{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T04:23:38Z","timestamp":1760243018878,"version":"build-2065373602"},"reference-count":54,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2015,5,28]],"date-time":"2015-05-28T00:00:00Z","timestamp":1432771200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JPM"],"abstract":"<jats:p>This study explored breast cancer survivors\u2019 perspectives regarding their experiences of the survivorship continuum from diagnosis through 30 months post-treatment. The sample included women (N = 379) with newly-diagnosed breast cancer undergoing treatment at a Midwestern university-affiliated cancer center. Semi-structured interviews were conducted using the Lymphedema and Breast Cancer Questionnaire at time of diagnosis, post-operatively, quarterly during the first year, and then semi-annually thereafter through 30 months post-treatment. A mixed-methodology was used to analyze participants\u2019 comments. Themes central to long-term survivorship experiences included social support, positive worldviews, breast cancer and lymphedema health literacy, religious\/spiritual beliefs,  self-empowerment, and recovery expectations. These themes were consistent with a psychoneuroimmunological model of health in which psychosocial variables mediate stress and influence health outcomes. Qualitative data showed that social support and positive worldviews were the two themes with the most significant impact on long-term breast cancer survivorship experiences. Survivors expressed a need to advance their health care literacy in order to share ownership of breast cancer and lymphedema treatment decisions. Since breast cancer is an immune-mediated disease, long-term survivorship planning should address psychosocial factors that influence the long-term psychological distress associated with immune dysfunction.<\/jats:p>","DOI":"10.3390\/jpm5020174","type":"journal-article","created":{"date-parts":[[2015,5,28]],"date-time":"2015-05-28T11:01:49Z","timestamp":1432810909000},"page":"174-190","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Perspectives of the Breast Cancer Survivorship Continuum: Diagnosis through 30 Months Post-Treatment"],"prefix":"10.3390","volume":"5","author":[{"given":"Jennifer","family":"Hulett","sequence":"first","affiliation":[{"name":"Sinclair School of Nursing, Ellis Fischel Cancer Center, University of Missouri-Columbia,  DC 116.05 Suite 408 Mizzou North, University of Missouri, Columbia, MO 65211, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane","family":"Armer","sequence":"additional","affiliation":[{"name":"Sinclair School of Nursing, Ellis Fischel Cancer Center, University of Missouri-Columbia,  DC 116.05 Suite 408 Mizzou North, University of Missouri, Columbia, MO 65211, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bob","family":"Stewart","sequence":"additional","affiliation":[{"name":"Sinclair School of Nursing, Ellis Fischel Cancer Center, University of Missouri-Columbia,  DC 116.05 Suite 408 Mizzou North, University of Missouri, Columbia, MO 65211, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ausanee","family":"Wanchai","sequence":"additional","affiliation":[{"name":"Sinclair School of Nursing, Ellis Fischel Cancer Center, University of Missouri-Columbia,  DC 116.05 Suite 408 Mizzou North, University of Missouri, Columbia, MO 65211, USA"},{"name":"Boromarajonani College of Nursing Buddhachinaraj, Muang, Phitsanulok 65000, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2015,5,28]]},"reference":[{"key":"ref_1","unstructured":"American Cancer Society Breast Cancer: Facts and Figures 2011\u20132012. Available online: http:\/\/www.cancer.org\/research\/cancerfactsfigures\/breastcancerfactsfigures\/breast-cancer-facts-and-figures-2011\u20132012."},{"key":"ref_2","unstructured":"Howlader, N., Noone, A.M., Krapcho, M., Garshell, J., Miller, D., Altekruse, S.F., Kosary, C.L., Yu, M., Ruhl, J., and Tatalovich, Z. SEER Cancer Statistics Review, 1975\u20132011, Available online: http:\/\/seer.cancer.gov\/csr\/1975_2011."},{"key":"ref_3","unstructured":"National Cancer Institute Cancer Trends Progress Report\u20142011\u20132012 Update, Available online: http:\/\/progressreport.cancer.gov."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"163","DOI":"10.2190\/PM.40.2.c","article-title":"It\u2019s not over when it\u2019s over: Long-term symptoms in cancer survivors\u2014A systematic review","volume":"40","author":"Harrington","year":"2010","journal-title":"Int. J. Psychiatry Med."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1111\/j.1524-4741.2009.00878.x","article-title":"Older breast cancer survivors: Factors associated with self-reported symptoms of persistent lymphedema over 7 years of follow-up","volume":"16","author":"Ganz","year":"2010","journal-title":"Breast J."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1111\/j.1365-2354.2008.01001.x","article-title":"Psychosocial implications of living 5 years or more following a cancer diagnosis: A systematic review of the research evidence","volume":"18","author":"Foster","year":"2009","journal-title":"Eur. J. Cancer Care"},{"key":"ref_7","first-page":"1466","article-title":"Psychosocial impact of lymphedema: A systematic review of literature from 2004 to 2011","volume":"7","author":"Fu","year":"2012","journal-title":"Psychooncology"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1111\/bjh.12698","article-title":"Psychosocial factors associated with impact of cancer in longterm haematological cancer survivors","volume":"164","author":"Korszun","year":"2014","journal-title":"Br. J. Haematol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1002\/pon.1965","article-title":"Quality of life of younger breast cancer survivors: persistence of problems and sense of well-being","volume":"21","author":"Bloom","year":"2012","journal-title":"Psychooncology"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s11764-011-0197-3","article-title":"Fatigue and quality of life in breast cancer survivors: Temporal courses and long-term pattern","volume":"6","author":"Schmidt","year":"2012","journal-title":"J. Cancer Surviv."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.psyneuen.2006.09.011","article-title":"Psychologic stress, reduced NK cell activity, and cytokine dysregulation in women experiencing diagnostic breast biopsy","volume":"32","author":"Gabram","year":"2007","journal-title":"Psychoneuroendocrinology"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.3109\/0284186X.2013.774461","article-title":"Quality of life in long-term breast cancer survivors-a 10 year longitudinal population-based study","volume":"52","author":"Koch","year":"2013","journal-title":"Acta Oncol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1007\/s11764-013-0272-z","article-title":"Fear of cancer recurrence in adult cancer survivors: A systematic review of quantitative studies","volume":"7","author":"Simard","year":"2013","journal-title":"J. Cancer Surviv."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s12609-010-0009-1","article-title":"Lymphedema: How do we diagnose and reduce the risk of this dreaded complication of breast cancer treatment?","volume":"2","author":"Bernas","year":"2010","journal-title":"Curr. Breast Cancer Rep."},{"key":"ref_15","first-page":"118","article-title":"Post-breast cancer lymphedema: Incidence increases from 12 to 30 to 60 months","volume":"43","author":"Armer","year":"2010","journal-title":"Lymphology"},{"key":"ref_16","first-page":"14","article-title":"30-month post-breast cancer treatment lymphoedema","volume":"4","author":"Armer","year":"2009","journal-title":"J. Lymphoedema."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.breast.2012.01.013","article-title":"Factors associated with long-term functional outcomes and psychological sequelae in women after breast cancer","volume":"21","author":"Khan","year":"2012","journal-title":"Breast J."},{"key":"ref_18","first-page":"49","article-title":"Complementary therapies in the management of cancer treatment-related symptoms: The individualized prescriptive exercise intervention approach","volume":"10","author":"Battaglini","year":"2006","journal-title":"Med. Sport."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1188\/10.ONF.85-91","article-title":"Patient perceptions of arm care and exercise advice after breast cancer surgery","volume":"37","author":"Lee","year":"2010","journal-title":"Oncol. Nurs. Forum"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1002\/cncr.21195","article-title":"Psychologic and social sequelae of secondary lymphedema","volume":"104","author":"McWayne","year":"2005","journal-title":"Cancer"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1089\/lrb.2009.0004","article-title":"The psycho-social impact of lymphedema","volume":"7","author":"Ridner","year":"2009","journal-title":"Lymphat. Res. Biol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1007\/s00520-004-0770-7","article-title":"Prevalence of complementary and alternative medicine use in cancer patients during treatment","volume":"13","author":"Yates","year":"2005","journal-title":"Support. Care Cancer"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1188\/10.ONF.494-500","article-title":"Breast cancer survivors\u2019 perspectives of care practices in western and alternative medicine","volume":"37","author":"Wanchai","year":"2010","journal-title":"Oncol. Nurs. Forum"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1007\/s10865-011-9314-z","article-title":"View of God as benevolent and forgiving or punishing and judgmental predicts HIV disease progression","volume":"34","author":"Ironson","year":"2011","journal-title":"J. Behav. Med."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Koenig, H.G., McCullough, M., and Larson, D.B. (2000). Handbook of Religion and Health, Oxford University Press.","DOI":"10.1093\/acprof:oso\/9780195118667.001.0001"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1007\/s11764-011-0193-7","article-title":"Twenty-five years later\u2014What do we know about religion\/spirituality and psychological well-being among breast cancer survivors? A systematic review","volume":"6","author":"Schreiber","year":"2012","journal-title":"J. Cancer Surviv."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1007\/s11136-014-0654-3","article-title":"\u201cWe both just trusted and leaned on the Lord\u201d: A qualitative study of religiousness and spirituality among African American breast cancer survivors and their caregivers","volume":"23","author":"Sterba","year":"2014","journal-title":"Qual. Life Res."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1089\/lrb.2005.3.208","article-title":"A comparison of four diagnostic criteria for lymphedema in a post-breast cancer population","volume":"3","author":"Armer","year":"2005","journal-title":"Lymphat Res. Biol."},{"key":"ref_29","first-page":"161","article-title":"Minimal limb volume change has a significant impact on breast cancer survivors","volume":"42","author":"Cormier","year":"2009","journal-title":"Lymphology"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1097\/00006199-200311000-00004","article-title":"Predicting breast cancer-related lymphedema using self-reported symptoms","volume":"52","author":"Armer","year":"2003","journal-title":"Nurs. Res."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"14","DOI":"10.3102\/0013189X033007014","article-title":"Mixed methods research: A research paradigm whose time has come","volume":"33","author":"Johnson","year":"2004","journal-title":"Educ. Res."},{"key":"ref_32","unstructured":"Strauss, A., and Corbin, J. (1998). Basics of Qualitative Research: Techniques and Procedures for Developing Grounded Theory, Sage. [2nd ed.]."},{"key":"ref_33","unstructured":"Charmaz, K. (2006). Constructing Grounded Theory: A Practical Guide through Qualitative Research, Sage."},{"key":"ref_34","unstructured":"Salda\u00f1a, J. (2012). The Coding Manual for Qualitative Researchers, SAGE Publications Ltd."},{"key":"ref_35","unstructured":"Miles, M.B., and Huberman, A.M. (1994). Qualitative Data Analysis, SAGE. [2nd ed.]."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s10865-006-9056-5","article-title":"Social support and health: A review of physiological processes potentially underlying links to disease outcomes","volume":"29","author":"Uchino","year":"2006","journal-title":"J. Behav. Med."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1002\/pon.3480","article-title":"Social support, self-efficacy for decision-making, and follow-up care use in long-term cancer survivors","volume":"23","author":"Forsythe","year":"2014","journal-title":"Psychooncology"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.psyneuen.2013.12.016","article-title":"Social support predicts inflammation, pain, and depressive symptoms: Longitudinal relationships among breast cancer survivors","volume":"42","author":"Hughes","year":"2014","journal-title":"Psychoneuroendocrinology"},{"key":"ref_39","unstructured":"Huyssteen, J. (2003). Encyclopedia of Science and Religion, MacMillan."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1037\/a0034416","article-title":"Differing pathways between religiousness, spirituality, and health: A self-regulation perspective","volume":"6","author":"Aldwin","year":"2014","journal-title":"Psychol. Relig. Spiritual."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1080\/02699050902788501","article-title":"Relationships among spiritual beliefs, religious practices, congregational support and health for individuals with traumatic brain injury","volume":"23","author":"Johnstone","year":"2009","journal-title":"Brain Inj."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1037\/a0015883","article-title":"The empirical and conceptual value of the spiritual transcendence and religious involvement scales for personality research","volume":"1","author":"Piedmont","year":"2009","journal-title":"Psychol. Relig. Spiritual."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1037\/a0030813","article-title":"Religiousness\/spirituality, cardiovascular disease, and cancer: Cultural integration for health research and intervention","volume":"81","author":"Masters","year":"2013","journal-title":"J. Consult. Clin. Psychol."},{"key":"ref_44","unstructured":"Frye, J.M. (2013). The Lived Experience of very Long-Term Cancer Survivors: Meaning-Making and Meanings Made. [Ph.D. Dissertation, Fielding Graduate University]. Publication Number: 3603531."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1002\/pon.1322","article-title":"Spirituality as a core domain in the assessment of quality of life in oncology","volume":"17","author":"Whitford","year":"2008","journal-title":"Psychooncology"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s10943-014-9827-1","article-title":"Qualitative investigation of the effects of psycho-spiritual integrative therapy on breast cancer survivors\u2019 experience of paradox","volume":"54","author":"Patel","year":"2015","journal-title":"J. Relig. Health"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1200\/JCO.2003.12.058","article-title":"Cancer patients seeking a second surgical opinion: Results of a study on motives, needs, and expectations","volume":"21","author":"Mellink","year":"2003","journal-title":"J. Clin. Oncol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/s11764-008-0055-0","article-title":"Health-related information needs in a large and diverse sample of adult cancer survivors: Implications for cancer care","volume":"2","author":"Beckjord","year":"2008","journal-title":"J. Cancer Surviv."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1111\/1467-8721.00124","article-title":"Psychoneuroimmunology","volume":"10","author":"Ader","year":"2001","journal-title":"Curr. Dir. Psychol. Sci."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1037\/0003-066X.59.1.29","article-title":"How the Mind Hurts and Heals the Body","volume":"59","author":"Ray","year":"2004","journal-title":"Am. Psychol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1097\/00006842-197507000-00007","article-title":"Behaviorally conditioned immunosuppression","volume":"37","author":"Ader","year":"1975","journal-title":"Psychosom. Med."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1097\/00012272-200510000-00004","article-title":"Implementing a comprehensive approach to the study of health dynamics using the psychoneuroimmunology paradigm","volume":"28","author":"McCain","year":"2005","journal-title":"Adv. Nurs. Sci."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1176\/ajp.155.4.457","article-title":"A New Intellectual Framework for Psychiatry","volume":"155","author":"Kandel","year":"1998","journal-title":"Am. J. Psychiatry"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0889-1591(03)00033-3","article-title":"Psychoneuroimmunology and health psychology: An integrative model","volume":"17","author":"Lutgendorf","year":"2003","journal-title":"Brain Behav. Immun."}],"container-title":["Journal of Personalized Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4426\/5\/2\/174\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T20:47:05Z","timestamp":1760215625000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4426\/5\/2\/174"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5,28]]},"references-count":54,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2015,6]]}},"alternative-id":["jpm5020174"],"URL":"https:\/\/doi.org\/10.3390\/jpm5020174","relation":{},"ISSN":["2075-4426"],"issn-type":[{"type":"electronic","value":"2075-4426"}],"subject":[],"published":{"date-parts":[[2015,5,28]]}}}