{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T22:00:41Z","timestamp":1784066441931,"version":"3.55.0"},"reference-count":83,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T00:00:00Z","timestamp":1678320000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Research, Development and Innovation Office by Hungarian Ministry","award":["FK129061"],"award-info":[{"award-number":["FK129061"]}]},{"name":"National Research, Development and Innovation Office by Hungarian Ministry","award":["T\u00c1MOP 4.2.4.A\/2-11-1-2012-0001"],"award-info":[{"award-number":["T\u00c1MOP 4.2.4.A\/2-11-1-2012-0001"]}]},{"name":"European Social Fund","award":["FK129061"],"award-info":[{"award-number":["FK129061"]}]},{"name":"European Social Fund","award":["T\u00c1MOP 4.2.4.A\/2-11-1-2012-0001"],"award-info":[{"award-number":["T\u00c1MOP 4.2.4.A\/2-11-1-2012-0001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>L-aminoguanidine (AG) is an inhibitor frequently used for investigating plant abiotic stress responses; however, its exact mode of action is not well understood. Many studies used this compound as a specific diamine oxidase inhibitor, whereas other studies used it for reducing nitric oxide (NO) production. Recent studies suggest its antiglycation effect; however, this remains elusive in plants. This review summarises our current knowledge about different targets of AG in plants. Our recommendation is to use AG as a modulator of polyamine-related mechanisms rather than a specific inhibitor. In the future overall investigation is needed to decipher the exact mechanisms of AG. More careful application of AG could give more insight into plant abiotic stress responses.<\/jats:p>","DOI":"10.3390\/life13030747","type":"journal-article","created":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T03:02:08Z","timestamp":1678417328000},"page":"747","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["More Than a Diamine Oxidase Inhibitor: L-Aminoguanidine Modulates Polyamine-Related Abiotic Stress Responses of Plants"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8299-105X","authenticated-orcid":false,"given":"Zolt\u00e1n M\u00e1rton","family":"K\u00f6hler","sequence":"first","affiliation":[{"name":"Department of Biochemistry, Albert Szent-Gyorgyi Medical School, University of Szeged, H-6720 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3043-4857","authenticated-orcid":false,"given":"\u00c1gnes","family":"Szepesi","sequence":"additional","affiliation":[{"name":"Department of Plant Biology, Institute of Biology, Faculty of Science and Informatics, University of Szeged, K\u00f6z\u00e9p fasor 52, H-6726 Szeged, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1007\/s000110050495","article-title":"Biological effects of aminoguanidine: An update","volume":"48","author":"Nilsson","year":"1999","journal-title":"Inflamm. 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