{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T04:41:26Z","timestamp":1778820086822,"version":"3.51.4"},"reference-count":52,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2023,3,22]],"date-time":"2023-03-22T00:00:00Z","timestamp":1679443200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>Purpose: A retrospective study is presented to correlate the inter-judge consistency for the different psycho-perceptual parameters of the recently proposed Impression Noise Fluency Voicing (INFVo) perceptual rating scale for substitution voices, and the vocal function as perceived by the patient. Methods: The scale Voice-Related Quality of Life (V-RQoL) and the Self Evaluation of Communication Experiences After Laryngectomy scale (SECEL)\u2014a self-evaluation questionnaire of communicative experience after laryngectomy surgery\u2014were administered to 89 total laryngectomees, subdivided in four groups depending on their type of alaryngeal voice (i.e., tracheoesophageal and esophageal speakers, electro larynx users, voiceless patients), in order to evaluate the impact of the impairment of the phonatory function on the quality of life. Results: No significant differences exist among the various groups on their perception of QoL using subjective questionnaires, whereas the INFVo scale has proven to be a useful tool for the description and analysis of the psychoacoustic characteristics of the vocal signal and a reliable instrument to correctly classify the patients. It is also notable that the judgement of the patients on their own voice and those of the referees are highly significant. Conclusion: Although speech rehabilitation for the acquisition of a substitution voice offers a new way of communication for the laryngectomized patients, nonetheless, their QoL is not significantly related to the type of substitution voice. Therefore, improving the patient\u2019s adaptation to the new phonatory condition is mandatory.<\/jats:p>","DOI":"10.3390\/jpm13030570","type":"journal-article","created":{"date-parts":[[2023,3,23]],"date-time":"2023-03-23T03:07:57Z","timestamp":1679540877000},"page":"570","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Subjective Perception and Psychoacoustic Aspects of the Laryngectomee Voice: The Impact on Quality of Life"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5081-1552","authenticated-orcid":false,"given":"Massimo","family":"Mesolella","sequence":"first","affiliation":[{"name":"Unit of Otorhinolaryngology, Department of Neuroscience, Reproductive Sciences and Dentistry, Federico II University of Naples, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4312-4711","authenticated-orcid":false,"given":"Salvatore","family":"Allosso","sequence":"additional","affiliation":[{"name":"Unit of Otorhinolaryngology, Department of Neuroscience, Reproductive Sciences and Dentistry, Federico II University of Naples, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"D\u2019aniello","sequence":"additional","affiliation":[{"name":"Unit of Otorhinolaryngology, Department of Neuroscience, Reproductive Sciences and Dentistry, Federico II University of Naples, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuela","family":"Pappalardo","sequence":"additional","affiliation":[{"name":"Unit of Otorhinolaryngology, Department of Neuroscience, Reproductive Sciences and Dentistry, Federico II University of Naples, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Catalano","sequence":"additional","affiliation":[{"name":"Unit of Otorhinolaryngology, Department of Neuroscience, Reproductive Sciences and Dentistry, Federico II University of Naples, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Quaremba","sequence":"additional","affiliation":[{"name":"Department of Advanced Biomedical Sciences, Federico II University of Naples, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaetano","family":"Motta","sequence":"additional","affiliation":[{"name":"Unit of Otorhinolaryngology, University Luigi Vanvitelli, 80138 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grazia","family":"Salerno","sequence":"additional","affiliation":[{"name":"Unit of Otorhinolaryngology, Department of Neuroscience, Reproductive Sciences and Dentistry, Federico II University of Naples, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1111\/1460-6984.12148","article-title":"Quality of life after total laryngectomy: Functioning, psychological well-being and self-efficacy","volume":"50","author":"Perry","year":"2015","journal-title":"Int. J. Lang. Commun. Disord."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1017\/S0022215119000215","article-title":"Quality of life after total laryngectomy: Evaluating the effect of socioeconomic status","volume":"133","author":"Scott","year":"2019","journal-title":"J. Laryngol. Otol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"324","DOI":"10.3109\/17549507.2013.785591","article-title":"Living with the altered self: A qualitative study of life after total laryngectomy","volume":"15","author":"Rickford","year":"2013","journal-title":"Int. J. Speech Lang. Pathol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.otorri.2017.02.006","article-title":"Impact of total laryngectomy on return to work","volume":"69","author":"Costa","year":"2018","journal-title":"Acta Otorrinolaringol. Esp."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.otc.2015.04.013","article-title":"Voice Restoration After Total Laryngectomy","volume":"48","author":"Tang","year":"2015","journal-title":"Otolaryngol. Clin. N. Am."},{"key":"ref_6","unstructured":"Ward, E.C., and van As-Brooks, C.J. (2014). Head and Neck Cancer: Treatment, Rehabilitation, and Outcomes, Plural Publishing."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"81","DOI":"10.3389\/fmed.2017.00081","article-title":"Rehabilitation after Total Laryngectomy\u2014A Tribute to the Pioneers of Voice Restoration in the Last Two Centuries","volume":"4","author":"Lorenz","year":"2017","journal-title":"Front. Med."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"133","DOI":"10.2147\/MDER.S133225","article-title":"The electrolarynx: Voice restoration after total laryngectomy","volume":"10","author":"Kaye","year":"2017","journal-title":"Med. Devices"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1007\/s00405-016-4310-0","article-title":"Social support and substitute voice acquisition on psychological adjustment among patients after laryngectomy","volume":"274","author":"Kotake","year":"2017","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s00405-005-0960-z","article-title":"Perceptual evaluation of substitution voices: Development and evaluation of the (I)INFVo rating scale","volume":"263","author":"Moerman","year":"2005","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1007\/s00405-005-1033-z","article-title":"The INFVo perceptual rating scale for substitution voicing: Development and reliability","volume":"263","author":"Moerman","year":"2006","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1002\/hed.23198","article-title":"Reliability and validity of the Italian self-evaluation of communication experiences after laryngeal cancer questionnaire","volume":"35","author":"Schindler","year":"2013","journal-title":"Head Neck"},{"key":"ref_13","first-page":"121","article-title":"Reliability of the Italian INFVo scale and correlations with objective measures and VHI scores","volume":"33","author":"Schindler","year":"2013","journal-title":"Acta Otorhinolaryngol. Ital."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"3537","DOI":"10.1007\/s00520-019-4647-1","article-title":"Integrated rehabilitation after total laryngectomy: A pilot trial study","volume":"27","author":"Longobardi","year":"2019","journal-title":"Support. Care Cancer"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1111\/coa.13924","article-title":"Long-term voice outcomes and quality of life after open partial horizontal laryngectomy type II vs. total laryngectomy: A cross-sectional study","volume":"47","author":"Longobardi","year":"2022","journal-title":"Clin. Otolaryngol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"2248","DOI":"10.1002\/hed.27132","article-title":"Voice and communication after open partial horizontal laryngectomies: A cross-sectional outcome study","volume":"44","author":"Fantini","year":"2022","journal-title":"Head Neck"},{"key":"ref_17","unstructured":"Hirano, M. (1981). Clinical Examination of Voice, Springer."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1007\/s00405-007-0318-9","article-title":"Long-term vocal functional result after glottectomy: A multidimensional analysis","volume":"264","author":"Schindler","year":"2007","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1111\/j.1365-2273.2006.01290.x","article-title":"Multidimensional assessment of female tracheoesophageal prosthetic speech","volume":"31","author":"Kazi","year":"2006","journal-title":"Clin. Otolaryngol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1002\/lary.20125","article-title":"Voice handicap evaluation after supracricoid partial laryngectomy","volume":"119","author":"Makeieff","year":"2009","journal-title":"Laryngoscope"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1097\/00005537-200207000-00027","article-title":"Functional analysis after supracricoid partial laryngectomy with cricohyoidoepiglottopexy","volume":"112","author":"Bron","year":"2002","journal-title":"Laryngoscope"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1080\/00016480500469024","article-title":"Supracricoid laryngectomies: Long-term oncological and functional results","volume":"126","author":"Laudadio","year":"2006","journal-title":"Acta Otolaryngol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/S0892-1997(99)80010-1","article-title":"Validation of an instrument to measure voice-related quality of life (V-RQOL)","volume":"13","author":"Hogikyan","year":"1999","journal-title":"J. Voice"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1044\/1058-0360.0203.82","article-title":"Development and assessment of a scale addressing communication needs of patients with laryngectomies","volume":"2","author":"Blood","year":"1993","journal-title":"Am. J. Speech-Lang. Pathol."},{"key":"ref_25","first-page":"96","article-title":"V-RQOL as a tool for assessing the impact of voice disorders on the quality of life in occupational voice users","volume":"14","author":"Morawska","year":"2015","journal-title":"Otorynolaryngologia"},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Rangarajan, A., Selvaraj, J.L., and Santhanam, D.P. (2019). The Voice-Related Quality Of Life: A Study on the Reliability and Validity of the Tamil Version. Clin. Med. Insights Ear Nose Throat, 12.","DOI":"10.1177\/1179550619831049"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1002\/hed.21409","article-title":"Voice-related quality of life (V-RQOL) outcomes in laryngectomees","volume":"33","author":"Moukarbel","year":"2011","journal-title":"Head Neck"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1007\/s00106-009-1953-9","article-title":"Graduierung des Voice-Related-Quality-of-Life-Index [Grading of the voice-related quality of life index]","volume":"57","author":"Hoppe","year":"2009","journal-title":"HNO"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1080\/028418699431159","article-title":"A cross-sectional validation study of Self-Evaluation of Communication Experiences after Laryngeal Cancer\u2014A questionnaire for use in the voice rehabilitation of laryngeal cancer patients","volume":"38","author":"Finizia","year":"1999","journal-title":"Acta Oncol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1177\/0194599812437315","article-title":"Coping and Quality of Life After Total Laryngectomy","volume":"146","author":"Eadie","year":"2012","journal-title":"Otolaryngol. Head Neck Surg."},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Johansson, M., Ryd\u00e9n, A., and Finizia, C. (2008). Self-evaluation of communication experiences after laryngeal cancer\u2014A longitudinal questionnaire study in patients with laryngeal cancer. BMC Cancer, 8.","DOI":"10.1186\/1471-2407-8-80"},{"key":"ref_32","unstructured":"Boersma, P., and Weenink, D. (2022, October 20). PRAAT: Doing Phonetics by Computer, Version 5.2.34. Available online: http:\/\/www.fon.hum.uva.nl\/praat\/."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1007\/s00405-003-0681-0","article-title":"Objective evaluation of the quality of substitution voices","volume":"261","author":"Moerman","year":"2004","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"3511","DOI":"10.1121\/1.402840","article-title":"Pitch and voiced\/unvoiced determination with an auditory model","volume":"91","author":"Martens","year":"1992","journal-title":"J. Acoust. Soc. Am."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"340","DOI":"10.3102\/00346543052003340","article-title":"Analyzing and Interpreting Significant MANOVAs","volume":"52","author":"Bray","year":"1982","journal-title":"Rev. Educ. Res."},{"key":"ref_36","first-page":"245","article-title":"Tracheoesophageal prostheses","volume":"12","author":"Motta","year":"1992","journal-title":"Acta Otorhinolaryngol. Ital."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.jvoice.2014.09.002","article-title":"Quality of life in patients submitted to total laryngectomy","volume":"29","author":"Feliciano","year":"2015","journal-title":"J. Voice"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1111\/1460-6984.12511","article-title":"Women\u2019s perspective on life after total laryngectomy: A qualitative study","volume":"55","author":"Kornman","year":"2020","journal-title":"Int. J. Lang. Commun. Disord."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1186\/s12955-020-1281-z","article-title":"Quality of life after total laryngectomy: Impact of different vocal rehabilitation methods in a middle income country","volume":"18","author":"Souza","year":"2020","journal-title":"Health Qual. Life Outcomes"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"3431","DOI":"10.1007\/s00405-014-3335-5","article-title":"The effects of indwelling voice prosthesis on the quality of life, depressive symptoms, and self-esteem in patients with total laryngectomy","volume":"272","author":"Polat","year":"2015","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"127","DOI":"10.4103\/1735-1995.196609","article-title":"The impact of vocal rehabilitation on quality of life and voice handicap in patients with total laryngectomy","volume":"21","author":"Drugan","year":"2016","journal-title":"J. Res. Med. Sci."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"675","DOI":"10.2147\/PRBM.S212793","article-title":"Verbal performance of total laryngectomized patients rehabilitated with esophageal speech and tracheoesophageal speech: Impacts on patient quality of life","volume":"12","author":"Allegra","year":"2019","journal-title":"Psychol. Res. Behav. Manag."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"162","DOI":"10.14639\/0392-100X-2227","article-title":"Voice prosthesis rehabilitation after total laryngectomy: Are satisfaction and quality of life maintained over time?","volume":"39","author":"Galli","year":"2019","journal-title":"Acta Otorhinolaryngol. Ital."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/978-3-319-65421-8_3","article-title":"Role of the Speech-Language Pathologist (SLP) in the Head and Neck Cancer Team","volume":"174","author":"Hansen","year":"2018","journal-title":"Cancer Treat Res."},{"key":"ref_45","first-page":"633","article-title":"Oncological and psychological evaluation of laryngectomized patients, pre and post implantation of voice prostheses. A single center experience","volume":"93","author":"Sivero","year":"2022","journal-title":"Ann. Ital. Chir."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"95791","DOI":"10.18632\/oncotarget.21327","article-title":"Aggressiveness pattern and second primary tumor risk associated with basaloid squamous cell carcinoma of the larynx","volume":"8","author":"Ricciardiello","year":"2017","journal-title":"Oncotarget"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"2595","DOI":"10.3892\/ol.2016.4265","article-title":"Role of perineural invasion as a prognostic factor in laryngeal cancer","volume":"11","author":"Mesolella","year":"2016","journal-title":"Oncol. Lett."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s00405-017-4790-6","article-title":"Objective and subjective voice outcomes after total laryngectomy: A systematic review","volume":"275","author":"Hilgers","year":"2018","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"ref_49","first-page":"e075","article-title":"Supracricoid Partial Laryngectomy: Oncological and Functional Outcomes","volume":"26","author":"Mesolella","year":"2021","journal-title":"Int. Arch. Otorhinolaryngol."},{"key":"ref_50","first-page":"145","article-title":"New Therapeutic Strategies in the Treatment of Stomal Recurrence after Total Laryngectomy: Role of Immunotherapy","volume":"21","author":"Mesolella","year":"2022","journal-title":"Ear Nose Throat J."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1177\/0194599812461755","article-title":"Auditory-perceptual speech outcomes and quality of life after total laryngectomy","volume":"148","author":"Eadie","year":"2013","journal-title":"Otolaryngol. Head Neck Surg."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1177\/0194599814524704","article-title":"The Influence of Electrolarynx Use on Postlaryngectomy Voice-Related Quality of Life","volume":"150","author":"Cox","year":"2014","journal-title":"Otolaryngol. Head Neck Surg."}],"container-title":["Journal of Personalized Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4426\/13\/3\/570\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:00:51Z","timestamp":1760122851000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4426\/13\/3\/570"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,22]]},"references-count":52,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2023,3]]}},"alternative-id":["jpm13030570"],"URL":"https:\/\/doi.org\/10.3390\/jpm13030570","relation":{},"ISSN":["2075-4426"],"issn-type":[{"value":"2075-4426","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,22]]}}}