{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:15:01Z","timestamp":1791245701138,"version":"4.1.0"},"reference-count":30,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T00:00:00Z","timestamp":1685404800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>Introduction: Patients with Inflammatory Bowel Disease (IBD), including Crohn\u2019s disease (CD) and ulcerative colitis (UC), are at high risk of developing malignancies, so prevention and adherence to cancer screening may improve detection. The aim of this study was to assess compliance with medical recommendations, especially primary and secondary prevention of cancer. Methods: This one-center cross-sectional study was carried out between June and December 2021 amongst patients at the Department of Internal Medicine and Gastroenterology, IBD Division, National Medical Institute of Ministry of Interior Affairs and Administrations, or the outpatient clinic. Patients with IBD were asked to complete an anonymous questionnaire, which included 42 questions concerning lifestyle, cancer risk factors, cancer history, and checkups. Statistical methods: The results of the qualitative variables were expressed as frequencies and percentages. We used Fisher\u2019s exact test and the Chi-squared test. A value of p &lt; 0.05 was considered significant. Statistical analyses were performed with the SPSS statistical package. Results: A total of 313 patients were enrolled in the study: 145 women and 168 men. In the group, 182 had Crohn\u2019s disease (CD), 120 had ulcerative colitis (UC), and 11 with IBDU (unclassified IBD). Most participants had a disease duration of over 8 years and received biological treatment, corticoids, and\/or immunosuppressive therapy. Amongst respondents, 17% (31) of patients with CD and 25.8% (31) with UC were overweight, and 10.5% (19) with CD and 15.8% (19) with UC were obese (p = 0.017). We found that 16.3% of all respondents were smokers (79.6% (144) with CD, 90.8% (109) with UC, and 72.7% (8) with IBDU; p = 0.053), and 33.9% declared that they consumed alcohol (39.4% (71) with CD, 26.9% (32) with UC, and 18.2% (2) with IBDU; p = 0.045). A total of 25.4% of patients were exposed to UV radiation, but only 18.8% used sunblock. In addition, 58.8% (67) of patients with CD and 35.8% (19) with UC receiving immunosuppressants had regular laboratory tests (p = 0.02). Furthermore, 41.4% (46) of patients with UC, 27.1% (49) of patients with CD, and 70.0% (7) of patients with IBDU declared not to perform any dermatological control (p = 0.013). A total of 77% of patients had abdominal ultrasound. Out of 52.9% of patients for whom colonoscopy was recommended, only 27.3% had it performed (16.9% (30) with CD vs. 43.1% (50) with UC p &lt; 0.001). Most examinations were ordered by gastroenterologists. Female patients had regular breast control (CD, 78.6% (66); UC, 91.2% (52); IBDU, 50% (2); p = 0.034), and 93.8% (76) had gynecological examinations. Additionally, 80.2% of patients knew about HPV, but most declared not to be vaccinated. A total of 17.9% of patients had urological control, but most had no important pathology detected. Conclusions: According to our study, many patients are still exposed to risk factors, such as obesity, smoking, and low physical activity, that are modifiable. Laboratory tests in patients with immunosuppressive treatment should be performed regularly. Systematic control, especially dermatological checkups, should be recommended. Additionally, not only gastrologists but also other specialists and GPs should remind patients about regular checkups. Primary prevention, such as HPV vaccinations, should be recommended to all patients.<\/jats:p>","DOI":"10.3390\/jpm13060913","type":"journal-article","created":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T03:02:23Z","timestamp":1685415743000},"page":"913","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Awareness and Compliance with the Recommendations of Primary and Secondary Prevention of Cancer in Patients with Inflammatory Bowel Disease"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9301-9995","authenticated-orcid":false,"given":"Edyta","family":"Tulewicz-Marti","sequence":"first","affiliation":[{"name":"Department of Internal Medicine and Gastroenterology with Inflammatory Bowel Disease Unit, National Medical Institute of the Ministry of Interior Affairs and Administration-Warsaw, 02-507 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beata","family":"St\u0119pie\u0144-Wrochna","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Gastroenterology with Inflammatory Bowel Disease Unit, National Medical Institute of the Ministry of Interior Affairs and Administration-Warsaw, 02-507 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarzyna","family":"Maciejewska","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Gastroenterology with Inflammatory Bowel Disease Unit, National Medical Institute of the Ministry of Interior Affairs and Administration-Warsaw, 02-507 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micha\u0142","family":"\u0141odyga","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Grochowski Hospital, 04-073 Warsaw, Poland"},{"name":"Department of Internal Medicine, Faculty of Health Science, Medical University of Warsaw, 02-091 Warszawa, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1310-3274","authenticated-orcid":false,"given":"Katarzyna","family":"Kar\u0142owicz","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Gastroenterology with Inflammatory Bowel Disease Unit, National Medical Institute of the Ministry of Interior Affairs and Administration-Warsaw, 02-507 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3866-4905","authenticated-orcid":false,"given":"Konrad","family":"Lewandowski","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Gastroenterology with Inflammatory Bowel Disease Unit, National Medical Institute of the Ministry of Interior Affairs and Administration-Warsaw, 02-507 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grazyna","family":"Rydzewska","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Gastroenterology with Inflammatory Bowel Disease Unit, National Medical Institute of the Ministry of Interior Affairs and Administration-Warsaw, 02-507 Warsaw, Poland"},{"name":"Collegium Medicum, Jana Kochanowski University, 25-317 Kielce, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1002\/jso.2930180302","article-title":"The primary and secondary prevention of cancer","volume":"18","author":"Spratt","year":"1981","journal-title":"J. Surg. Oncol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2769","DOI":"10.1016\/S0140-6736(17)32448-0","article-title":"Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: A systematic review of population-based studies","volume":"390","author":"Ng","year":"2017","journal-title":"Lancet"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.3748\/wjg.v19.i10.1505","article-title":"Epidemiology and inflammatory bowel diseases","volume":"19","year":"2013","journal-title":"World J. Gastroenterol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1200\/EDBK_200093","article-title":"Lifestyle Modifications and Policy Implications for Primary and Secondary Cancer Prevention: Diet, Exercise, Sun Safety, and Alcohol Reduction","volume":"38","author":"LoConte","year":"2018","journal-title":"Am. Soc. Clin. Oncol. Educ. Book."},{"key":"ref_5","first-page":"119","article-title":"Choroba nowotworowa u pacjenta z nieswoist\u0105 chorob\u0105 zapaln\u0105 jelit\u2014Zasady post\u0119powania","volume":"8","author":"Eder","year":"2016","journal-title":"Gastroenterol. Klin."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"309","DOI":"10.5114\/pg.2020.101559","article-title":"The risk of small bowel adenocarcinoma in patients with Crohn\u2019s disease","volume":"15","author":"Lech","year":"2020","journal-title":"Gastroenterol. Rev. Przegl\u0105d Gastroenterol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5114\/pg.2023.125882","article-title":"Guidelines for the management of ulcerative colitis. Recommendations of the Polish Society of Gastroenterology and the Polish National Consultant in Gastroenterology","volume":"18","author":"Eder","year":"2023","journal-title":"Gastroenterol. Rev. Przegl\u0105d Gastroenterol."},{"key":"ref_8","first-page":"257","article-title":"Guidelines for the management of patients with Crohn\u2019s disease. Recommendations of the Polish Society of Gastroenterology and the Polish National Consultant in Gastroenterology","volume":"16","author":"Eder","year":"2021","journal-title":"Prz. Gastroenterol."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Gordon, H., Biancone, L., Fiorino, G., Katsanos, K.H., Kopylov, U., Sulais, E.A., Axelrad, J.E., Balendran, K., Burisch, J., and de Ridder, L. (2022). ECCO Guidelines on Inflammatory Bowel Disease and Malignancies. J. Crohn's Colitis., jjac187.","DOI":"10.1093\/ecco-jcc\/jjac187"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1093\/ecco-jcc\/jjv141","article-title":"European Evidence-based Consensus: Inflammatory Bowel Disease and Malignancies","volume":"9","author":"Annese","year":"2015","journal-title":"J. Crohn's Colitis"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1038\/nrgastro.2016.181","article-title":"Obesity in IBD: Epidemiology, pathogenesis, disease course and treatment outcomes","volume":"14","author":"Singh","year":"2017","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Islam, M.R., Arthur, S., Haynes, J., Butts, M.R., Nepal, N., and Sundaram, U. (2022). The Role of Gut Microbiota and Metabolites in Obesity-Associated Chronic Gastrointestinal Disorders. Nutrients, 14.","DOI":"10.3390\/nu14030624"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"832","DOI":"10.14309\/ajg.0000000000000608","article-title":"Effect of Lifestyle Factors on Outcomes in Patients With Inflammatory Bowel Diseases","volume":"115","author":"Rozich","year":"2020","journal-title":"Am. J. Gastroenterol."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Kadenczki, O., Dezsofi, A., Cseh, A., Szucs, D., Vass, N., Nemes, E., Tarnok, A., Szakos, E., Guthy, I., and Kovacs, M. (2022). Disease Activity Is Associated with Obesity in Newly Diagnosed Pediatric Patients with Ulcerative Colitis. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph192316091"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1634\/theoncologist.2009-0285","article-title":"Obesity and cancer","volume":"15","author":"Wolin","year":"2010","journal-title":"Oncologist"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1111\/apt.12440","article-title":"Smoking does influence disease behaviour and impacts the need for therapy in Crohn's disease in the biologic era","volume":"38","author":"Nunes","year":"2013","journal-title":"Aliment. Pharmacol. Ther."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1093\/ecco-jcc\/jjab036","article-title":"Increased Risk of High-grade Cervical Neoplasia in Women with Inflammatory Bowel Disease: A Case-controlled Cohort Study","volume":"15","author":"Goetgebuer","year":"2021","journal-title":"J. Crohn\u2019s Colitis"},{"key":"ref_18","first-page":"211","article-title":"Alcohol Use in Patients With Inflammatory Bowel Disease","volume":"17","author":"Kane","year":"2021","journal-title":"Gastroenterol. Hepatol."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Rumgay, H., Murphy, N., Ferrari, P., and Soerjomataram, I. (2021). Alcohol and Cancer: Epidemiology and Biological Mechanisms. Nutrients, 13.","DOI":"10.3390\/nu13093173"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1136\/gutjnl-2013-305763","article-title":"Risk of new or recurrent cancer under immunosuppressive therapy in patients with IBD and previous cancer","volume":"63","author":"Beaugerie","year":"2014","journal-title":"Gut"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1038\/s41395-018-0360-9","article-title":"Malignancies in Inflammatory Bowel Disease: Frequency, Incidence and Risk Factors-Results from the Swiss IBD Cohort Study","volume":"114","author":"Scharl","year":"2019","journal-title":"Am. J. Gastroenterol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000447259","article-title":"Malignancies in Patients with Inflammatory Bowel Disease: A Single-Centre Experience","volume":"94","author":"Madanchi","year":"2016","journal-title":"Digestion"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1038\/ajg.2016.304","article-title":"Cancer in Elderly Onset Inflammatory Bowel Disease: A Population-Based Study","volume":"111","author":"Cheddani","year":"2016","journal-title":"Am. J. Gastroenterol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1016\/j.cgh.2016.04.039","article-title":"Biologic Therapies and Risk of Infection and Malignancy in Patients With Inflammatory Bowel Disease: A Systematic Review and Network Meta-analysis","volume":"14","author":"Bonovas","year":"2016","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1111\/apt.16832","article-title":"Adherence to endoscopic surveillance for advanced lesions and colorectal cancer in inflammatory bowel disease: An AEG and GETECCU collaborative cohort study","volume":"55","author":"Ballester","year":"2022","journal-title":"Aliment. Pharmacol. Ther."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1097\/MIB.0b013e3182802a3c","article-title":"Factors that affect adherence to surveillance colonoscopy in patients with inflammatory bowel disease","volume":"19","author":"Friedman","year":"2013","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1080\/00365521.2017.1278785","article-title":"Clinicians' adherence to international guidelines in the clinical care of adults with inflammatory bowel disease","volume":"52","author":"Jackson","year":"2017","journal-title":"Scand J. Gastroenterol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1093\/ibd\/izx062","article-title":"Neoplasia and Precursor Lesions of the Female Genital Tract in IBD: Epidemiology, Role of Immunosuppressants, and Clinical Implications","volume":"24","author":"Hazenberg","year":"2018","journal-title":"Inflamm. Bowel Dis."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1016\/j.cgh.2020.02.009","article-title":"Predicting, Preventing, and Managing Treatment-Related Complications in Patients With Inflammatory Bowel Diseases","volume":"18","author":"Beaugerie","year":"2020","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1080\/2090598X.2020.1761674","article-title":"Inflammatory bowel disease and prostate cancer risk: A systematic review","volume":"18","author":"Haddad","year":"2020","journal-title":"Arab. J. Urol."}],"container-title":["Journal of Personalized Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4426\/13\/6\/913\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:44:55Z","timestamp":1760125495000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4426\/13\/6\/913"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,30]]},"references-count":30,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2023,6]]}},"alternative-id":["jpm13060913"],"URL":"https:\/\/doi.org\/10.3390\/jpm13060913","relation":{},"ISSN":["2075-4426"],"issn-type":[{"value":"2075-4426","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,30]]}}}