{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:22:52Z","timestamp":1760145772192,"version":"build-2065373602"},"reference-count":53,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T00:00:00Z","timestamp":1724976000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Despite rapid advances in colorectal surgery, morbidity and mortality rates in elective gastrointestinal surgery play a significant role. For decades, there have been tempestuous discussions on preventative measures to minimize the risk of anastomotic dehiscence. When mechanical bowel preparation before an elective procedure, one of the key hypotheses, was introduced into practice, it was assumed that it would decrease the number of infectious complications and anastomotic dehiscence. The advancements in antibiotic treatment supported the concomitant administration of oral antibiotics and mechanical bowel preparation. In the prospective study conducted at our clinic, we performed left-side colorectal procedures without prior mechanical preparation. All patients enrolled in the study underwent the surgery and were observed in the 3rd Surgical Clinic, Faculty of Medicine, Comenius University in Bratislava, Slovakia, from January 2019 to January 2020. As a control group, we used a similar group of patients with MBP. Our observed group included 87 patients with tumors in the left part of their large intestine (lineal flexure, descendent colon, sigmoid colon, and rectum). Dixon laparoscopic resection was performed in 26 patients. Sigmoid laparoscopic resection was performed in 27 patients. In 12 patients, the procedure was started laparoscopically but had to be converted due to adverse anatomical conditions. The conservative approaches mostly included Dixon resections (19 patients), sigmoid colon resections (5 patients), left-side hemicolectomies (6 patients), and Miles\u2019 tumor resections, with rectal amputation (4 patients). Our study highlighted the fact that MBP does not have an unequivocal benefit for patients with colorectal infection, which has an impact on the development of anastomotic dehiscence.<\/jats:p>","DOI":"10.3390\/life14091092","type":"journal-article","created":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T06:46:29Z","timestamp":1725000389000},"page":"1092","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Pre-Operative Mechanical Bowel Preparation Does Not Affect the Impact of Anastomosis Leakage in Left-Side Colorectal Surgery\u2014A Single Center Observational Study"],"prefix":"10.3390","volume":"14","author":[{"given":"Ludov\u00edt","family":"Danihel","sequence":"first","affiliation":[{"name":"3rd Surgical Clinic, Faculty of Medicine, Comenius University in Bratislava, 814 99 Bratislava, Slovakia"},{"name":"Surgical Department, Bory Penta Hospitals, 841 03 Bratislava, Slovakia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marian","family":"Cerny","sequence":"additional","affiliation":[{"name":"Klinik f\u00fcr Allgemein-, Viszeral-, Thorax-, Adipositas-, Gef\u00e4\u00df-und Kinderchirurgie, 94032 Passau, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivor","family":"Dropco","sequence":"additional","affiliation":[{"name":"Klinik und Poliklinik f\u00fcr Chirurgie, Universit\u00e4tsklinikum Regensburg, 93053 Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petra","family":"Zrnikova","sequence":"additional","affiliation":[{"name":"Medicalen, 036 01 Martin, Slovakia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milan","family":"Schnorrer","sequence":"additional","affiliation":[{"name":"3rd Surgical Clinic, Faculty of Medicine, Comenius University in Bratislava, 814 99 Bratislava, Slovakia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marek","family":"Smolar","sequence":"additional","affiliation":[{"name":"Clinic of General, Visceral and Transplant Surgery, Jessenius Faculty of Medicine, Martin, Comenius University in Bratislava, 813 72 Bratislava, Slovakia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miloslav","family":"Misanik","sequence":"additional","affiliation":[{"name":"Clinic of General, Visceral and Transplant Surgery, Jessenius Faculty of Medicine, Martin, Comenius University in Bratislava, 813 72 Bratislava, Slovakia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Durdik","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, Faculty of Medicine, Comenius University in Bratislava, 813 72 Bratislava, Slovakia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,8,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.jamcollsurg.2008.10.015","article-title":"Colonic anastomonic leak:risk factors, diagnosis, and treatment","volume":"208","author":"Kingham","year":"2009","journal-title":"J. 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