{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T06:24:25Z","timestamp":1789453465813,"version":"build-2803163510"},"reference-count":69,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2022,9,18]],"date-time":"2022-09-18T00:00:00Z","timestamp":1663459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Background: An arteriovenous fistula (AVF) is the first-line vascular access pathway for patients diagnosed with end-stage renal disease (ESRD). In planning vascular access, it is necessary to check the diameters of the venous and arterial components for satisfactory long-term results. Furthermore, the mechanism underlying the maturation failure and short-term patency in cases of AVFs is not fully known. This study aims to verify the predictive role of inflammatory biomarkers (the neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), systemic inflammatory index (SII), and C-reactive protein (CRP)), Ca-P product, the prognostic nutritional index (PNI), and the diameters of the venous and arterial components in the failure of AVF maturation. Methods: The present study was designed as an observational, analytical, and retrospective cohort study with a longitudinal follow-up, and included all patients with a diagnosis of ESRD that were admitted to the Vascular Surgery Clinic of the Targu Mures Emergency County Hospital, Romania, between January 2019 and December 2021. Results: The maturation of AVF at 6 weeks was clearly lower in cases of patients in the high-NLR (31.88% vs. 91.36%; p &lt; 0.0001), high-PLR (46.94% vs. 85.55%; p &lt; 0.0001), high-SII (44.28% vs. 88.89%; p &lt; 0.0001), high-CRP (46.30% vs. 88.73%; p &lt; 0.0001), high-Ca-P product (40.43% vs. 88.46%; p &lt; 0.0001), and low-PNI (34.78% vs. 91.14%; p &lt; 0.0001) groups, as well as in patients with a lower radial artery (RA) diameter (40% vs. 94.87%; p = 0.0009), cephalic vein (CV) diameter (44.82% vs. 97.14%; p = 0.0001) for a radio-cephalic AVF (RC-AVF), and brachial artery (BA) diameter (30.43% vs. 89.47%; p &lt; 0.0001) in addition to CV diameter (40% vs. 94.59%; p &lt; 0.0001) for a brachio-cephalic AVF (BC-AVF), respectively. There was also a significant increase in early thrombosis and short-time mortality in the same patients. A multivariate analysis showed that a baseline value for the NLR, PLR, SII, CRP, Ca-P product, and PNI was an independent predictor of adverse outcomes for all of the recruited patients. Furthermore, for all patients, a high baseline value for vessel diameter was a protective factor against any negative events during the study period, except for RA diameter in mortality (p = 0.16). Conclusion: Our findings concluded that higher NLR, PLR, SII, CRP, Ca-P product, and PNI values determined preoperatively were strongly predictive of AVF maturation failure, early thrombosis, and short-time mortality. Moreover, a lower baseline value for vessel diameter was strongly predictive of AVF maturation failure and early thrombosis.<\/jats:p>","DOI":"10.3390\/life12091447","type":"journal-article","created":{"date-parts":[[2022,9,19]],"date-time":"2022-09-19T02:06:50Z","timestamp":1663553210000},"page":"1447","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["The Predictive Value of Systemic Inflammatory Markers, the Prognostic Nutritional Index, and Measured Vessels\u2019 Diameters in Arteriovenous Fistula Maturation Failure"],"prefix":"10.3390","volume":"12","author":[{"given":"R\u00e9ka","family":"Kaller","sequence":"first","affiliation":[{"name":"Clinic of Vascular Surgery, Mure\u0219 County Emergency Hospital, 540136 T\u00e2rgu-Mure\u0219, Romania"},{"name":"Doctoral School of Medicine and Pharmacy, University of Medicine, Pharmacy, Science and Technology \u201cGeorge Emil Palade\u201d of T\u00e2rgu-Mure\u0219, 540139 T\u00e2rgu-Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1664-8130","authenticated-orcid":false,"given":"Emil Marian","family":"Arb\u0103na\u0219i","sequence":"additional","affiliation":[{"name":"Clinic of Vascular Surgery, Mure\u0219 County Emergency Hospital, 540136 T\u00e2rgu-Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian Vasile","family":"Mure\u0219an","sequence":"additional","affiliation":[{"name":"Clinic of Vascular Surgery, Mure\u0219 County Emergency Hospital, 540136 T\u00e2rgu-Mure\u0219, Romania"},{"name":"Department of Surgery, University of Medicine, Pharmacy, Science and Technology \u201cGeorge Emil Palade\u201d of T\u00e2rgu-Mure\u0219, 540139 T\u00e2rgu-Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Septimiu","family":"Void\u0103zan","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, University of Medicine, Pharmacy, Science and Technology \u201cGeorge Emil Palade\u201d of T\u00e2rgu-Mure\u0219, 540139 T\u00e2rgu-Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliza Mihaela","family":"Arb\u0103na\u0219i","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy, University of Medicine, Pharmacy, Science and Technology \u201cGeorge Emil Palade\u201d of T\u00e2rgu-Mure\u0219, 540139 T\u00e2rgu-Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Em\u0151ke","family":"Horv\u00e1th","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Medicine, Pharmacy, Science and Technology \u201cGeorge Emil Palade\u201d of T\u00e2rgu-Mure\u0219, 540142 T\u00e2rgu-Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bogdan Andrei","family":"Suciu","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Medicine, Pharmacy, Science and Technology \u201cGeorge Emil Palade\u201d of T\u00e2rgu-Mure\u0219, 540139 T\u00e2rgu-Mure\u0219, Romania"},{"name":"Department of Anatomy, University of Medicine, Pharmacy, Science and Technology \u201cGeorge Emil Palade\u201d of T\u00e2rgu-Mure\u0219, 540142 T\u00e2rgu-Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioan","family":"Hosu","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Mures County Emergency Hospital, 540136 T\u00e2rgu-Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioana","family":"Halmaciu","sequence":"additional","affiliation":[{"name":"Department of Anatomy, University of Medicine, Pharmacy, Science and Technology \u201cGeorge Emil Palade\u201d of T\u00e2rgu-Mure\u0219, 540142 T\u00e2rgu-Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klara","family":"Brinzaniuc","sequence":"additional","affiliation":[{"name":"Department of Anatomy, University of Medicine, Pharmacy, Science and Technology \u201cGeorge Emil Palade\u201d of T\u00e2rgu-Mure\u0219, 540142 T\u00e2rgu-Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliza","family":"Russu","sequence":"additional","affiliation":[{"name":"Clinic of Vascular Surgery, Mure\u0219 County Emergency Hospital, 540136 T\u00e2rgu-Mure\u0219, Romania"},{"name":"Department of Surgery, University of Medicine, Pharmacy, Science and Technology \u201cGeorge Emil Palade\u201d of T\u00e2rgu-Mure\u0219, 540139 T\u00e2rgu-Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"34S","DOI":"10.1016\/j.jvs.2008.08.044","article-title":"Autogenous versus Prosthetic Vascular Access for Hemodialysis: A Systematic Review and Meta-Analysis","volume":"48","author":"Murad","year":"2008","journal-title":"J. Vasc. Surg."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.jvs.2016.01.053","article-title":"Outcomes of Vascular Access for Hemodialysis: A Systematic Review and Meta-Analysis","volume":"64","author":"Almasri","year":"2016","journal-title":"J. Vasc. Surg."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1681\/ASN.2016040412","article-title":"Complications of the Arteriovenous Fistula: A Systematic Review","volume":"28","author":"Liu","year":"2017","journal-title":"J. Am. Soc. Nephrol. JASN"},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Kaller, R., Mure\u0219an, A.V., Arb\u0103na\u0219i, E.M., Arb\u0103na\u0219i, E.M., Kov\u00e1cs, I., Horv\u00e1th, E., Suciu, B.A., Hosu, I., and Russu, E. (2022). Uncommon Surgical Management by AVF between the Great Saphenous Vein and Anterior Tibial Artery for Old Radiocephalic AVF Failure. Life, 12.","DOI":"10.3390\/life12040529"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.37358\/MP.22.2.5579","article-title":"Polytetrafluorethylene Prosthesis Interposition in Vascular Access","volume":"59","author":"Russu","year":"2022","journal-title":"Mater. Plast."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.ejvs.2018.02.001","article-title":"Editor\u2019s Choice\u2014Vascular Access: 2018 Clinical Practice Guidelines of the European Society for Vascular Surgery (ESVS)","volume":"55","author":"Schmidli","year":"2018","journal-title":"Eur. J. Vasc. Endovasc. Surg. Off. J. Eur. Soc. Vasc. Surg."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"S66","DOI":"10.1053\/ajkd.2001.20748","article-title":"National Kidney Foundation K\/DOQI Clinical Practice Guidelines for Nutrition in Chronic Renal Failure","volume":"37","author":"Kopple","year":"2001","journal-title":"Am. J. Kidney Dis."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1053\/j.ajkd.2019.12.001","article-title":"KDOQI Clinical Practice Guideline for Vascular Access: 2019 Update","volume":"75","author":"Lok","year":"2020","journal-title":"Am. J. Kidney Dis."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1053\/j.ajkd.2017.11.020","article-title":"Arteriovenous Fistula Maturation in Prevalent Hemodialysis Patients in the United States: A National Study","volume":"71","author":"Woodside","year":"2018","journal-title":"Am. J. Kidney Dis. Off. J. Natl. Kidney Found."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"2735","DOI":"10.1681\/ASN.2017111225","article-title":"Prediction of Arteriovenous Fistula Clinical Maturation from Postoperative Ultrasound Measurements: Findings from the Hemodialysis Fistula Maturation Study","volume":"29","author":"Robbin","year":"2018","journal-title":"J. Am. Soc. Nephrol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1097\/01.ASN.0000103870.31606.90","article-title":"Cardiovascular Comorbidity and Late Referral Impact Arteriovenous Fistula Survival: A Prospective Multicenter Study","volume":"15","author":"Ravani","year":"2004","journal-title":"J. Am. Soc. Nephrol. JASN"},{"key":"ref_12","first-page":"ii88","article-title":"EBPG on Vascular Access","volume":"22","author":"Tordoir","year":"2007","journal-title":"Nephrol. Dial. Transplant. Off. Publ. Eur. Dial. Transpl. Assoc. -Eur. Ren. Assoc."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1053\/ajkd.2000.8241","article-title":"Timing of Nephrology Referral: Influence on Mortality and Morbidity","volume":"36","author":"Roubicek","year":"2000","journal-title":"Am. J. Kidney Dis. Off. J. Natl. Kidney Found."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/S0895-4356(02)00415-8","article-title":"Delayed Nephrologist Referral and Inadequate Vascular Access in Patients with Advanced Chronic Kidney Failure","volume":"55","author":"Avorn","year":"2002","journal-title":"J. Clin. Epidemiol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.3109\/0886022X.2013.815100","article-title":"The Relationship between Arteriovenous Fistula Success and Inflammation","volume":"35","author":"Kaygin","year":"2013","journal-title":"Ren. Fail."},{"key":"ref_16","first-page":"157","article-title":"Association between Raised Serum C-Reactive Protein and Arteriovenous Fistula Failure","volume":"5","author":"Usman","year":"2016","journal-title":"J. Islamabad Med. Dent. Coll."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1177\/1129729819826037","article-title":"Role of Neutrophil-to-Lymphocyte Ratio as a Prognostic Indicator for Hemodialysis Arteriovenous Fistula Failure","volume":"20","author":"Wongmahisorn","year":"2019","journal-title":"J. Vasc. Access"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1177\/1129729819894113","article-title":"Relationship of Arteriovenous Fistula Stenosis and Thrombosis with the Platelet\u2013Lymphocyte Ratio in Hemodialysis Patients","volume":"21","author":"Sarioglu","year":"2020","journal-title":"J. Vasc. Access"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.jvs.2018.10.100","article-title":"C-Reactive Protein as a Prognostic Risk Factor for Loss of Arteriovenous Fistula Patency in Hemodialyzed Patients","volume":"70","author":"Stirbu","year":"2019","journal-title":"J. Vasc. Surg."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Arb\u0103na\u0219i, E.M., Mure\u0219an, A.V., Co\u0219arc\u0103, C.M., Kaller, R., Bud, T.I., Hosu, I., Void\u0103zan, S.T., Arb\u0103na\u0219i, E.M., and Russu, E. (2022). Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio Impact on Predicting Outcomes in Patients with Acute Limb Ischemia. Life, 12.","DOI":"10.3390\/life12060822"},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Taurino, M., Aloisi, F., Del Porto, F., Nespola, M., Dezi, T., Pranteda, C., Rizzo, L., and Sirignano, P. (2021). Neutrophil-to-Lymphocyte Ratio Could Predict Outcome in Patients Presenting with Acute Limb Ischemia. J. Clin. Med., 10.","DOI":"10.3390\/jcm10194343"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1177\/1538574413519713","article-title":"Neutrophil to Lymphocyte Ratio Predicts Perioperative Mortality Following Open Elective Repair of Abdominal Aortic Aneurysms","volume":"48","author":"Appleton","year":"2014","journal-title":"Vasc. Endovasc. Surg."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Ntalouka, M.P., Nana, P., Kouvelos, G.N., Stamoulis, K., Spanos, K., Giannoukas, A., Matsagkas, M., and Arnaoutoglou, E. (2021). Association of Neutrophil\u2013Lymphocyte and Platelet\u2013Lymphocyte Ratio with Adverse Events in Endovascular Repair for Abdominal Aortic Aneurysm. J. Clin. Med., 10.","DOI":"10.3390\/jcm10051083"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.avsg.2018.01.059","article-title":"Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio Are Effective Predictors of Prognosis in Patients with Acute Mesenteric Arterial Embolism and Thrombosis","volume":"49","author":"Wang","year":"2018","journal-title":"Ann. Vasc. Surg."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.avsg.2012.12.009","article-title":"Usefulness of Neutrophil\/Lymphocyte Ratio as a Predictor of Amputation after Embolectomy for Acute Limb Ischemia","volume":"28","author":"Sert","year":"2014","journal-title":"Ann. Vasc. Surg."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1177\/1538574418789046","article-title":"Association of Platelet to Lymphocyte Ratio and Risk of 30-Day Postoperative Complications in Patients Undergoing Abdominal Aortic Surgical Repair","volume":"53","author":"Lareyre","year":"2019","journal-title":"Vasc. Endovasc. Surg."},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Drugescu, A., Roca, M., Zota, I.M., Costache, A.-D., Gavril, O.I., Gavril, R.S., Vasilcu, T.F., Mitu, O., Esanu, I.M., and Roca, I.-C. (2022). Value of the Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio in Predicting CPET Performance in Patients with Stable CAD and Recent Elective PCI. Med. Kaunas Lith., 58.","DOI":"10.3390\/medicina58060814"},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Russu, E., Mure\u0219an, A.V., Arb\u0103na\u0219i, E.M., Kaller, R., Hosu, I., Void\u0103zan, S., Arb\u0103na\u0219i, E.M., and Co\u0219arc\u0103, C.M. (2022). The Predictive Role of NLR and PLR in Outcome and Patency of Lower Limb Revascularization in Patients with Femoropopliteal Disease. J. Clin. Med., 11.","DOI":"10.3390\/jcm11092620"},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Mure\u0219an, A.V., Russu, E., Arb\u0103na\u0219i, E.M., Kaller, R., Hosu, I., Arb\u0103na\u0219i, E.M., and Void\u0103zan, S.T. (2022). The Predictive Value of NLR, MLR, and PLR in the Outcome of End-Stage Kidney Disease Patients. Biomedicines, 10.","DOI":"10.3390\/biomedicines10061272"},{"key":"ref_30","first-page":"55","article-title":"Neutrophil-to-Lymphocyte Ratio Predicts Long-Term All-Cause Mortality in Patients with Chronic Kidney Disease Stage 5","volume":"59","author":"Woziwodzka","year":"2019","journal-title":"Folia Med. Cracov."},{"key":"ref_31","first-page":"132","article-title":"Neutrophil\/Lymphocyte Ratio: A Promising Prognostic Marker in Patients with Chronic Kidney Disease","volume":"2","author":"Kato","year":"2015","journal-title":"Inflamm. Cell Signal."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s11255-018-1994-7","article-title":"Does Neutrophyl to Lymphocyte Ratio Really Predict Chronic Kidney Disease Progression?","volume":"51","author":"Altunoren","year":"2019","journal-title":"Int. Urol. Nephrol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1007\/s10157-012-0728-x","article-title":"Neutrophil to Lymphocyte Ratio Independently Predicts Cardiovascular Events in Patients with Chronic Kidney Disease","volume":"17","author":"Solak","year":"2013","journal-title":"Clin. Exp. Nephrol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"e13340","DOI":"10.1097\/MD.0000000000013340","article-title":"Preoperative Elevated Neutrophil-to-Lymphocyte Ratio (NLR) and Derived NLR Are Associated with Poor Prognosis in Patients with Breast Cancer","volume":"97","author":"Duan","year":"2018","journal-title":"Medicine"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"6261","DOI":"10.3748\/wjg.v23.i34.6261","article-title":"Systemic Immune-Inflammation Index for Predicting Prognosis of Colorectal Cancer","volume":"23","author":"Chen","year":"2017","journal-title":"World J. Gastroenterol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"4392189","DOI":"10.1155\/2020\/4392189","article-title":"Prognostic Value of Pretreatment Systemic Immune-Inflammation Index in Glioblastoma Multiforme Patients Undergoing Postneurosurgical Radiotherapy Plus Concurrent and Adjuvant Temozolomide","volume":"2020","author":"Topkan","year":"2020","journal-title":"Mediat. Inflamm."},{"key":"ref_37","first-page":"1001","article-title":"Prognostic nutritional index in gastrointestinal surgery of malnourished cancer patients","volume":"85","author":"Onodera","year":"1984","journal-title":"Nihon Geka Gakkai Zasshi"},{"key":"ref_38","doi-asserted-by":"crossref","unstructured":"Zhang, J., Xiao, X., Wu, Y., Yang, J., Zou, Y., Zhao, Y., Yang, Q., and Liu, F. (2022). Prognostic Nutritional Index as a Predictor of Diabetic Nephropathy Progression. Nutrients, 14.","DOI":"10.3390\/nu14173634"},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Lin, T.-Y., and Hung, S.-C. (2019). Geriatric Nutritional Risk Index Is Associated with Unique Health Conditions and Clinical Outcomes in Chronic Kidney Disease Patients. Nutrients, 11.","DOI":"10.3390\/nu11112769"},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Ruperto, M., and Barril, G. (2022). Nutritional Status, Body Composition, and Inflammation Profile in Older Patients with Advanced Chronic Kidney Disease Stage 4\u20135: A Case-Control Study. Nutrients, 14.","DOI":"10.3390\/nu14173650"},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Sim, J.H., Jun, I.-G., Moon, Y.-J., Jeon, A.R., Kim, S.-H., Kim, B., and Song, J.-G. (2021). Association of Preoperative Prognostic Nutritional Index and Postoperative Acute Kidney Injury in Patients Who Underwent Hepatectomy for Hepatocellular Carcinoma. J. Pers. Med., 11.","DOI":"10.3390\/jpm11050428"},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Sim, J.-H., Bang, J.-Y., Kim, S.-H., Kang, S.-J., and Song, J.-G. (2021). Association of Preoperative Prognostic Nutritional Index and Postoperative Acute Kidney Injury in Patients with Colorectal Cancer Surgery. Nutrients, 13.","DOI":"10.3390\/nu13051604"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1053\/j.ackd.2009.06.009","article-title":"Advances and New Frontiers in the Pathophysiology of Venous Neointimal Hyperplasia and Dialysis Access Stenosis","volume":"16","author":"Lee","year":"2009","journal-title":"Adv. Chronic Kidney Dis."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.kint.2015.12.019","article-title":"The Molecular Mechanisms of Hemodialysis Vascular Access Failure","volume":"89","author":"Brahmbhatt","year":"2016","journal-title":"Kidney Int."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1053\/j.semvascsurg.2016.08.005","article-title":"Future Research Directions to Improve Fistula Maturation and Reduce Access Failure","volume":"29","author":"Hu","year":"2016","journal-title":"Semin. Vasc. Surg."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"199","DOI":"10.5414\/CN108584","article-title":"Neutrophil-to-Lymphocyte Ratio and Platelet-Tolymphocyte Ratio in Evaluation of Inflammation in End-Stage Renal Disease","volume":"85","author":"Ahbap","year":"2016","journal-title":"Clin. Nephrol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1111\/hdi.12040","article-title":"Platelet-to-Lymphocyte Ratio Better Predicts Inflammation than Neutrophil-to-Lymphocyte Ratio in End-Stage Renal Disease Patients","volume":"17","author":"Turkmen","year":"2013","journal-title":"Hemodial. Int."},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"Li, P., Xia, C., Liu, P., Peng, Z., Huang, H., Wu, J., and He, Z. (2020). Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Evaluation of Inflammation in Non-Dialysis Patients with End-Stage Renal Disease (ESRD). BMC Nephrol., 21.","DOI":"10.1186\/s12882-020-02174-0"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1007\/s11255-016-1301-4","article-title":"Platelet-to-Lymphocyte Ratio Predicts Mortality Better than Neutrophil-to-Lymphocyte Ratio in Hemodialysis Patients","volume":"48","author":"Yaprak","year":"2016","journal-title":"Int. Urol. Nephrol."},{"key":"ref_50","doi-asserted-by":"crossref","unstructured":"Zhu, F., Yao, Y., Ci, H., and Shawuti, A. (2021). Predictive Value of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio for Primary Patency of Percutaneous Transluminal Angioplasty in Hemodialysis Arteriovenous Fistula Stenosis. Vascular, 17085381211039672.","DOI":"10.1177\/17085381211039672"},{"key":"ref_51","doi-asserted-by":"crossref","unstructured":"Umeres-Francia1, G., Rojas-Fern\u00e1ndez, M., A\u00f1azco, P.H., and Benites-Zapata, V. (2021). Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio as a Risk Factor for Mortality in Peruvian Adults with Chronic Kidney Disease. Ren. Replace. Ther., 8, 30.","DOI":"10.1186\/s41100-022-00420-9"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"107413","DOI":"10.1016\/j.intimp.2021.107413","article-title":"Association of Platelet-to-Lymphocyte Ratio with Kidney Clinicopathologic Features and Renal Outcomes in Patients with Diabetic Kidney Disease","volume":"93","author":"Duan","year":"2021","journal-title":"Int. Immunopharmacol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"e6678960","DOI":"10.1155\/2021\/6678960","article-title":"Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Nondialysis Chronic Kidney Patients","volume":"2021","author":"Brito","year":"2021","journal-title":"Int. J. Inflamm."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1159\/000484177","article-title":"Lymphocyte Cell Ratios and Mortality among Incident Hemodialysis Patients","volume":"46","author":"Catabay","year":"2017","journal-title":"Am. J. Nephrol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1080\/0886022X.2019.1595645","article-title":"High Neutrophil\/Lymphocyte Ratio Is Associated with Poor Renal Outcomes in Japanese Patients with Chronic Kidney Disease","volume":"41","author":"Yoshitomi","year":"2019","journal-title":"Ren. Fail."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"70","DOI":"10.3109\/0886022X.2015.1104990","article-title":"Neutrophil\u2013Lymphocyte Ratio Predicts Cardiovascular and All-Cause Mortality in Hemodialysis Patients","volume":"38","author":"Neuen","year":"2016","journal-title":"Ren. Fail."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1159\/000488696","article-title":"High Neutrophil-to-Lymphocyte Ratio Is a Significant Predictor of Cardiovascular and All-Cause Mortality in Patients Undergoing Peritoneal Dialysis","volume":"43","author":"Lu","year":"2018","journal-title":"Kidney Blood Press. Res."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1159\/000510552","article-title":"Neutrophil to Lymphocyte Ratio as a Predictor of Long-Term Outcome in Peritoneal Dialysis Patients: A 5-Year Cohort Study","volume":"50","author":"Zhang","year":"2021","journal-title":"Blood Purif."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"129","DOI":"10.5835\/jecm.omu.30.02.008","article-title":"Neutrophil to Lymphocyte Ratio in Predicting Short-Term Mortality in Hemodialysis Patients","volume":"30","author":"Erdem","year":"2013","journal-title":"J. Exp. Clin. Med."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1007\/s11255-012-0130-3","article-title":"Elevated Neutrophil to Lymphocyte Ratio Predicts Overall and Cardiovascular Mortality in Maintenance Peritoneal Dialysis Patients","volume":"44","author":"An","year":"2012","journal-title":"Int. Urol. Nephrol."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.3892\/etm.2020.8756","article-title":"Neutrophil-to-lymphocyte Ratio and Red Blood Cell Distribution Width-to-platelet Ratio Predict Cardiovascular Events in Hemodialysis Patients","volume":"20","author":"Zhu","year":"2020","journal-title":"Exp. Ther. Med."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"506","DOI":"10.5301\/jva.5000413","article-title":"Cephalic Vein and Radial Artery Diameter in Formation of Radiocephalic Arteriovenous Fistula: A Systematic Review","volume":"16","author":"Kordzadeh","year":"2015","journal-title":"J. Vasc. Access"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1067\/mva.2002.126544","article-title":"Prediction of Wrist Arteriovenous Fistula Maturation with Preoperative Vein Mapping with Ultrasonography","volume":"36","author":"Mendes","year":"2002","journal-title":"J. Vasc. Surg."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.ejvs.2006.09.001","article-title":"Pre-Operative Radial Arterial Diameter Predicts Early Failure of Arteriovenous Fistula (AVF) for Haemodialysis","volume":"33","author":"Parmar","year":"2007","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S1078-5884(96)80108-0","article-title":"Factors Associated with Early Failure of Arteriovenous Fistulae for Haemodialysis Access","volume":"12","author":"Wong","year":"1996","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.ejvs.2018.06.066","article-title":"Diameter Criteria Have Limited Value for Prediction of Functional Dialysis Use of Arteriovenous Fistulas","volume":"56","author":"Wilmink","year":"2018","journal-title":"Eur. J. Vasc. Endovasc. Surg."},{"key":"ref_67","first-page":"942950","article-title":"Relationship between Vessel Diameter and Time to Maturation of Arteriovenous Fistula for Hemodialysis Access","volume":"2012","author":"Gholipour","year":"2012","journal-title":"Int. J. Nephrol."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1007\/s11255-021-03002-6","article-title":"Prognostic Nutritional Index Is a Predictor of Mortality in Elderly Patients with Chronic Kidney Disease","volume":"54","author":"Tugcu","year":"2022","journal-title":"Int. Urol. Nephrol."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jjcc.2018.01.012","article-title":"Relationship between the Prognostic Nutritional Index and Long-Term Clinical Outcomes in Patients with Stable Coronary Artery Disease","volume":"72","author":"Wada","year":"2018","journal-title":"J. Cardiol."}],"container-title":["Life"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-1729\/12\/9\/1447\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:34:01Z","timestamp":1760142841000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-1729\/12\/9\/1447"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,18]]},"references-count":69,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2022,9]]}},"alternative-id":["life12091447"],"URL":"https:\/\/doi.org\/10.3390\/life12091447","relation":{},"ISSN":["2075-1729"],"issn-type":[{"value":"2075-1729","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,18]]}}}