{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T10:50:58Z","timestamp":1777027858141,"version":"3.51.4"},"reference-count":57,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2022,9,27]],"date-time":"2022-09-27T00:00:00Z","timestamp":1664236800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Introduction: Our aim was to investigate the applicability of artificial intelligence in predicting obstructive sleep apnoea (OSA) and upper airway obstruction using ultrasound (US) measurements of subcutaneous adipose tissues (SAT) in the regions of the neck, chest and abdomen. Methods: One hundred patients were divided into mild (32), moderately severe-severe (32) OSA and non-OSA (36), according to the results of the polysomnography. These patients were examined using anthropometric measurements and US of SAT and drug-induced sleep endoscopy. Results: Using SAT US and anthropometric parameters, oropharyngeal obstruction could be predicted in 64% and tongue-based obstruction in 72%. In predicting oropharyngeal obstruction, BMI, abdominal and hip circumferences, submental SAT and SAT above the second intercostal space on the left were identified as essential parameters. Furthermore, tongue-based obstruction was predicted mainly by height, SAT measured 2 cm above the umbilicus and submental SAT. The OSA prediction was successful in 97% using the parameters mentioned above. Moreover, other parameters, such as US-based SAT, with SAT measured 2 cm above the umbilicus and both-sided SAT above the second intercostal spaces as the most important ones. Discussion: Based on our results, several categories of OSA can be predicted using artificial intelligence with high precision by using SAT and anthropometric parameters.<\/jats:p>","DOI":"10.3390\/life12101504","type":"journal-article","created":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T01:51:49Z","timestamp":1664329909000},"page":"1504","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["The Predictive Role of Subcutaneous Adipose Tissue in the Pathogenesis of Obstructive Sleep Apnoea"],"prefix":"10.3390","volume":"12","author":[{"given":"Vikt\u00f3ria","family":"Moln\u00e1r","sequence":"first","affiliation":[{"name":"Department of Otolaryngology and Head and Neck Surgery, Semmelweis University, 1083 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zolt\u00e1n","family":"Lakner","sequence":"additional","affiliation":[{"name":"Szent Istv\u00e1n Campus, Hungarian University of Agriculture and Life Sciences, 2100 G\u00f6d\u00f6ll\u0151, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e1s","family":"Moln\u00e1r","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology and Head and Neck Surgery, Semmelweis University, 1083 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7001-7647","authenticated-orcid":false,"given":"D\u00e1vid L\u00e1szl\u00f3","family":"T\u00e1rnoki","sequence":"additional","affiliation":[{"name":"Medical Imaging Centre, Semmelweis University, 1083 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5909-3780","authenticated-orcid":false,"given":"\u00c1d\u00e1m Domonkos","family":"T\u00e1rnoki","sequence":"additional","affiliation":[{"name":"Medical Imaging Centre, Semmelweis University, 1083 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3","family":"Kunos","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, Pulmonology Hospital of T\u00f6r\u00f6kb\u00e1lint, 2045 T\u00f6r\u00f6kb\u00e1lint, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3","family":"Tam\u00e1s","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology and Head and Neck Surgery, Semmelweis University, 1083 Budapest, Hungary"},{"name":"Department of Voice, Speech and Swallowing Therapy, Faculty of Health Sciences, Semmelweis University, 1083 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1007\/s11325-021-02412-1","article-title":"Obstructive sleep apnea syndrome in non-obese patients","volume":"26","author":"Antonaglia","year":"2021","journal-title":"Sleep Breath"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s11325-020-02050-z","article-title":"Polysomnographic risk factors for vigilance-related cognitive decline and obstructive sleep apnea","volume":"25","author":"McCloy","year":"2021","journal-title":"Sleep Breath"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1007\/s11325-020-02275-y","article-title":"Obstructive sleep apnea syndrome as a potential cause of sexual dysfunction in women","volume":"25","author":"Kabak","year":"2021","journal-title":"Sleep Breath"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1753-4887.2011.00456.x","article-title":"Global nutrition transition and the pandemic of obesity in developing countries","volume":"70","author":"Popkin","year":"2012","journal-title":"Nutr. 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