{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T06:56:56Z","timestamp":1776754616984,"version":"3.51.2"},"reference-count":75,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T00:00:00Z","timestamp":1664323200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Thoracic aortic dissection (AD) is associated with increased morbidity and mortality. Acute aortic syndrome is the first presentation of the disease in most cases. While acute AD management follows concrete guidelines because of its urgent and life-threatening nature, chronic AD is usually overlooked, although it concerns a wide spectrum of patients surviving an acute event. Acute AD survivors ultimately enter a chronic aortic disease course. Patients with chronic thoracic AD (CTAD) require lifelong surveillance and a proportion of them may present with symptoms and late complications demanding further surgical or endovascular treatment. However, the available data concerning the management of CTAD is sparse in the literature. The management of patients with CTAD is challenging as far as determining the best medical therapy and deciding on intervention are concerned. Until recently, there were no guidelines or recommendations for imaging surveillance in patients with chronic AD. The diagnostic methods for imaging aortic diseases have been improved, while the data on new endovascular and surgical approaches has increased significantly. In this review, we summarize the current evidence in the diagnosis and management of CTAD and the latest recommendations for the surgical\/endovascular aortic repair of CTAD.<\/jats:p>","DOI":"10.3390\/life12101511","type":"journal-article","created":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T22:53:19Z","timestamp":1664405599000},"page":"1511","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Chronic Thoracic Aortic Dissection: How to Treat, When to Intervene"],"prefix":"10.3390","volume":"12","author":[{"given":"Panteleimon E.","family":"Papakonstantinou","sequence":"first","affiliation":[{"name":"Second Cardiology Department, Evangelismos Hospital, 106 76 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitra","family":"Benia","sequence":"additional","affiliation":[{"name":"First Cardiology Department, Evangelismos Hospital, 106 76 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9164-4172","authenticated-orcid":false,"given":"Dimitrios","family":"Polyzos","sequence":"additional","affiliation":[{"name":"Second Cardiology Department, Evangelismos Hospital, 106 76 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos","family":"Papakonstantinou","sequence":"additional","affiliation":[{"name":"Throracic and Cardiovascular Surgery Department, Evangelismos Hospital, 106 76 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filippos-Paschalis","family":"Rorris","sequence":"additional","affiliation":[{"name":"Throracic and Cardiovascular Surgery Department, Evangelismos Hospital, 106 76 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7495-1843","authenticated-orcid":false,"given":"Fotios","family":"Toulgaridis","sequence":"additional","affiliation":[{"name":"Second Cardiology Department, Evangelismos Hospital, 106 76 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos","family":"Manousiadis","sequence":"additional","affiliation":[{"name":"Second Cardiology Department, Evangelismos Hospital, 106 76 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sotirios","family":"Xydonas","sequence":"additional","affiliation":[{"name":"Second Cardiology Department, Evangelismos Hospital, 106 76 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonios","family":"Sideris","sequence":"additional","affiliation":[{"name":"Second Cardiology Department, Evangelismos Hospital, 106 76 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2873","DOI":"10.1093\/eurheartj\/ehu281","article-title":"2014 ESC Guidelines on the diagnosis and treatment of aortic diseases: Document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. 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