{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T06:46:47Z","timestamp":1774680407893,"version":"3.50.1"},"reference-count":20,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2022,6,16]],"date-time":"2022-06-16T00:00:00Z","timestamp":1655337600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Research, Development and Innovation Fund of Hungary","award":["NVKP_16-1\u20132016-0017"],"award-info":[{"award-number":["NVKP_16-1\u20132016-0017"]}]},{"name":"National Research, Development and Innovation Fund of Hungary","award":["2020-4.1.1.-TKP2020"],"award-info":[{"award-number":["2020-4.1.1.-TKP2020"]}]},{"name":"National Research, Development and Innovation Fund of Hungary","award":["EFOP-3.6.3-VEKOP-16-2017-00009"],"award-info":[{"award-number":["EFOP-3.6.3-VEKOP-16-2017-00009"]}]},{"name":"Ministry for Innovation and Technology in Hungary","award":["NVKP_16-1\u20132016-0017"],"award-info":[{"award-number":["NVKP_16-1\u20132016-0017"]}]},{"name":"Ministry for Innovation and Technology in Hungary","award":["2020-4.1.1.-TKP2020"],"award-info":[{"award-number":["2020-4.1.1.-TKP2020"]}]},{"name":"Ministry for Innovation and Technology in Hungary","award":["EFOP-3.6.3-VEKOP-16-2017-00009"],"award-info":[{"award-number":["EFOP-3.6.3-VEKOP-16-2017-00009"]}]},{"name":"Semmelweis University","award":["NVKP_16-1\u20132016-0017"],"award-info":[{"award-number":["NVKP_16-1\u20132016-0017"]}]},{"name":"Semmelweis University","award":["2020-4.1.1.-TKP2020"],"award-info":[{"award-number":["2020-4.1.1.-TKP2020"]}]},{"name":"Semmelweis University","award":["EFOP-3.6.3-VEKOP-16-2017-00009"],"award-info":[{"award-number":["EFOP-3.6.3-VEKOP-16-2017-00009"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Our purpose was to evaluate the risk associated with the learning curve of starting a complex aortic programme in an Eastern European country. A retrospective study was conducted involving the initial 20 patients (16 males, mean age: 65 \u00b1 11 years) undergoing fenestrated\/branched endovascular aortic repair in a single centre. Demographic, anatomical, procedural, and postoperative variables were collected. Our elective patient cohort consisted of 9 pararenal aneurysms (45%) and 11 thoracoabdominal aortic aneurysms (55%), with the latter including 4 chronic dissection cases (20%). A total of 71 branch vessels were incorporated (3.5 \u00b1 0.9 per patient). The per vessel technical success rate was 100%. In-hospital mortality was 5% (1\/20). At an average follow-up of 14 \u00b1 22 months, the primary clinical success rate was 45% (9\/20) and the secondary clinical success was achieved in 75% of cases (15\/20). All-cause mortality at 14 months was 20% (4\/20; aortic related: 1\/20, 5%). Four bridging stent occlusions were found (5.6%). Mortality and reintervention rates were comparable to the initial results of high-volume centres, while the complexity of our cases and the per vessel technical success rate was comparable to the values reported as late experience. The morbidity of the learning curve could be decreased if operators are skilled in basic endovascular procedures.<\/jats:p>","DOI":"10.3390\/life12060902","type":"journal-article","created":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T05:25:11Z","timestamp":1655443511000},"page":"902","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Complex Aortic Interventions Can Be Safely Introduced to the Clinical Practice by Physicians Skilled in Basic Endovascular Techniques"],"prefix":"10.3390","volume":"12","author":[{"given":"Sarolta","family":"Borzs\u00e1k","sequence":"first","affiliation":[{"name":"Department of Interventional Radiology, Semmelweis University, 1122 Budapest, Hungary"},{"name":"Semmelweis Aortic Center, Heart and Vascular Center, Semmelweis University, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e1s","family":"Szentiv\u00e1nyi","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, Semmelweis University, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e1s","family":"S\u00fcvegh","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, Semmelweis University, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele Mariastefano","family":"Fontanini","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, Semmelweis University, 1122 Budapest, Hungary"},{"name":"Semmelweis Aortic Center, Heart and Vascular Center, Semmelweis University, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mil\u00e1n","family":"Vecsey-Nagy","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, Semmelweis University, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P\u00e9ter","family":"Banga","sequence":"additional","affiliation":[{"name":"Semmelweis Aortic Center, Heart and Vascular Center, Semmelweis University, 1122 Budapest, Hungary"},{"name":"Department of Vascular and Endovascular Surgery, Semmelweis University, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zolt\u00e1n","family":"Szeberin","sequence":"additional","affiliation":[{"name":"Semmelweis Aortic Center, Heart and Vascular Center, Semmelweis University, 1122 Budapest, Hungary"},{"name":"Department of Vascular and Endovascular Surgery, Semmelweis University, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P\u00e9ter","family":"S\u00f3tonyi","sequence":"additional","affiliation":[{"name":"Semmelweis Aortic Center, Heart and Vascular Center, Semmelweis University, 1122 Budapest, Hungary"},{"name":"Department of Vascular and Endovascular Surgery, Semmelweis University, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0826-7888","authenticated-orcid":false,"given":"Csaba","family":"Csobay-Nov\u00e1k","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, Semmelweis University, 1122 Budapest, Hungary"},{"name":"Semmelweis Aortic Center, Heart and Vascular Center, Semmelweis University, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.ejvs.2019.11.030","article-title":"Editor\u2019s Choice\u2014Endovascular vs. Open Repair for Abdominal Aortic Aneurysm: Systematic Review and Meta-analysis of Updated Peri-operative and Long Term Data of Randomised Controlled Trials","volume":"59","author":"Antoniou","year":"2020","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.avsg.2020.12.047","article-title":"Perioperative Outcome of Fenestrated and Branched Stent Grafting after Previous Open or Endovascular Abdominal Aortic Repair","volume":"74","author":"Makaloski","year":"2021","journal-title":"Ann. Vasc. Surg."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1177\/152660280100800102","article-title":"Endoluminal aortic grafting with renal and superior mesenteric artery incorporation by graft fenestration","volume":"8","author":"Anderson","year":"2001","journal-title":"J. Endovasc."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ejvs.2018.09.020","article-title":"Editor\u2019s Choice\u2014European Society for Vascular Surgery (ESVS) 2019 Clinical Practice Guidelines on the Management of Abdominal Aorto-iliac Artery Aneurysms","volume":"57","author":"Wanhainen","year":"2019","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1948","DOI":"10.1161\/CIRCULATIONAHA.116.024870","article-title":"Variations in Abdominal Aortic Aneurysm Care: A Report From the International Consortium of Vascular Registries","volume":"134","author":"Beck","year":"2016","journal-title":"Circulation"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1016\/j.jvs.2020.07.100","article-title":"Evolution of fenestrated\/branched endovascular aortic aneurysm repair complexity and outcomes at an organized center for the treatment of complex aortic disease","volume":"73","author":"Simons","year":"2021","journal-title":"J. Vasc. Surg."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"4S","DOI":"10.1016\/j.jvs.2020.06.011","article-title":"Reporting standards for endovascular aortic repair of aneurysms involving the renal-mesenteric arteries","volume":"73","author":"Oderich","year":"2021","journal-title":"J. Vasc. Surg."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1097\/SLA.0000000000002960","article-title":"Analysis of the Learning Curve and Patient Outcomes of Endovascular Repair of Thoracoabdominal Aortic Aneurysms Using Fenestrated and Branched Stent Grafts: Prospective, Nonrandomized, Single-center Physician-sponsored Investigational Device Exemption Clinical Study","volume":"268","author":"Schneider","year":"2018","journal-title":"Ann. Surg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1016\/j.jvs.2016.10.101","article-title":"Trends in use of the only Food and Drug Administration-approved commercially available fenestrated endovascular aneurysm repair device in the United States","volume":"65","author":"Simons","year":"2017","journal-title":"J. Vasc. Surg."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.jvs.2016.12.111","article-title":"Outcomes of fenestrated and branched endovascular repair of complex abdominal and thoracoabdominal aortic aneurysms","volume":"66","author":"Schanzer","year":"2017","journal-title":"J. Vasc. Surg."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1556\/650.2021.32118","article-title":"Analysis of data from the National Vascular Registry on infrarenal aortic aneurysms (2010\u20132019)","volume":"162","author":"Hidi","year":"2021","journal-title":"Orv. Hetil."},{"key":"ref_12","first-page":"1492","article-title":"Association of Hospital Volume with Perioperative Mortality of Endovascular Repair of Complex Aortic Aneurysms: A Nationwide Cohort Study","volume":"75","author":"Alberga","year":"2022","journal-title":"Ann. Surg."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.jvs.2019.09.046","article-title":"Learning curve of fenestrated and branched endovascular aortic repair for pararenal and thoracoabdominal aneurysms","volume":"72","author":"Mirza","year":"2020","journal-title":"J. Vasc. Surg."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1016\/j.jtcvs.2015.12.050","article-title":"Outcomes of 3309 thoracoabdominal aortic aneurysm repairs","volume":"151","author":"Coselli","year":"2016","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1097\/SLA.0000000000000612","article-title":"Results and factors affecting early outcome of fenestrated and\/or branched stent grafts for aortic aneurysms: A multicenter prospective study","volume":"261","author":"Marzelle","year":"2015","journal-title":"Ann. Surg."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.jvs.2014.09.011","article-title":"Staged endovascular repair of thoracoabdominal aortic aneurysms limits incidence and severity of spinal cord ischemia","volume":"61","author":"Mastracci","year":"2015","journal-title":"J. Vasc. Surg."},{"key":"ref_17","first-page":"261","article-title":"Learning curve in fenestrated and branched grafting","volume":"58","author":"Mastracci","year":"2017","journal-title":"J. Cardiovasc. Surg."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s00270-001-0074-y","article-title":"Angioplasty of the innominate artery in 89 patients: Experience over 19 years","volume":"25","author":"Nemes","year":"2002","journal-title":"Cardiovasc. Interv. Radiol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1177\/1708538118799132","article-title":"Assessing the institutional learning curve for pararenal aortic repair using the fenestrated Anaconda endograft","volume":"27","author":"Taher","year":"2019","journal-title":"Vascular"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1097\/SLA.0000000000004982","article-title":"Midterm Outcomes of a Prospective, Nonrandomized Study to Evaluate Endovascular Repair of Complex Aortic Aneurysms Using Fenestrated-Branched Endografts","volume":"274","author":"Oderich","year":"2021","journal-title":"Ann. 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