{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T05:11:10Z","timestamp":1791090670156,"version":"4.1.0"},"reference-count":17,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2023,9,20]],"date-time":"2023-09-20T00:00:00Z","timestamp":1695168000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Male infertility is a condition that has always been less studied and known than female infertility. Male infertility is increasingly present and increasingly diagnosed. Although several causes are known, to date about 40% of the causes are considered idiopathic. The worldwide denasality can only be slowed if awareness campaigns are implemented on all the diseases that can alter fertile potential, especially in young adolescents. Male infertility is, in addition, associated with several medical conditions. In particular, the association between infertility and testicular cancer, cardiovascular disease, autoimmune diseases, and genetic diseases is well known. For this reason, fertility preservation should not be proposed or be only oncological in nature, as there are several diagnosable pediatric pathologies that are associated with altered fertile potential to whose patients we could offer a gamete preservation pathway. In this paper we propose our experience on fertility preservation in pediatric andrological diseases.<\/jats:p>","DOI":"10.3390\/life13091934","type":"journal-article","created":{"date-parts":[[2023,9,19]],"date-time":"2023-09-19T23:11:52Z","timestamp":1695165112000},"page":"1934","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Fertility Preservation in Pediatric Age: Future Perspective among Andrological Diseases"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0296-3789","authenticated-orcid":false,"given":"Nicola","family":"Zampieri","sequence":"first","affiliation":[{"name":"Pediatric Surgical Unit, Pediatric Fertility Lab, Department of Engineering for Innovation Medicine, University of Verona, Piazzale Stefani, n. 1, 37100 Verona, Italy"},{"name":"Pediatric and Infant Surgery, UniCamillus International Medical University, Via di Sant\u2019Alessandro 8, 00131 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,9,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.fertnstert.2020.01.003","article-title":"The pediatric patient and future fertility: Optimizing long-term male reproductive health outcomes","volume":"113","author":"Nassau","year":"2020","journal-title":"Fertil. Steril."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e57","DOI":"10.1016\/S1470-2045(20)30582-9","article-title":"Fertility preservation for male patients with childhood, adolescent, and young adult cancer: Recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group","volume":"22","author":"Mulder","year":"2021","journal-title":"Lancet Oncol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1089\/jayao.2017.0117","article-title":"Fertility Preservation in Pediatric Oncology Patients: New Perspectives","volume":"7","author":"Gertosio","year":"2018","journal-title":"Adolesc. Young Adult Oncol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"854186","DOI":"10.3389\/fendo.2022.854186","article-title":"Testicular Tissue Banking for Fertility Preservation in Young Boys: Which Patients Should Be Included?","volume":"13","author":"Delgouffe","year":"2022","journal-title":"Front. Endocrinol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1016\/j.fertnstert.2021.03.026","article-title":"Fertility preservation in men: A contemporary overview and a look toward emerging technologies","volume":"115","author":"Brannigan","year":"2021","journal-title":"Fertil. Steril."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"hoaa016","DOI":"10.1093\/hropen\/hoaa016","article-title":"Fertility preservation in boys: Recent developments and new insights","volume":"2020","author":"Goossens","year":"2020","journal-title":"Hum. Reprod. Open"},{"key":"ref_7","first-page":"2358","article-title":"Gonadal function in pediatric Fanconi anemia patients treated with hematopoietic stem cell transplant","volume":"108","author":"Koo","year":"2023","journal-title":"Haematologica"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1093\/humupd\/dmaa003","article-title":"Review of injection techniques for spermatogonial stem cell transplantation","volume":"26","author":"Gul","year":"2020","journal-title":"Hum. Reprod. Update"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.juro.2016.09.159","article-title":"Fertility Preservation for Pediatric Patients: Current State and Future Possibilities","volume":"198","author":"Johnson","year":"2017","journal-title":"J. Urol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"520","DOI":"10.21037\/tau-20-908","article-title":"Fertility preservation for pediatric male cancer patients: Illustrating contemporary and future options; a case report","volume":"10","author":"Abdelaal","year":"2021","journal-title":"Transl. Androl. Urol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.urpr.2017.03.007","article-title":"The Landscape of Coverage for Fertility Preservation in Male Pediatric Patients","volume":"5","author":"Benoit","year":"2018","journal-title":"Urol. Pract."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1111\/andr.12371","article-title":"Ethical, moral, and theological insights into advances in male pediatric and adolescent fertility preservation","volume":"5","author":"Ramstein","year":"2017","journal-title":"Andrology"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1093\/humrep\/dev161","article-title":"Fertility preservation in the male pediatric population: Factors influencing the decision of parents and children","volume":"30","author":"Wyns","year":"2015","journal-title":"Hum. Reprod."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Errico, A., Vinco, S., Ambrosini, G., Dalla Pozza, E., Marroncelli, N., Zampieri, N., and Dando, I. (2023). Mitochondrial Dynamics as Potential Modulators of Hormonal Therapy Effectiveness in Males. Biology, 12.","DOI":"10.3390\/biology12040547"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"e14244","DOI":"10.1111\/and.14244","article-title":"A new frontier in therapy personalisation based on in vitro studies to preserve fertility potential of men","volume":"54","author":"Zampieri","year":"2022","journal-title":"Andrologia"},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Errico, A., Camoglio, F.S., Zampieri, N., and Dando, I. (2022). Testicular Torsion: Preliminary Results of In Vitro Cell Stimulation Using Chorionic Gonadotropin. Cells, 11.","DOI":"10.3390\/cells11030450"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"e14209","DOI":"10.1111\/and.14209","article-title":"Twenty-year experience with macro-area school screening for andrological disease in paediatric age","volume":"53","author":"Zampieri","year":"2021","journal-title":"Andrologia"}],"container-title":["Life"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-1729\/13\/9\/1934\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T20:54:07Z","timestamp":1760129647000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-1729\/13\/9\/1934"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,20]]},"references-count":17,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2023,9]]}},"alternative-id":["life13091934"],"URL":"https:\/\/doi.org\/10.3390\/life13091934","relation":{},"ISSN":["2075-1729"],"issn-type":[{"value":"2075-1729","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,20]]}}}