{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:25:16Z","timestamp":1760145916785,"version":"build-2065373602"},"reference-count":41,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T00:00:00Z","timestamp":1725840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009687","name":"Wroclaw Medical University","doi-asserted-by":"publisher","award":["SUBZ.E264.24.033"],"award-info":[{"award-number":["SUBZ.E264.24.033"]}],"id":[{"id":"10.13039\/501100009687","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>Objectives: this study aims to evaluate the prevalence of various arrhythmias and other electrocardiographic patterns within the group of individuals with overweight and obesity. Methods: One hundred eighty-one adults (90 females and 91 males) were qualified for inclusion in the experimental group. All participants had a body mass index (BMI) exceeding 25 kg\/m2 (98 patients with obesity and 83 with overweight). The mean BMI in the obesity group was 33.6 kg\/m2, and all participants had class 1 obesity. The control group comprised 69 individuals (56 females and 13 males) with normal BMI. The basic measurements were performed, and the participants filled out questionnaires describing their health conditions and lifestyles. Each participant underwent an electrocardiographic (ECG) examination and a 24 h Holter ECG examination. Results: In patients with class 1 obesity compared to the control patients, the average numbers of premature ventricular beats (PVBs) and premature supraventricular beats (SPBs) were statistically significantly higher (p = 0.030 and p = 0.042). There was a positive correlation between body weight and PVB (p = 0.028) and between body weight and SPB (p = 0.028). Moreover, BMI and waist circumference were correlated with SPB (p = 0.043 and p = 0.031). In the backward stepwise multivariate regression model considering 24 h Holter ECG monitoring, concerning SPB as the dependent variable, it was observed that BMI (especially obesity class 1), type 2 diabetes, and thyroid disease exhibited the highest regression coefficients. Conclusions: obesity, even in class 1, might be a factor in a more frequent occurrence of abnormalities in electrocardiographic tests.<\/jats:p>","DOI":"10.3390\/life14091140","type":"journal-article","created":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T03:16:51Z","timestamp":1725938211000},"page":"1140","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Prevalence of Arrhythmias, Including Premature Supraventricular and Ventricular Beats and Other Electrocardiographic Patterns, in 24-Hour Holter Monitoring in Patients with Overweight and Obesity"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3262-8567","authenticated-orcid":false,"given":"Irena Anna","family":"Dykiert","sequence":"first","affiliation":[{"name":"Department of Physiology and Pathophysiology, Division of Pathophysiology, Wroclaw Medical University, 50-368 Wroc\u0142aw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-0987-4225","authenticated-orcid":false,"given":"Krzysztof","family":"Kraik","sequence":"additional","affiliation":[{"name":"Students\u2019 Scientific Association of Cardiovascular Diseases Prevention, Wroclaw Medical University, 50-368 Wroc\u0142aw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lidia","family":"Jurczenko","sequence":"additional","affiliation":[{"name":"Students\u2019 Scientific Association of Cardiovascular Diseases Prevention, Wroclaw Medical University, 50-368 Wroc\u0142aw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8366-0239","authenticated-orcid":false,"given":"Pawe\u0142","family":"Ga\u0107","sequence":"additional","affiliation":[{"name":"Department of Environmental Health, Occupational Medicine and Epidemiology, Wroclaw Medical University, 50-345 Wroc\u0142aw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafa\u0142","family":"Por\u0119ba","sequence":"additional","affiliation":[{"name":"Department and Clinic of Angiology and Internal Medicine, Wroclaw Medical University, 50-556 Wroc\u0142aw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4868-3088","authenticated-orcid":false,"given":"Ma\u0142gorzata","family":"Por\u0119ba","sequence":"additional","affiliation":[{"name":"Department of Paralympic Sport, Wroclaw University of Health and Sport Sciences, 51-617 Wroc\u0142aw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,9,9]]},"reference":[{"key":"ref_1","unstructured":"World Health Organization (2024, August 10). Obesity and Overweight. Available online: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/obesity-and-overweight."},{"key":"ref_2","unstructured":"Eurostat Report (2024, August 08). Over Half of Adults in the EU Are Overweight. Available online: https:\/\/ec.europa.eu\/eurostat\/statistics-explained\/index.php?title=Overweight_and_obesity_-_BMI_statistics#Obesity_by_age_group."},{"key":"ref_3","unstructured":"(2024, August 08). Raport: Odsetek Os\u00f3b w Wieku Powy\u017cej 15 Lat Wed\u0142ug Indeksu Masy Cia\u0142a (BMI), GUS, Available online: https:\/\/stat.gov.pl\/obszary-tematyczne\/zdrowie\/zdrowie\/odsetek-osob-w-wieku-powyzej-15-lat-wedlug-indeksu-masy-ciala-bmi,23,1.html."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.jjcc.2015.04.002","article-title":"Obesity and atrial fibrillation: A comprehensive review of the pathophysiological mechanisms and links","volume":"66","author":"Goudis","year":"2015","journal-title":"J. Cardiol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1016\/j.jacc.2017.09.002","article-title":"Obesity and Atrial Fibrillation Prevalence, Pathogenesis, and Prognosis: Effects of Weight Loss and Exercise","volume":"70","author":"Lavie","year":"2017","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_6","first-page":"e46232","article-title":"Impact of Weight Loss on Atrial Fibrillation","volume":"15","author":"Ahammed","year":"2023","journal-title":"Cureus"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1161\/CIRCULATIONAHA.113.001840","article-title":"Obesity begets atrial fibrillation: A contemporary summary","volume":"128","author":"Magnani","year":"2013","journal-title":"Circulation"},{"key":"ref_8","unstructured":"(2024, August 08). A Healthy Lifestyle\u2014WHO Recommendations. Available online: https:\/\/www.who.int\/europe\/news-room\/fact-sheets\/item\/a-healthy-lifestyle---who-recommendations."},{"key":"ref_9","unstructured":"(2024, August 08). Waist Circumference and Waist-Hip Ratio: Report of a WHO Expert Consultation. Available online: https:\/\/www.who.int\/publications\/i\/item\/9789241501491."},{"key":"ref_10","unstructured":"(1996). Heart rate variability: Standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Circulation, 93, 1043\u20131065."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s40519-023-01630-8","article-title":"ANMCO (Italian Association of Hospital Cardiologists) scientific statement: Obesity in adults-an approach for cardiologists","volume":"29","author":"Mocini","year":"2024","journal-title":"Eat Weight Disord."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Templin, T., Cravo Oliveira Hashiguchi, T., Thomson, B., Dieleman, J., and Bendavid, E. (2019). The overweight and obesity transition from the wealthy to the poor in low- and middle-income countries: A survey of household data from 103 countries. PLoS Med., 16.","DOI":"10.1371\/journal.pmed.1002968"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/jcph.2193","article-title":"Prevalence of Baseline Cardiac Arrhythmias in Participants with Overweight or Obesity in Phase 1 Clinical Trials: Analysis of 24-Hour Holter Electrocardiogram Recordings","volume":"63","author":"Skovgaard","year":"2023","journal-title":"J. Clin. Pharmacol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1002\/jcph.679","article-title":"Arrhythmias Seen in Baseline 24-Hour Holter ECG Recordings in Healthy Normal Volunteers During Phase 1 Clinical Trials","volume":"56","author":"Hingorani","year":"2016","journal-title":"J. Clin. Pharmacol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"e12424","DOI":"10.1111\/cob.12424","article-title":"Assessment of arrhythmias cardiac autonomic tone at a relatively young age patients with obesity class, I.I.I","volume":"11","author":"Bienias","year":"2021","journal-title":"Clin. Obes."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Binu, A.J., Srinath, S.C., Cherian, K.E., Jacob, J.R., Paul, T.V., and Kapoor, N. (2022). A Pilot Study of Electrocardiographic Features in Patients with Obesity from a Tertiary Care Centre in Southern India (Electron). Med. Sci., 10.","DOI":"10.3390\/medsci10040056"},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Yao, Y., Xue, J., and Li, B. (2022). Obesity and sudden cardiac death: Prevalence, pathogenesis, prevention and intervention. Front. Cell Dev. Biol., 10.","DOI":"10.3389\/fcell.2022.1044923"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"5374176","DOI":"10.1155\/2017\/5374176","article-title":"Cardiac Autonomic Neuropathy: Why Should Cardiologists Care about That?","volume":"2017","author":"Bissinger","year":"2017","journal-title":"J. Diabetes Res."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1159\/000446915","article-title":"The Association between Central Adiposity and Autonomic Dysfunction in Obesity","volume":"25","author":"Yaylali","year":"2016","journal-title":"Med. Princ. Pract."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1186\/s12933-021-01356-w","article-title":"Autonomic nervous system activity changes in patients with hypertension and overweight: Role and therapeutic implications","volume":"20","author":"Valensi","year":"2021","journal-title":"Cardiovasc. Diabetol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"H1530","DOI":"10.1152\/ajpheart.00196.2013","article-title":"Sympathetic cardiac hyperinnervation and atrial autonomic imbalance in diet-induced obesity promote cardiac arrhythmias","volume":"305","author":"McCully","year":"2013","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"57","DOI":"10.2147\/DMSO.S123935","article-title":"Association between obesity and heart rate variability indices: An intuition toward cardiac autonomic alteration\u2014A risk of CVD","volume":"10","author":"Yadav","year":"2017","journal-title":"Diabetes Metab. Syndr. Obes."},{"key":"ref_23","first-page":"320","article-title":"Autonomic function and its relationship with central obesity and hemodynamic variables in obese and overweight adults","volume":"39","author":"Brito","year":"2022","journal-title":"Nutr. Hosp."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"55","DOI":"10.3349\/ymj.2013.54.1.55","article-title":"Differential association of adiposity measures with heart rate variability measures in Koreans","volume":"54","author":"Yi","year":"2013","journal-title":"Yonsei Med. J."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Chang, W.P., Wang, C.H., and Lin, Y.K. (2021). Influence of Obesity on Heart Rate Variability in Nurses with Age and Shift Type as Moderators. Biomed. Res. Int., 2021.","DOI":"10.1155\/2021\/8119929"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1586\/14779072.2014.952283","article-title":"Sudden cardiac death and obesity","volume":"12","author":"Plourde","year":"2014","journal-title":"Expert Rev Cardiovasc Ther."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1038\/oby.2000.31","article-title":"Prevalence of sleep apnea and electrocardiographic disturbances in morbidly obese patients","volume":"8","author":"Orea","year":"2000","journal-title":"Obes. Res."},{"key":"ref_28","first-page":"e31205","article-title":"Obesity and Atrial Fibrillation: A Narrative Review","volume":"14","author":"Gupta","year":"2022","journal-title":"Cureus"},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Mariani, M.V., Pierucci, N., Trivigno, S., Cipollone, P., Piro, A., Chimenti, C., Della Rocca, D.G., Miraldi, F., Vizza, C.D., and Lavalle, C. (2024). Probability Score to Predict. Spontaneous Conversion to Sinus Rhythm. in Patients with Symptomatic Atrial Fibrillation When Less Could Be More?. J. Clin. Med., 13.","DOI":"10.3390\/jcm13051470"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1038\/nrendo.2014.44","article-title":"The pathophysiology of hypertension in patients with obesity","volume":"10","author":"DeMarco","year":"2014","journal-title":"Nat. Rev. Endocrinol."},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Martelli, D., and Brooks, V.L. (2023). Leptin Increases: Physiological Roles in the Control of Sympathetic Nerve Activity, Energy Balance, and the Hypothalamic-Pituitary-Thyroid Axis. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms24032684"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"e000308","DOI":"10.1136\/bmjmed-2022-000308","article-title":"Obesity as a risk factor for cardiac arrhythmias","volume":"1","author":"Patel","year":"2022","journal-title":"BMJ Med."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"2471","DOI":"10.1001\/jama.292.20.2471","article-title":"Obesity and the risk of new-onset atrial fibrillation","volume":"292","author":"Wang","year":"2004","journal-title":"JAMA"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"2319","DOI":"10.1016\/j.jacc.2010.02.029","article-title":"The long- and short-term impact of elevated body mass index on the risk of new atrial fibrillation the WHS (women\u2019s health study)","volume":"55","author":"Tedrow","year":"2010","journal-title":"J. Am. Coll. Cardiol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1161\/CIRCULATIONAHA.110.009035","article-title":"Absolute and attributable risks of atrial fibrillation in relation to optimal and borderline risk factors: The Atherosclerosis Risk in Communities (ARIC) study","volume":"123","author":"Huxley","year":"2011","journal-title":"Circulation"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/j.amjcard.2013.05.065","article-title":"Meta-analysis of ventricular premature complexes and their relation to cardiac mortality in general populations","volume":"112","author":"Ataklte","year":"2013","journal-title":"Am. J. Cardiol."},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Wang, Z., Jiao, S., Chen, J., Guo, H., Ren, L., Sun, L., Sun, Y., and Chen, Y. (2023). The relationship between frequent premature ventricular complexes and epicardial adipose tissue volume. Front. Endocrinol., 14.","DOI":"10.3389\/fendo.2023.1219890"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1136\/heartjnl-2016-309632","article-title":"Risk factors for premature ventricular contractions in young and healthy adults","volume":"103","author":"Aeschbacher","year":"2017","journal-title":"Heart"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1177\/2047487315591442","article-title":"Obesity and exercise-induced ectopic ventricular arrhythmias in apparently healthy middle aged adults","volume":"23","author":"Sabbag","year":"2016","journal-title":"Eur. J. Prev. Cardiol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.hroo.2022.05.008","article-title":"Elevated premature ventricular complex counts on 24-hour electrocardiogram predict incident atrial fibrillation and heart failure-A prospective population-based cohort study","volume":"3","author":"Juhlin","year":"2022","journal-title":"Heart Rhythm. O2"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.4022\/jafib.1724","article-title":"Electrocardiogram (ECG) for the Prediction of Incident Atrial Fibrillation: An Overview","volume":"10","author":"Aizawa","year":"2017","journal-title":"J. Atr. Fibrillation."}],"container-title":["Life"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-1729\/14\/9\/1140\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:52:31Z","timestamp":1760111551000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-1729\/14\/9\/1140"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,9]]},"references-count":41,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2024,9]]}},"alternative-id":["life14091140"],"URL":"https:\/\/doi.org\/10.3390\/life14091140","relation":{},"ISSN":["2075-1729"],"issn-type":[{"type":"electronic","value":"2075-1729"}],"subject":[],"published":{"date-parts":[[2024,9,9]]}}}