{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:53:00Z","timestamp":1787028780225,"version":"build-2736575974"},"reference-count":36,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T00:00:00Z","timestamp":1719532800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Pruritus is an important symptom among patients affected by psoriasis. To date, no general agreement has been established regarding pruritus as a measure of psoriasis severity. This study aims to assess psoriatic pruritis prevalence and characteristics using a comprehensive itch questionnaire. A semi-structured questionnaire consisting of 48 questions was applied to patients diagnosed with psoriasis and admitted to the Dermatology Department of Mures Clinical County Hospital, Romania. A total of 163 patients were enrolled, out of which 115 (70.55%) reported itch. Patients with itch had higher PASI (p = 0.003) and DLQI scores (p &lt; 0.001). The itch was most frequently described as a crawling sensation, mainly located in the lesional skin and aggravated by stress and temperature variation. It had a moderate intensity (6.18 \u00b1 2.46). Emollients were the treatment preferred by most patients in alleviating itch, while biologics exerted a protective effect on itch development (OR = \u22120.24; p &lt; 0.0001) and negatively correlated with itch intensity (r = \u22120.23; p &lt; 0.0001). Advanced age, high BMI, and PASI scores were indicators of itch presence, while female gender, high PASI score, and frequent itch episodes indicate highly intense pruritus (\u22657 on the VAS). A better understanding of itch and its clinical features will guide physicians toward the best treatment option and would, ultimately, benefit the patient.<\/jats:p>","DOI":"10.3390\/life14070827","type":"journal-article","created":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T04:23:43Z","timestamp":1719980623000},"page":"827","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Predicting Factors and Clinical Characteristics of Pruritus in Psoriasis: A Cross-Sectional Survey"],"prefix":"10.3390","volume":"14","author":[{"given":"Silviu-Horia","family":"Morariu","sequence":"first","affiliation":[{"name":"Dermatology Department, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 540142 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ovidiu Simion","family":"Cotoi","sequence":"additional","affiliation":[{"name":"Pathophysiology Department, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 540142 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oana Mirela","family":"Tiuc\u0103","sequence":"additional","affiliation":[{"name":"Dermatology Department, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 540142 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mircea","family":"Ambros","sequence":"additional","affiliation":[{"name":"Dermatology Clinic, Mures Clinical County Hospital, 540342 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxana-Ioana","family":"Ilcu\u0219","sequence":"additional","affiliation":[{"name":"Dermatology Clinic, Mures Clinical County Hospital, 540342 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liuba","family":"Garaga","sequence":"additional","affiliation":[{"name":"Dermatology Clinic, Mures Clinical County Hospital, 540342 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ailinc\u0103i","family":"Raluca","sequence":"additional","affiliation":[{"name":"Dermatology Clinic, Mures Clinical County Hospital, 540342 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Horea","sequence":"additional","affiliation":[{"name":"Dermatology Clinic, Mures Clinical County Hospital, 540342 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreea-Beatrix","family":"B\u0103lan","sequence":"additional","affiliation":[{"name":"Dermatology Clinic, Mures Clinical County Hospital, 540342 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u0103d\u0103lina","family":"Husariu","sequence":"additional","affiliation":[{"name":"Dermatology Clinic, Mures Clinical County Hospital, 540342 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anca","family":"G\u00eenj","sequence":"additional","affiliation":[{"name":"Dermatology Clinic, Mures Clinical County Hospital, 540342 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"\u021aiplic","sequence":"additional","affiliation":[{"name":"Dermatology Clinic, Mures Clinical County Hospital, 540342 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Hidi","sequence":"additional","affiliation":[{"name":"Dermatology Clinic, Mures Clinical County Hospital, 540342 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biborka","family":"Szabo","sequence":"additional","affiliation":[{"name":"Dermatology Clinic, Mures Clinical County Hospital, 540342 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radu Alexandru","family":"Stan","sequence":"additional","affiliation":[{"name":"Dermatology Clinic, Mures Clinical County Hospital, 540342 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alin Codru\u021b","family":"Nicolescu","sequence":"additional","affiliation":[{"name":"Agrippa Ionescu Emergency Clinical Hospital, 011773 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,28]]},"reference":[{"key":"ref_1","unstructured":"WHO Organization (2016). 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