{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T16:04:44Z","timestamp":1791821084599,"version":"4.3.4"},"reference-count":51,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T00:00:00Z","timestamp":1697673600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>A thrombophilic woman is more likely to experience difficulties during pregnancy, difficulties that will also affect the development of the newborn. This study aims to compare maternal and newborn characteristics between healthy and thrombophilic pregnancy. The following characteristics were analysed: maternal characteristics (BMI- body mass index, haemostasis parameters, thrombophilia-specific treatment) and newborn characteristics (gestational period, birth weight, the Apgar score). This follow-up study spanning five years, from 2018 to 2022, focuses on a cohort of 500 women who underwent delivery hospitalization in the western region of Romania. The maternal characteristics influence the newborn: the greater the weight of the mother with thrombophilia, the more the chances that the fetus will have a lower birth weight; increasing the dose of LMWH (low molecular weight heparin), connected with the necessity to control the homeostasis parameters, the more likely the fetus will be born with a lower birth weight. A pregnant woman with thrombophilia, treated appropriately, having a normal weight, and not presenting other risk factors independent of thrombophilia, will have a newborn with characteristics similar to a healthy pregnant woman.<\/jats:p>","DOI":"10.3390\/life13102082","type":"journal-article","created":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T11:46:26Z","timestamp":1697715986000},"page":"2082","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Maternal and Newborn Characteristics\u2014A Comparison between Healthy and Thrombophilic Pregnancy"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5358-882X","authenticated-orcid":false,"given":"Miruna","family":"Samfireag","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Discipline of Clinical Practical Skills, \u201cVictor Babes\u201d University of Medicine and Pharmacy, No. 2 Eftimie Murgu Square, 300041 Timisoara, Romania"},{"name":"Advanced Cardiology and Hemostaseology Research Center, \u201cVictor Babes\u201d University of Medicine and Pharmacy, No. 2 Eftimie Murgu Square, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5508-1344","authenticated-orcid":false,"given":"Ovidiu","family":"Potre","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Discipline of Hematology, \u201cVictor Babes\u201d University of Medicine and Pharmacy, No. 2 Eftimie Murgu Square, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Potre","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Discipline of Hematology, \u201cVictor Babes\u201d University of Medicine and Pharmacy, No. 2 Eftimie Murgu Square, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radu-Dumitru","family":"Moleriu","sequence":"additional","affiliation":[{"name":"Department III of Functional Sciences, Discipline of Medical Informatics and Biostatistics, \u201cVictor Babes\u201d University of Medicine and Pharmacy, No. 2 Eftimie Murgu Square, 300041 Timisoara, Romania"},{"name":"Faculty of Mathematics and Computer Science, Department of Computer Science, West University of Timisoara, No. 4 Vasile Parvan Boulevard, 300223 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Izabella","family":"Petre","sequence":"additional","affiliation":[{"name":"Department XII of Obstetrics and Gynaecology, Discipline III of Obstetrics and Gynaecology, \u201cVictor Babes\u201d University of Medicine and Pharmacy, No. 2 Eftimie Murgu Square, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ema","family":"Borsi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Discipline of Hematology, \u201cVictor Babes\u201d University of Medicine and Pharmacy, No. 2 Eftimie Murgu Square, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7753-7621","authenticated-orcid":false,"given":"Teodora","family":"Hoinoiu","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Discipline of Clinical Practical Skills, \u201cVictor Babes\u201d University of Medicine and Pharmacy, No. 2 Eftimie Murgu Square, 300041 Timisoara, Romania"},{"name":"Advanced Cardiology and Hemostaseology Research Center, \u201cVictor Babes\u201d University of Medicine and Pharmacy, No. 2 Eftimie Murgu Square, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ion","family":"Petre","sequence":"additional","affiliation":[{"name":"Department III of Functional Sciences, Discipline of Medical Informatics and Biostatistics, \u201cVictor Babes\u201d University of Medicine and Pharmacy, No. 2 Eftimie Murgu Square, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tudor-Alexandru","family":"Popoiu","sequence":"additional","affiliation":[{"name":"Department III of Functional Sciences, Discipline of Medical Informatics and Biostatistics, \u201cVictor Babes\u201d University of Medicine and Pharmacy, No. 2 Eftimie Murgu Square, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stela","family":"Iurciuc","sequence":"additional","affiliation":[{"name":"Department VI of Cardiology, Discipline of Internal Medicine and Ambulatory Care, Prevention and Cardiovascular Recovery, \u201cVictor Babes\u201d University of Medicine and Pharmacy, No. 2 Eftimie Murgu Square, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei","family":"Anghel","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Pharmacology, Discipline of Biochemistry, \u201cVictor Babes\u201d University of Medicine and Pharmacy, No. 2 Eftimie Murgu Square, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,10,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1515\/dx-2018-0099","article-title":"Understanding the \u201cphilosophy\u201d of laboratory hemostasis","volume":"6","author":"Lippi","year":"2019","journal-title":"Diagnosis"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-1-4939-7196-1_1","article-title":"Overview of Hemostasis and Thrombosis and Contribution of Laboratory Testing to 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