{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:42:09Z","timestamp":1760143329117,"version":"build-2065373602"},"reference-count":37,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T00:00:00Z","timestamp":1705449600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Research, Development and Innovation Office of Hungary","award":["NVKP_16-1-2016-0017","2020-4.1.1.-TKP2020","RRF-2.3.1-21-2022-00003","No. RRF-2.3.1-21-2022-00003","\u00daNKP-23-4-II-SE"],"award-info":[{"award-number":["NVKP_16-1-2016-0017","2020-4.1.1.-TKP2020","RRF-2.3.1-21-2022-00003","No. RRF-2.3.1-21-2022-00003","\u00daNKP-23-4-II-SE"]}]},{"name":"Ministry for Innovation and Technology in Hungary","award":["NVKP_16-1-2016-0017","2020-4.1.1.-TKP2020","RRF-2.3.1-21-2022-00003","No. RRF-2.3.1-21-2022-00003","\u00daNKP-23-4-II-SE"],"award-info":[{"award-number":["NVKP_16-1-2016-0017","2020-4.1.1.-TKP2020","RRF-2.3.1-21-2022-00003","No. RRF-2.3.1-21-2022-00003","\u00daNKP-23-4-II-SE"]}]},{"name":"Semmelweis University","award":["NVKP_16-1-2016-0017","2020-4.1.1.-TKP2020","RRF-2.3.1-21-2022-00003","No. RRF-2.3.1-21-2022-00003","\u00daNKP-23-4-II-SE"],"award-info":[{"award-number":["NVKP_16-1-2016-0017","2020-4.1.1.-TKP2020","RRF-2.3.1-21-2022-00003","No. RRF-2.3.1-21-2022-00003","\u00daNKP-23-4-II-SE"]}]},{"name":"European Union","award":["NVKP_16-1-2016-0017","2020-4.1.1.-TKP2020","RRF-2.3.1-21-2022-00003","No. RRF-2.3.1-21-2022-00003","\u00daNKP-23-4-II-SE"],"award-info":[{"award-number":["NVKP_16-1-2016-0017","2020-4.1.1.-TKP2020","RRF-2.3.1-21-2022-00003","No. RRF-2.3.1-21-2022-00003","\u00daNKP-23-4-II-SE"]}]},{"name":"the national research, development, and innovation fund","award":["NVKP_16-1-2016-0017","2020-4.1.1.-TKP2020","RRF-2.3.1-21-2022-00003","No. RRF-2.3.1-21-2022-00003","\u00daNKP-23-4-II-SE"],"award-info":[{"award-number":["NVKP_16-1-2016-0017","2020-4.1.1.-TKP2020","RRF-2.3.1-21-2022-00003","No. RRF-2.3.1-21-2022-00003","\u00daNKP-23-4-II-SE"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Background: Safety, efficacy, and patient comfort are the expectations during pulmonary vein isolation (PVI). We aimed to validate the combined advantages of pre- and periprocedural anticoagulation with non-vitamin K anticoagulants (NOACs) and rigorous left atrial appendage thrombus (LAAT) exclusion with computed tomography (CT). Methods: This study included a population of consecutive patients, between March 2018 and June 2020, who underwent cardiac CT within 24 h before PVI to guide the ablation and rule out LAAT. NOAC was omitted 24 h before the ablation. Results: A total of 187 patients (63% male) underwent CT before PVI. None of the patients experienced stroke during or after the procedure. The complication rate was low, with no thromboembolic events and 2.1% of patients experiencing a major bleeding event. Conclusions: Omitting NOAC 24 h before the ablation might be safe if combined with left atrial thrombus exclusion with computed tomography.<\/jats:p>","DOI":"10.3390\/life14010133","type":"journal-article","created":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T07:41:28Z","timestamp":1705477288000},"page":"133","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["One-Day Interruption of NOAC Is Associated with Low Risk of Periprocedural Adverse Events during Pulmonary Vein Isolation If Combined with Left Atrial Thrombus Exclusion with Computed Tomography"],"prefix":"10.3390","volume":"14","author":[{"given":"Katalin","family":"Piros","sequence":"first","affiliation":[{"name":"Heart and Vascular Center, Semmelweis University, V\u00e1rosmajor Street 68, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adorj\u00e1n","family":"Vida","sequence":"additional","affiliation":[{"name":"Heart and Vascular Center, Semmelweis University, V\u00e1rosmajor Street 68, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5670-745X","authenticated-orcid":false,"given":"N\u00e1ndor","family":"Szegedi","sequence":"additional","affiliation":[{"name":"Heart and Vascular Center, Semmelweis University, V\u00e1rosmajor Street 68, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P\u00e9ter","family":"Perge","sequence":"additional","affiliation":[{"name":"Heart and Vascular Center, Semmelweis University, V\u00e1rosmajor Street 68, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2320-3535","authenticated-orcid":false,"given":"Zolt\u00e1n","family":"Sall\u00f3","sequence":"additional","affiliation":[{"name":"Heart and Vascular Center, Semmelweis University, V\u00e1rosmajor Street 68, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5648-9462","authenticated-orcid":false,"given":"Arnold B\u00e9la","family":"Ferencz","sequence":"additional","affiliation":[{"name":"Heart and Vascular Center, Semmelweis University, V\u00e1rosmajor Street 68, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivien Klaudia","family":"Nagy","sequence":"additional","affiliation":[{"name":"Heart and Vascular Center, Semmelweis University, V\u00e1rosmajor Street 68, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0211-0399","authenticated-orcid":false,"given":"Szilvia","family":"Herczeg","sequence":"additional","affiliation":[{"name":"Heart and Vascular Center, Semmelweis University, V\u00e1rosmajor Street 68, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P\u00e1l","family":"\u00c1brah\u00e1m","sequence":"additional","affiliation":[{"name":"Heart and Vascular Center, Semmelweis University, V\u00e1rosmajor Street 68, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0826-7888","authenticated-orcid":false,"given":"Csaba","family":"Csobay-Nov\u00e1k","sequence":"additional","affiliation":[{"name":"Heart and Vascular Center, Semmelweis University, V\u00e1rosmajor Street 68, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zs\u00f3fia","family":"Drobni","sequence":"additional","affiliation":[{"name":"Heart and Vascular Center, Semmelweis University, V\u00e1rosmajor Street 68, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tam\u00e1s","family":"Tahin","sequence":"additional","affiliation":[{"name":"Heart and Vascular Center, Semmelweis University, V\u00e1rosmajor Street 68, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-7298-7202","authenticated-orcid":false,"given":"Gy\u00f6rgyi","family":"Apponyi","sequence":"additional","affiliation":[{"name":"Heart and Vascular Center, Semmelweis University, V\u00e1rosmajor Street 68, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B\u00e9la","family":"Merkely","sequence":"additional","affiliation":[{"name":"Heart and Vascular Center, Semmelweis University, V\u00e1rosmajor Street 68, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3","family":"Gell\u00e9r","sequence":"additional","affiliation":[{"name":"Heart and Vascular Center, Semmelweis University, V\u00e1rosmajor Street 68, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8209-990X","authenticated-orcid":false,"given":"Istv\u00e1n","family":"Osztheimer","sequence":"additional","affiliation":[{"name":"Heart and Vascular Center, Semmelweis University, V\u00e1rosmajor Street 68, 1122 Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,1,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1161\/01.STR.22.8.983","article-title":"Atrial fibrillation as an independent risk factor for stroke: The Framingham 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PLoS ONE, 16.","key":"ref_7","DOI":"10.1371\/journal.pone.0256317"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1093\/europace\/euy326","article-title":"Repeat procedure is a new independent predictor of complications of atrial fibrillation ablation","volume":"21","author":"Szegedi","year":"2019","journal-title":"Europace"},{"doi-asserted-by":"crossref","unstructured":"Szegedi, N., Sall\u00f3, Z., Perge, P., Piros, K., Nagy, V.K., Osztheimer, I., Merkely, B., and Gell\u00e9r, L. (2021). The role of local impedance drop in the acute lesion efficacy during pulmonary vein isolation performed with a new contact force sensing catheter-A pilot study. 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