{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T14:37:59Z","timestamp":1776436679593,"version":"3.51.2"},"reference-count":38,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T00:00:00Z","timestamp":1705968000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>Background: this study aimed to investigate the relationship between acne severity and depression, anxiety, stress, and negative eating attitudes in patients with acne vulgaris. Method: This study was conducted with 81 patients with acne vulgaris who applied to the dermatology outpatient clinic of Karaman Training and Research Hospital. The patients were asked to complete a sociodemographic data form, the three-factor nutrition questionnaire (TFEQ-21), and the depression anxiety stress scale (DASS-21). Acne severity was assessed using the global acne grading system (GAGS) by an expert dermatologist. Results: Of the 81 patients, 74.1% were female and the average age of the cohort was 22.86 years. The average body mass index of the patients was 21.78 and the GAGS average score was 24.25. Correlation tests revealed the lack of any relationship between the GAGS score and the DASS-21 and TFEQ-21 scale scores (and their subscales). The DASS-21 depression subscale was correlated with the TFEQ-21 total score, and TFEQ-21 emotional eating and TFEQ-21 uncontrolled eating scores. Additionally, a relationship was identified between the DASS21-stress subscale score and TFEQ-21 uncontrolled Eating and TFEQ-21 total score, as well as between the DASS21-anxiety scale and the TFEQ-21 total score and TFEQ-21 uncontrolled eating subscale score. Conclusions: Although no relationship was found between acne severity and depression, anxiety, or eating disorders, these conditions can increase the risk of eating disorders among acne patients. Therefore, it is critical to take the necessary precautions for the treatment of depression and anxiety disorders in this patient population.<\/jats:p>","DOI":"10.3390\/jpm14020133","type":"journal-article","created":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T08:28:28Z","timestamp":1705998508000},"page":"133","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Lack of Association of Acne Severity with Depression, Anxiety, Stress, and Eating Attitudes: A Cross-Sectional Study"],"prefix":"10.3390","volume":"14","author":[{"given":"Mustafa","family":"Karaa\u011fa\u00e7","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Karaman Training and Research Hospital, 70200 Karaman, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanife Merve","family":"Ak\u00e7a","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine, Karamanoglu Mehmetbey University, 70200 Karaman, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6mer","family":"Acat","sequence":"additional","affiliation":[{"name":"Karaman Provincial Health Directorate, 70200 Karaman, T\u00fcrkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,1,23]]},"reference":[{"key":"ref_1","unstructured":"Gupta, K.A., and Jafferany, M. (2017). Disorders P. Comprehensive Textbook of Psychiatry, Wolters Kluwer."},{"key":"ref_2","first-page":"133","article-title":"The Impact of Pyschological Stress on Acne","volume":"25","author":"Mokos","year":"2017","journal-title":"Acta Dermatovenerol. Croat."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/bjd.13462","article-title":"A global perspective on the epidemiology of acne","volume":"172","author":"Tan","year":"2015","journal-title":"Br. J. Dermatol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/j.1529-8019.2006.00079.x","article-title":"Psychological problems in the acne patient","volume":"19","author":"Fried","year":"2006","journal-title":"Dermatol. Ther."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.clindermatol.2017.01.006","article-title":"Suicidal behaviors in the dermatology patient","volume":"35","author":"Gupta","year":"2017","journal-title":"Clin. Dermatol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1046\/j.1365-2133.1997.18131897.x","article-title":"Suicide in dermatological patients","volume":"137","author":"Cotterill","year":"1997","journal-title":"Br. J. Dermatol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1111\/j.1440-1754.2006.00979.x","article-title":"Acne, anxiety, depression and suicide in teenagers: A cross-sectional survey of New Zealand secondary school students","volume":"42","author":"Purvis","year":"2006","journal-title":"J. Paediatr. Child. Health"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"e12340","DOI":"10.1111\/appy.12340","article-title":"Stressful life events and psychiatric comorbidity in acne\u2014A case control study","volume":"11","author":"Bondade","year":"2019","journal-title":"Asia-Pac. Psychiatry"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1111\/j.1365-4632.2010.04726.x","article-title":"A multicenter epidemiological study of acne vulgaris in Korea","volume":"50","author":"Suh","year":"2011","journal-title":"Int. J. Dermatol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"131","DOI":"10.4103\/jfcm.jfcm_396_22","article-title":"Severity of acne, stress, and food habits of medical students at Taif University, Saudi Arabia","volume":"30","author":"Basfar","year":"2023","journal-title":"J. Fam. Community Med."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1001\/archderm.139.7.897","article-title":"The Response of Skin Disease to Stress: Changes in the Severity of Acne Vulgaris as Affected by Examination Stress","volume":"139","author":"Chiu","year":"2003","journal-title":"Arch. Dermatol."},{"key":"ref_12","first-page":"464","article-title":"Stressful Events and Serum Concentration of Substance P in Acne Patients","volume":"26","author":"Pawlaczyk","year":"2016","journal-title":"Ann. Dermatol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"85","DOI":"10.4236\/ojepi.2017.72008","article-title":"The Relationship between Eating Disorders and Stress among Medical Undergraduate: A Cross-Sectional Study","volume":"7","author":"Ngan","year":"2017","journal-title":"Open J. Epidemiol."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association (2013). Diagnostic and Statistical Manual of Mental Disorders, American Psychiatric Association.","DOI":"10.1176\/appi.books.9780890425596"},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Choi, J. (2020). Impact of Stress Levels on Eating Behaviors among College Students. Nutrients, 12.","DOI":"10.3390\/nu12051241"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"2176","DOI":"10.1111\/jocd.14330","article-title":"Could acne be a risk factor for developing eating disorders? Acne vulgaris and eating disorders","volume":"21","year":"2022","journal-title":"J. Cosmet. Dermatol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"2372","DOI":"10.1093\/jn\/134.9.2372","article-title":"The Three-Factor Eating Questionnaire-R18 Is Able to Distinguish among Different Eating Patterns in a General Population","volume":"134","author":"Romon","year":"2004","journal-title":"J. Nutr."},{"key":"ref_18","first-page":"229","article-title":"\u00dc\u00e7 fakt\u00f6rl\u00fc yeme \u00f6l\u00e7e\u011finin t\u00fcrk k\u00fclt\u00fcr\u00fcne uyarlanmas\u0131: Ge\u00e7erlik ve g\u00fcvenirlik \u00e7al\u0131\u015fmas\u0131","volume":"15","year":"2016","journal-title":"TAF Prev. Med. Bull."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0005-7967(94)00075-U","article-title":"The structure of negative emotional states: Comparison of the Depression Anxiety Stress Scales (DASS) with the Beck Depression and Anxiety Inventories","volume":"33","author":"Lovibond","year":"1995","journal-title":"Behav. Res. Ther."},{"key":"ref_20","first-page":"19","article-title":"The psychometric properties of Turkish version of Depression Anxiety Stress Scale-21 (DASS-21) in health control and clinical samples","volume":"7","year":"2018","journal-title":"JCBPR"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1046\/j.1365-4362.1997.00099.x","article-title":"A comparison of current acne grading systems and proposal of a novel system","volume":"36","author":"Doshi","year":"1997","journal-title":"Int. J. Dermatol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"999","DOI":"10.2147\/CCID.S302311","article-title":"Assessment of anxiety and depression in patients with acne vulgaris in medina: A case-control study","volume":"14","author":"Molla","year":"2021","journal-title":"Clin. Cosmet. Investig. Dermatol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0190-9622(88)70047-X","article-title":"Role of anxiety and anger in acne patients: A relationship with the severity of the disorder","volume":"18","author":"Wu","year":"1988","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_24","first-page":"287","article-title":"Prevalence of acne vulgaris in Auckland senior high school students","volume":"108","author":"Lello","year":"1995","journal-title":"N. Z. Med. J."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"660","DOI":"10.3906\/sag-1208-65","article-title":"Anxiety, depression, social phobia, and quality of life in Turkish patients with acne and their relationships with the severity of acne","volume":"43","author":"Deveci","year":"2013","journal-title":"Turk. J. Med. Sci."},{"key":"ref_26","first-page":"46","article-title":"Physiological biomarkers of chronic stress: A systematic review","volume":"15","author":"Noushad","year":"2021","journal-title":"Int. J. Health Sci."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1046\/j.1440-0960.2001.00489.x","article-title":"Research Report Perceptions of acne vulgaris in final year medical student written examination answers","volume":"42","author":"Green","year":"2001","journal-title":"Australas. J. Dermatol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"143","DOI":"10.22270\/ajprd.v11i3.1272","article-title":"The Impact of Stress on Acne","volume":"11","author":"Bhaijamal","year":"2023","journal-title":"Asian J. Pharm. Res. Dev."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1097\/YCO.0000000000000641","article-title":"Review of the burden of eating disorders: Mortality, disability, costs, quality of life, and family burden","volume":"33","author":"Hoek","year":"2020","journal-title":"Curr. Opin. Psychiatry"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1002\/erv.2725","article-title":"Family-based treatment for adolescent anorexia nervosa: What happens to rates of comorbid diagnoses?","volume":"28","author":"Trainor","year":"2020","journal-title":"Eur. Eat. Disord. Rev."},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Sander, J., Moessner, M., and Bauer, S. (2021). Depression, Anxiety and Eating Disorder-Related Impairment: Moderators in Female Adolescents and Young Adults. Int. J. Environ. Res. Public Health, 18.","DOI":"10.3390\/ijerph18052779"},{"key":"ref_32","first-page":"12926","article-title":"Prevalence of Eating Disorders and Its Associated Risk Factors in Students of a Medical College Hospital in South India","volume":"13","author":"Iyer","year":"2021","journal-title":"Cureus"},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Lopes Cortes, M., Andrade Louzado, J., Galv\u00e3o Oliveira, M., Moraes Bezerra, V., Mistro, S., Souto Medeiros, D., Arruda Soares, D., Oliveira Silva, K., Nicolaevna Kochergin, C., and Honorato dos Santos de Carvalho, V.C. (2021). Unhealthy Food and Psychological Stress: The Association between Ultra-Processed Food Consumption and Perceived Stress in Working-Class Young Adults. Int. J. Environ. Res. Public Health, 18.","DOI":"10.3390\/ijerph18083863"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1844","DOI":"10.1002\/eat.23366","article-title":"Increased rates of eating disorders and their symptoms in women with major depressive disorder and anxiety disorders","volume":"53","author":"Garcia","year":"2020","journal-title":"Int. J. Eat. Disord."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1017\/S0029665120000166","article-title":"Emotional eating and obesity in adults: The role of depression, sleep and genes","volume":"79","author":"Konttinen","year":"2020","journal-title":"Proc. Nutr. Soc."},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Al-Musharaf, S. (2020). Prevalence and Predictors of Emotional Eating among Healthy Young Saudi Women during the COVID-19 Pandemic. Nutrients, 12.","DOI":"10.3390\/nu12102923"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"105122","DOI":"10.1016\/j.appet.2021.105122","article-title":"Increased emotional eating during COVID-19 associated with lockdown, psychological and social distress","volume":"160","author":"Cecchetto","year":"2021","journal-title":"Appetite"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"70","DOI":"10.4162\/nrp.2020.14.1.70","article-title":"Factors affecting emotional eating and eating palatable food in adults","volume":"14","author":"Bilici","year":"2020","journal-title":"Nutr. Res. Pract."}],"container-title":["Journal of Personalized Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4426\/14\/2\/133\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T13:47:58Z","timestamp":1760104078000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4426\/14\/2\/133"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,23]]},"references-count":38,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,2]]}},"alternative-id":["jpm14020133"],"URL":"https:\/\/doi.org\/10.3390\/jpm14020133","relation":{},"ISSN":["2075-4426"],"issn-type":[{"value":"2075-4426","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,23]]}}}