{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:31:18Z","timestamp":1760059878591,"version":"build-2065373602"},"reference-count":63,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T00:00:00Z","timestamp":1752537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>Background: Awake craniotomy (AC) surgeries are less common in the pediatric population in comparison to their adult counterparts. Nonetheless, they can be considered for selected cases whereby speech preservation is paramount during maximal safe resection of intracranial lesions. We describe a case of AC for the excision of a brain arteriovenous malformation (bAVM) with language mapping in a pediatric patient. Methods: A previously well 16-year-old male presented with a spontaneous left frontal intracranial hemorrhage. Neuroimaging confirmed the cause to be a left antero-temporal bAVM centered in the insula. A decision was made for AC bAVM excision with language mapping for speech preservation. Results: As part of the pre-operative preparation, the patient and his caregivers were reviewed by a multidisciplinary team. For the conduct of the AC, the asleep\u2013awake\u2013asleep technique was used with processed EEG to guide anesthesia management. Additional modifications to make the patient comfortable included the avoidance of rigid cranial skull pins, urinary catheterization and central line insertion at the start of the surgery. Conclusions: Our experience concurs with the evidence that AC in children is a feasible option for select individuals. To our knowledge, this is the first detailed case description of a pediatric patient undergoing AC with language mapping for a bAVM. Emphases include a strong rapport between the patient and the managing multidisciplinary team, flexibility to adjust conventional workflows and limitations of neuroimaging adjuncts.<\/jats:p>","DOI":"10.3390\/jpm15070319","type":"journal-article","created":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T15:01:05Z","timestamp":1752591665000},"page":"319","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Awake Craniotomy for the Excision of a Pediatric Cerebral Arteriovenous Malformation for Language Preservation: A Case Description"],"prefix":"10.3390","volume":"15","author":[{"given":"Melody","family":"Long","sequence":"first","affiliation":[{"name":"Department of Pediatric Anesthesia, KK Women\u2019s and Children\u2019s Hospital, 100 Bukit Timah Road, Singapore 229899, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Thiaghu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Intensive Care and Pain Medicine, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tien Meng","family":"Cheong","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramez W.","family":"Kirollos","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4255-8136","authenticated-orcid":false,"given":"Lee Ping","family":"Ng","sequence":"additional","affiliation":[{"name":"Neurosurgical Service, KK Women\u2019s and Children\u2019s Hospital, 100 Bukit Timah Road, Singapore 229899, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7317-670X","authenticated-orcid":false,"given":"Sharon Y. Y.","family":"Low","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore"},{"name":"Neurosurgical Service, KK Women\u2019s and Children\u2019s Hospital, 100 Bukit Timah Road, Singapore 229899, Singapore"},{"name":"SingHealth Duke-NUS Neuroscience Academic Clinical Program, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore"},{"name":"SingHealth Duke-NUS Pediatrics Academic Clinical Program, 100 Bukit Timah Road, Singapore 229899, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,7,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1159\/000447605","article-title":"Arteriovenous Malformations in the Pediatric Population: Review of the Existing Literature","volume":"5","author":"Alderazi","year":"2016","journal-title":"Interv. Neurol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1227\/00006123-198503000-00026","article-title":"Natural history of intracranial vascular malformations: A review","volume":"16","author":"Wilkins","year":"1985","journal-title":"Neurosurgery"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1227\/NEU.0b013e3182181c00","article-title":"Management of pediatric intracranial arteriovenous malformations: Experience with multimodality therapy","volume":"69","author":"Darsaut","year":"2011","journal-title":"Neurosurgery"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1212\/WNL.0b013e31825182c5","article-title":"Radiosurgery for unruptured cerebral arteriovenous malformations: Long-term seizure outcome","volume":"78","author":"Yang","year":"2012","journal-title":"Neurology"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"437","DOI":"10.3171\/2012.10.JNS121280","article-title":"Natural history of cerebral arteriovenous malformations: A meta-analysis","volume":"118","author":"Gross","year":"2013","journal-title":"J. Neurosurg."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1161\/STROKEAHA.108.524678","article-title":"The natural history and predictive features of hemorrhage from brain arteriovenous malformations","volume":"40","author":"Wallace","year":"2009","journal-title":"Stroke"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"106283","DOI":"10.1016\/j.jstrokecerebrovasdis.2021.106283","article-title":"Paediatric Cerebral Arteriovenous Malformation: Outcomes from a Singapore Children\u2019s Hospital","volume":"31","author":"Lim","year":"2022","journal-title":"J. Stroke Cerebrovasc. Dis."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1136\/jnis-2023-020650","article-title":"Re-rupture in ruptured brain arteriovenous malformations: A retrospective cohort study based on a nationwide multicenter prospective registry","volume":"16","author":"Yuan","year":"2024","journal-title":"J. NeuroInterventional Surg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1097\/00006123-200008000-00015","article-title":"Multimodality treatment of nongalenic arteriovenous malformations in pediatric patients","volume":"47","author":"Hoh","year":"2000","journal-title":"Neurosurgery"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s007010050017","article-title":"Cerebral arteriovenous malformations in children","volume":"142","author":"Tamburrini","year":"2000","journal-title":"Acta Neurochir"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s00381-004-1025-0","article-title":"Surgical results in pediatric Spetzler-Martin grades I-III intracranial arteriovenous malformations","volume":"21","author":"Kiris","year":"2005","journal-title":"Childs Nerv. Syst."},{"key":"ref_12","first-page":"82","article-title":"Superior outcomes in children compared with adults after microsurgical resection of brain arteriovenous malformations","volume":"105","author":"Chennupati","year":"2006","journal-title":"J. Neurosurg."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1093\/neuros\/nyaa440","article-title":"Clinical Pearls and Methods for Intraoperative Awake Language Mapping","volume":"89","author":"Morshed","year":"2021","journal-title":"Neurosurgery"},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Duffau, H. (2011). Awake Mapping and Tumor Surgery. Brain Mapping: From Neural Basis of Cognition to Surgical Applications, Springer.","DOI":"10.1007\/978-3-7091-0723-2_24"},{"key":"ref_15","first-page":"397","article-title":"Diffusion tensor imaging magnetic resonance imaging (DTI-MRI) helps to tailor speech therapy: A case report with a short narrative review","volume":"53","author":"Muccio","year":"2023","journal-title":"NeuroRehabilitation"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1007\/BF03010852","article-title":"Conscious-sedation analgesia during craniotomy for intractable epilepsy: A review of 354 consecutive cases","volume":"35","author":"Archer","year":"1988","journal-title":"Can. J. Anaesth."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1111\/jon.12283","article-title":"The DTI Challenge: Toward Standardized Evaluation of Diffusion Tensor Imaging Tractography for Neurosurgery","volume":"25","author":"Pujol","year":"2015","journal-title":"J. Neuroimaging"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.wneu.2013.01.116","article-title":"The dangers of magnetic resonance imaging diffusion tensor tractography in brain surgery","volume":"81","author":"Duffau","year":"2014","journal-title":"World Neurosurg."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1227\/NEU.0b013e31820c02a3","article-title":"Awake craniotomy vs surgery under general anesthesia for resection of supratentorial lesions","volume":"68","author":"Sacko","year":"2011","journal-title":"Neurosurgery"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.wneu.2023.10.032","article-title":"Awake Craniotomy in Pediatric Patients: A Meta-analysis of Operative Outcomes","volume":"181","author":"Lu","year":"2024","journal-title":"World Neurosurg."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"428","DOI":"10.3171\/2023.4.PEDS22296","article-title":"Awake craniotomies in the pediatric population: A systematic review","volume":"32","author":"Bhanja","year":"2023","journal-title":"J. Neurosurg. Pediatr."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1016\/j.bja.2018.01.018","article-title":"Pharmacokinetic-pharmacodynamic model for propofol for broad application in anaesthesia and sedation","volume":"120","author":"Eleveld","year":"2018","journal-title":"Br. J. Anaesth."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"289","DOI":"10.4097\/kja.23843","article-title":"Intraoperative pediatric electroencephalography monitoring: An updated review","volume":"77","author":"Yuan","year":"2024","journal-title":"Korean J. Anesthesiol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1097\/ALN.0000000000000841","article-title":"Clinical Electroencephalography for Anesthesiologists: Part I: Background and Basic Signatures","volume":"123","author":"Purdon","year":"2015","journal-title":"Anesthesiology"},{"key":"ref_25","first-page":"e14960","article-title":"Mapping of the Language Cortex","volume":"13","author":"Jahangiri","year":"2021","journal-title":"Cureus"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/B978-0-444-64032-1.00020-5","article-title":"Chapter 20\u2014Electrocorticography and Functional Mapping","volume":"Volume 160","author":"Levin","year":"2019","journal-title":"Handbook of Clinical Neurology"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1136\/neurintsurg-2021-017777","article-title":"Pediatric brain arteriovenous malformation recurrence: A cohort study, systematic review and meta-analysis","volume":"14","author":"Hak","year":"2022","journal-title":"J. Neurointerv. Surg."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"677","DOI":"10.3171\/2021.6.PEDS21227","article-title":"Return of the lesion: A meta-analysis of 1134 angiographically cured pediatric arteriovenous malformations","volume":"28","author":"Lauzier","year":"2021","journal-title":"J. Neurosurg. Pediatr."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1097\/00004311-198602430-00013","article-title":"Anesthetic considerations for craniotomy in awake patients","volume":"24","author":"Manninen","year":"1986","journal-title":"Int. Anesthesiol. Clin."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.wneu.2023.08.040","article-title":"Awake Craniotomy Surgery in Pediatrics: A Systematic Review","volume":"179","author":"Madan","year":"2023","journal-title":"World Neurosurg."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1007\/s00381-016-3069-3","article-title":"Awake surgery for hemispheric low-grade gliomas: Oncological, functional and methodological differences between pediatric and adult populations","volume":"32","author":"Trevisi","year":"2016","journal-title":"Childs Nerv. Syst."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1159\/000442988","article-title":"Pediatric Awake Craniotomy for Brain Lesions","volume":"51","author":"Akay","year":"2016","journal-title":"Pediatr. Neurosurg."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"E5","DOI":"10.3171\/2019.11.FOCUS19774","article-title":"Development and implementation of a novel child life protocol to enhance psychosocial support for pediatric awake craniotomies: Technical note","volume":"48","author":"McDowell","year":"2020","journal-title":"Neurosurg. Focus"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"453","DOI":"10.25259\/SNI_192_2024","article-title":"Awake resection of a right motor cortex arteriovenous malformation in a pediatric patient: A case report and review of the literature","volume":"15","author":"Nadeem","year":"2024","journal-title":"Surg. Neurol. Int."},{"key":"ref_35","first-page":"6902075","article-title":"Awake Craniotomy in a Child: Assessment of Eligibility with a Simulated Theatre Experience","volume":"2020","author":"Labuschagne","year":"2020","journal-title":"Case Rep. Anesthesiol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s00381-019-04308-8","article-title":"Psychological aspects of awake brain surgery in children-interests and risks","volume":"36","author":"Huguet","year":"2020","journal-title":"Childs Nerv. Syst."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1007\/s00381-020-04522-9","article-title":"Awake brain surgery in children\u2014A single-center experience","volume":"36","author":"Lohkamp","year":"2020","journal-title":"Child\u2019s Nerv. Syst."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.bja.2020.10.027","article-title":"Prospective clinical validation of the Eleveld propofol pharmacokinetic-pharmacodynamic model in general anaesthesia","volume":"126","author":"Vellinga","year":"2021","journal-title":"Br. J. Anaesth."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1046\/j.1365-2044.2000.01277.x","article-title":"Target-controlled infusion of propofol and remifentanil combined with bispectral index monitoring for awake craniotomy","volume":"55","author":"Hans","year":"2000","journal-title":"Anaesthesia"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"274","DOI":"10.29011\/2574-7754\/100274","article-title":"Anesthetic Technique During Awake Craniotomy-A Case Report","volume":"12","author":"Wang","year":"2019","journal-title":"Ann. Case Rep."},{"key":"ref_41","first-page":"47","article-title":"Alternate Electrode Placements to Facilitate Frontal Electroencephalography Monitoring in Anesthetized and Critically Ill Patients","volume":"37","author":"Ahmed","year":"2024","journal-title":"J. Neurosurg. Anesthesiol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.neuchi.2016.08.009","article-title":"Direct electrical bipolar electrostimulation for functional cortical and subcortical cerebral mapping in awake craniotomy. Practical considerations","volume":"63","author":"Pallud","year":"2017","journal-title":"Neurochirurgie"},{"key":"ref_43","first-page":"e15861","article-title":"Asleep Speech Mapping Using Orofacial Muscles as Surrogates for Motor Speech in Patients Who Cannot Tolerate Awake Surgery: A Case Series","volume":"13","author":"Bonda","year":"2021","journal-title":"Cureus"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1097\/00006123-199608000-00020","article-title":"Transcranial high-frequency repetitive electrical stimulation for recording myogenic motor evoked potentials with the patient under general anesthesia","volume":"39","author":"Pechstein","year":"1996","journal-title":"Neurosurgery"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1053\/j.sult.2014.06.008","article-title":"White Matter Tracts of Speech and Language","volume":"35","author":"Smits","year":"2014","journal-title":"Semin. Ultrasound CT MRI"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"3095","DOI":"10.1007\/s00415-024-12358-5","article-title":"The role of language-related functional brain regions and white matter tracts in network plasticity of post-stroke aphasia","volume":"271","author":"Han","year":"2024","journal-title":"J. Neurol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.yebeh.2016.04.021","article-title":"Functional differences among stimulation-identified cortical naming sites in the temporal region","volume":"60","author":"Hamberger","year":"2016","journal-title":"Epilepsy Behav."},{"key":"ref_48","first-page":"1423","article-title":"Plasticity of the human motor cortex in patients with arteriovenous malformations: A functional MR imaging study","volume":"21","author":"Alkadhi","year":"2000","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1212\/WNL.49.3.802","article-title":"Anterior translocation of language in patients with left cerebral arteriovenous malformation","volume":"49","author":"Lazar","year":"1997","journal-title":"Neurology"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1016\/j.wneu.2015.01.040","article-title":"Brain Mapping for Safe Microsurgical Resection of Arteriovenous Malformations in Eloquent Cortex","volume":"83","author":"Stapleton","year":"2015","journal-title":"World Neurosurg."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1227\/01.NEU.0000255401.46151.8A","article-title":"The effects of diffuseness and deep perforating artery supply on outcomes after microsurgical resection of brain arteriovenous malformations","volume":"60","author":"Du","year":"2007","journal-title":"Neurosurgery"},{"key":"ref_52","doi-asserted-by":"crossref","unstructured":"Salama, G.R., Heier, L.A., Patel, P., Ramakrishna, R., Magge, R., and Tsiouris, A.J. (2018). Diffusion Weighted\/Tensor Imaging, Functional MRI and Perfusion Weighted Imaging in Glioblastoma\u2014Foundations and Future. Front. Neurol., 8.","DOI":"10.3389\/fneur.2017.00660"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.3171\/2014.10.JNS14945","article-title":"Intraoperative subcortical mapping of a language-associated deep frontal tract connecting the superior frontal gyrus to Broca\u2019s area in the dominant hemisphere of patients with glioma","volume":"122","author":"Fujii","year":"2015","journal-title":"J. Neurosurg. JNS"},{"key":"ref_54","first-page":"43","article-title":"The usefulness and limitations of diffusion tensor imaging -a review study","volume":"2","year":"2019","journal-title":"Eur. J. Transl. Clin. Med."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"177","DOI":"10.4103\/sni.sni_24_18","article-title":"Awake craniotomy without sedation in treatment of patients with lesional epilepsy","volume":"9","author":"Sitnikov","year":"2018","journal-title":"Surg. Neurol. Int."},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"Soldozy, S., Akyeampong, D.K., Barquin, D.L., Norat, P., Ya\u011fmurlu, K., Sokolowski, J.D., Sharifi, K.A., Tvrdik, P., Park, M.S., and Kalani, M.Y.S. (2020). Systematic Review of Functional Mapping and Cortical Reorganization in the Setting of Arteriovenous Malformations, Redefining Anatomical Eloquence. Front. Surg., 7.","DOI":"10.3389\/fsurg.2020.514247"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/jcbfm.2014.179","article-title":"Biology of cerebral arteriovenous malformations with a focus on inflammation","volume":"35","author":"Mouchtouris","year":"2015","journal-title":"J. Cereb. Blood Flow. Metab."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1227\/01.NEU.0000134384.94749.B2","article-title":"Lesion-induced pseudo-dominance at functional magnetic resonance imaging: Implications for preoperative assessments","volume":"55","author":"Ulmer","year":"2004","journal-title":"Neurosurgery"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/S1567-4231(07)08008-2","article-title":"Direct Cortical Stimulation to Localize Sensory, Motor and Language Function","volume":"Volume 8","author":"Schrader","year":"2008","journal-title":"Handbook of Clinical Neurophysiology"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.jocn.2019.06.042","article-title":"The Stony Brook awake craniotomy protocol: A technical note","volume":"67","author":"Shen","year":"2019","journal-title":"J. Clin. Neurosci."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1111\/pan.15075","article-title":"Pediatric Awake Craniotomy: An Educational Review","volume":"35","author":"Henry","year":"2025","journal-title":"Paediatr. Anaesth."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"ii1","DOI":"10.1093\/neuonc\/not151","article-title":"CBTRUS statistical report: Primary brain and central nervous system tumors diagnosed in the United States in 2006-2010","volume":"15","author":"Ostrom","year":"2013","journal-title":"Neuro Oncol."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1016\/j.jocn.2015.04.013","article-title":"Awake craniotomy using electromagnetic navigation technology without rigid pin fixation","volume":"22","author":"Morsy","year":"2015","journal-title":"J. Clin. Neurosci."}],"container-title":["Journal of Personalized Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4426\/15\/7\/319\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T18:10:16Z","timestamp":1760033416000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4426\/15\/7\/319"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,15]]},"references-count":63,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2025,7]]}},"alternative-id":["jpm15070319"],"URL":"https:\/\/doi.org\/10.3390\/jpm15070319","relation":{},"ISSN":["2075-4426"],"issn-type":[{"type":"electronic","value":"2075-4426"}],"subject":[],"published":{"date-parts":[[2025,7,15]]}}}