{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T06:44:30Z","timestamp":1773384270908,"version":"3.50.1"},"reference-count":34,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2023,5,24]],"date-time":"2023-05-24T00:00:00Z","timestamp":1684886400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>The spleen is the most commonly injured organ in blunt abdominal trauma. Its management depends on hemodynamic stability. According to the American Association for the Surgery of Trauma-Organ Injury Scale (AAST-OIS \u2265 3), stable patients with high-grade splenic injuries may benefit from preventive proximal splenic artery embolization (PPSAE). This ancillary study, using the SPLASH multicenter randomized prospective cohort, evaluated the feasibility, safety, and efficacy of PPSAE in patients with high-grade blunt splenic trauma without vascular anomaly on the initial CT scan. All patients included were over 18 years old, had high-grade splenic trauma (\u2265AAST-OIS 3 + hemoperitoneum) without vascular anomaly on the initial CT scan, received PPSAE, and had a CT scan at one month. Technical aspects, efficacy, and one-month splenic salvage were studied. Fifty-seven patients were reviewed. Technical efficacy was 94% with only four proximal embolization failures due to distal coil migration. Six patients (10.5%) underwent combined embolization (distal + proximal) due to active bleeding or focal arterial anomaly discovered during embolization. The mean procedure time was 56.5 min (SD = 38.1 min). Embolization was performed with an Amplatzer\u2122 vascular plug in 28 patients (49.1%), a Penumbra occlusion device in 18 patients (31.6%), and microcoils in 11 patients (19.3%). There were two hematomas (3.5%) at the puncture site without clinical consequences. There were no rescue splenectomies. Two patients were re-embolized, one on Day 6 for an active leak and one on Day 30 for a secondary aneurysm. Primary clinical efficacy was, therefore, 96%. There were no splenic abscesses or pancreatic necroses. The splenic salvage rate on Day 30 was 94%, while only three patients (5.2%) had less than 50% vascularized splenic parenchyma. PPSAE is a rapid, efficient, and safe procedure that can prevent splenectomy in high-grade spleen trauma (AAST-OIS) \u2265 3 with high splenic salvage rates.<\/jats:p>","DOI":"10.3390\/jpm13060889","type":"journal-article","created":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T02:58:48Z","timestamp":1684983528000},"page":"889","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Preventive Proximal Splenic Artery Embolization for High-Grade AAST-OIS Adult Spleen Trauma without Vascular Anomaly on the Initial CT Scan: Technical Aspect, Safety, and Efficacy\u2014An Ancillary Study"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7612-5924","authenticated-orcid":false,"given":"Skander","family":"Sammoud","sequence":"first","affiliation":[{"name":"Department of Radiology, N\u00eemes Car\u00e9meau University Hospital, 30900 Nimes, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9039-6488","authenticated-orcid":false,"given":"Julien","family":"Ghelfi","sequence":"additional","affiliation":[{"name":"Institute for Advanced Biosciences, Inserm U 1209, CNRS UMR 5309, Universit\u00e9 Grenoble Alpes, 38000 Grenoble, France"},{"name":"Department of Radiology, Grenoble-Alpes University Hospital, 38000 Grenoble, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandrine","family":"Barbois","sequence":"additional","affiliation":[{"name":"Department of Digestive Surgery, University Hospital Grenoble Alpes, 38043 Grenoble, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Paul","family":"Beregi","sequence":"additional","affiliation":[{"name":"Department of Radiology, N\u00eemes Car\u00e9meau University Hospital, 30900 Nimes, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Arvieux","sequence":"additional","affiliation":[{"name":"Department of Digestive and Emergency Surgery, Grenoble Alpes University Hospital, 38043 Grenoble, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7816-8178","authenticated-orcid":false,"given":"Julien","family":"Frandon","sequence":"additional","affiliation":[{"name":"Department of Radiology, N\u00eemes Car\u00e9meau University Hospital, 30900 Nimes, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,24]]},"reference":[{"key":"ref_1","first-page":"898","article-title":"Nonoperative management of adult blunt splenic injury with and without splenic artery embolotherapy: A meta-analysis","volume":"71","author":"Requarth","year":"2011","journal-title":"J. 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