{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:41:11Z","timestamp":1760150471702,"version":"build-2065373602"},"reference-count":19,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2023,12,8]],"date-time":"2023-12-08T00:00:00Z","timestamp":1701993600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Monkeypox (Mpox) is a virus that first emerged in Africa in 1970 [...]<\/jats:p>","DOI":"10.3390\/life13122308","type":"journal-article","created":{"date-parts":[[2023,12,8]],"date-time":"2023-12-08T03:03:33Z","timestamp":1702004613000},"page":"2308","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Monkeypox Entry and Emergence Preparation in Pakistan"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6798-2991","authenticated-orcid":false,"given":"Saadullah","family":"Khattak","sequence":"first","affiliation":[{"name":"Henan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1230-1666","authenticated-orcid":false,"given":"Yasir","family":"Ali","sequence":"additional","affiliation":[{"name":"National Center for Bioinformatics, Quaid-e-Azam University, Islamabad 45320, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiguang","family":"Ren","sequence":"additional","affiliation":[{"name":"Henan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin-Ying","family":"Ji","sequence":"additional","affiliation":[{"name":"Henan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475004, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,12,8]]},"reference":[{"key":"ref_1","first-page":"593","article-title":"A human infection caused by monkeypox virus in Basankusu Territory, Democratic Republic of the Congo","volume":"46","author":"Ladnyj","year":"1972","journal-title":"Bull. World Health Organ."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Khattak, S., Rauf, M.A., Ali, Y., Yousaf, M.T., Liu, Z., Wu, D.-D., and Ji, X.-Y. (2023). The monkeypox diagnosis, treatments and prevention: A review. Front. Cell. Infect. Microbiol., 12.","DOI":"10.3389\/fcimb.2022.1088471"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"e072410","DOI":"10.1136\/bmj-2022-072410","article-title":"Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: Descriptive case series","volume":"378","author":"Patel","year":"2022","journal-title":"BMJ"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1038\/s41433-022-02195-z","article-title":"Ophthalmic manifestations of monkeypox virus","volume":"37","author":"Abdelaal","year":"2023","journal-title":"Eye"},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Ali, Y., Imtiaz, H., Tahir, M.M., Gul, F., Saddozai, U.A.K., ur Rehman, A., Ren, Z.-G., Khattak, S., and Ji, X.-Y. (2023). Fragment-based approaches identified tecovirimat-competitive novel drug candidate for targeting the F13 protein of the monkeypox virus. Viruses, 15.","DOI":"10.3390\/v15020570"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"734","DOI":"10.15585\/mmwr.mm7122e1","article-title":"Use of JYNNEOS (smallpox and monkeypox vaccine, live, nonreplicating) for preexposure vaccination of persons at risk for occupational exposure to orthopoxviruses: Recommendations of the Advisory Committee on Immunization Practices\u2014United States, 2022","volume":"71","author":"Rao","year":"2022","journal-title":"Morb. Mortal. Wkly. Rep."},{"key":"ref_7","unstructured":"European Medicines Agency (2023, April 24). Tecovirimat SIGA. Available online: https:\/\/www.ema.europa.eu\/en\/medicines\/human\/EPAR\/tecovirimat-siga."},{"key":"ref_8","unstructured":"WHO (2022). Monkeypox Outbreak, WHO."},{"key":"ref_9","unstructured":"WHO (2023, April 26). Mpox (Monkeypox) Outbreak Update 2022. Available online: https:\/\/www.who.int\/emergencies\/situations\/monkeypox-oubreak-2022."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"196","DOI":"10.47262\/BL\/8.2.20220610","article-title":"Monkeypox virus preparation in Pakistan-Next viral zoonotic disease outbreak after COVID-19?","volume":"8","author":"Khattak","year":"2022","journal-title":"Biomed. Lett."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"100074","DOI":"10.1016\/j.lansea.2022.100074","article-title":"Preparedness of South East Asia countries in view of monkeypox emergence: A call for action","volume":"6","author":"Farahat","year":"2022","journal-title":"Lancet Reg. Health Southeast Asia"},{"key":"ref_12","first-page":"601","article-title":"Analysis Of The Health Care System Of Pakistan: Lessons Learnt And Way Forward","volume":"28","author":"Kurji","year":"2016","journal-title":"J. Ayub. Med. Coll Abbottabad"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"03076","DOI":"10.7189\/jogh.12.03076","article-title":"Malaria and dengue outbreaks during a national disaster in Pakistan: A rising concern for public health","volume":"12","author":"Arshad","year":"2022","journal-title":"J. Glob. Health"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s41182-022-00410-x","article-title":"The simultaneous crises of dengue and COVID-19 in Pakistan: A double hazard for the country\u2019s debilitated healthcare system","volume":"50","author":"Khatri","year":"2022","journal-title":"Trop Med. Health"},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Khattak, S., Idrees, M., Iqbal, H.I., Khan, M., Assad, N., Khan, M.N., Yousaf, M.T., Farooq, M., Yang, C.-Y., and Wu, D.-D. (2022). Assessment of Attitudes and Intentions towards COVID-19 Vaccines and Associated Factors among General Populations of Pakistan: A Cross-Sectional Study. Vaccines, 10.","DOI":"10.3390\/vaccines10101583"},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Anwar, F., Haider, F., Khan, S., Ahmad, I., Ahmed, N., Imran, M., Rashid, S., Ren, Z.-G., Khattak, S., and Ji, X.-Y. (2023). Clinical Manifestation, Transmission, Pathogenesis, and Diagnosis of Monkeypox Virus: A Comprehensive Review. Life, 13.","DOI":"10.3390\/life13020522"},{"key":"ref_17","unstructured":"News, T. (2023, April 26). Pakistan Has no Diagnostic Facility, Testing Kits to Detect Monkeypox Spread. Available online: https:\/\/www.republicworld.com\/world-news\/pakistan-news\/."},{"key":"ref_18","unstructured":"National Institutes of Health (NIH) (2022). Multicountry Monkeypox Outbreak in Non Endemic Countries."},{"key":"ref_19","unstructured":"National Institutes of Health (NIH) (2022). Laboratory Guidelines for the Detection of Monkeypox Virus."}],"container-title":["Life"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-1729\/13\/12\/2308\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T21:35:04Z","timestamp":1760132104000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-1729\/13\/12\/2308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,8]]},"references-count":19,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2023,12]]}},"alternative-id":["life13122308"],"URL":"https:\/\/doi.org\/10.3390\/life13122308","relation":{},"ISSN":["2075-1729"],"issn-type":[{"type":"electronic","value":"2075-1729"}],"subject":[],"published":{"date-parts":[[2023,12,8]]}}}