{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T07:43:42Z","timestamp":1782805422285,"version":"3.54.5"},"reference-count":27,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>Objective: To review the literature on palliative care protocols and models of care for pregnant women and their fetuses with life-limiting conditions. Methods: A narrative literature review was conducted in the PubMed\/MEDLINE and Virtual Health Library (VHL)\u2014BIREME\/SciELO\/LILACS, using the descriptors \u201cpalliative care\u201d and \u201cprenatal care\u201d. Studies of all designs published between February 2015 and May 2025 were considered for inclusion. Articles in languages other than Portuguese, English, and Spanish, duplicates, and those that did not discuss care protocols or experiences in perinatal palliative care for life-limiting fetal conditions starting from prenatal care were excluded. Articles were selected through title, abstract, and full-text screening. Results: Twenty-one studies focused on prenatal care were selected, presenting protocols and experiences of care in palliative fetal medicine. Most addressed the diagnosis of life-limiting fetal malformations, prenatal care, birth and delivery plan, perinatal grief and the puerperium. Across the included studies, a recurring emphasis on individualized, patient and family-centered approaches was identified, reflecting core principles of personalized medicine. Tailoring communication, care planning, and bereavement support to the specific clinical, genetic, cultural, and psychosocial profile of each dyad emerged as a structural characteristic of effective perinatal palliative care models. Conclusions: There is a scarcity of specific palliative care protocols for pregnancy, indicating a need to expand studies. The reviewed literature can contribute to the creation and adaptation of palliative care protocols and models for pregnant women and their fetuses with life-limiting conditions, may support more consistent care planning, improved communication, and better alignment with parental values.<\/jats:p>","DOI":"10.3390\/jpm16070353","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T05:58:04Z","timestamp":1782799084000},"page":"353","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Models of Perinatal Palliative Care for Pregnant Women and Their Fetuses with Life-Limiting Conditions: A Literature Review"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2222-6858","authenticated-orcid":false,"given":"Daniela Valle Almeida","family":"Figueredo","sequence":"first","affiliation":[{"name":"Service of Fetal Medicine, Institute of Integral Medicine Prof. Fernando Figueira (IMIP), Recife 50070-555, PE, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia de Lourdes Loreto","family":"Faquini","sequence":"additional","affiliation":[{"name":"Service of Fetal Medicine, Institute of Integral Medicine Prof. Fernando Figueira (IMIP), Recife 50070-555, PE, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6145-2532","authenticated-orcid":false,"given":"Edward","family":"Araujo J\u00fanior","sequence":"additional","affiliation":[{"name":"Discipline of Woman Health, Municipal University de S\u00e3o Caetano do Sul (USCS), S\u00e3o Caetano do Sul 09521-160, SP, Brazil"},{"name":"Department of Obstetrics, Paulista School of Medicine-Federal University of S\u00e3o Paulo (EPM-UNIFESP), S\u00e3o Paulo 04023-062, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1257-5752","authenticated-orcid":false,"given":"Tammy Caram","family":"Sabatine","sequence":"additional","affiliation":[{"name":"Discipline of Woman Health, Municipal University de S\u00e3o Caetano do Sul (USCS), S\u00e3o Caetano do Sul 09521-160, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6694-6569","authenticated-orcid":false,"given":"Gustavo Yano","family":"Callado","sequence":"additional","affiliation":[{"name":"Faculdade Israelita de Ci\u00eancias da Sa\u00fade Albert Einstein, Hospital Israelita Albert Einstein, S\u00e3o Paulo 05652-900, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2942-6182","authenticated-orcid":false,"given":"Antonio","family":"Braga","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, School of Medicine, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro 22240-003, RJ, Brazil"},{"name":"Department of General and Specialized Surgery, School of Medicine and Surgery, Federal University of the State of Rio de Janeiro (UNIRIO), Rio de Janeiro 22290-240, RJ, Brazil"},{"name":"Postgraduate Program in Applied Health Sciences, University of Vassouras (Univassouras), Vassouras 27700-000, RJ, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0318-9390","authenticated-orcid":false,"given":"Roberta","family":"Granese","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Dental Sciences and Morphofunctional Imaging, \u201cG. Martino\u201d University Hospital, 98100 Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7039-2052","authenticated-orcid":false,"given":"Alex Sandro Rolland","family":"Souza","sequence":"additional","affiliation":[{"name":"Service of Fetal Medicine, Institute of Integral Medicine Prof. Fernando Figueira (IMIP), Recife 50070-555, PE, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,30]]},"reference":[{"key":"ref_1","unstructured":"D\u2019Alessandro, M.P.S., Barbosa, L.C., Anagusko, S.S., Maiello, A.P.M.V., Conrado, C.M., Pires, C.T., and Forte, D.N. (2020). Manual de Cuidados Paliativos, Minist\u00e9rio da Sa\u00fade."},{"key":"ref_2","first-page":"421","article-title":"The application of hospice concepts to neonatal care","volume":"136","author":"Whitfield","year":"1982","journal-title":"Am. J. Dis. 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