{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:55:16Z","timestamp":1761746116392,"version":"build-2065373602"},"reference-count":60,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T00:00:00Z","timestamp":1746144000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>Background: Frontal sinus inverted papilloma (IP) is a particularly rare form of IP and its management is challenging, with a high rate of recurrence. Objectives: Our aim was to evaluate the recurrence rate of frontal sinus IP after surgery and compare this rate according to the surgical modality (purely endoscopic sinus surgery vs. a combined\/open approach). Design: A systematic review without meta-analysis conducted by a working group of the Young Otolaryngologists of the International Federation of Otorhinolaryngological Societies (yo-IFOS). Data Sources and Methods: A systematic analysis of the literature was performed and reported following the criteria laid down in the SWiM guidelines. The review was registered on Prospero, a dedicated software was used for screening (Covidence), and R (v.4.2.2) was used for statistical analysis. Eligible articles were studies reporting at least five cases of frontal sinus IP surgically treated. Results: A total of 2925 studies were identified based on the MeSH equation, and 39 studies were included (n = 642 patients). Among the studies included, the recurrence rate was 18.4% (118\/642) with a mean time to recurrence of 25.6 (\u00b111.7) months. The difference between surgical modalities was not statistically significant in terms of recurrence rate (14.7% vs. 16.5%; p = 0.675). Conclusions: The recurrence rate of frontal sinus IP is not different between surgical modalities. However, it does not reduce the need for a tailored therapeutic strategy, as other factors also need to be considered (time to recurrence, complications, quality of life) when choosing the most appropriate approach.<\/jats:p>","DOI":"10.3390\/jpm15050183","type":"journal-article","created":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T07:44:58Z","timestamp":1746171898000},"page":"183","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Endoscopic Sinus Surgery in Frontal Sinus Inverted Papilloma: A Systematic Review"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8317-2286","authenticated-orcid":false,"given":"Maxime","family":"Fieux","sequence":"first","affiliation":[{"name":"Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Service d\u2019ORL, d\u2019Otoneurochirurgie et de Chirurgie Cervico-Faciale, 69495 Pierre B\u00e9nite, France"},{"name":"Universit\u00e9 de Lyon, Universit\u00e9 Lyon 1, 69003 Lyon, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7999-951X","authenticated-orcid":false,"given":"Valentin","family":"Favier","sequence":"additional","affiliation":[{"name":"D\u00e9partement d\u2019ORL, Chirurgie Cervico Faciale et Maxillo-Faciale, H\u00f4pital Gui de Chauliac, CHU de Montpellier, 34295 Montpellier, France"},{"name":"Research-Team ICAR, Laboratory of Computer Science, Robotics and Microelectronics of Montpellier (LIRMM), Universit\u00e9 de Montpellier, French National Centre for Scientific Research (CNRS), 34095 Montpellier, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8877-8014","authenticated-orcid":false,"given":"Andre","family":"Sousa Machado","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Unidade Local de Sa\u00fade de Tr\u00e1s-os-Montes e Alto (ULSTMAD), CP 5000-508 Vila Real, Portugal"},{"name":"Faculty of Health Sciences, University of Beira Interior, CP 6200-506 Covilh\u00e3, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0952-0091","authenticated-orcid":false,"given":"Mikail","family":"Nourredine","sequence":"additional","affiliation":[{"name":"Service de Biostatistiques de Lyon, P\u00f4le Sant\u00e9 Publique, Hospices Civil de Lyon, 69002 Lyon, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7947-9437","authenticated-orcid":false,"given":"Caroline","family":"Giroudon","sequence":"additional","affiliation":[{"name":"Service de la Documentation Centrale, Hospices Civils de Lyon, 69424 Lyon, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5574-8559","authenticated-orcid":false,"given":"Florent","family":"Carsuzaa","sequence":"additional","affiliation":[{"name":"Service ORL, Chirurgie Cervico-Maxillo-Faciale et Audiophonologie, Centre Hospitalier Universitaire de Poitiers, 86000 Poitiers, France"},{"name":"Laboratoire Inflammation Tissus Epith\u00e9liaux et Cytokines (LITEC), UR15560, Universit\u00e9 de Poitiers, 86000 Poitiers, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paresh P.","family":"Naik","sequence":"additional","affiliation":[{"name":"Jaslok Hospital & Research Centre, Pedder Road, Mumbai, Maharashtra 400026, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"the yo-IFOS Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,5,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.wjorl.2016.11.004","article-title":"Etiology of Sinonasal Inverted Papilloma: A Narrative Review","volume":"3","author":"Wang","year":"2017","journal-title":"World J. 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