{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:30:55Z","timestamp":1792805455269,"version":"4.5.0"},"reference-count":49,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T00:00:00Z","timestamp":1704758400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Fighting Blindness Ireland","award":["FB Irl"],"award-info":[{"award-number":["FB Irl"]}],"id":[{"id":"https:\/\/ror.org\/05bz3n751","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Fighting Blindness Ireland","award":["FBCRE18"],"award-info":[{"award-number":["FBCRE18"]}],"id":[{"id":"https:\/\/ror.org\/05bz3n751","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Fighting Blindness Ireland","award":["FB2020DOC"],"award-info":[{"award-number":["FB2020DOC"]}],"id":[{"id":"https:\/\/ror.org\/05bz3n751","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Fighting Blindness Ireland","award":["FBMMUH20"],"award-info":[{"award-number":["FBMMUH20"]}],"id":[{"id":"https:\/\/ror.org\/05bz3n751","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Fighting Blindness Ireland","award":["FBMMUH21"],"award-info":[{"award-number":["FBMMUH21"]}],"id":[{"id":"https:\/\/ror.org\/05bz3n751","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>(1) Background: Inherited retinal degenertions are rare conditions which may have a dramatic impact on the daily life of those affected and how they interact with their environment. Coordination of clinical services via an ophthalmic genetics multidisciplinary team (OG-MDT) allows better efficiency of time and resources to reach diagnoses and facilitate patient needs. (2) Methods: This clinical case series was conducted by a retrospective review of patient records for patients enrolled in the Target 5000 programme and managed by the OG-MDT, at the Mater Hospital Dublin, Ireland (n = 865) (3) Results: Herein we describe clinical cases and how the use of the OG-MDT optimizes care for isolated and syndromic IRD pedigrees. (4) Conclusions: this paper demonstrates the benefits of an OG-MDT to patients with IRDs resulting in the holistic resolution of complex and syndromic cases. Furthermore, we demonstrate that this format can be adopted\/developed by similar centres around the world, bringing with it the myriad benefits.<\/jats:p>","DOI":"10.3390\/life14010107","type":"journal-article","created":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T05:47:21Z","timestamp":1704865641000},"page":"107","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The Role of the Ophthalmic Genetics Multidisciplinary Team in the Management of Inherited Retinal Degenerations\u2014A Case-Based Review"],"prefix":"10.3390","volume":"14","author":[{"given":"Marcus P.","family":"Conway","sequence":"first","affiliation":[{"name":"Mater Clinical Ophthalmic Genetics Unit, Mater Misericordiae University Hospital, D07 AX57 Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7462-7725","authenticated-orcid":false,"given":"Kirk A. J.","family":"Stephenson","sequence":"additional","affiliation":[{"name":"Mater Clinical Ophthalmic Genetics Unit, Mater Misericordiae University Hospital, D07 AX57 Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6769-0577","authenticated-orcid":false,"given":"Julia","family":"Zhu","sequence":"additional","affiliation":[{"name":"Mater Clinical Ophthalmic Genetics Unit, Mater Misericordiae University Hospital, D07 AX57 Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3423-2542","authenticated-orcid":false,"given":"Adrian","family":"Dockery","sequence":"additional","affiliation":[{"name":"Mater Clinical Ophthalmic Genetics Unit, Mater Misericordiae University Hospital, D07 AX57 Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Burke","sequence":"additional","affiliation":[{"name":"Mater Clinical Ophthalmic Genetics Unit, Mater Misericordiae University Hospital, D07 AX57 Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline","family":"Turner","sequence":"additional","affiliation":[{"name":"Mater Clinical Ophthalmic Genetics Unit, Mater Misericordiae University Hospital, D07 AX57 Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francois Thai","family":"Le","sequence":"additional","affiliation":[{"name":"Eye Clinic Liasson Officer, Vision Ireland, Mater Misericordiae University Hospital, D07 AX57 Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James J.","family":"O\u2019Byrne","sequence":"additional","affiliation":[{"name":"Mater Clinical Ophthalmic Genetics Unit, Mater Misericordiae University Hospital, D07 AX57 Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Keegan","sequence":"additional","affiliation":[{"name":"Mater Clinical Ophthalmic Genetics Unit, Mater Misericordiae University Hospital, D07 AX57 Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,1,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e004015","DOI":"10.1136\/bmjopen-2013-004015","article-title":"A comparison of the causes of blindness certifications in England and Wales in working age adults (16\u201364 years), 1999\u20132000 with 2009\u20132010","volume":"4","author":"Liew","year":"2014","journal-title":"BMJ Open"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1080\/13816810.2021.1913610","article-title":"Inherited retinal diseases are the most common cause of blindness in the working-age population in Australia","volume":"42","author":"Mukhtar","year":"2021","journal-title":"Ophthalmic Genet."},{"key":"ref_3","first-page":"227","article-title":"Childhood blindness in the context of VISION 2020\u2014The right to sight","volume":"79","author":"Gilbert","year":"2001","journal-title":"Bull. 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