{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T21:18:29Z","timestamp":1773350309976,"version":"3.50.1"},"reference-count":14,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,1,9]],"date-time":"2022-01-09T00:00:00Z","timestamp":1641686400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Cerebral venous thrombosis accounts for 0.5\u20131% of all cerebrovascular events and is one type of stroke that affects the veins and cerebral sinuses. Females are more affected than males, as they may have risk factors, such as pregnancy, first period after pregnancy, treatment with oral contraceptives treatment with hormonal replacement, or hereditary thrombophilia. This neurological pathology may endanger a patient\u2019s life. However, it must be suspected in its acute phase, when it presents with variable clinical characteristics, so that special treatment can be initiated to achieve a favorable outcome with partial or complete functional recovery. The case study describes the data and the treatment of two patients with confirmed cerebral venous thrombosis with various localizations and associated risk factors, who were admitted to the neurology department of the Sf. Apostol Andrei Emergency Hospital in Constanta. The first patient was 40 years old and affected by sigmoid sinus and right lateral sinus thrombosis, inferior sagittal sinus, and right sinus thrombosis, associated with right temporal subacute cortical and subcortical hemorrhage, which appeared following a voluntary abortion. The second case was a patient aged 25 who was affected by left parietal cortical vein thrombosis, associated with ipsilateral superior parietal subcortical venous infarction, which appeared following labor. The data are strictly observational and offer a perspective on clinical manifestations and clinical and paraclinical investigations, including the treatment of young patients who had been diagnosed with cerebral venous thrombosis and admitted to the neurology department.<\/jats:p>","DOI":"10.3390\/life12010090","type":"journal-article","created":{"date-parts":[[2022,1,9]],"date-time":"2022-01-09T23:06:15Z","timestamp":1641769575000},"page":"90","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Case Reports of Pregnancy-Related Cerebral Venous Thrombosis in the Neurology Department of the Emergency Clinical Hospital in Constanta"],"prefix":"10.3390","volume":"12","author":[{"given":"Any Docu","family":"Axelerad","sequence":"first","affiliation":[{"name":"Department of Neurology, General Medicine Faculty, Ovidius University, 900470 Constanta, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lavinia Alexandra","family":"Zlotea","sequence":"additional","affiliation":[{"name":"Radiology-Medical Imaging, Sf Apostol Andrei Emergency County Clinical Hospital, 900591 Constanta, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen Adella","family":"Sirbu","sequence":"additional","affiliation":[{"name":"Department of Neurology, Titu Maiorescu University, 040441 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alina Zorina","family":"Stroe","sequence":"additional","affiliation":[{"name":"Department of Neurology, General Medicine Faculty, Ovidius University, 900470 Constanta, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silviu Docu","family":"Axelerad","sequence":"additional","affiliation":[{"name":"Faculty of General Medicine, \u2018Vasile Goldis\u2019 University, 317046 Arad, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simona Claudia","family":"Cambrea","sequence":"additional","affiliation":[{"name":"Infectious Diseases Clinic, Clinical Infectious Diseases Hospital, 900708 Constanta, Romania"},{"name":"Department of Infectious Diseases, General Medicine Faculty, Ovidius University, 900470 Constanta, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lavinia Florenta","family":"Muja","sequence":"additional","affiliation":[{"name":"Department of Neurology, General Medicine Faculty, Ovidius University, 900470 Constanta, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,1,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"43866","DOI":"10.1038\/srep43866","article-title":"Clinical characteristics and prognosis of cerebral venous thrombosis in Chinese women during pregnancy and puerperium","volume":"7","author":"Liang","year":"2017","journal-title":"Sci. Rep."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S1474-4422(07)70029-7","article-title":"Cerebral venous thrombosis: An update","volume":"6","author":"Bousser","year":"2007","journal-title":"Lancet Neurol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.9734\/JAMMR\/2018\/38540","article-title":"In-hospital imaging prevalence, patterns of neurological involvement in cerebral venous sinus thrombosis: Analysis from Pakistan","volume":"25","author":"Mubarak","year":"2018","journal-title":"J. Adv. Med. Med. Res."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Bano, S., Farooq, M.U., Nazir, S., Aslam, A., Tariq, A., Javed, M.A., Rehman, H., and Numan, A. (2021). Structural imaging characteristic, clinical features and risk factors of cerebral venous sinus thrombosis: A prospective cross-sectional analysis from a tertiary care hospital in Pakistan. 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Legeforening, 138."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1161\/01.STR.24.12.1880","article-title":"Cerebral venous thrombosis associated with pregnancy and puerperium","volume":"24","author":"Barinagarrementeria","year":"1993","journal-title":"Stroke"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"2312","DOI":"10.1016\/j.jstrokecerebrovasdis.2016.05.025","article-title":"Cerebral venous thrombosis associated with intracranial hemorrhage and timing of anticoagulation after hemicraniectomy","volume":"25","author":"Pizzi","year":"2016","journal-title":"J. Stroke Cerebrovasc. Dis."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1161\/CIRCULATIONAHA.111.067835","article-title":"Cerebral Venous Thrombosis","volume":"125","author":"Piazza","year":"2012","journal-title":"Circulation"}],"container-title":["Life"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-1729\/12\/1\/90\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T14:01:48Z","timestamp":1760364108000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-1729\/12\/1\/90"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,9]]},"references-count":14,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,1]]}},"alternative-id":["life12010090"],"URL":"https:\/\/doi.org\/10.3390\/life12010090","relation":{},"ISSN":["2075-1729"],"issn-type":[{"value":"2075-1729","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,9]]}}}