{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T22:24:33Z","timestamp":1780439073471,"version":"3.54.1"},"reference-count":48,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,12,25]],"date-time":"2022-12-25T00:00:00Z","timestamp":1671926400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>A key step prior to clear aligner therapy (CAT) is the clinical examination and case selection, which includes understanding the specific orthodontic problem to be managed and the wider evaluation of oral health. Seeking CAT may further differ along sociodemographic parameters or across countries, as may perceived orthodontic treatment needs and oral health. We aimed to characterize patients seeking CAT across five European countries. Anonymized real-life data from one large CAT provider (DrSmile, Berlin, Germany) was retrospectively sampled for the period 1 November 2021\u201331 December 2021. A total of 15,015 patients (68.4% females, 31.6% males, with an age range of 18\u201381 years, median 30.0 years) were included. The cross-national comparison revealed a significant difference in gender distribution (p &lt; 0.001\/Chi-square), with the highest proportion of males in Italy (434\/1199, 36.2%) and the lowest in Poland (457\/1600, 28.6%); generally, more females sought CAT. The largest motivational factor in all countries for seeking CAT was crowding, in both males and females. By and large, patients paid out of pocket for CAT. The prevalence of caries, periodontitis, and craniomandibular dysfunction as well as the numbers of missing teeth were generally low, albeit with significant differences between sociodemographic groups and countries for caries and periodontitis. Patients seeking CAT showed a low prevalence in oral conditions but differed in their sociodemographic characteristics across countries. Dentists and orthodontists should consider these country-specific differences when planning CAT.<\/jats:p>","DOI":"10.3390\/life13010065","type":"journal-article","created":{"date-parts":[[2022,12,27]],"date-time":"2022-12-27T07:02:12Z","timestamp":1672124532000},"page":"65","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Who Seeks Clear Aligner Therapy? A European Cross-National Real-World Data Analysis"],"prefix":"10.3390","volume":"13","author":[{"given":"Martin","family":"Baxmann","sequence":"first","affiliation":[{"name":"Orthodentix, Arnoldstrasse 13b, 47906 Kempen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5418-5683","authenticated-orcid":false,"given":"Lan Huong","family":"Timm","sequence":"additional","affiliation":[{"name":"DrSmile-DZK Deutsche Zahnklinik GmbH, K\u00f6nigsallee 92a, 40212 D\u00fcsseldorf, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1223-1669","authenticated-orcid":false,"given":"Falk","family":"Schwendicke","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnostics, Digital Health and Health Services Research, Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, A\u00dfmannshauser Stra\u00dfe 4-6, 14197 Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.4103\/2141-9248.96930","article-title":"Knowledge of orthodontics as a dental specialty: A preliminary survey among LASUCOM students","volume":"2","author":"Adegbite","year":"2012","journal-title":"Ann. 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