{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:37:14Z","timestamp":1786725434992,"version":"build-2736575974"},"reference-count":37,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T00:00:00Z","timestamp":1725494400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Technology Transfer and Commercialization Program through the INNOPOLIS Foundation, funded by the Ministry of Science and ICT","award":["2023-GJ-RD-0006"],"award-info":[{"award-number":["2023-GJ-RD-0006"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Background: Despite the effectiveness of cardiac rehabilitation (CR), the actual participation rate in CR is low. While home-based CR offers a viable alternative, it faces challenges in participation due to factors such as a lack of self-motivation and fear of exercising without supervision. Utilizing a mobile healthcare application (app) during counseling may be an effective strategy for patients. Therefore, the aim of this study was to assess whether 6 weeks of home-based CR with exercise readjustment using a mobile app is an effective therapy for patients with acute myocardial infarction (AMI). Methods: Post-AMI patients eligible for home-based CR were randomized into the intervention group (CR-Mobile) and the control group, which followed the usual home-based CR protocol (CR-Usual). Both groups participated in a 6-week home-based CR program, with exercise readjustment and encouragement carried out every 2 weeks. The CR-Mobile group was supervised using data recorded in the mobile app, while the CR-Usual group was supervised via phone consultations. The primary outcome measured was maximal oxygen consumption (VO2max). Results: Within-group comparisons showed significant improvements in VO2max (PCR-Mobile = 0.011 vs. PCR-Usual = 0.020) and METs (PCR-Mobile = 0.011 vs. PCR-Usual = 0.011) for both groups. Conclusions: These findings suggest that a 6-week home-based CR program with exercise readjustment using a mobile app can potentially enhance exercise capacity as effectively as verbal supervision.<\/jats:p>","DOI":"10.3390\/life14091122","type":"journal-article","created":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T11:15:59Z","timestamp":1725534959000},"page":"1122","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Effectiveness of Home-Based Cardiac Rehabilitation with Optimized Exercise Prescriptions Using a Mobile Healthcare App in Patients with Acute Myocardial Infarction: A Randomized Controlled Trial"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5626-8135","authenticated-orcid":false,"given":"Hyun-Seok","family":"Jo","sequence":"first","affiliation":[{"name":"Department of Physical & Rehabilitation Medicine, Chonnam National University Hospital, Gwangju 61469, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7404-299X","authenticated-orcid":false,"given":"Hyeong-Min","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Physical & Rehabilitation Medicine, Chonnam National University Hospital, Gwangju 61469, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chae-Hyun","family":"Go","sequence":"additional","affiliation":[{"name":"Regional CardioCerebroVascular Center, Chonnam National University Hospital, Gwangju 61469, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hae-Young","family":"Yu","sequence":"additional","affiliation":[{"name":"Biomedical Research Institute, Chonnam National University Hospital, Gwangju 61469, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3769-6227","authenticated-orcid":false,"given":"Hyeng-Kyu","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Physical & Rehabilitation Medicine, Regional CardioCerebroVascular Center, Chonnam National University Medical School & Hospital, Gwangju 61469, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1672-8875","authenticated-orcid":false,"given":"Jae-Young","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Physical & Rehabilitation Medicine, Regional CardioCerebroVascular Center, Center for Aging and Geriatrics, Chonnam National University Medical School & Hospital, Gwangju 61469, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,9,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1016\/S0140-6736(18)32203-7","article-title":"GBD 2017 Causes of Death Collaborators Global, Regional, and National Age-Sex-Specific Mortality for 282 Causes of Death in 195 Countries and Territories, 1980\u20132017: A Systematic Analysis for the Global Burden of Disease Study 2017","volume":"392","author":"Harikrishnan","year":"2018","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"202","DOI":"10.4070\/kcj.2015.45.3.202","article-title":"Thirty-Year Trends in Mortality from Cardiovascular Diseases in Korea","volume":"45","author":"Lee","year":"2015","journal-title":"Korean Circ. J."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"748","DOI":"10.5124\/jkma.2022.65.11.748","article-title":"Statistical Analysis of the Cause of Death in Korea in 2019","volume":"65","author":"Noh","year":"2022","journal-title":"J. Korean Med. Assoc."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1038\/s41569-021-00611-7","article-title":"The Role of Cardiac Rehabilitation in Improving Cardiovascular Outcomes","volume":"19","author":"Taylor","year":"2022","journal-title":"Nat. Rev. Cardiol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1161\/CIRCULATIONAHA.107.701466","article-title":"Use of Cardiac Rehabilitation by Medicare Beneficiaries after Myocardial Infarction or Coronary Bypass Surgery","volume":"116","author":"Suaya","year":"2007","journal-title":"Circulation"},{"key":"ref_6","unstructured":"(2008). Centers for Disease Control and Prevention (CDC) Receipt of Outpatient Cardiac Rehabilitation among Heart Attack Survivors\u2014United States, 2005. MMWR Morb. Mortal. Wkly. Rep., 57, 89\u201394."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"e262","DOI":"10.3346\/jkms.2020.35.e262","article-title":"Underutilization of Hospital-Based Cardiac Rehabilitation after Acute Myocardial Infarction in Korea","volume":"35","author":"Kim","year":"2020","journal-title":"J. Korean Med. Sci."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"318","DOI":"10.5535\/arm.23050","article-title":"Fact Sheet on Cardiac Rehabilitation for Cardiovascular Disease in South Korea","volume":"47","author":"Kim","year":"2023","journal-title":"Ann. Rehabil. Med."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"McDonagh, S.T., Dalal, H., Moore, S., Clark, C.E., Dean, S.G., Jolly, K., and Taylor, R.S. (2023). Home-Based versus Centre-Based Cardiac Rehabilitation. Cochrane Database Syst. Rev., 10.","DOI":"10.1002\/14651858.CD007130.pub5"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Brito, J., Aguiar-Ricardo, I., Alves Da Silva, P., Valente Da Silva, B., Cunha, N., Couto Pereira, S., Silverio Antonio, P., Pinto, R., Lemos Pires, M., and Santos, O. (2021). Home-Based Cardiac Rehabilitation\u2014the Real Barriers of Programs at Distance. Eur. J. Prev. Cardiol., 28.","DOI":"10.1093\/eurjpc\/zwab061.336"},{"key":"ref_11","first-page":"749","article-title":"Predictors of Adherence to Home-Based Cardiac Rehabilitation Program among Coronary Artery Disease Outpatients in China","volume":"16","author":"Ge","year":"2019","journal-title":"J. Geriatr. Cardiol. JGC"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Ravn, M.B., Uhd, M., Svendsen, M.L., \u00d8rtenblad, L., and Maribo, T. (2022). How to Facilitate Adherence to Cardiac Rehabilitation in Primary Health Settings for Ischaemic Heart Disease Patients. Perspect. Health. Prof. Front. Rehabil. Sci., 3.","DOI":"10.3389\/fresc.2022.837175"},{"key":"ref_13","unstructured":"AACVPR (2020). Guidelines for Cardiac Rehabilitation Programs, Human Kinetics."},{"key":"ref_14","first-page":"328","article-title":"ACSM\u2019s Guidelines for Exercise Testing and Prescription 9th Ed 2014.","volume":"58","author":"Ferguson","year":"2014","journal-title":"J. Can. Chiropr. Assoc."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1249\/00005768-198205000-00012","article-title":"Psychophysical Bases of Perceived Exertion","volume":"14","author":"Borg","year":"1982","journal-title":"Med. Sci. Sports. Exerc."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.3758\/BRM.41.4.1149","article-title":"Statistical Power Analyses Using G*Power 3.1: Tests for Correlation and Regression Analyses","volume":"41","author":"Faul","year":"2009","journal-title":"Behav. Res. Methods"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1161\/01.CIR.0000091080.57509.E9","article-title":"Exercise Capacity and the Risk of Death in Women: The St James Women Take Heart Project","volume":"108","author":"Gulati","year":"2003","journal-title":"Circulation"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.pcad.2014.09.011","article-title":"Physical Activity and Cardiorespiratory Fitness as Major Markers of Cardiovascular Risk: Their Independent and Interwoven Importance to Health Status","volume":"57","author":"Myers","year":"2015","journal-title":"Prog. Cardiovasc. Dis."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1056\/NEJMoa011858","article-title":"Exercise Capacity and Mortality among Men Referred for Exercise Testing","volume":"346","author":"Myers","year":"2002","journal-title":"N. Engl. J. Med."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.1161\/01.CIR.100.17.1764","article-title":"Results of a Multicenter Randomized Clinical Trial of Exercise and Long-Term Survival in Myocardial Infarction Patients: The National Exercise and Heart Disease Project (NEHDP)","volume":"100","author":"Dorn","year":"1999","journal-title":"Circulation"},{"key":"ref_21","unstructured":"(2024, June 21). Effect of Smartphone-Based Telemonitored Exercise Rehabilitation among Patients with Coronary Heart Disease, Available online: https:\/\/pubmed.ncbi.nlm.nih.gov\/31820334\/."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1007\/s11136-012-0322-4","article-title":"Measurement Properties of the EQ-5D-5L Compared to the EQ-5D-3L across Eight Patient Groups: A Multi-Country Study","volume":"22","author":"Janssen","year":"2013","journal-title":"Qual. Life. Res."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.4070\/kcj.2000.30.8.1004","article-title":"Development of Korean Activity Scale\/Index (KASI)","volume":"30","author":"Sung","year":"2000","journal-title":"Korean Circ. J."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1046\/j.1525-1497.2001.016009606.x","article-title":"The PHQ-9","volume":"16","author":"Kroenke","year":"2001","journal-title":"J. Gen. Intern. Med."},{"key":"ref_25","first-page":"CD001800","article-title":"Exercise-Based Cardiac Rehabilitation for Coronary Heart Disease","volume":"2016","author":"Heran","year":"2011","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1016\/j.jacc.2008.01.030","article-title":"Current Status of Cardiac Rehabilitation","volume":"51","author":"Wenger","year":"2008","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jacc.2009.01.078","article-title":"Cardiac Rehabilitation and Survival in Older Coronary Patients","volume":"54","author":"Suaya","year":"2009","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1139\/h11-151","article-title":"Adherence to a Cardiac Rehabilitation Home Program Model of Care: A Comparison to a Well-Established Traditional on-Site Supervised Program","volume":"37","author":"Scane","year":"2012","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"e000418","DOI":"10.1161\/JAHA.113.000418","article-title":"Cardiac Rehabilitation Patient and Organizational Factors: What Keeps Patients in Programs?","volume":"2","author":"Oldridge","year":"2013","journal-title":"J. Am. Heart. Assoc."},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"JMIRx Med (2024, June 19). Use of Smartphone Apps for Improving Physical Function Capacity in Cardiac Patient Rehabilitation: Systematic Review. Available online: https:\/\/xmed.jmir.org\/2021\/3\/e21906.","DOI":"10.2196\/21906"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1080\/09593985.2019.1620388","article-title":"Barriers to Participation in Center-Based Cardiac Rehabilitation Programs and Patients\u2019 Attitude toward Home-Based Cardiac Rehabilitation Programs","volume":"37","author":"Bakhshayeh","year":"2021","journal-title":"Physiother. Theory Pract."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1161\/01.CIR.0000024413.15949.ED","article-title":"Prediction of Long-Term Prognosis in 12,169 Men Referred for Cardiac Rehabilitation","volume":"106","author":"Kavanagh","year":"2002","journal-title":"Circulation"},{"key":"ref_33","unstructured":"(2024, June 19). Digital Literacy among Korean Older Adults: A Scoping Review of Quantitative Studies, Available online: https:\/\/pubmed.ncbi.nlm.nih.gov\/37654708\/."},{"key":"ref_34","unstructured":"National Knowledge Information System (2024, June 19). Available online: https:\/\/www.nkis.re.kr\/subject_view1.do?otpId=OTP_0000000000006532&otpSeq=0&eoSeq=0."},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Zheng, Y., Zhou, L., Qin, S., Guo, J., and Qin, B. (2024). The Impact of Home Cardiac Rehabilitation on Quality of Life and Psychological Well-Being in Patients with Coronary Heart Disease: A Randomized Controlled Study. Med. Sci. Monit. Int. Med. J. Exp. Clin. Res., 30.","DOI":"10.12659\/MSM.942803"},{"key":"ref_36","first-page":"124","article-title":"Effects of Exercise Rehabilitation on Blood Pressure of Patients after Myocardial Infarction","volume":"1","author":"Kargarfard","year":"2010","journal-title":"Int. J. Prev. Med."},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Peng, K., Li, X., Wang, Z., Li, M., and Yang, Y. (2022). Association of Low-Density Lipoprotein Cholesterol Levels with the Risk of Mortality and Cardiovascular Events: A Meta-Analysis of Cohort Studies with 1,232,694 Participants. Medicine, 101.","DOI":"10.1097\/MD.0000000000032003"}],"container-title":["Life"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-1729\/14\/9\/1122\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:49:21Z","timestamp":1760111361000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-1729\/14\/9\/1122"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,5]]},"references-count":37,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2024,9]]}},"alternative-id":["life14091122"],"URL":"https:\/\/doi.org\/10.3390\/life14091122","relation":{},"ISSN":["2075-1729"],"issn-type":[{"value":"2075-1729","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,5]]}}}