{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:25:23Z","timestamp":1760149523800,"version":"build-2065373602"},"reference-count":34,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T00:00:00Z","timestamp":1692230400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Viral hepatitis continues to be the leading cause of morbidity and mortality worldwide, but the burden has significantly diminished thanks to the large-scale use of vaccines and antivirals. However, there are still challenges regarding viral hepatitis management, especially when more than one pathogenic agent is involved. We present the case of a 45-year-old woman who had a simultaneous infection involving three hepatitis viruses: HAV, HBV, and HEV.<\/jats:p>","DOI":"10.3390\/life13081761","type":"journal-article","created":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T10:15:48Z","timestamp":1692267348000},"page":"1761","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Surprising Case of Triple Acute Hepatitis Infection"],"prefix":"10.3390","volume":"13","author":[{"given":"Ion","family":"\u0218tefan","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, \u2018Dr. Carol Davila\u2019 Central Military Emergency University Hospital, 134 Calea Plevnei, 010242 Bucharest, Romania"},{"name":"Department of Medico-Surgical and Prophylactic Disciplines, Titu Maiorescu University, 040441 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioana-M\u0103d\u0103lina","family":"Cristea","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, \u2018Dr. Carol Davila\u2019 Central Military Emergency University Hospital, 134 Calea Plevnei, 010242 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexia-Teodora","family":"\u0218tefan","sequence":"additional","affiliation":[{"name":"Faculty of General Medicine, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aurelian-Emil","family":"Ranetti","sequence":"additional","affiliation":[{"name":"Endocrinologic Department, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1982-1066","authenticated-orcid":false,"given":"Carmen Adella","family":"Sirbu","sequence":"additional","affiliation":[{"name":"Clinical Neurosciences Department, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania"},{"name":"Academy of Romanian Scientists, 50044 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Rusu","sequence":"additional","affiliation":[{"name":"Department of Preclinical Disciplines, Titu Maiorescu University, 040441 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1362-6427","authenticated-orcid":false,"given":"Cosmin Alec","family":"Moldovan","sequence":"additional","affiliation":[{"name":"Department of Medico-Surgical and Prophylactic Disciplines, Titu Maiorescu University, 040441 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Polliana M.","family":"Leru","sequence":"additional","affiliation":[{"name":"Clinical Department, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Colentina Clinical Hospital, 020125 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudiu-Eduard","family":"Nistor","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Department, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.1016\/S0140-6736(18)31694-5","article-title":"Forecasting Life Expectancy, Years of Life Lost, and All-Cause and Cause-Specific Mortality for 250 Causes of Death: Reference and Alternative Scenarios for 2016\u201340 for 195 Countries and Territories","volume":"392","author":"Foreman","year":"2018","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1056\/NEJMra1204512","article-title":"Hepatitis E","volume":"367","author":"Hoofnagle","year":"2012","journal-title":"N. 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