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Observations from survivors of traumatic historical events solidify that this disease is not only associated with personal experiences but can also be inherited from familial traumas. Over the past decades, researchers have focused on epigenetic inheritance to understand how responses to adverse experiences can be passed down to future generations. This review aims to present recent findings on epigenetic markers related to PTSD and research in the intergenerational inheritance of trauma. By understanding the information, we hope that epigenetic markers can act as biochemical measurements for future clinical practice.<\/jats:p>","DOI":"10.3390\/life14010098","type":"journal-article","created":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T07:59:20Z","timestamp":1704700760000},"page":"98","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Mechanisms of Epigenetic Inheritance in Post-Traumatic Stress Disorder"],"prefix":"10.3390","volume":"14","author":[{"given":"Pei-Chen","family":"Chou","sequence":"first","affiliation":[{"name":"School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1143-9073","authenticated-orcid":false,"given":"Yu-Chi","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2955-458X","authenticated-orcid":false,"given":"Sebastian","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan"},{"name":"Department of Dermatology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan"},{"name":"Master of Public Health Degree Program, National Taiwan University, Taipei 10617, Taiwan"},{"name":"Neuroscience Research Center, Kaohsiung Medical University, Kaohsiung 80708, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,1,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Varela, R.B., Cararo, J.H., Tye, S.J., Carvalho, A.F., Valvassori, S.S., Fries, G.R., and Quevedo, J. 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