{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:02:03Z","timestamp":1791813723984,"version":"4.3.4"},"reference-count":25,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T00:00:00Z","timestamp":1681084800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>The hemolysis rate in the emergency department (ED) is higher compared to that in other departments. We propose a new blood sampling technique without repeated venipuncture to reduce hemolysis and compare the hemolysis rate between blood collected by this method and that collected with an intravenous (IV) catheter. This prospective study included a nonconsecutive sample of patients visiting the ED (aged \u2265 18 years) of a tertiary urban university hospital. The intravenous catheterization was performed by three pre-trained nurses. The new blood collection technique involved sample collection without removing the catheter needle, performed immediately before the conventional method (through an IV catheter), without additional venipuncture. Two blood samples were collected from each patient using both the new and conventional methods, and the hemolysis index was evaluated. We compared the hemolysis rate between the two methods. From the 260 patients enrolled in this study, 147 (56.5%) were male, and the mean age was 58.3 years. The hemolysis rate of the new blood collection method was 1.9% (5\/260), which was significantly lower than that of the conventional method (7.3%; 19\/260) (p = 0.001). The new blood collection method can reduce the hemolysis rate as compared to the conventional blood collection method.<\/jats:p>","DOI":"10.3390\/jpm13040651","type":"journal-article","created":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T07:11:43Z","timestamp":1681110703000},"page":"651","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Hemolysis Control in the Emergency Department by Interventional Blood Sampling"],"prefix":"10.3390","volume":"13","author":[{"given":"Hyeseung","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, Guri Hospital, Hanyang University College of Medicine, Guri 11923, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5700-3331","authenticated-orcid":false,"given":"Heekyung","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Guri Hospital, Hanyang University College of Medicine, Guri 11923, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8475-3453","authenticated-orcid":false,"given":"Changsun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Guri Hospital, Hanyang University College of Medicine, Guri 11923, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3203-1672","authenticated-orcid":false,"given":"Hyungoo","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Guri Hospital, Hanyang University College of Medicine, Guri 11923, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inhye","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Yongin Severance Hospital, Yongin 16995, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yihyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Philosophy, University of Nevada, Las Vegas, NV 89154, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,10]]},"reference":[{"key":"ref_1","unstructured":"CLSI (2007). 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Anal."}],"container-title":["Journal of Personalized Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4426\/13\/4\/651\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:13:17Z","timestamp":1760123597000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4426\/13\/4\/651"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,10]]},"references-count":25,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,4]]}},"alternative-id":["jpm13040651"],"URL":"https:\/\/doi.org\/10.3390\/jpm13040651","relation":{},"ISSN":["2075-4426"],"issn-type":[{"value":"2075-4426","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,10]]}}}