{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T02:37:43Z","timestamp":1771641463564,"version":"3.50.1"},"reference-count":47,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T00:00:00Z","timestamp":1698278400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"International Scientific Society of Neuro Psycho Physical Optimization with REAC Technology"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>Post-Polio Syndrome (PPS) is a chronic condition characterized by the emergence of new symptoms and functional decline in individuals who previously had polio. Despite advances in medical understanding, management of PPS remains challenging. This study aimed to evaluate the use of neurobiological modulation treatments using Radio Electric Asymmetric Conveyer (REAC) technology on fatigue and muscle strength. An open-label study was conducted with 17 patients submitted to four neuromodulation protocols: Neuro Postural Optimization (NPO), Neuro Psycho Physical Optimization (NPPO), Neuro Psycho Physical Optimization\u2014Cervico Brachial (NPPO-CB), and Neuromuscular Optimization (NMO). The Time Up and Go (TUG) test, Handgrip Strength Test, and Revised Piper Fatigue Scale (RPFS) were used to assess participants\u2019 fatigue and muscle strength, being applied at the beginning and end of each protocol. The results obtained from the improvement in strength, physical endurance, and particularly the RPFS behavioral dimension, affective dimension, and psychological sensory dimension, through the utilization of REAC neurobiological modulation treatments, highlight this correlation. These results suggest that these treatments could be considered as a potential therapeutic approach for PPS.<\/jats:p>","DOI":"10.3390\/jpm13111536","type":"journal-article","created":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T06:20:16Z","timestamp":1698301216000},"page":"1536","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Improving Strength and Fatigue Resistance in Post-Polio Syndrome Individuals with REAC Neurobiological Treatments"],"prefix":"10.3390","volume":"13","author":[{"given":"Monalisa","family":"Pereira Motta","sequence":"first","affiliation":[{"name":"Division of Neuromuscular Diseases, Department of Neurology and Neurosurgery, Federal University of S\u00e3o Paulo, S\u00e3o Paulo 01000-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Acary Souza Bulle","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Division of Neuromuscular Diseases, Department of Neurology and Neurosurgery, Federal University of S\u00e3o Paulo, S\u00e3o Paulo 01000-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeyce Adrielly","family":"Andr\u00e9 Nogueira","sequence":"additional","affiliation":[{"name":"Division of Neuromuscular Diseases, Department of Neurology and Neurosurgery, Federal University of S\u00e3o Paulo, S\u00e3o Paulo 01000-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alcione Aparecida","family":"Vieira de Souza Moscardi","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Federal University of S\u00e3o Paulo, S\u00e3o Paulo 01000-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudete","family":"Munhoz Teixeira","sequence":"additional","affiliation":[{"name":"Division of Neuromuscular Diseases, Department of Neurology and Neurosurgery, Federal University of S\u00e3o Paulo, S\u00e3o Paulo 01000-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa","family":"Manchim Favaro","sequence":"additional","affiliation":[{"name":"Division of Neuromuscular Diseases, Department of Neurology and Neurosurgery, Federal University of S\u00e3o Paulo, S\u00e3o Paulo 01000-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda Orasmo","family":"Simcsik","sequence":"additional","affiliation":[{"name":"Division of Neuromuscular Diseases, Department of Neurology and Neurosurgery, Federal University of S\u00e3o Paulo, S\u00e3o Paulo 01000-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salete","family":"Conde","sequence":"additional","affiliation":[{"name":"Division of Neuromuscular Diseases, Department of Neurology and Neurosurgery, Federal University of S\u00e3o Paulo, S\u00e3o Paulo 01000-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Clara","family":"Patrizi","sequence":"additional","affiliation":[{"name":"Division of Neuromuscular Diseases, Department of Neurology and Neurosurgery, Federal University of S\u00e3o Paulo, S\u00e3o Paulo 01000-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7675-0313","authenticated-orcid":false,"given":"Chiara","family":"Rinaldi","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Psychology, Drug Area, and Child Health (NEUROFARBA), University of Florence, 50134 Florence, Italy"},{"name":"Department of Adaptive Neuro Psycho Physio Pathology and Neuro Psycho Physical Optimization, Rinaldi Fontani Institute, 50144 Florence, Italy"},{"name":"Department of Regenerative Medicine, Rinaldi Fontani Institute, 50144 Florence, Italy"},{"name":"Research Department, Rinaldi Fontani Foundation, 50144 Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0141-6270","authenticated-orcid":false,"given":"Vania","family":"Fontani","sequence":"additional","affiliation":[{"name":"Department of Adaptive Neuro Psycho Physio Pathology and Neuro Psycho Physical Optimization, Rinaldi Fontani Institute, 50144 Florence, Italy"},{"name":"Department of Regenerative Medicine, Rinaldi Fontani Institute, 50144 Florence, Italy"},{"name":"Research Department, Rinaldi Fontani Foundation, 50144 Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8961-6316","authenticated-orcid":false,"given":"Salvatore","family":"Rinaldi","sequence":"additional","affiliation":[{"name":"Department of Adaptive Neuro Psycho Physio Pathology and Neuro Psycho Physical Optimization, Rinaldi Fontani Institute, 50144 Florence, Italy"},{"name":"Department of Regenerative Medicine, Rinaldi Fontani Institute, 50144 Florence, 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