{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T12:17:44Z","timestamp":1790511464223,"version":"4.1.0"},"reference-count":20,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T00:00:00Z","timestamp":1670544000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>The existence of two sequential lymphomas, one localized and one systemic, either both with B or T lymphocytes, or one with B cells and one with T cells, with the same patient, is a known possibility. The second lymphoma is often induced by immunodepression or by the initial treatment. However, the existence of two cutaneous lymphomas with different cell lines, without systemic involvement, represents an uncommon situation. In this report, we describe the case of a 37-year-old man with an initial diagnosis of PMZBCL that over 10 months also developed a MF patch\/plaque on the left leg.<\/jats:p>","DOI":"10.3390\/life12122067","type":"journal-article","created":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T03:59:46Z","timestamp":1670558386000},"page":"2067","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Primary Cutaneous B-Cell Lymphoma Co-Existing with Mycosis Fungoides\u2014A Case Report and Overview of the Literature"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8389-1563","authenticated-orcid":false,"given":"Doriana Sorina","family":"Chilom","sequence":"first","affiliation":[{"name":"Department of Dermatology, University of Medicine and Pharmacy \u201cVictor Babe\u015f\u201d, Eftimie Murgu Sq. no.2, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona Sorina","family":"Farca\u0219","sequence":"additional","affiliation":[{"name":"Department of Microscopic Morphology\u2014Genetics, Center of Genomic Medicine, University of Medicine and Pharmacy \u201cVictor Babes\u201d, Eftimie Murgu Sq. no.2, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2647-4234","authenticated-orcid":false,"given":"Nicoleta Ioana","family":"Andreescu","sequence":"additional","affiliation":[{"name":"Department of Microscopic Morphology\u2014Genetics, Center of Genomic Medicine, University of Medicine and Pharmacy \u201cVictor Babes\u201d, Eftimie Murgu Sq. no.2, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1111\/bjd.19829","article-title":"Epidemiology of cutaneous lymphoma","volume":"184","author":"Vermeer","year":"2021","journal-title":"Br. 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Hematol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1001\/archderm.141.9.1139","article-title":"Primary Cutaneous Marginal Zone B-Cell Lymphoma: Clinical and Therapeutic Features in 50 Cases","volume":"141","author":"Hoefnagel","year":"2005","journal-title":"Arch. Dermatol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"231","DOI":"10.2147\/CCID.S277667","article-title":"Dermatological Considerations in the Diagnosis and Treatment of Marginal Zone Lymphomas","volume":"14","author":"Ronchi","year":"2021","journal-title":"Clin. Cosmet. Investig. Dermatol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.5858\/arpa.2018-0283-RA","article-title":"Primary Cutaneous Composite Lymphomas","volume":"142","author":"Chen","year":"2018","journal-title":"Arch. Pathol. Lab. Med."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1136\/jcp.2005.030825","article-title":"Three coexisting lymphomas in one patient: Genetically related or only a coincidence?","volume":"59","author":"Steinhoff","year":"2006","journal-title":"J. Clin. Pathol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1111\/cup.13289","article-title":"Composite cutaneous lymphoma of diffuse large B-cell lymphoma-leg type and subcutaneous panniculitis-like T-cell lymphoma","volume":"45","author":"Szablewski","year":"2018","journal-title":"J. Cutan. Pathol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1515\/med-2020-0191","article-title":"Clinicopathological analysis of composite lymphoma: A two-case report and literature review","volume":"15","author":"Gui","year":"2020","journal-title":"Open Med."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1111\/j.1440-1827.2012.02858.x","article-title":"Clinicopathological analysis of a composite lymphoma containing both T- and B-cell lymphomas","volume":"62","author":"Suefuji","year":"2012","journal-title":"Pathol. Int."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/j.humpath.2013.11.008","article-title":"Composite lymphoid neoplasm of B-cell and T-cell origins: A pathologic study of 14 cases","volume":"45","author":"Wang","year":"2014","journal-title":"Hum. 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Oncol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1111\/ijd.13653","article-title":"Risk of cutaneous T-cell lymphoma in patients with chronic lymphocytic leukemia and other subtypes of non-Hodgkin lymphoma","volume":"56","author":"Chang","year":"2017","journal-title":"Int. J. Dermatol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"421","DOI":"10.2340\/00015555-0663","article-title":"Mycosis Fungoides with Recurrent Hodgkin\u2019s Lymphoma and Diffuse Large B-cell Lymphoma","volume":"89","author":"Miyagaki","year":"2009","journal-title":"Acta Derm. Venereol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1111\/j.1365-2133.2006.07346.x","article-title":"Mycosis fungoides associated with B-cell malignancies","volume":"155","author":"Barzilai","year":"2006","journal-title":"Br. J. Dermatol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"73","DOI":"10.3389\/fonc.2013.00073","article-title":"Radiotherapy-Induced Malignancies: Review of Clinical Features, Pathobiology, and Evolving Approaches for Mitigating Risk","volume":"3","author":"Braunstein","year":"2013","journal-title":"Front. Oncol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1186\/s13256-021-02783-9","article-title":"Composite lymphoma of T-cell rich, histiocyte-rich diffuse large B-cell lymphoma and nodular lymphocyte predominant Hodgkin lymphoma: A case report","volume":"15","author":"Esper","year":"2021","journal-title":"J. Med. Case Rep."}],"container-title":["Life"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-1729\/12\/12\/2067\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:37:04Z","timestamp":1760146624000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-1729\/12\/12\/2067"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,9]]},"references-count":20,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["life12122067"],"URL":"https:\/\/doi.org\/10.3390\/life12122067","relation":{},"ISSN":["2075-1729"],"issn-type":[{"value":"2075-1729","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,9]]}}}