{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:42:18Z","timestamp":1790613738583,"version":"4.1.0"},"reference-count":28,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T00:00:00Z","timestamp":1689292800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>Background: Foot drop (FD) is characterized by an inability to lift the foot against gravity because of dorsiflexor muscle weakness. The aim of the present study is to report a clinical case of acute non-traumatic FD in patients with peroneal intraneural ganglion, after performing a scoping review on the methodological management of this disease. Methods: We performed a review of the literature and reported the case of a 49-year-old man with acute FD caused by an intraneural ganglion cyst of the peroneal nerve. Results: Out of a total of 201 articles, 3 were suitable for our review beyond our case report. The acute FD caused by peroneal intraneural ganglion can be managed by a careful clinical\u2013instrumental differential diagnosis. A targeted surgery with subsequent rehabilitation produced a satisfactory motor recovery. Conclusions: Acute FD requires an appropriate diagnostic\u2013therapeutic framework to identify and effectively treat the causes in order to promote complete recovery<\/jats:p>","DOI":"10.3390\/jpm13071137","type":"journal-article","created":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T00:28:06Z","timestamp":1689294486000},"page":"1137","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Acute Foot Drop Caused by Intraneural Ganglion Cyst of the Peroneal Nerve: Literature Review and Case Report"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-7375-9792","authenticated-orcid":false,"given":"Giuseppe","family":"della Vecchia","sequence":"first","affiliation":[{"name":"Department of Women, Child, General and Specialistic Surgery, University of Campania \u201cLuigi Vanvitelli\u201d, 80138 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8693-3842","authenticated-orcid":false,"given":"Alfonso","family":"Baldi","sequence":"additional","affiliation":[{"name":"Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania \u201cL. Vanvitelli\u201d, 81100 Caserta, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9659-0847","authenticated-orcid":false,"given":"Maria Beatrice","family":"Passavanti","sequence":"additional","affiliation":[{"name":"Department of Women, Child, General and Specialistic Surgery, University of Campania \u201cLuigi Vanvitelli\u201d, 80138 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6435-7680","authenticated-orcid":false,"given":"Angela","family":"Lucariello","sequence":"additional","affiliation":[{"name":"Department of Sport Sciences and Wellness, University of Naples \u201cParthenope\u201d, 80100 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3905-6154","authenticated-orcid":false,"given":"Antonio","family":"De Luca","sequence":"additional","affiliation":[{"name":"Department of Mental and Physical Health and Preventive Medicine, Section of Human Anatomy, University of Campania \u201cLuigi Vanvitelli\u201d, 80131 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1317-7994","authenticated-orcid":false,"given":"Paolo","family":"De Blasiis","sequence":"additional","affiliation":[{"name":"Department of Mental and Physical Health and Preventive Medicine, Section of Human Anatomy, University of Campania \u201cLuigi Vanvitelli\u201d, 80131 Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,7,14]]},"reference":[{"key":"ref_1","first-page":"347","article-title":"The Interdisciplinary Management of Foot Drop","volume":"116","author":"Carolus","year":"2019","journal-title":"Dtsch. Arztebl. Int."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"411","DOI":"10.7547\/87507315-90-8-411","article-title":"A case of peroneal neuropathy-induced footdrop. Correlated and compensatory lower-extremity function","volume":"90","author":"Vlahovic","year":"2000","journal-title":"J. Am. Podiatr. Med. Assoc."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1136\/jnnp.2008.149393","article-title":"Foot drop: Where, why and what to do?","volume":"8","author":"Stewart","year":"2008","journal-title":"Pract Neurol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1080\/17434440.2021.1857729","article-title":"Trends and Technologies in Rehabilitation of Foot Drop: A Systematic Review","volume":"18","author":"Alnajjar","year":"2021","journal-title":"Expert. Rev. Med. Devices"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"S77","DOI":"10.1016\/j.injury.2019.10.054","article-title":"Benign peripheral nerve tumors","volume":"50","author":"Kokkalis","year":"2019","journal-title":"Injury"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1007\/s00590-021-02903-7","article-title":"Intraneural ganglion cysts of the peroneal nerve","volume":"31","author":"Kokkalis","year":"2021","journal-title":"Eur. J. Orthop. Surg. Traumatol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"2479","DOI":"10.1007\/s00701-018-3715-5","article-title":"Superfcial radial intraneural ganglion cysts at the wrist","volume":"160","author":"Spinner","year":"2018","journal-title":"Acta Neurochir."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1097\/JSA.0b013e3182191897","article-title":"Drop foot after knee dislocation: Evaluation and treatment","volume":"19","author":"Cush","year":"2011","journal-title":"Sports Med. Arthrosc. Rev."},{"key":"ref_9","first-page":"374","article-title":"Peroneal nerve injury with foot drop complicating ankle sprain\u2014A series of four cases with review of the literature","volume":"67","author":"Brief","year":"2009","journal-title":"Bull. NYU Hosp. Jt. Dis."},{"key":"ref_10","first-page":"1904595","article-title":"Acute Complete Foot Drop Caused by Intraneural Ganglion Cyst without a Prior Traumatic Event","volume":"2020","author":"Stamiris","year":"2020","journal-title":"Case Rep. Orthop."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: An updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.jclinepi.2017.04.026","article-title":"CARE guidelines for case reports: Explanation and elaboration document","volume":"89","author":"Riley","year":"2017","journal-title":"J. Clin. Epidemiol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1097\/00131402-200412000-00001","article-title":"Acute onset of deep peroneal neuropathy during a golf game resulting from a ganglion cyst","volume":"6","author":"Rubin","year":"2004","journal-title":"J. Clin. Neuromuscul. Dis."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"20","DOI":"10.7547\/20-252","article-title":"Acute-Onset Footdrop Caused by Intraneural Ganglion Cyst of the Common Peroneal Nerve: The Effects of Extraneural Pressure Gradients on Cyst Propagation","volume":"112","author":"Williams","year":"2022","journal-title":"J. Am. Podiatr. Med. Assoc."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.cpm.2020.09.004","article-title":"Evaluation and Treatment of Foot Drop Using Nerve Transfer Techniques","volume":"38","author":"Khan","year":"2021","journal-title":"Clin. Podiatr. Med. Surg."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1080\/08998280.2012.11928809","article-title":"A rare case of intraneural ganglion cyst involving the tibial nerve","volume":"25","author":"Patel","year":"2012","journal-title":"Proc. Bayl. Univ. Med. Cent."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"76","DOI":"10.3171\/jns.1965.23.1.0076","article-title":"Intraneural cyst of the peroneal and ulnar nerves. Report of two cases","volume":"23","author":"Gurdjian","year":"1965","journal-title":"J. Neurosurg."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1227\/00006123-198104000-00018","article-title":"Intraneural ganglion: A case report with electron microscopic observations","volume":"8","author":"Scherman","year":"1981","journal-title":"Neurosurgery"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"330","DOI":"10.3171\/jns.2003.99.2.0330","article-title":"Peroneal intraneural ganglia: The importance of the articular branch. A unifying theory","volume":"99","author":"Spinner","year":"2003","journal-title":"J. Neurosurg."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1007\/s00701-012-1444-8","article-title":"Peripheral neuropathy caused by joint-related cysts: A review of 17 cases","volume":"154","author":"Weyns","year":"2012","journal-title":"Acta Neurochir."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1159\/000368838","article-title":"Peroneal and tibial intraneural ganglion cysts in children","volume":"49","author":"Akcakaya","year":"2013","journal-title":"Pediatr. Neurosurg."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1097\/BPO.0b013e3181558c05","article-title":"Intraneural ganglion cyst of the peroneal nerve in a four-year-old girl: A case report","volume":"27","author":"Johnston","year":"2007","journal-title":"J. Pediatr. Orthop."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"538","DOI":"10.3171\/jns.1992.76.3.0538","article-title":"Ultrasound diagnosis of an intraneural ganglion cyst of the peroneal nerve","volume":"76","author":"Leijten","year":"1992","journal-title":"J. Neurosurg."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"230","DOI":"10.4329\/wjr.v9.i5.230","article-title":"Cystic lesions of peripheral nerves: Are we missing the diagnosis of the intraneural ganglion cyst?","volume":"9","author":"Panwar","year":"2017","journal-title":"World J. Radiol."},{"key":"ref_25","first-page":"157","article-title":"The Cystic Transverse Limb of the Articular Branch: A Pathognomonic Sign for Peroneal Intraneural Ganglia at the Superior Tibiofibular Joint","volume":"59","author":"Spinner","year":"2006","journal-title":"Neurosurgery"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"e11","DOI":"10.1016\/j.wneu.2015.10.023","article-title":"Intraneural Ganglia of the Common Peroneal Nerve in Children: Case Report and Review of the Literature","volume":"86","author":"Consales","year":"2016","journal-title":"World Neurosurg."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.jpedsurg.2009.09.039","article-title":"An unusual cause of paralysis of the peroneal nerve-a case report","volume":"45","author":"Waldschmidt","year":"2010","journal-title":"J. Pediatr. Surg."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"106915","DOI":"10.1016\/j.clineuro.2021.106915","article-title":"Intraneural ganglion cyst of the common peroneal nerve causing foot drop in a 12-year old child","volume":"209","author":"Broekx","year":"2021","journal-title":"Clin. Neurol. 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