{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T15:33:48Z","timestamp":1778168028652,"version":"3.51.4"},"reference-count":61,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,1,22]],"date-time":"2023-01-22T00:00:00Z","timestamp":1674345600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"\u201cGeorge Emil Palade\u201d University of Medicine, Pharmacy, Science and Technology of T\u00e2rgu Mure\u0219","award":["3963\/03.06.2020"],"award-info":[{"award-number":["3963\/03.06.2020"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>(1) Background: Cognitive dysfunction is a major concern in hypertensive patients. Lifestyle habits and nutrition influence laboratory parameters, with an impact on clinical course. The objective of the study was to evaluate nutrition and lifestyle habits in hypertensive patients with\/without cognitive dysfunction and establish correlations to laboratory parameters. Material and Methods: 50 patients admitted to the Cardiovascular Rehabilitation Clinic in T\u00e2rgu Mure\u0219 were enrolled in this study between March\u2013June 2021. We evaluated their cognitive function, and they filled in a questionnaire about lifestyle and nutrition. Biochemical blood tests were performed using a Konelab Prime 60i analyzer. IBM-SPSS22 and GraphPad InStat3 were used for statistics. Results: Mean age of hypertensive patients (n = 50) was 70.42 \u00b1 4.82 (SD) years, half of them had cognitive dysfunction. Zinc deficiency was present in 74% of the subjects. The subgroup with cognitive dysfunction had significantly higher BMI (p = 0.009) and microalbuminuria (p = 0.0479), as well as significantly lower magnesium intake (p = 0.032) and cholesterol intake (p = 0.022), compared to those with normal cognitive status. Conclusions: Nutrition is in a close relationship with laboratory parameters; significant differences (microalbuminuria, cholesterol intake, BMI, etc.) are present between hypertensive patients with\/without cognitive dysfunction. A healthy diet is important for the maintenance of metabolic balance, the achievement of optimal body weight, and the prevention of complications.<\/jats:p>","DOI":"10.3390\/life13020311","type":"journal-article","created":{"date-parts":[[2023,1,23]],"date-time":"2023-01-23T03:26:41Z","timestamp":1674444401000},"page":"311","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Relationship between Nutrition, Lifestyle Habits and Laboratory Parameters in Hypertensive Patients with\/without Cognitive Dysfunction"],"prefix":"10.3390","volume":"13","author":[{"given":"Kinga-Ilona","family":"Nyulas","sequence":"first","affiliation":[{"name":"Doctoral School of GE Palade University of Medicine, Pharmacy, Science, and Technology of T\u00e2rgu Mure\u015f, 540136 T\u00e2rgu Mure\u015f, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rta","family":"Germ\u00e1n-Sall\u00f3","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II, Faculty of Medicine, GE Palade University of Medicine, Pharmacy, Science, and Technology of T\u00e2rgu Mure\u015f, 540136 T\u00e2rgu Mure\u015f, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zita","family":"Fazakas","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Chemistry of Environmental Factors, Faculty of Pharmacy, GE Palade University of Medicine, Pharmacy, Science, and Technology of T\u00e2rgu Mure\u015f, 540136 T\u00e2rgu Mure\u015f, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zolt\u00e1n","family":"Preg","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Faculty of Medicine, GE Palade University of Medicine, Pharmacy, Science, and Technology of T\u00e2rgu Mure\u015f, 540136 T\u00e2rgu Mure\u015f, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T\u00fcnde","family":"P\u00e1l","sequence":"additional","affiliation":[{"name":"Emergency Institute for Cardiovascular Diseases and Transplantation, GE Palade University of Medicine, Pharmacy, Science, and Technology of T\u00e2rgu Mure\u015f, 540136 T\u00e2rgu Mure\u015f, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3993-7947","authenticated-orcid":false,"given":"S\u00e1ndor","family":"P\u00e1l","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Department of Transfusion Medicine, Medical School, University of P\u00e9cs, H-7622 P\u00e9cs, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert Gabriel","family":"Tripon","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine, GE Palade University of Medicine, Pharmacy, Science, and Technology of T\u00e2rgu Mure\u015f, 540136 T\u00e2rgu Mure\u015f, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margit Judit","family":"Cseh","sequence":"additional","affiliation":[{"name":"Nutrition and Dietetics Deparment, GE Palade University of Medicine, Pharmacy, Science, and Technology of T\u00e2rgu Mure\u015f, 540136 T\u00e2rgu Mure\u015f, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6655-5987","authenticated-orcid":false,"given":"Zsuzs\u00e1nna","family":"Simon-Szab\u00f3","sequence":"additional","affiliation":[{"name":"Department of Pathophysiology, Faculty of Medicine, GE Palade University of Medicine, Pharmacy, Science, and Technology of T\u00e2rgu Mure\u015f, 540136 T\u00e2rgu Mure\u015f, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1664-8130","authenticated-orcid":false,"given":"Emil Marian","family":"Arb\u0103na\u0219i","sequence":"additional","affiliation":[{"name":"Clinic of Vascular Surgery, Mure\u0219 County Emergency Hospital, 540136 T\u00e2rgu Mure\u0219, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enik\u0151","family":"Nemes-Nagy","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Medical Biochemistry, Faculty of Medicine in English, GE Palade University of Medicine, Pharmacy, Science, and Technology of T\u00e2rgu Mure\u015f, 540136 T\u00e2rgu Mure\u015f, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1097\/01.hjh.0000434937.62412.24","article-title":"Hypertension prevalence and control in Romania at a seven-year interval. 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