{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:17:25Z","timestamp":1777400245440,"version":"3.51.4"},"reference-count":72,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,1,22]],"date-time":"2023-01-22T00:00:00Z","timestamp":1674345600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"the 7th Own Research Plan of the University of Seville"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Presbyopia can be defined as the refractive state of the eye in which, due to a physiological decrease in the ability to accommodate, it is not possible to sustain vision without fatigue in a prolonged manner, along with difficulty focusing near vision. It is estimated that its prevalence in 2030 will be approximately 2.1 billion people. Corneal inlays are an alternative in the correction of presbyopia. They are implanted beneath a laser-assisted in situ keratomileusis (LASIK) flap or in a pocket in the center of the cornea of the non-dominant eye. The purpose of this review is to provide information about intraoperative and postoperative KAMRA inlay complications in the available scientific literature. A search was conducted on PubMed, Web of Science, and Scopus with the following search strategy: (\"KAMRA inlay\" OR \u201cKAMRA\u201d OR \u201ccorneal inlay pinhole\u201d OR \u201cpinhole effect intracorneal\u201d OR \u201cSAICI\u201d OR \u201csmall aperture intracorneal inlay\u201d) AND (\u201ccomplication\u201d OR \u201cexplantation\u201d OR \u201cexplanted\u201d OR \u201cretired\u201d). The bibliography consulted shows that the insertion of a KAMRA inlay is an effective procedure that improves near vision with a slight decrease in distance vision. However, postoperative complications such as corneal fibrosis, epithelial iron deposits, and stromal haze are described.<\/jats:p>","DOI":"10.3390\/life13020312","type":"journal-article","created":{"date-parts":[[2023,1,23]],"date-time":"2023-01-23T03:26:41Z","timestamp":1674444401000},"page":"312","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Complications of Small Aperture Intracorneal Inlays: A Literature Review"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9453-8615","authenticated-orcid":false,"given":"Mar\u00eda Carmen","family":"S\u00e1nchez-Gonz\u00e1lez","sequence":"first","affiliation":[{"name":"Department of Physics of Condensed Matter, Optics Area, University of Seville, 41012 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4851-680X","authenticated-orcid":false,"given":"Estanislao","family":"Guti\u00e9rrez-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Department of Surgery, Ophthalmology Area, University of Seville, 41009 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0450-7717","authenticated-orcid":false,"given":"Jos\u00e9-Mar\u00eda","family":"S\u00e1nchez-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Department of Physics of Condensed Matter, Optics Area, University of Seville, 41012 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Concepci\u00f3n","family":"De-Hita-Cantalejo","sequence":"additional","affiliation":[{"name":"Department of Physics of Condensed Matter, Optics Area, University of Seville, 41012 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana-Mar\u00eda","family":"Pinero-Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Department of Surgery, Ophthalmology Area, University of Seville, 41009 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9594-1601","authenticated-orcid":false,"given":"Timoteo","family":"Gonz\u00e1lez-Cruces","sequence":"additional","affiliation":[{"name":"Department of Anterior Segment, Cornea and Refractive Surgery, Hospital La Arruzafa, 14012 Cordoba, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ra\u00fal","family":"Capote-Puente","sequence":"additional","affiliation":[{"name":"Department of Physics of Condensed Matter, Optics Area, University of Seville, 41012 Seville, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1111\/cxo.12987","article-title":"Correction of presbyopia: Old problems with old (and new) solutions","volume":"103","author":"Kollbaum","year":"2020","journal-title":"Clin. 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