{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:11:39Z","timestamp":1760148699828,"version":"build-2065373602"},"reference-count":16,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2023,5,22]],"date-time":"2023-05-22T00:00:00Z","timestamp":1684713600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>(1) Background: Physiological changes in nasal patency in response to posture contribute to sleep-related problems. Previously, we reported that the supine and prone positions cause a significant decrease in nasal patency in subjective and objective assessments of healthy individuals. Therefore, we conducted a study to evaluate the effect of posture on nasal patency in patients with allergic rhinitis (AR); (2) Methods: The present study comprised 30 patients diagnosed with AR and 30 healthy subjects without nasal disease (non-AR). Changes in nasal patency were evaluated in the sitting, supine, and prone positions. We used the visual analog scale to evaluate subjective nasal blockage. Acoustic rhinometry and endoscopy were used to objectively measure changes in nasal patency; (3) Results: In the non-AR group, the prone position had a significant effect on subjective nasal blockage compared with the sitting position, with significant decreases in the minimal cross-sectional area (mCSA) measured by acoustic rhinometry. Furthermore, endoscopy demonstrated a significantly increased inferior turbinate hypertrophy in the non-AR group. In the AR group, there was no statistical difference in subjective nasal blockage symptoms between the different positions. However, in objective examinations (acoustic rhinometry and endoscopy), the prone position showed significantly decreased nasal patency; (4) Conclusions: In patients with AR, subjective nasal blockage did not significantly increase in the supine or prone position. Endoscopy demonstrated increased inferior turbinate hypertrophy in supine and prone positions resulting in a significant reduction in nasal cavity mCSA, indicating an objective reduction in nasal patency.<\/jats:p>","DOI":"10.3390\/life13051226","type":"journal-article","created":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T01:36:48Z","timestamp":1684805808000},"page":"1226","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Nasal Patency in Sitting, Supine, and Prone Positions in Individuals with and without Allergic Rhinitis"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6190-4351","authenticated-orcid":false,"given":"Yun-Ting","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Chang Gung Memorial Hospital, Chiayi 613, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yao-Te","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Chang Gung Memorial Hospital, Chiayi 613, Taiwan"},{"name":"Faculty of Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3792-3784","authenticated-orcid":false,"given":"Cheng-Ming","family":"Hsu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Chang Gung Memorial Hospital, Chiayi 613, Taiwan"},{"name":"Faculty of Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan"},{"name":"Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming-Shao","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Chang Gung Memorial Hospital, Chiayi 613, Taiwan"},{"name":"Faculty of Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan"},{"name":"Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsin-Yi","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Chang Gung Memorial Hospital, Chiayi 613, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5939-9747","authenticated-orcid":false,"given":"Geng-He","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Chang Gung Memorial Hospital, Chiayi 613, Taiwan"},{"name":"Faculty of Medicine, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan"},{"name":"Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan"},{"name":"Head and Neck Infection Treatment Center, Chang Gung Memorial Hospital, Chiayi 613, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s00405-008-0701-1","article-title":"Altered positional regulation of nasal patency in patients with obstructive sleep apnoea syndrome","volume":"266","author":"Hellgren","year":"2009","journal-title":"Eur. 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Rev."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/S1808-8694(15)31203-9","article-title":"Effects of posture change on nasal patency","volume":"71","author":"Roithmann","year":"2005","journal-title":"Braz. J. Otorhinolaryngol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2500\/ajr.2008.22.3143","article-title":"Effect of postural change on nasal airway and autonomic nervous system established by rhinomanometry and heart rate variability analysis","volume":"22","author":"Ko","year":"2008","journal-title":"Am. J. Rhinol."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Chang, G.-H., Hsu, C.-M., Huang, E.I., Tsai, H.-Y., Wang, Y.-T., Tsai, M.-S., Chang, P.-J., and Tsai, Y.-T. (2021). Effects of Supine and Prone Positions on Nasal Patency in Healthy Individuals. Ear. Nose Throat J., 01455613211015437.","DOI":"10.1177\/01455613211015437"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"114116","DOI":"10.1016\/j.jep.2021.114116","article-title":"Nasal irrigation with Glycyrrhiza glabra extract for treatment of allergic rhinitis\u2014A study of in vitro, in vivo and clinical trial","volume":"275","author":"Chang","year":"2021","journal-title":"J. Ethnopharmacol."},{"key":"ref_9","first-page":"41","article-title":"VAS for assessing the perception of antihistamines use in allergic rhinitis","volume":"90","author":"Ciprandi","year":"2019","journal-title":"Acta Biomed."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1007\/s40629-016-0006-7","article-title":"Visual analogue scales (VAS): Measuring instruments for the documentation of symptoms and therapy monitoring in cases of allergic rhinitis in everyday health care","volume":"26","author":"Klimek","year":"2017","journal-title":"Allergo. J. 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