07804, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iksun","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Neurology, Seoul Hospital, Ewha Womans University College of Medicine, Seoul 07804, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9937-762X","authenticated-orcid":false,"given":"Tae-Jin","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Neurology, Seoul Hospital, Ewha Womans University College of Medicine, Seoul 07804, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1111\/jcpe.13304","article-title":"Oral health and gastrointestinal cancer: A nationwide cohort study","volume":"47","author":"Lee","year":"2020","journal-title":"J. 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