{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T18:03:35Z","timestamp":1778004215513,"version":"3.51.4"},"reference-count":24,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T00:00:00Z","timestamp":1731369600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life"],"abstract":"<jats:p>(1) Background: Crossed fused renal ectopia is a rare migration and fusion renal anomaly, more frequently affecting males, with an incidence of between 1:2000 and 1:7500 observed at autopsy. (2) Case presentation: This paper presents the case of a 34-year-old woman, IIIG IIIP, who presented to our clinic for a first-trimester screening evaluation. The risk calculation was performed using the Fetal Medicine Foundation\u2019s first-trimester screening software, version 2.8.1. The screening indicated a low risk for aneuploidies, but the ultrasound scan revealed an empty right renal fossa in the standard coronal section. A more detailed axial examination raised the suspicion of crossed fused renal ectopia. No other anomalies were detected. The morphological scans conducted in the second and third trimesters confirmed and upheld the diagnosis initially established in the first trimester. The fetus did not develop any potential antepartum complications. The patient gave birth via caesarean section at 36 weeks to a live female infant, weighing 3000 g, with an APGAR score of 9 at 1 min. Postnatally, the first trimester diagnosis of the renal malformation was confirmed. (3) Conclusions: Crossed fused renal ectopia, probably the rarest renal migration anomaly, can be diagnosed as early as the first trimester of pregnancy.<\/jats:p>","DOI":"10.3390\/life14111466","type":"journal-article","created":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T05:21:59Z","timestamp":1731388919000},"page":"1466","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Ectopic Kidney, a Challenging First Trimester Diagnosis\u2014Case Report and Literature Review"],"prefix":"10.3390","volume":"14","author":[{"given":"Mircea-Octavian","family":"Poenaru","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Ginecology, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 020021 Bucharest, Romania"},{"name":"Bucur Maternity, St. John Hospital, 040292 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5544-4270","authenticated-orcid":false,"given":"Fernanda-Ecaterina","family":"Augustin","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Ginecology, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 020021 Bucharest, Romania"},{"name":"Bucur Maternity, St. John Hospital, 040292 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ionu\u021b-Didel","family":"V\u00e2lcea","sequence":"additional","affiliation":[{"name":"Bucur Maternity, St. John Hospital, 040292 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9541-3347","authenticated-orcid":false,"given":"Romina-Marina","family":"Sima","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Ginecology, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 020021 Bucharest, Romania"},{"name":"Bucur Maternity, St. John Hospital, 040292 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9665-9103","authenticated-orcid":false,"given":"Mihaela","family":"Amza","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Ginecology, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 020021 Bucharest, Romania"},{"name":"Bucur Maternity, St. John Hospital, 040292 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oana Denisa","family":"B\u0103l\u0103l\u0103u","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Ginecology, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 020021 Bucharest, Romania"},{"name":"Bucur Maternity, St. John Hospital, 040292 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liana","family":"Ple\u0219","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Ginecology, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 020021 Bucharest, Romania"},{"name":"Bucur Maternity, St. John Hospital, 040292 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,12]]},"reference":[{"key":"ref_1","unstructured":"Sadler, T.W. (2019). Urogenital System. Langman\u2019s Medical Embryology, Wolters Kluwer. [14th ed.]."},{"key":"ref_2","unstructured":"Moore, K., Persaud, T., and Torchia, M. (2016). Urogenital System. Before We Are Born: Essentials of Embryology and Birth Defects, Elsevier. [9th ed.]."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1186\/s13256-020-02455-0","article-title":"Incidentally detected pancake kidney: A case report","volume":"14","author":"Bakshi","year":"2020","journal-title":"J. Med. Case Rep."},{"key":"ref_4","first-page":"59","article-title":"Crossed nonfused renal ectopia with variant blood vessels: A rare congenital renal anomaly","volume":"12","author":"Khan","year":"2016","journal-title":"Radiol. Case Rep."},{"key":"ref_5","first-page":"7436097","article-title":"Crossed Unfused Ectopic Pelvic Kidneys: A Case Illustration","volume":"2018","author":"Degheili","year":"2018","journal-title":"Case Rep. Urol."},{"key":"ref_6","unstructured":"Dunnick, N. (2013). Congenital anomalies. Textbook of Uroradiology, Lippicont, Williams and Wilkins. [5th ed.]."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1148\/rg.2021200078","article-title":"Congenital Anomalies of the Upper Urinary Tract: A Comprehensive Review","volume":"41","author":"Houat","year":"2021","journal-title":"Radiographics"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1002\/uog.20844","article-title":"Diagnosis of fetal non-chromosomal abnormalities on routine ultrasound examination at 11\u201313 weeks\u2019 gestation","volume":"54","author":"Syngelaki","year":"2019","journal-title":"Ultrasound Obs. Gynecol."},{"key":"ref_9","unstructured":"The Fetal Medicine Foundation (2024, November 09). The First Trimester Screening (FTS) Programme. Available online: https:\/\/courses.fetalmedicine.com\/software\/Program%20manual-%20Version%202017-281_CE.pdf."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1007\/s00467-011-2098-0","article-title":"Ultrasound mass screening for congenital anomalies of the kidney and urinary tract","volume":"27","author":"Caiulo","year":"2012","journal-title":"Pediatr. Nephrol."},{"key":"ref_11","unstructured":"Partin, A., Dmochowski, R., Kavoussi, R., and Peters, C. (2020). Anomalies of the upper urinary tract. Campbell\u2019s Urology, WB Saunders."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.jpurol.2019.06.019","article-title":"Crossed fused renal ectopia in children: A review of clinical profile, surgical challenges, and outcome","volume":"15","author":"Loganathan","year":"2019","journal-title":"J. Pediatr. Urol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1002\/uog.24888","article-title":"ISUOG Practice Guidelines (updated): Performance of the routine mid-trimester fetal ultrasound scan","volume":"59","author":"Salomon","year":"2022","journal-title":"Ultrasound Obs. Gynecol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1002\/pd.5070","article-title":"Crossed ectopic kidney: Prenatal diagnosis and postnatal follow-up","volume":"37","author":"Zajicek","year":"2016","journal-title":"Prenat. Diagn."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s00192-020-04587-9","article-title":"Embryology of the urogenital tract; a practical overview for urogynecologic surgeons","volume":"32","author":"Tam","year":"2021","journal-title":"Int. Urogynecol J."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"425","DOI":"10.12659\/PJR.894603","article-title":"An Ectopic Pelvic Kidney","volume":"80","author":"Bhoil","year":"2015","journal-title":"Pol. J. Radiol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"7","DOI":"10.4103\/0971-9261.107006","article-title":"Crossed fused renal ectopia: Challenges in diagnosis and management","volume":"18","author":"Solanki","year":"2013","journal-title":"J. Indian. Assoc. Pediatr. Surg."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1016\/j.juro.2009.12.041","article-title":"Urological and nephrological findings of renal ectopia","volume":"183","author":"Beckers","year":"2010","journal-title":"J. Urol."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Carachi, R., and Doss, S.H.E. (2019). The Kidneys and Ureters. Clinical Embryology: An Atlas of Congenital Malformations, Springer.","DOI":"10.1007\/978-3-319-26158-4"},{"key":"ref_20","first-page":"e14365","article-title":"Pelvic Renal Ectopia: Unusual Position Abnormality","volume":"13","author":"Alvarez","year":"2021","journal-title":"Cureus"},{"key":"ref_21","first-page":"594","article-title":"Congenital renal lesions","volume":"23","author":"Garge","year":"2012","journal-title":"Saudi J. Kidney Dis. Transpl."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1097\/RUQ.0b013e3181f573fd","article-title":"Prenatal diagnosis of renal developmental anomalies associated with an empty renal fossa","volume":"26","author":"Oh","year":"2010","journal-title":"Ultrasound Q."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"330","DOI":"10.4081\/aiua.2015.4.330","article-title":"Renal cell carcinoma in patient with crossed fused renal ectopia","volume":"87","author":"Cakmak","year":"2016","journal-title":"Arch. Ital. Urol. Androl."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1038\/s41390-019-0561-y","article-title":"Spectrum of congenital anomalies among VACTERL cases: A EUROCAT population-based study","volume":"87","author":"Marcelis","year":"2020","journal-title":"Pediatr. Res."}],"container-title":["Life"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-1729\/14\/11\/1466\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:30:35Z","timestamp":1760113835000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-1729\/14\/11\/1466"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,12]]},"references-count":24,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2024,11]]}},"alternative-id":["life14111466"],"URL":"https:\/\/doi.org\/10.3390\/life14111466","relation":{},"ISSN":["2075-1729"],"issn-type":[{"value":"2075-1729","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,12]]}}}